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Review: Sertraline and Melatonin

This review analyzes the effectiveness and drug interactions between Sertraline and Melatonin. It is created by eHealthMe based on reports of 186 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Sertraline and Melatonin >>>

What are the drugs

Sertraline (what 26,367 Sertraline users reported?) has active ingredients of sertraline hydrochloride. It is used in depression.

Melatonin (what 2,627 Melatonin users reported?) has active ingredients of melatonin. It is used in insomnia.

On Aug, 14, 2014: 186 people who take Sertraline, Melatonin are studied

Sertraline, Melatonin outcomes

Drug combinations in study:
- Sertraline (sertraline hydrochloride)
- Melatonin (melatonin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Sertraline is effective0.00%
(0 of 1 people)
0.00%
(0 of 4 people)
16.67%
(1 of 6 people)
25.00%
(2 of 8 people)
28.57%
(2 of 7 people)
40.00%
(2 of 5 people)
33.33%
(2 of 6 people)
50.00%
(1 of 2 people)
Melatonin is effective16.67%
(1 of 6 people)
57.14%
(4 of 7 people)
12.50%
(1 of 8 people)
33.33%
(2 of 6 people)
55.56%
(5 of 9 people)
50.00%
(1 of 2 people)
0.00%
(0 of 1 people)
0.00%
(0 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DizzinessFatigueHallucination, VisualRapid Eye Movements Sleep AbnormalHeadacheFeeling AbnormalDiarrhoeaDizziness
Paraesthesia OralDrug IneffectiveFasciculations Of MusclePostural Orthostatic Tachycardia SyndromeDermatillomaniaFatigueGait Disturbance
TinnitusIntentional Self-injuryTremorLightheadedness - FaintingBack Pain - LowConfusional StatePyrexia
Gait DisturbanceRestless Legs SyndromeRapid Eye Movements Sleep AbnormalTremorFear, FocusInsomniaAnxiety
Feeling DrunkInsomniaHallucinations AggravatedFasciculations Of MuscleTirednessHeadacheOedema Peripheral
HypoaesthesiaAkathisiaTirednessHallucinations AggravatedPain - BackNightmarePain
SyncopeSomnolenceDermatillomaniaHallucination, VisualNipple Discharge - AbnormalMuscle SpasmsConstipation
Neurological Examination AbnormalRestlessnessFear, FocusPelvic PainFatigueMuscle TwitchingHypophagia
Confusional StateDependencePain - BackBack PainAbdominal PainNervousnessFatigue
IncontinenceAgitationHypomaniaPainEmotional Distress

Drug effectiveness by gender :

FemaleMale
Sertraline is effective26.92%
(7 of 26 people)
23.08%
(3 of 13 people)
Melatonin is effective34.62%
(9 of 26 people)
35.71%
(5 of 14 people)

Most common drug interactions by gender * :

FemaleMale
DizzinessMultiple Drug Overdose
Gait DisturbanceBrain Oedema
PyrexiaPulmonary Oedema
Oedema PeripheralDizziness
Confusional StateFall
AnxietyAnxiety
PainMuscle Twitching
HypophagiaDrug Abuse
ConstipationRestless Legs Syndrome
DeathFatigue

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Sertraline is effectiven/a0.00%
(0 of 2 people)
20.00%
(1 of 5 people)
20.00%
(3 of 15 people)
18.18%
(2 of 11 people)
12.50%
(1 of 8 people)
25.00%
(2 of 8 people)
20.00%
(1 of 5 people)
Melatonin is effectiven/a0.00%
(0 of 2 people)
16.67%
(1 of 6 people)
14.29%
(2 of 14 people)
50.00%
(5 of 10 people)
0.00%
(0 of 9 people)
37.50%
(3 of 8 people)
42.86%
(3 of 7 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aMuscle TwitchingDizzinessPulmonary OedemaPain In ExtremityFatigueIncontinencePyrexia
DyskinesiaGait DisturbanceBrain OedemaChest PainDrug IneffectiveLethargyAnxiety
Muscular WeaknessParaesthesia OralHypotensionHeadacheInsomniaConfusional StatePain
CoughFeeling DrunkHypothyroidismMyalgiaDysuriaAccidental ExposureDeep Vein Thrombosis
HypoprolactinaemiaTinnitusLymphopeniaSwelling FaceDepressionUnresponsive To StimuliHeart Rate Increased
HaemorrhageHypoaesthesiaNeutropeniaMyocardial InfarctionFeeling AbnormalSomnolenceDizziness
FallSyncopeHyponatraemiaJoint SwellingConfusional StateDrug IneffectiveThroat Irritation
PresyncopeMultiple Drug OverdoseHypocalcaemiaOedema PeripheralIrritabilityHeadacheConstipation
Joint InjuryNeurological Examination AbnormalDiarrhoeaManiaSuicidal IdeationFatigueHypophagia
ParaesthesiaVertigoDiplopiaMuscle SpasmsSedationDepressed Level Of ConsciousnessEmotional Distress

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group of people like you:
- group for people who take Sertraline and Melatonin
- group for people who take Melatonin
- group for people who take Sertraline

Comments from related studies:

  • From this study (3 weeks ago):

  • Upon taking the Clonidine & melatonin before bedtime, this 4 year old develops severe knee clicking which seems to hurt her upon falling asleep. If she gets angry during the day she can involuntarily start the knee clicking. She is very double jointed.

    Reply

  • From this study (1 year ago):

  • Have had leaking right breast occasionally during peri-menopausal years. Just noticed same clear yellow liquid in same (right) breast. No pain, lumps, swelling, redness, etc., but the liquid is darker. Should I be concerned?

    Reply

  • From this study (1 year ago):

  • I have had occasional nipple discharge thru peri-menopausal years, always in my right breast only and always a yellowish clear color. I have not had a period in 7 months, so I'm pretty sure this is indicitive of full Menopause. I just noticed some leakage in same breast (right),still clear but a darker shade of yellow. There has never been any pain,lumps, swelling or redness, etc., involved. Should I be concerned about the color getting darker?

    Reply

Post a new comment    OR    Read more comments

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Complete drug side effects:

On eHealthMe, Sertraline (sertraline hydrochloride) is often used to treat depression. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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