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Review: Sertraline and Melatonin

This review analyzes the effectiveness and drug interactions between Sertraline and Melatonin. It is created by eHealthMe based on 154 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 4, 2014: 154 people who reported to have interactions when taking Sertraline, Melatonin are studied

Trend of Sertraline, Melatonin's drug interactions, side effects and effectiveness reports (4096282)

Drug combinations in study:
- Sertraline (sertraline hydrochloride)
- Melatonin (melatonin)

eHealthMe real world results:

Most common interactions experienced by people in the use of Sertraline, Melatonin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dizziness80
Pyrexia (fever)66
Gait Disturbance64
Anxiety62
Fatigue (feeling of tiredness)49
Headache (pain in head)42
Pain42
Hypoaesthesia (reduced sense of touch or sensation)40
Oedema Peripheral (superficial swelling)38
Tinnitus (a ringing in the ears)32

Most common interactions experienced by people in long term use of Sertraline, Melatonin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Fatigue (feeling of tiredness)7
Anxiety6
Hypomania (a mild form of mania, marked by elation and hyperactivity)4
Confusional State4
Disturbance In Attention4
Back Pain4
Feeling Abnormal4
Insomnia (sleeplessness)4
Headache (pain in head)4
Scoliosis (a medical condition in which a person's spine is curved from side to side)4

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Sertraline0.00%18.18%36.36%27.27%18.18%
Melatonin0.00%33.33%16.67%50.00%0.00%

Top conditions involved for these people * :

  1. Depression
  2. Insomnia
  3. Anxiety
  4. Pain
  5. Ill-defined disorder

Top co-used drugs for these people * :

  1. Zoloft
  2. Seroquel
  3. Aspirin
  4. Klonopin
  5. Multi-vitamins

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Related topic: Melatonin, Sertraline

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Complete drug side effects:

On eHealthMe, Sertraline (sertraline hydrochloride) is often used to treat depression. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (10 months ago):

  • Have had leaking right breast occasionally during peri-menopausal years. Just noticed same clear yellow liquid in same (right) breast. No pain, lumps, swelling, redness, etc., but the liquid is darker. Should I be concerned?

    Reply

  • From this study (10 months ago):

  • I have had occasional nipple discharge thru peri-menopausal years, always in my right breast only and always a yellowish clear color. I have not had a period in 7 months, so I'm pretty sure this is indicitive of full Menopause. I just noticed some leakage in same breast (right),still clear but a darker shade of yellow. There has never been any pain,lumps, swelling or redness, etc., involved. Should I be concerned about the color getting darker?

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

  • After being on zoloft (sertraline) for 19 years, i now notice multiple side effects and i want to get off
    I have been on Zoloft (sertraline) for 19 years for chronic depression. When I first started taking Zoloft, it made a huge positive impact on my life. It was a miracle drug for me. I believe it saved my life. Ten or so years ago it suddenly stopped working. My doctor had me try several other S ...

  • Does taking zoloft cause you to shoplift?
    Have been taking 200mg zoloft for anxiety/ depression for a few years now, anxiety is under control and depression but I am now shoplifting, my finances are okay ? I go into a trance and don't care and shoplift items I can afford and don't really need, I feel so bad after doing it, I don't have a cr ...

  • Is it safe to take pravastin while on remicade?
    I have just started on Remicade and this drug scares the heck out of me! However it is being used as a last resort as no other medications were bring my ulcerative colitis under control I am very concerned about drug interactions and can't seem to get any straight answers from my doctor or the pha ...

More questions for: Melatonin, Sertraline

You may be interested at these reviews (what is this?):

  • Melatonin and skin dryness
    I've been having hard time to sleep, so I started taking Melatonin. It is OTC sleep aid with melatonin and herbal treatment (lemon balm and camomile). about three days after started taking the drug, my back of hands started showing red rashes, then neck and around lips. a week after taking medica ...

  • Zoloft & klonipin created a horrible psychosis
    Causes psychosis, bipolar anxiety and seizures. Violence happens on all psychiatric drugs. Curing psychosis and deafness took the complete abandonment of psychiatry.

  • Steven-johnsons syndrome caused by zoloft
    Was diagnosed with depression start of last year due to my Aspergers multiplying school pressures for me. I was not put on any medication until 4 weeks ago. I was put on Zoloft 25mg, which slowly increased to 50mg. The moment I started on 50mg it caused severe lip dryness leading to cracking of the ...

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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