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Review: taking Sonata and Phenergan together

Summary: drug interactions are reported among people who take Sonata and Phenergan together.

This review analyzes the effectiveness and drug interactions between Sonata and Phenergan. It is created by eHealthMe based on reports of 86 people who take the same drugs from FDA and social media, and is updated regularly.


You are not alone: join a support group for people who take Sonata and Phenergan >>>

On Mar, 31, 2015: 86 people who take Sonata, Phenergan are studied

Sonata, Phenergan outcomes

Drug combinations in study:
- Sonata (zaleplon)
- Phenergan (promethazine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Sonata is effectiven/an/an/an/an/a0.00%
(0 of 1 people)
Phenergan is effectiven/an/an/an/a100.00%
(1 of 1 people)

Drug effectiveness by gender :

Sonata is effective0.00%
(0 of 1 people)
Phenergan is effective100.00%
(1 of 1 people)

Drug effectiveness by age :

Sonata is effectiven/an/an/an/an/a0.00%
(0 of 2 people)
Phenergan is effectiven/an/an/an/an/a50.00%
(1 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Vomiting Nosn/aVentricular Septal Defectn/aErection ProblemsErection Problemsn/aPain
DisorientationDrug Exposure During PregnancySkin StriaeSkin StriaeAnxiety
ConfusionAtrial Septal DefectDrug Exposure During Pregnancy
Foetal Distress SyndromeVentricular Septal Defect
Respiratory DistressAnaemia
ApnoeaAtrial Septal Defect
Aortic DisorderRespiratory Distress
Post Procedural ComplicationFoetal Distress Syndrome
Fallot's TetralogyApnoea

Most common drug interactions by gender * :

Drug Exposure During PregnancyDrug Ineffective
Ventricular Septal DefectMigraine
Atrial Septal DefectMyocardial Infarction
AnaemiaAspartate Aminotransferase Increased
ApnoeaDrug Dependence
Respiratory DistressDyspnoea
Foetal Distress SyndromeChest Pain

Most common drug interactions by age * :

n/an/an/an/aDepressionArthralgiaPancreatic Duct StenosisMyocardial Infarction
HypothyroidismChest PainHepatic CirrhosisIntestinal Stenosis
ConvulsionFallBile Duct StenosisAnastomotic Complication
InsomniaFatigueChronic HepatitisPain In Extremity
Loss Of ConsciousnessDrug IneffectiveSphincter Of Oddi DysfunctionAbdominal Pain
IrritabilityDrug Withdrawal SyndromeConvulsionAspartate Aminotransferase Increased
Gastrooesophageal Reflux DiseaseDiabetes MellitusBlood Pressure IncreasedRectal Haemorrhage
Drug AbuserMuscle SpasmsPortal Vein PhlebitisFatigue
DysarthriaPainFlank PainDrug Hypersensitivity
HypoaesthesiaOedema PeripheralHepatic SteatosisOverdose

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Sonata and Phenergan?




You are not alone! Join a related support group:
- support group for people who take Phenergan
- support group for people who take Sonata

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Sonata (zaleplon) is often used to treat insomnia. Phenergan (promethazine hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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