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Review: Suboxone and Promethazine





Summary: drug interactions are reported among people who take Suboxone and Promethazine together.

This review analyzes the effectiveness and drug interactions between Suboxone and Promethazine. It is created by eHealthMe based on reports of 56 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Suboxone and Promethazine >>>

What are the drugs

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. (latest outcomes from Suboxone 8,267 users)

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. (view latest outcomes from 1,213 users)

On Nov, 24, 2014: 56 people who take Suboxone, Promethazine are studied

Suboxone, Promethazine outcomes

Drug combinations in study:
- Suboxone (buprenorphine hydrochloride; naloxone hydrochloride)
- Promethazine (promethazine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Suboxone is effective80.00%
(4 of 5 people)
100.00%
(2 of 2 people)
0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
100.00%
(1 of 1 people)
n/an/a50.00%
(1 of 2 people)
Promethazine is effective25.00%
(1 of 4 people)
66.67%
(2 of 3 people)
n/a0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
n/an/a100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
InsomniaEndocarditisFoetal Exposure During Pregnancyn/an/an/an/aVomiting
HallucinationRenal InfarctPremature BabyDehydration
Gun Shot WoundSweating FeverSweating FeverRenal Failure
Respiratory DepressionClamminessClamminessSomnolence
ItchingChest PainNausea
Decreased AppetitePancreatitis
Pancreatitis Acute
Maternal Exposure During Pregnancy
Mania
Lethargy

Drug effectiveness by gender :

FemaleMale
Suboxone is effective25.00%
(1 of 4 people)
100.00%
(8 of 8 people)
Promethazine is effective66.67%
(2 of 3 people)
42.86%
(3 of 7 people)

Most common drug interactions by gender * :

FemaleMale
VomitingEndocarditis
DehydrationInsomnia
Renal FailureRenal Infarct
SomnolenceDrug Toxicity
NauseaHallucination
Pancreatitis AcuteAccidental Drug Intake By Child
Confusional StatePneumothorax
Weight DecreasedDrug Withdrawal Syndrome Neonatal
MalaiseFoetal Exposure During Pregnancy
ManiaGun Shot Wound

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Suboxone is effectiven/an/a66.67%
(2 of 3 people)
60.00%
(3 of 5 people)
100.00%
(1 of 1 people)
60.00%
(3 of 5 people)
0.00%
(0 of 1 people)
n/a
Promethazine is effectiven/an/a66.67%
(2 of 3 people)
0.00%
(0 of 4 people)
100.00%
(1 of 1 people)
25.00%
(1 of 4 people)
100.00%
(1 of 1 people)
n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aAccidental Drug Intake By ChildChest PainPancreatitis Acuten/aDehydrationEscherichia Infectionn/a
Drug ToxicityNauseaSomnolenceClostridium Difficile Colitis
Vomiting NosPancreatitisRenal FailureListeriosis
SedationAdverse Drug ReactionHyporesponsive To StimuliGastroenteritis Viral
Drug MaladministrationRenal InfarctManiaVomiting
EndocarditisConfusional StateDehydration
InsomniaLethargyInjection Site Haematoma
VomitingRespiratory DepressionProductive Cough
Placenta PraeviaClamminessNasal Congestion
Maternal Exposure During PregnancySweating FeverDiarrhoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Suboxone and Promethazine?

You are not alone! Join a related mobile support group:
- support group for people who take Suboxone and Promethazine
- support group for people who take Promethazine
- support group for people who take Suboxone

Can you answer these questions (Ask a question):

More questions for: Promethazine, Suboxone

You may be interested at these reviews (Write a review):

  • Pacemaker experience
    I had a pacemaker installed about 5 weeks ago. I went to the doctors because I was feeling fatigue, shortness of breath, I felt as if someone was holding my heart in their hand and I had some confusion and dizziness.

    To get to the point, after my first visit with my PCP I decided to go directly to emergency via 911 since my PCP was basically ignoring, or better put, had no sense of urgency regarding how I was feeling even though she knew my heart rate had dropped and was steady at 44 bpm, my normal rate 62 bpm.

    The night I was in observation at the hospital I dropped to 20 bpm, next day I had a pacemaker installed, had I not taken the initiative to call the hospital I don't know if I would have continued dropping until I was dead, I don't know enough about the science behind this to draw that conclusion but common sense tells me yes.

    I have explained this in another post but I cannot find it, not sure what I am doing wrong, so I am writing another post because I have more to add after a couple of weeks since my last post.

    The issue I have is I am still tired after more than a month after the installation of the pacemaker. I had the bpm (beats per minute) on my pacemaker increased from 60, the factory settings, to somewhere in the mid 60's.......so I thought. I went to the hospital twice to have my pacemaker "tweaked" but when I met with the cardiologist for my "one week" follow up, which took almost three weeks to see him due to his heavy schedule, he told me there were never any changes made to my pacemaker, I was still at 60 bpm. How could this be since I was told twice it had been increased? I had the wand on my chest and the nurse made the changes which were made due to my complaining about being exhausted still, the reason I went to the PCP in the first place five weeks ago.
    Was she playing mind games, thinking the power of suggestion would make me feel better? If so I am disgusted to think she would feel I was faking my feelings of exhaustion, what she did had absolutely no effect on how poorly I was feeling.

    To get to the point, I finally had my first meeting with the surgeon, he raised my bpm to 75 from 60, was going to go to 80 but changed his mind. The moment he made the change to 75 bpm from my original 60 he asked if I was feeling better, feeling better after 60 seconds of changing the bpm, how is that possible? I told him no, kind of too soon to tell. His reply was "it looks like we have done everything we can on our end, your heart was not significantly damaged, your pacemaker is working as it should, therefore there must be something else making you feel so poorly so I suggest you see an internal medicine specialist." My brain had a big WHAT sign flashing, I couldn't believe what he was saying, basically beat it and move on, I don't have the time to deal with you anymore. Lets see, the appointment lasted 25 minutes and he does not have the time to work with me anymore, sorry but that irritates the hell out of me.

    He was washing his hands of me, nothing else he could do so spend time and money finding out what the problem is with an internest, it is not my heart according to the cardiologist. The appointment ended and I left wondering how I was going to find out what is causing my issues.

    To my great fortune a nurse with 20 years experience teaching doctors and nurses how to use the pacemaker computer asked me to come into her office after my appointment with the cardiologist, she asked me this prior to seeing the doctor. Thank God she did as the doctor did not do a thorough job adjusting the pacemaker, she adjusted what the doctor had, tweaked the pacemaker a bit, had me walk for 10 minutes and come back to the office and did a bit more tweaking, I slowly started feeling a touch better. She asked me to come back in two weeks and she would see if the pacemaker needed to be tweaked a bit more. I was walking on air, still not close to my "normal", thrilled I was not just a number being tossed in the heap of unfixed people. I am feeling 70% better than how I felt prior to the doctor and her tweaking the pacemaker. Had she not been there that day and had the opportunity to do this I would be on a never ending search for what is making me feel so exhausted and!
    dizzy.

    There is a moral to this which I will let you draw your own conclusion. In my mind it is trust God will intervene, he certainly did when the nurse asked me to see her after the appointment with the surgeon. The reason I feel this way is because she was there and is only there on Fridays, the day I had my appointment. I never would have gone back again after my meeting with the doctor and I would have been spending needless hours and money looking through the wrong box for what ales me. Now it is obvious it was my pacemaker settings, my heart rate was set too low and the pacemaker was not fine tuned properly with the proper slope and other settings.

    Don't let these doctors do what mine tried doing with me, be aggressive and insist on more adjustments if you have issues similar to mine.

    AS I sit here I am still tired, I could easily take a nap but I am better than I was yesterday, significantly.

    Best of luck to all. Your comments will be very much appreciated.
  • Yawning after taking sub
    Within a few minutes after I take my Suboxone film I seem to get intense yawning event along with runny nose & watery eyes lasting 5-15 mins. Sometimes I can make it subside by drinking a lot of water if I am in a place I can get it. I have been on Sub for approx 5 yrs. & have only noticed this side effect during the past 1 yr or so. It doesn't seem to matter if I take 1/2 or a whole film, (4mg or 8mg.)
    While this isn't life shattering it can be quite annoying if I am out in public, at work, etc. The yawning gets so intense at times I feel like my jaw will unhinge & can't control it at all.
    It seems paradoxical to me. Previously taking Sub would stop any typical opiate withdrawal symptoms such a yawing & runny nose & eyes. Now it actually causes this effect. I don't get any other feelings of going into withdrawal. Just those I mentioned. Could it be a reaction to the naloxone?
  • Insomnia from suboxone (1 response)
    Does Suboxone cause insomnia? Hell yes, I haven't slept properly for years and I wish I had never gone on it. My night is my day and daybreak is when i'm heading off to sleep,I try to wake up about 11 am but that is still half the day gone. I am so so over it, all I can do is reduce my dose

    and that's what I am doing. :(
  • Fibromyalgia & related health issues (3 responses)
    Fibromyalgia dx after pregnancy of only child at 42/other dx followed and seem to be in conjunction. heart issues did not appear until after the use of fibro meds- cymbalta, lyrica, neurontin, and more. had 1 seizure believed to be related to seretonin syndrome/years and years of mistreatment by doctors. unable to recall how many docs and meds through the years. one other very significant issue- after tooth extraction had puncture to left maxillary sinus-after YEARS of neglect by docs, found max. & ethmoid sinus completely opaque on CAT scan. Had surgery. Now, years later, have mucous plug that sporadically comes out upon sneezing. Fairly recent CAT scan shows sinuses again completely opaque. Certain needs further attention, but basically afraid to go through surgery again. Also- may have had heart attack. ER visit said no, but shortly after, had abnormal ekg. Again, neglect from docs. Am now active advocate for fm/chronic pain patients. Disgusted by the whole lack of interest of medical community. Looking for answers through my own research to try to find a way to improve quality of life...
  • Thinking about methadone maintenance? don't do it (3 responses)
    I'm on Methadone Maintenance Therapy (MMT) after failing to stay off of chronic and illicit use of heroin, dilaudid, and methamphetamines. I tried going clean using the subutex/ suboxone method twice and wasn't able to stop using the other drugs.



    With MMT I am clean of the illicit drugs, but I feel horrible all the time. I've been on it 2 years now and have been adjusting my dose up and down and find at 70mgs I have the least side effects. The side effects I have all the time are weight gain (even though I have little to no appetite), lack of motivation, very irregular menstrual cycle, and increased anxiety. Sometimes I have horrendous headaches, severe sweating, dehydration, constipation, and the worst depression I have ever had.



    If you are thinking about going on MMT, one important fact that the clinic does not tell you is how long it takes to get off of it. I'm just starting my detox now and they can only take me down 1mg a week til I'm at 35, then depending on how I'm doing I can stop and go on suboxone for withdrawals IF I'm doing ok. Do the math, that's 35 weeks until I can get to a point where I might be able to stop taking it! I really wish someone would have explained that to me when I signed up, because now I'm still a slave to drugs-just a different one at a clinic.

More reviews for: Promethazine, Suboxone

Comments from related studies:

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Complete drug side effects:

On eHealthMe, Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat opiate withdrawal. Promethazine (promethazine hydrochloride) is often used to treat nausea. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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