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Review: Suboxone and Benadryl





Summary: drug interactions are reported among people who take Suboxone and Benadryl together.

This review analyzes the effectiveness and drug interactions between Suboxone and Benadryl. It is created by eHealthMe based on reports of 61 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Suboxone and Benadryl >>>

What are the drugs

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. (latest outcomes from Suboxone 8,267 users)

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (view latest outcomes from 29,367 users)

On Nov, 25, 2014: 61 people who take Suboxone, Benadryl are studied

Suboxone, Benadryl outcomes

Drug combinations in study:
- Suboxone (buprenorphine hydrochloride; naloxone hydrochloride)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Suboxone is effective0.00%
(0 of 3 people)
100.00%
(1 of 1 people)
100.00%
(3 of 3 people)
0.00%
(0 of 1 people)
n/an/an/a100.00%
(2 of 2 people)
Benadryl is effective0.00%
(0 of 2 people)
0.00%
(0 of 2 people)
n/a50.00%
(1 of 2 people)
0.00%
(0 of 1 people)
n/a0.00%
(0 of 1 people)
100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
VomitingSuicidal IdeationOil AcneInsomniaConfusionn/an/aInsomnia
Respiratory Tract InfectionDrug Withdrawal SyndromeNight SweatsVomitingLoss Of Consciousness
PyrexiaFrustrationDrowsinessAgitationFatigue
Septic ShockPlacenta PraeviaNauseaTongue DiscolourationWeight Increased
PneumoniaFatigueVertigoThrombosisOedema Peripheral
Stress FractureAstheniaDepressionConstipation
Visual Acuity ReducedMalaiseEuphoric MoodDrug Withdrawal Syndrome
Tongue DiscolourationMaternal Exposure During PregnancyWeight IncreasedDepression
Pharyngitis StreptococcalDrowsinessToothacheVomiting
ThrombosisOil AcneLoss Of ConsciousnessBack Pain

Drug effectiveness by gender :

FemaleMale
Suboxone is effective75.00%
(3 of 4 people)
50.00%
(3 of 6 people)
Benadryl is effective25.00%
(1 of 4 people)
20.00%
(1 of 5 people)

Most common drug interactions by gender * :

FemaleMale
VomitingInsomnia
DepressionFluid Retention
InsomniaFatigue
Loss Of ConsciousnessDecreased Interest
FatigueCardiovascular Disorder
Euphoric MoodDrug Withdrawal Syndrome
Weight IncreasedJoint Swelling
ToothacheWeight Increased
PainOedema Peripheral
NauseaMemory Impairment

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Suboxone is effectiven/an/a33.33%
(1 of 3 people)
45.45%
(5 of 11 people)
0.00%
(0 of 2 people)
n/a0.00%
(0 of 1 people)
n/a
Benadryl is effectiven/an/a0.00%
(0 of 3 people)
12.50%
(1 of 8 people)
50.00%
(1 of 2 people)
n/a0.00%
(0 of 1 people)
n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aDrowsinessLactic AcidosisLoss Of ConsciousnessInsomniaDrug Withdrawal SyndromeStress Fracture
NauseaMalaiseDepressionFluid RetentionSuicidal IdeationAgitation
VertigoDiabetes MellitusEuphoric MoodOedema PeripheralFrustrationRespiratory Tract Infection
Gastrooesophageal Reflux DiseaseInsomniaBack PainConjunctivitisThrombosis
Mouth UlcerationWeight IncreasedFatigueCellulitisTongue Discolouration
Pulmonary EmbolismToothacheMemory ImpairmentVomiting
Chest PainFatigueWeight IncreasedVisual Acuity Reduced
PainConstipationCardiovascular DisorderPyrexia
AtaxiaDrug Screen PositiveConstipationSeptic Shock
DysarthriaHyperhidrosisDrug Withdrawal SyndromeCerebrovascular Accident

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Suboxone and Benadryl?

You are not alone! Join a related mobile support group:
- support group for people who take Suboxone and Benadryl
- support group for people who take Benadryl
- support group for people who take Suboxone

Can you answer these questions (Ask a question):

More questions for: Benadryl, Suboxone

You may be interested at these reviews (Write a review):

  • Suboxone treatment may have caused my trichotillomania
    It's a long story of how I became addicted to opiates after 15+ years of chronic pain, but I decided to give up pain killers and try suboxone/subutex treatment. Shortly thereafter, I began pulling hair. First from my head, then when the bald spots became too obvious I started pulling from all over. It seemed to be triggered by stress or anxiety but not always. I did not make an association until recently, when I finally stopped the suboxone. It was two weeks of miserable withdrawal, much worse than from pain killers themselves, but I am finally out of the haze I'd be in all of that time, and I have no urge to pull hair whatsoever. I don't know how often the association of suboxone use and trichotillomania has been examined, but I wanted to share my experience in case anyone else is in a similar situation. Also, if you are considering starting suboxone treatment, don't. Withdrawal from opiates will lead to a few pretty rough days, but that's nothing compared to what you'll go through during suboxone withdrawal.
  • Dyphenhydramine and headaches horrible going one almost 24 hours a day for 4 weeks and cant get them to stop, now looking for cause . think its the dyphenhydramine im taking to help me sleep .
    have been taking 3 dyphenhydramine for some time to help me sleep , just in last few weeks began having severe headache almost all the time.. cant get it to go away. just found out it can cause headache and am going to lower my intake to one per night and see if my headaches get better. am taking migrane meds and that hasnt helped a bit so think its not migranes im having. some other reason.
  • Pacemaker experience
    I had a pacemaker installed about 5 weeks ago. I went to the doctors because I was feeling fatigue, shortness of breath, I felt as if someone was holding my heart in their hand and I had some confusion and dizziness.

    To get to the point, after my first visit with my PCP I decided to go directly to emergency via 911 since my PCP was basically ignoring, or better put, had no sense of urgency regarding how I was feeling even though she knew my heart rate had dropped and was steady at 44 bpm, my normal rate 62 bpm.

    The night I was in observation at the hospital I dropped to 20 bpm, next day I had a pacemaker installed, had I not taken the initiative to call the hospital I don't know if I would have continued dropping until I was dead, I don't know enough about the science behind this to draw that conclusion but common sense tells me yes.

    I have explained this in another post but I cannot find it, not sure what I am doing wrong, so I am writing another post because I have more to add after a couple of weeks since my last post.

    The issue I have is I am still tired after more than a month after the installation of the pacemaker. I had the bpm (beats per minute) on my pacemaker increased from 60, the factory settings, to somewhere in the mid 60's.......so I thought. I went to the hospital twice to have my pacemaker "tweaked" but when I met with the cardiologist for my "one week" follow up, which took almost three weeks to see him due to his heavy schedule, he told me there were never any changes made to my pacemaker, I was still at 60 bpm. How could this be since I was told twice it had been increased? I had the wand on my chest and the nurse made the changes which were made due to my complaining about being exhausted still, the reason I went to the PCP in the first place five weeks ago.
    Was she playing mind games, thinking the power of suggestion would make me feel better? If so I am disgusted to think she would feel I was faking my feelings of exhaustion, what she did had absolutely no effect on how poorly I was feeling.

    To get to the point, I finally had my first meeting with the surgeon, he raised my bpm to 75 from 60, was going to go to 80 but changed his mind. The moment he made the change to 75 bpm from my original 60 he asked if I was feeling better, feeling better after 60 seconds of changing the bpm, how is that possible? I told him no, kind of too soon to tell. His reply was "it looks like we have done everything we can on our end, your heart was not significantly damaged, your pacemaker is working as it should, therefore there must be something else making you feel so poorly so I suggest you see an internal medicine specialist." My brain had a big WHAT sign flashing, I couldn't believe what he was saying, basically beat it and move on, I don't have the time to deal with you anymore. Lets see, the appointment lasted 25 minutes and he does not have the time to work with me anymore, sorry but that irritates the hell out of me.

    He was washing his hands of me, nothing else he could do so spend time and money finding out what the problem is with an internest, it is not my heart according to the cardiologist. The appointment ended and I left wondering how I was going to find out what is causing my issues.

    To my great fortune a nurse with 20 years experience teaching doctors and nurses how to use the pacemaker computer asked me to come into her office after my appointment with the cardiologist, she asked me this prior to seeing the doctor. Thank God she did as the doctor did not do a thorough job adjusting the pacemaker, she adjusted what the doctor had, tweaked the pacemaker a bit, had me walk for 10 minutes and come back to the office and did a bit more tweaking, I slowly started feeling a touch better. She asked me to come back in two weeks and she would see if the pacemaker needed to be tweaked a bit more. I was walking on air, still not close to my "normal", thrilled I was not just a number being tossed in the heap of unfixed people. I am feeling 70% better than how I felt prior to the doctor and her tweaking the pacemaker. Had she not been there that day and had the opportunity to do this I would be on a never ending search for what is making me feel so exhausted and!
    dizzy.

    There is a moral to this which I will let you draw your own conclusion. In my mind it is trust God will intervene, he certainly did when the nurse asked me to see her after the appointment with the surgeon. The reason I feel this way is because she was there and is only there on Fridays, the day I had my appointment. I never would have gone back again after my meeting with the doctor and I would have been spending needless hours and money looking through the wrong box for what ales me. Now it is obvious it was my pacemaker settings, my heart rate was set too low and the pacemaker was not fine tuned properly with the proper slope and other settings.

    Don't let these doctors do what mine tried doing with me, be aggressive and insist on more adjustments if you have issues similar to mine.

    AS I sit here I am still tired, I could easily take a nap but I am better than I was yesterday, significantly.

    Best of luck to all. Your comments will be very much appreciated.
  • Nightmare on benadryl
    After 5 nights without sleep and not having past bad dreams, the last 2 night's taking walfrin sub, for benadryl has terrified THE WORST OF WORST dream in my 55 years. Peaceful start of a dream then seeing myself or family,friends get slottard.crazy thing is I don't watch scary movies or the news. I think I'm going to pass on this meds, and pass out next time :) thank you,God bless
  • Benadryl completed suicide 50 year old
    My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.

More reviews for: Benadryl, Suboxone

Comments from related studies:

  • From this study (9 months ago):

  • Been I'll for 9 months. Just recently found pneumonia. Can't afford dermatologist and do for doesn't know what the hives are. You can write with your finger on my skin and it will show up.

    Reply

  • From this study (3 years ago):

  • i started taking suboxone so i could get off pain pills, had been using 300mg of oxycotton. I started taking dramaene because i would get car sick, and the allergy meds because of seasonal allergys. it also makes me kinda sleepy/out of it.

    Reply

Complete drug side effects:

On eHealthMe, Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat opiate withdrawal. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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