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Review: Seroquel and Clonazepam





Summary: drug interactions are reported among people who take Seroquel and Clonazepam together.

This review analyzes the effectiveness and drug interactions between Seroquel and Clonazepam. It is created by eHealthMe based on reports of 7,731 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Seroquel and Clonazepam >>>

What are the drugs

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. (latest outcomes from Seroquel 79,098 users)

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Clonazepam 41,274 users)

On Nov, 25, 2014: 7,731 people who take Seroquel, Clonazepam are studied

Seroquel, Clonazepam outcomes

Drug combinations in study:
- Seroquel (quetiapine fumarate)
- Clonazepam (clonazepam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Seroquel is effective26.83%
(11 of 41 people)
23.44%
(15 of 64 people)
34.38%
(11 of 32 people)
44.44%
(16 of 36 people)
54.55%
(36 of 66 people)
55.56%
(25 of 45 people)
53.33%
(8 of 15 people)
33.33%
(1 of 3 people)
Clonazepam is effective25.00%
(5 of 20 people)
36.67%
(22 of 60 people)
45.71%
(16 of 35 people)
40.43%
(19 of 47 people)
55.00%
(33 of 60 people)
64.71%
(33 of 51 people)
50.00%
(18 of 36 people)
66.67%
(2 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
InsomniaType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusDiabetes Mellitus
SomnolenceDepressionDiabetes MellitusDiabetes MellitusDiabetes MellitusDiabetes MellitusInsomniaType 2 Diabetes Mellitus
Weight IncreasedInsomniaWeight IncreasedDiabetic NeuropathyBlood Cholesterol IncreasedBlood Cholesterol IncreasedSuicidal IdeationWeight Increased
AnxietyDiabetes MellitusHyperglycaemiaHyperlipidaemiaObesityObesityFatigueInsomnia
AgitationSuicidal IdeationBlood Cholesterol IncreasedWeight IncreasedDiabetic NeuropathyDiabetic NeuropathyDiabetes MellitusDepression
Type 2 Diabetes MellitusConvulsionInsomniaDiabetes Mellitus Inadequate ControlWeight IncreasedHyperlipidaemiaPancreatitisAnxiety
Suicidal IdeationAnxietyAbdominal Pain UpperInsomniaHyperlipidaemiaNeuropathy PeripheralNeuropathy PeripheralNausea
Confusional StateSchizophreniaDiabetic KetoacidosisPancreatitisDiabetes Mellitus Inadequate ControlDiabetes Mellitus Inadequate ControlGastroenteritisSuicidal Ideation
Diabetes MellitusVomitingNeuropathy PeripheralBlood Cholesterol IncreasedNeuropathy PeripheralBack PainHyperglycaemiaHeadache
ConvulsionAgitationDiabetes Mellitus Inadequate ControlNeuropathy PeripheralInsomniaBlood Triglycerides IncreasedMood SwingsDrug Ineffective

Drug effectiveness by gender :

FemaleMale
Seroquel is effective44.78%
(90 of 201 people)
32.99%
(32 of 97 people)
Clonazepam is effective49.04%
(102 of 208 people)
43.69%
(45 of 103 people)

Most common drug interactions by gender * :

FemaleMale
Diabetes MellitusDiabetes Mellitus
Type 2 Diabetes MellitusType 2 Diabetes Mellitus
InsomniaWeight Increased
Weight IncreasedInsomnia
DepressionDepression
AnxietySuicidal Ideation
NauseaAnxiety
HeadacheHyperglycaemia
Suicidal IdeationDrug Ineffective
DizzinessPancreatitis

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Seroquel is effectiven/an/a20.00%
(2 of 10 people)
28.16%
(29 of 103 people)
18.34%
(31 of 169 people)
26.89%
(32 of 119 people)
23.66%
(22 of 93 people)
25.00%
(7 of 28 people)
Clonazepam is effectiven/an/a20.00%
(2 of 10 people)
29.91%
(32 of 107 people)
24.85%
(41 of 165 people)
31.15%
(38 of 122 people)
27.96%
(26 of 93 people)
28.57%
(8 of 28 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Diabetes MellitusTherapeutic Response Unexpected With Drug SubstitutionWeight IncreasedType 2 Diabetes MellitusType 2 Diabetes MellitusDiabetes MellitusDiabetes MellitusInsomnia
Weight IncreasedDrug IneffectiveSuicidal IdeationDiabetes MellitusDiabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusDepression
Type 2 Diabetes MellitusVision BlurredAggressionSuicidal IdeationDepressionWeight IncreasedInsomniaFatigue
PancreatitisDrug Effect DecreasedAgitationWeight IncreasedAnxietyInsomniaDepressionFall
Pulmonary HypertensionSuicide AttemptDepressionInsomniaWeight IncreasedPancreatitisWeight IncreasedDiabetes Mellitus
Drug Exposure During PregnancyComaAnxietyDyspnoeaHeadacheDepressionAnxietyConfusional State
Premature Rupture Of MembranesPupillary Reflex ImpairedType 2 Diabetes MellitusSuicide AttemptSuicidal IdeationDiabetic NeuropathyNauseaAnxiety
PregnancyParanoiaAbnormal BehaviourDizzinessDizzinessAnxietyPainNausea
GastritisDysarthriaSuicide AttemptHeadacheArthralgiaNeuropathy PeripheralNeuropathy PeripheralWeight Increased
Placenta PraeviaDroolingSomnolenceNauseaInsomniaBlood Cholesterol IncreasedSomnolenceDrug Ineffective

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Seroquel and Clonazepam?

You are not alone! Join a related mobile support group:
- support group for people who take Seroquel and Clonazepam
- support group for people who take Clonazepam
- support group for people who take Seroquel

Can you answer these questions (Ask a question):

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    25 year old client in early recovery from opioid dependence takes ritalin and seroquel and wants to add vivitrol. What are the risks and side effects?
  • Does anyone have experience of taking the supplement gaba with seroquel/quetiapine at night to aid sleep?. taking quetiapine 150 mg gives inconsistent sleep.
    With seroquel my sleep is inconsistent and if I have a bad night's sleep, I don't just feel tired, I feel breathless, headache, strange sensations, as if I haven't slept off side effects. It can make me feel relaxed when I take it but not sleepy.
  • Can my eye twitch be because of lexapro?
    So I have had symptoms of anxiety and depression due to a lot of stressors and disasters that happened in my life over the past two years. As my anxiety got worse after a breast biopsy, I started freaking out and thinking I may have MS because my sister has MS. So I went to my GP and she decided my symptoms do not follow the symptoms of MS or any similar problem and it should most likely be anxiety. She put me on Lexapro and Clonazepam. At first I was very hesitant to take medication but as my symptoms got worse I decided to give it a try. I was on Lexopro 5 mg for about two months and then I went to 10 mg, and I would take 1 or 2 Clonazepam a day. And this all started 5 months ago. And things seemed to be working just fine.Until about two months ago I started having this freaking annoying eye twitch on my upper left eyelid. I have had eye twitches before but they always go away after a couple of days or a week top. This one has been lasting for 2 months now and seems to be just getting worse. I went to the GP and my eye doctor and they still found no cause and said it's probably stress and anxiety. I have not been overly stressed and I get plenty of sleep, 10 hrs or more! and I stopped taking caffeine and alcohol after the twitch started. Any idea? Could it be because of medication? I also need to add I have had thumb twitching and severe spasms in my muscles around my right thumb starting in May (before taking any medication).

More questions for: Clonazepam, Seroquel

You may be interested at these reviews (Write a review):

  • A life of depression and fatigue
    1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
    do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Bipolar patient extremely violent on seraquel
    I have been diagnosed bipolar for over 10 years. 3 years ago I was taken off of topamax and my seraquel was upped to 300 mg from 100 because I was pregnant. I was very violent! Punching, breaking stuff, in jail, in the psych ward. Yes pregnancy and bipolar are not a perfect combination. I too thought it was the hormones. My husband and split several times over me punching him. We moved to a state cross country so there was no more family drama. Nothing worked! Over the last 3 years my life has been hell! I happen to run out of my seroquel (tg) it took 2 weeks to arrive. In that time my body went thru horrible withdrawals. I vowed I wouldn't take it any longer. I've been seraquel free for 2 months. I'm now on gabapentin and proud to say I have no anger issues! Not 1 punch has
    been thrown. I feel like a totally different person.
  • Seroquel and iron deficiency?
    I've been taking Seroquel for about four year, I have been having symptoms similar to hypothyroidism, and just found out I have an iron deficiency. The doctor said my platelets are smaller than average, and it is possible that my grandmother is anemic. But in trying to study Seroquel I kept finding things that made me wonder if Seroquel could be linked to iron deficiency.
  • Transition from mirtazapine to cymbalta (bipolar ii) 6 week duration taken in conjunction with seroquel, propranalol and implanon
    In early September I approached my Psychiatrist to report that I was having sleep paralysis episodes as well as insatiable appetite. I had put on about 20lb in the space of 6 months since the sleep paralysis started.

    My Psychiatrist opted to wean me off the Mirtazapine and onto Cymbalta. I have now been on 60mg of Cymbalta for about 4 weeks and completely titrated off the Mirtazapine.

    I have noted that since switching to Cymbalta that I no longer have the insatiable appetite, nor have I had any further sleep paralysis episodes (though I have had a brain MRI to rule out any physiological issues - yet to receive results).

    I have noticed that I have had mild to moderate rolling nausea with the Cymbalta and that I now have food aversions. Food does not interest me as much anymore and I find that certain foods (mostly processed snacks) are no longer palatable. I also find that I become full after much smaller meal portions.

    I have found that I can no longer drink wine or spirits because they now taste awful however I can still tolerate certain brands of beer. I also no longer enjoy drinking cola.

    I am also on the Implanon Implant. I have had this implant inserted for about 12 months and my cycles have been rather regular. Since starting the Cymbalta I have had some breakthrough bleeding yet my periods have not been as painful, though they have been heavier and longer.

    My Psychiatrist will commence titrating me off the Seroquel in about two weeks and onto Topamax as it is his belief it will be less sedating than the Seroquel and that it will hopefully help as a mood stabiliser, treat my migraines and allow me to come off the Propranolol. he also hopes that I am able to loose some of the weight gained since the sleep paralysis episodes started.

    As a side note regarding the Propranolol, I have naturally low blood pressure and I find while Propranalol is generally an effective migraine prophylactic, (I do get some breakthrough migraines) it does make my blood pressure even lower which leads to dizziness and faintness when I stand up too quickly from a recumbent position.

More reviews for: Clonazepam, Seroquel

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Complete drug side effects:

On eHealthMe, Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Clonazepam (clonazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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