Review: Suboxone and Depakote drug interactions
This review analyzes the interactions between Suboxone and Depakote. It is created by eHealthMe based on 39 people who have drug interactions while taking the drugs. The review uses reports from FDA and social media, and is updated regularly.
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What are the drugs
Suboxone (latest outcomes from 8,150 users) has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal.
Depakote (latest outcomes from 30,846 users) has active ingredients of divalproex sodium. It is often used in bipolar disorder.
On Mar, 8, 2014: 39 people who reported to have interactions when taking Suboxone, Depakote are studied
Drug combinations in study:
- Suboxone (buprenorphine hydrochloride; naloxone hydrochloride)
- Depakote (divalproex sodium)
Most common interactions experienced by people in the use of Suboxone, Depakote:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)||14|
|Intentional Drug Misuse||11|
|Nausea (feeling of having an urge to vomit)||9|
|Pericardial Effusion (fluid around the heart)||9|
|Bipolar Disorder (mood disorder)||9|
|Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)||9|
Most common interactions experienced by people in long term use of Suboxone, Depakote:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Frequent Headaches (pain in head)||2|
|Oxygen Saturation Decreased||2|
|Intentional Drug Misuse||2|
|Pulmonary Oedema (fluid accumulation in the lungs)||2|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
- Bipolar disorder
- Drug dependence
Top co-used drugs for these people * :
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat opiate withdrawal. Depakote (divalproex sodium) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Suboxone is used in:
- Depakote is used in:
Other drugs that are used to treat the same conditions:
- Suboxone alternatives:
- Depakote alternatives:
Comments from related studies:
From this study (2 years ago):
From this study (4 years ago):
I want to know if it's safe to add the lidocaine patch with my other medications and I also want to know if I can use one on elbow and one on back at the same time.
Suboxone is a miracle drug for opiate addiction, (taken as prescribed and along with other forms of tx. Sort of like you need to eat healthy, work out, ect. to really feel effects if you want to get in shape. Of course, the road to recovery is much harder than example, at least for me anyway:). Depakote has helped w/ my anxiety, if only I could get past the drowsiness. I also feel that since getting back on the depakote, that it may be over-riding the adderall? Anyone else experience this?
Can you answer these questions (what is this?):
- By D.S.B.: Has long term clonazepam use caused you seemingly irreversible psychosis, for which you were given an antipsychotic? if so, were you able to get off of the antipsychotic and clonazepam? how?
Started clonazepam around 2002. In 2007, I was hospitalized (I'm not sure what the doctors were thinking) and I was given an antipsychotic as well, and maybe another medication. My psychiatrist lowered and eliminated all my medication in 2011 and 2012, and each time was hospitalized and again given ...
- By Tyfniedawn: Hydroxyzine and suboxone is it safe together?? almost at my 6 month mark of this pregnancy!
I'm almost 6 months pregnant. The doctor started me on 25mg of hydroxyzine 1 or 2 for anxiety and 1 or 2 at bed. I've just been taking 3 an hour or so before bed. Today he started me on 1 mg of Suboxone a day. Is my 3 an evening still going to be safe because it's helped tremendously with making up ...
- By tlcfisher: What would cause a false positive for valium? i.e. i didnt take it, but has shown up in several of my urine test
I've been going to my Suboxone doctor for over a year now. In that time all I have done (as far as "narcotic" go) is my Suboxone and when my grandpa passed she wrote me a small script, on 2 different occasion for Xanax 0.5 (which I was actually able to hold onto until about a month ago..) Well, yest ...
You may be interested at these reviews (what is this?):
- By LauraInArizona: Depakote er affected by grapefruit
I have taken Depakote ER for since 2005 for epilepsy. Once stabilized many years ago seizures and auras have not been bothering me. Until I recently ate three grapefruits over three days. After a few days, when the grapefruit cleared my system, the seizures and auras ceased. Therefore, grapefrui ...
- By Cococounty925530: Thinking about methadone maintenance? don't do it
I'm on Methadone Maintenance Therapy (MMT) after failing to stay off of chronic and illicit use of heroin, dilaudid, and methamphetamines. I tried going clean using the subutex/ suboxone method twice and wasn't able to stop using the other drugs. With MMT I am clean of the illicit drugs, but I ...
- By Eric: Generic suboxone causing heart palpitations
I've been on the name brand Suboxone and recently was changed over to a generic Bupe/Naloxone and started having an extreme amount of heart palpitations three days after the switch. They began mildly and by the third day had increased to the point I had to stop taking it. Once I started taking the n ...
Recent related drug studies:
- A study of drug interactions between Depakote Er, Suboxone for a patient with Anxiety Disorder, Pain Management. The patient has Fecal Incontinence (Bowel incontinence)
- A study of drug interactions between Depakote Er, Ritalin, Zoloft, Remeron, Suboxone for a patient with Bipolar 2, Atypical Attention Deficit Syndrome, Adjustment Disorder With Mixed Anxiety And Depressed Mood, Sleeping Difficulty, Alcohol Rehabilitation. The patient has Lidocaine - 5%
- A study of drug interactions between Depakote Er, Adderall 30, Lexapro, Suboxone for a patient with Anxiety, Add, Depression, Addiction.
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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