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Review: taking Sulfasalazine and Methotrexate together

Summary: drug interactions are reported among people who take Sulfasalazine and Methotrexate together.

This review analyzes the effectiveness and drug interactions between Sulfasalazine and Methotrexate. It is created by eHealthMe based on reports of 4,061 people who take the same drugs from FDA and social media, and is updated regularly.

 

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On Feb, 27, 2015: 4,060 people who take Sulfasalazine, Methotrexate are studied

Sulfasalazine, Methotrexate outcomes

Drug combinations in study:
- Sulfasalazine (sulfasalazine)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Sulfasalazine is effective0.00%
(0 of 3 people)
0.00%
(0 of 11 people)
8.33%
(1 of 12 people)
0.00%
(0 of 10 people)
30.77%
(4 of 13 people)
55.56%
(5 of 9 people)
75.00%
(3 of 4 people)
n/a
Methotrexate is effectiven/a0.00%
(0 of 14 people)
0.00%
(0 of 7 people)
35.71%
(5 of 14 people)
38.89%
(7 of 18 people)
0.00%
(0 of 3 people)
66.67%
(4 of 6 people)
n/a

Drug effectiveness by gender :

FemaleMale
Sulfasalazine is effective19.51%
(8 of 41 people)
23.81%
(5 of 21 people)
Methotrexate is effective31.71%
(13 of 41 people)
14.29%
(3 of 21 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Sulfasalazine is effectiven/a0.00%
(0 of 1 people)
0.00%
(0 of 4 people)
0.00%
(0 of 9 people)
16.67%
(2 of 12 people)
23.81%
(5 of 21 people)
4.35%
(1 of 23 people)
17.24%
(5 of 29 people)
Methotrexate is effectiven/a100.00%
(1 of 1 people)
25.00%
(1 of 4 people)
22.22%
(2 of 9 people)
25.00%
(3 of 12 people)
20.00%
(4 of 20 people)
4.17%
(1 of 24 people)
13.79%
(4 of 29 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PyrexiaPyrexiaInterstitial Lung DiseasePneumoniaPyrexiaPyrexiaRenal FailurePyrexia
PneumoniaDecreased AppetitePneumoniaRenal FailureWeight DecreasedPulmonary FibrosisPleural EffusionPneumonia
Colitis IschaemicPneumoniaWeight DecreasedTonsil CancerPneumoniaAcute Interstitial PneumonitisRheumatoid ArthritisArthralgia
Rheumatoid ArthritisFatigueAstheniaPyrexiaInterstitial Lung DiseaseAcute Phase ReactionSpinal DisorderRheumatoid Arthritis
Dermatitis AllergicFallArthralgiaRheumatoid ArthritisAnaemiaPneumoniaAnaemiaDyspnoea
HypersensitivityVomitingPneumocystis Jiroveci PneumoniaPleural EffusionPulmonary FibrosisDiverticulitisAstheniaDrug Ineffective
Condition AggravatedNauseaHypoalbuminaemiaDyspnoeaDyspnoeaRenal FailureAtrial FibrillationNausea
RashDiarrhoeaDisseminated Intravascular CoagulationNasopharyngitisArthralgiaTonsil CancerCardiac Failure ChronicDiarrhoea
Metastases To LungCoughHyponatraemiaBreast CancerAstheniaUrinary Tract InfectionChillsInjection Site Pain
ArthritisDyspnoeaHepatorenal SyndromeMalaiseAcute Interstitial PneumonitisGeneral Physical Health DeteriorationHypothyroidismFatigue

Most common drug interactions by gender * :

FemaleMale
PyrexiaPneumonia
Rheumatoid ArthritisPyrexia
DiarrhoeaArthralgia
NauseaDrug Ineffective
ArthralgiaPulmonary Fibrosis
PneumoniaRheumatoid Arthritis
DyspnoeaDyspnoea
Injection Site PainFatigue
Drug IneffectivePain
CoughWeight Decreased

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aPyrexiaPyrexiaPyrexiaArthralgiaDiarrhoeaPyrexiaPneumonia
Juvenile Rheumatoid ArthritisRespiratory FailureHeadachePyrexiaPyrexiaDrug IneffectivePyrexia
Condition AggravatedInfectionArthralgiaVomitingAbdominal PainRheumatoid ArthritisDyspnoea
Pain NosDemyelinationDrug HypersensitivityHypoaesthesiaContusionArthralgiaInterstitial Lung Disease
Joint StiffnessCondition AggravatedPainDiarrhoeaPneumoniaCoughRheumatoid Arthritis
Vanillyl Mandelic Acid Urine IncreasedBlood Pressure DecreasedRheumatoid ArthritisFallThrombocytopeniaPainArthralgia
DysphagiaDyspnoeaImpaired HealingNauseaHaematemesisPneumoniaPulmonary Fibrosis
AstheniaInfusion Related ReactionDermatitisGait DisturbanceFull Blood Count AbnormalFatigueDrug Ineffective
Pulmonary Alveolar HaemorrhageChest PainPruritusDizzinessRheumatoid ArthritisWeight DecreasedNausea
Acute Graft Versus Host Disease In IntestineRenal Failure AcuteEczemaMuscle AtrophyNauseaNauseaSepsis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Sulfasalazine and Methotrexate?

 

 

 

You are not alone! Join a related mobile support group on :
- support group for people who take Methotrexate
- support group for people who take Sulfasalazine

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Sulfasalazine (sulfasalazine) is often used to treat rheumatoid arthritis. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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