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Review: Suboxone and Seroquel

This review analyzes the effectiveness and drug interactions between Suboxone and Seroquel. It is created by eHealthMe based on 246 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 5, 2014: 246 people who reported to have interactions when taking Suboxone, Seroquel are studied

Trend of Suboxone, Seroquel's drug interactions, side effects and effectiveness reports (4920793)

Drug combinations in study:
- Suboxone (buprenorphine hydrochloride; naloxone hydrochloride)
- Seroquel (quetiapine fumarate)

eHealthMe real world results:

Most common interactions experienced by people in the use of Suboxone, Seroquel:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety84
Vomiting72
Decreased Appetite (decreased appetite occurs when you have a reduced desire to eat)66
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)64
Depression64
Insomnia (sleeplessness)62
Fatigue (feeling of tiredness)61
Nausea (feeling of having an urge to vomit)50
Suicidal Ideation50
Loss Of Consciousness44

Most common interactions experienced by people in long term use of Suboxone, Seroquel:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety27
Fall22
Insomnia (sleeplessness)16
Nausea (feeling of having an urge to vomit)16
Loss Of Consciousness16
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)16
Thinking Abnormal12
Back Pain12
Feeling Abnormal12
Oedema Peripheral (superficial swelling)12

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Suboxone0.00%20.00%40.00%20.00%20.00%
Seroquel0.00%0.00%25.00%50.00%25.00%

Top conditions involved for these people * :

  1. Drug dependence
  2. Depression
  3. Bipolar disorder
  4. Anxiety
  5. Insomnia

Top co-used drugs for these people * :

  1. Klonopin
  2. Cymbalta
  3. Xanax
  4. Buprenorphine hcl and naloxone hcl
  5. Zoloft

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Seroquel, Suboxone

You can also:

Complete drug side effects:

On eHealthMe, Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat opiate withdrawal. Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (6 months ago):

  • Have had renal failure in the past

    Reply

  • From this study (1 year ago):

  • MAL on Jul, 27, 2011:

    I AM TAKING SUBOXONE PLUS RESPIRADOL ,THE SUBOXONE CAUSES ME TO BE EXTREMLY PARONOID, THIS IS MY THIRD ATTEMPT AT SUBOXONE, 1ST ONE I LASTED I WEEK AS I WAS VERY PARONOID, 2ND TRY LASTED 3 WEEKS BECAME PARONOID, WENT BACK TO TAKING PANADINE FORTE, EVENTUALLY GOT BACK ON SUBOXONE,BEEN ON IT FOR NEARLY SIX MONTHS, 24MG,EXTREMLY PARONOID,WHEN I GO OFF SUBOXONE PARANOIA STOPS, I ALSO WET MY BED EVERY NIGHT WHICH IS VERY TROUBLESOME,HAS ANYONE ELSE HAD SIMILAR PROBLEMS? IT IS LIKE I AM NOT ON MY RESPIRDOL AT ALL, WHICH I AM,

    Reply

    Donna L. on Dec, 3, 2011:

    I wanted to let you know instead of suboxone they have VIVATROL NOW it's a once a month shot. the outcome looks great. I know person on it n she is doing very well.

    Reply

    scott on Sep, 5, 2012:

    dude,
    I have been on subs for 3 years, ive never taken more than 8 mg, thats after 4 years of being a junkie, no one needs 3 8mg pills, no one needs 2 8mg pills. After about a month i was down to 1, 2mg pill a day i have no cravings, it helps with my pain, i have no adverse side effects from 2mg a day. The only reason docs prescribe so much is profit, there is no money to made off of selling 30 1.75 pills. so they sell you 90 9.00 pills. Take my advice ween urself down to 4mg a day over 30 days, and i would be willing to bet your side effects go away

    Reply

    Jennifer on Oct, 11, 2012:

    Hello,
    I have been Pain pill free for a year at the beginning of this month and have been taking 1 8MG suboxone sublingual film two times daily for the entire duration of my treatment (which is an actual outpatient program with meetings, therapists, drug tests,, groups, the whole 9) not just a trip to the doctor to score another pain med). Anywho, I was taking between 20-50 pain pills a day (a mix of Dilaudid, Vicodin, Roxycontin Ultrams and percocets) for about 4 years prior to beginning treatment before I decided enough was enough and that I needed help, especially since I am now only 24 almost 25 and have been taking pain meds for my back since I had 4 herniated discs at age 16, (and then a major spinal replacement surgery several years after due to spinal nerves being severed at a rate that would soon leave me paralyzed basically, hence the upheavel in my addiction). I have noticed from the beginning that I have had joint and ankle pain and it is now to the point that if I try to bend down, my knees just buckle bc it hurts that bad. I have never had a problem with my knees aching or throbbing in pain as they are now. My doctor insists that it "is certainly not from the suboxone" but I know she's just saying that out of fear that ill stop taking it an go running back to pain pills, which will never be a part of my life again though. I really think this pain is from the suboxone, what do you think? It's gotten so bad I have actual brushing on my knee caps. I've decided to get some feedback from other suboxone users and then going to my orthopedic surgeon to have him double check that there is no actual problem with my knees( one far far worse than the other). Any feedback would be appreciated. Thanks guys

    Reply

    Crystal on Oct, 19, 2012:

    I am 28 yrs old female and i an also on suboxione,for 2 yrs now,plus cymbalta,buspar.i can say with experience of suboxione, ur dosage is a little much,for what it's worth,try to slowly decrease your mgs and see what makes you feel better,not so parinoid....good luck , : !

    Reply

    Brit on Oct, 24, 2012:

    I agree with Scott 110%. I'm down to 2 mg twice daily, and I could really stand to cut out the second dose. The goal here is to let life be manageable again, and mine is; however, after about 2 years of being on suboxone, I've started to experience intense joint pain in my fingers and toes mainly. Also psoriasis. All signs point to psoriatic arthritis which is what I've diagnosed myself with. I'm just wondering how extreme this link is between arthritis and suboxone. You can read right on the suboxone website and swollen limbs are definitely a side effect. If anyone has any further info please let me know. Thanks and I wish everyone the best!!!

    Reply

    Jennifer on Oct, 24, 2012:

    Hi Brit,
    I too have had severe joint pain as swelling from an the 4th-6th month I was on suboxone up until now where it's very very severe. I had to go to the ER bc my feet and legs were so swollen when I woke up one morning I could not wear a single pair of shoes I own. They did an EKG and many other tests, only to tell me that basically suboxone may or may not be related to this and if the case is severe, it can be a mild form of an allergic reaction to either the dosage or the medication I general. But of course my psychiatrist told me it wasn't related at all and that it was probably just a combination of sitting all day and stress (maybe she thinks I'm a complete idiot, or she just assumes I will stop suboxone if I know the truth, who knows). I have such a high dosage bc of the amount of pain pills I was taking on a daily basis, exceeding a combo of 30-50 daily however now I think since it's been a year and a month since starting treatment, it's time to taper down. As you said, my goal was to see my life as manageable again without the medication.

    Reply

    Brit on Oct, 24, 2012:

    Thats crazy & yes you're totally right about these doctors and pharmesuitical companies... They want our money and they want to keep us sick. I truly believe that. There are good doctors out there, but I keep finding more and more that natural is the way to go. The gov released a new study recently about vitamins and how we shouldn't take them bc there's no evidence that they work. Hahaha yeah I guess there wouldn't be evidence from a government study backed by drug companies. I'm proud of you for getting sober! I totally hear you! I started out taking 4 8mg tablets a day. It got me off opiates, but looking back I can't even understand how I functioned on all that suboxone. It's crazy! Now sometimes I get sick to my stomach just from taking my small dose. I too am tapering off, well trying to. I am finding a bit of challenge in it, but knowing how horrible these meds are for my body is helping my case. It's frustrating. I always encourage people to never start taking opiates bc they can't even imagine how horrible they really are. They ruin lives. Jen feel free to email me. I'd like to talk w you. My email is sincerelybrittanyboutique AT gmail dot com

    Reply

    Dj on Nov, 7, 2012:

    Actually that's only partially true Scott. That's true if u never inject these nasty devils. I did subutex 8mg a day split into 2 mg doses for a long time. And when I quit the needle and tried to dose I needed 8 mg for every 2mg shot just to hold me. Unfortunately this happened after 70% of the top of my thick hair fell out. This drug is an endocrine and nervous system nightmare. It stores in your fat and takes a good 3 weeks just to get out of your system then the dreaded paws. My advice taper as slow as u possibly can. Or go back to shorter acting opiates for a month and bite that bullet. But never try and jump from a high sub dose as it may leave permanent lifelong damage like in my case.

    Reply

    Figster on Nov, 9, 2012:

    Ok, Brit, let's get this straight; You are an opiod addict, converted to a long acting partial opiod agonist, weaning down on the medication. The study on vitamins wasn't a plot. In excess some cn be harmful. If you have success kicking opiod dependency using vitamins please let us know. You are sick, it's not doctors or companies wanting to maintain that condition. Are you doing better than before your subtext? Opiod dependency will likely need lifelong management, perhaps with suboxone; 4 mg per day is less than 4$; how much were you spending?
    People get mad and start blaming the doctors and the Meds; Some will get off, go into decline and return to using. Hope that's not you, man.

    Reply

    Figster on Nov, 9, 2012:

    Scott,
    Most physicians do not make money on dispensing medication but on the visit. The doctor who prescribed to you saved you with the Meds. You are down to 2 mg but saying "nobody" needs more than a specified amount is ludicrous. Average dose is roughly 12-16 mg in the beginning and most can wean down to 4 mg or even 2. Unless its a rare situation, your physician makes no more money having you on a higher dose. Good luck man, don't be hatin'

    Reply

  • From this study (2 years ago):

  • Just wondering if these drugs are safe.

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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