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Review: taking Sinemet and Loperamide together

Summary: drug interactions are reported among people who take Sinemet and Loperamide together.

This review analyzes the effectiveness and drug interactions between Sinemet and Loperamide. It is created by eHealthMe based on reports of 76 people who take the same drugs from FDA and social media, and is updated regularly.


You are not alone: join a support group for people who take Sinemet and Loperamide >>>

On Apr, 21, 2015: 76 people who take Sinemet, Loperamide Hydrochloride are studied

Sinemet, Loperamide Hydrochloride outcomes

Drug combinations in study:
- Sinemet (carbidopa; levodopa)
- Loperamide Hydrochloride (loperamide hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Sinemet is effectiven/an/a100.00%
(1 of 1 people)
(1 of 1 people)
Loperamide Hydrochloride is effectiven/an/an/a0.00%
(0 of 1 people)
(0 of 1 people)

Drug effectiveness by gender :

Sinemet is effectiven/a100.00%
(2 of 2 people)
Loperamide Hydrochloride is effectiven/a0.00%
(0 of 2 people)

Drug effectiveness by age :

Sinemet is effectiven/an/an/an/an/an/an/a100.00%
(2 of 2 people)
Loperamide Hydrochloride is effectiven/an/an/an/an/an/an/a0.00%
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Speech Disordern/an/an/an/an/an/aMuscle Spasms
Diabetic NephropathyCholestasis
DiarrhoeaCytolytic Hepatitis
Bacterial Test PositiveNeck Pain
Eosinophil Count IncreasedCondition Aggravated
RetinopathyPulmonary Embolism
Neuropathy PeripheralIntestinal Obstruction

Most common drug interactions by gender * :

CholestasisMuscle Spasms
Cytolytic HepatitisNeck Pain
DiarrhoeaPulmonary Embolism
FlushingIntestinal Obstruction
Carcinoid Tumour Of The Small BowelGait Disturbance
Haemoglobin DecreasedGastrointestinal Haemorrhage
Catheter Related InfectionBack Pain
Laboratory Test AbnormalDecreased Appetite

Most common drug interactions by age * :

n/an/an/an/an/aBone InfectionOedema Lower LimbPyrexia
Pneumonia NosMyalgiaPulmonary Embolism
Condition AggravatedPneumonia NosDiarrhoea
Sepsis NosSepsis NosIntestinal Obstruction
Back PainTachycardia NosMuscle Spasms
Headache NosSinusitis NosNausea
Muscle SpasmsMuscle SpasmsTremor
Neck PainNeck PainAsthenia
Catheter Related InfectionDyspnoea NosGait Disturbance
MyalgiaCondition AggravatedGastrointestinal Haemorrhage

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Sinemet and Loperamide on

Do you take Sinemet and Loperamide?




You are not alone! Join a related support group:
- support group for people who take Loperamide Hydrochloride
- support group for people who take Sinemet

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Sinemet (carbidopa; levodopa) is often used to treat parkinson's disease. Loperamide Hydrochloride (loperamide hydrochloride) is often used to treat diarrhea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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