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Home > Sulfasalazine > Methotrexate > Sulfasalazine and Methotrexate

Review: Sulfasalazine and Methotrexate

Summary: drug interactions are reported among people who take Sulfasalazine and Methotrexate together.

This review analyzes the effectiveness and drug interactions between Sulfasalazine and Methotrexate. It is created by eHealthMe based on reports of 4,060 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Sulfasalazine and Methotrexate >>>

What are the drugs

Sulfasalazine (latest outcomes from 11,738 users) has active ingredients of sulfasalazine. It is often used in rheumatoid arthritis.

Trend of sulfasalazine reports

Methotrexate (latest outcomes from 131,185 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Trend of methotrexate reports

On Nov, 25, 2014: 4,059 people who take Sulfasalazine, Methotrexate are studied

Sulfasalazine, Methotrexate outcomes

Drug combinations in study:
- Sulfasalazine (sulfasalazine)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Sulfasalazine is effective0.00%
(0 of 3 people)
0.00%
(0 of 11 people)
8.33%
(1 of 12 people)
0.00%
(0 of 10 people)
25.00%
(3 of 12 people)
55.56%
(5 of 9 people)
75.00%
(3 of 4 people)
n/a
Methotrexate is effectiven/a0.00%
(0 of 14 people)
0.00%
(0 of 7 people)
35.71%
(5 of 14 people)
35.29%
(6 of 17 people)
0.00%
(0 of 3 people)
66.67%
(4 of 6 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaPyrexiaInterstitial Lung DiseasePneumoniaPyrexiaPyrexiaRenal FailurePyrexia
PneumoniaDecreased AppetitePneumoniaRenal FailureWeight DecreasedPulmonary FibrosisPleural EffusionPneumonia
Colitis IschaemicPneumoniaWeight DecreasedTonsil CancerPneumoniaAcute Interstitial PneumonitisRheumatoid ArthritisArthralgia
Rheumatoid ArthritisFatigueAstheniaPyrexiaInterstitial Lung DiseaseAcute Phase ReactionSpinal DisorderRheumatoid Arthritis
Dermatitis AllergicFallArthralgiaRheumatoid ArthritisPulmonary FibrosisPneumoniaAnaemiaDyspnoea
HypersensitivityVomitingPneumocystis Jiroveci PneumoniaPleural EffusionAnaemiaDiverticulitisAstheniaDrug Ineffective
Condition AggravatedNauseaHypoalbuminaemiaDyspnoeaDyspnoeaRenal FailureAtrial FibrillationNausea
RashDiarrhoeaDisseminated Intravascular CoagulationNasopharyngitisArthralgiaTonsil CancerCardiac Failure ChronicDiarrhoea
Metastases To LungCoughHyponatraemiaBreast CancerAstheniaUrinary Tract InfectionChillsInjection Site Pain
ArthritisDyspnoeaHepatorenal SyndromeMalaiseAcute Phase ReactionGeneral Physical Health DeteriorationHypothyroidismFatigue

Drug effectiveness by gender :

FemaleMale
Sulfasalazine is effective17.50%
(7 of 40 people)
23.81%
(5 of 21 people)
Methotrexate is effective30.00%
(12 of 40 people)
14.29%
(3 of 21 people)

Most common drug interactions by gender * :

FemaleMale
PyrexiaPneumonia
Rheumatoid ArthritisPyrexia
DiarrhoeaArthralgia
NauseaDrug Ineffective
PneumoniaPulmonary Fibrosis
ArthralgiaRheumatoid Arthritis
DyspnoeaDyspnoea
Injection Site PainFatigue
Drug IneffectivePain
CoughWeight Decreased

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Sulfasalazine is effectiven/a0.00%
(0 of 1 people)
0.00%
(0 of 4 people)
0.00%
(0 of 9 people)
9.09%
(1 of 11 people)
23.81%
(5 of 21 people)
4.35%
(1 of 23 people)
17.24%
(5 of 29 people)
Methotrexate is effectiven/a100.00%
(1 of 1 people)
25.00%
(1 of 4 people)
22.22%
(2 of 9 people)
18.18%
(2 of 11 people)
20.00%
(4 of 20 people)
4.17%
(1 of 24 people)
13.79%
(4 of 29 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aPyrexiaPyrexiaPyrexiaArthralgiaDiarrhoeaPyrexiaPneumonia
Juvenile Rheumatoid ArthritisRespiratory FailureHeadachePyrexiaPyrexiaDrug IneffectivePyrexia
Condition AggravatedInfectionArthralgiaVomitingAbdominal PainRheumatoid ArthritisDyspnoea
Pain NosDemyelinationDrug HypersensitivityHypoaesthesiaContusionArthralgiaInterstitial Lung Disease
Joint StiffnessCondition AggravatedPainDiarrhoeaPneumoniaCoughRheumatoid Arthritis
Vanillyl Mandelic Acid Urine IncreasedBlood Pressure DecreasedRheumatoid ArthritisGait DisturbanceThrombocytopeniaPainArthralgia
DysphagiaDyspnoeaImpaired HealingNauseaHaematemesisPneumoniaPulmonary Fibrosis
AstheniaInfusion Related ReactionDermatitisFallFull Blood Count AbnormalFatigueDrug Ineffective
Pulmonary Alveolar HaemorrhageChest PainPruritusDizzinessRheumatoid ArthritisWeight DecreasedNausea
Acute Graft Versus Host Disease In IntestineRenal Failure AcuteEczemaBack PainNauseaNauseaSepsis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Sulfasalazine and Methotrexate?

You are not alone! Join a related mobile support group:
- support group for people who take Sulfasalazine and Methotrexate
- support group for people who take Methotrexate
- support group for people who take Sulfasalazine

Recent conversations of related support groups:

Latest outcomes in real world:

Can you answer these questions (Ask a question):

  • What side effects do you experience from sulpfasalazine?
    (Asked by a 58 year old woman who has Rheumatoid Arthritis, and takes Sulfasalazine)
    I began taking sulfasalazine 5 days ago for Rheumatoid arthritis. Since then I've had stomach cramps and bloating. Has anyone else experienced these side effects? If so, did the symptoms go away after using taking the meds for a while? And did the meds help the RA symptoms?

  • Hlab27 antigen and unexplained scratches caused by accutane
    (Asked by a 49 year old woman who has Scratches, Swelling, Burning, Nerve, Muscle Pain, Conjunctivitis, and takes Methotrexate)
    Guinea pig user of Accutane 1982. Experimental drug (told at that time) when a woman hits menopause we are not sure what will happen. I have hit early menopause 42 to be exact. Conjunctivitis, unexplained swelling in fingers, toes, kness, pseudogout (not normal according to my rheumatologist) une ...

  • Has anybody had multi lobar pneumonia from reaction to methotrexate?
    (Asked by a 57 year old woman who has Migraine Without Aura, Anxiety And Stress, Major Depression With Psychotic Features, Bilateral Multilobar Pneumonia, Ankylosing Spondylitis, and takes Zyprexa, Methotrexate)
    Bilateral multilobar pneumonia - rheumatologist considers it was caused by a reaction to methotrexate I was taking for ankylosing spondylitis and I was lucky to survive. Anyone have this and later shown to have scarring of the lungs?

  • I am a 56 year old female with rheumatoid arthritis. i also have found out i have osteoporosis. i keep getting right breast sensitivity also tingling and tenderness in right scapula area...
    (Asked by a 56 year old woman who has Hign Blood Pressure, Osteoporosis Postmenopausal, Rheumatoid Arthritis, and takes Methotrexate)
    I am a 56 year old female with tingling in my right shoulder blade and some tenderness. I have occasional breast discomfort in the same side and sometimes my rt. nipple feels sensitive. If I touch the area, the symptom on the nipple vanishes. at times the tingling travels into my neck and symptoms s ...

  • Can i take marijuana while taking gilenya
    (Asked by a 36 year old woman who has MS, and takes Gilenya)
    Hello i would like to know if is safe to have marijuane with gilenya and methotraxate

More questions for: Methotrexate, Sulfasalazine

You may be interested at these reviews (Write a review):

  • Humira: my experience
    (Posted by a 66 year old man who has Ankylosing Spondylitis, Reiter's Syndrome, Psoriatic Arthritis, and takes Methotrexate Preservative Free, Enbrel, Humira)
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long. I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, ...

  • Sulfasalazine and the never ending menstrual cycle
    (Posted by a 43 year old woman who has Arthritis - Rheumatoid, and takes Sulfasalazine)
    I started this drug and never had menstrual problems begore. Within 3 months, I started my period and it never stopped even with stopping the drug for 3 mon ths. I ended up going my gyne and he prescribed megace. I had been bleeding for a total of 6 months. Made an appt with my rhuemy and explai ...

  • Psoratic arthritis and trigeminal neuralgia
    (Posted by a 33 year old man who has Nasal Septum Deviation, Psoriasis, Psoriatic Arthritis, Trigeminal Neuralgia, Asthma Exercise Induced, and takes Methotrexate)
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic a ...

  • Spiriva caused me to swell up like a hippo.
    (Posted by a 46 year old woman who has Rheumatoid Arthritis, Irritable Bowel Syndrome, and takes Advair Diskus 250/50, Methotrexate, Plaquenil, Metformin, Klonopin, Zanaflex, Prednisone, Singulair, Imitrex, Nexium)
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen ...

  • Personalized review of arava
    (Posted by a 65 year old woman who has Rheumatoid Arthritis, and takes Methotrexate)
    Have had RA for 10 years and was on Methotrexate those 10 years. Had nose bleeds which got progressively worse over the years and began to effect my quality of living. Doctor said it could NOT be the drug, but according to eHealth Me, it could. At urging of an ENT, I stopped taking Methotrexate ...

More reviews for: Methotrexate, Sulfasalazine

Complete drug side effects:

On eHealthMe, Sulfasalazine (sulfasalazine) is often used to treat rheumatoid arthritis. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Methotrexate, Sulfasalazine

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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