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Review: taking Sumatriptan Succinate and Tramadol together

Summary: drug interactions are reported among people who take Sumatriptan Succinate and Tramadol together.

This review analyzes the effectiveness and drug interactions between Sumatriptan Succinate and Tramadol. It is created by eHealthMe based on reports of 440 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 27, 2015: 440 people who take Sumatriptan Succinate, Tramadol are studied

Sumatriptan Succinate, Tramadol outcomes

Drug combinations in study:
- Sumatriptan Succinate (sumatriptan succinate)
- Tramadol (tramadol hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Sumatriptan Succinate is effective50.00%
(1 of 2 people)
(2 of 4 people)
(0 of 2 people)
(3 of 5 people)
(2 of 6 people)
(3 of 3 people)
(4 of 5 people)
Tramadol is effective50.00%
(2 of 4 people)
(2 of 2 people)
(1 of 7 people)
(1 of 1 people)
(3 of 7 people)
(1 of 5 people)
(0 of 2 people)

Drug effectiveness by gender :

Sumatriptan Succinate is effective54.55%
(12 of 22 people)
(3 of 5 people)
Tramadol is effective30.43%
(7 of 23 people)
(3 of 5 people)

Drug effectiveness by age :

Sumatriptan Succinate is effectiven/an/an/a14.29%
(1 of 7 people)
(5 of 9 people)
(3 of 42 people)
(3 of 9 people)
(3 of 7 people)
Tramadol is effectiven/an/an/a14.29%
(1 of 7 people)
(3 of 10 people)
(3 of 43 people)
(2 of 9 people)
(1 of 6 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
PainCyanosisHeart Rate IrregularGallbladder InjuryDeep Vein ThrombosisFibromyalgiaDepressionPain
General Physical Health DeteriorationPeripheral IschaemiaOedema PeripheralDizzinessPainPain - JointsLigament InjuryNausea
Visual ImpairmentAnxietyDyspnoeaVomitingPain In ExtremityLupusGallbladder InjuryDeep Vein Thrombosis
Superior Sagittal Sinus ThrombosisPainDeep Vein ThrombosisBiliary DyskinesiaOedema PeripheralDiabetes MellitusCholelithiasisVomiting
Neck PainEmotional DistressLightheadednessHaematemesisInjuryPainful Response To Normal StimuliCholecystitis ChronicAnxiety
NauseaArterial ThrombosisAtelectasisNauseaChest PainConfusionGallbladder DisorderMigraine
Emotional DistressDrug HypersensitivityPain In ExtremityAbdominal PainDyspnoeaChest PainIntentional OverdoseHeadache
MigraineSerotonin SyndromePulmonary EmbolismDiarrhoeaDepressionAmmonia IncreasedPancreatitisInjury
Grand Mal ConvulsionAdrenal InsufficiencySyncopeHaematocheziaNauseaSjogren's SyndromeLiver Function Test AbnormalHypoaesthesia
InjuryHeart Rate IncreasedMigraine - CommonAmmonia IncreasedFatigueImmunosuppressant Drug Level DecreasedAggressionPain In Extremity

Most common drug interactions by gender * :

PainSerotonin Syndrome
NauseaPain In Extremity
Deep Vein ThrombosisNeck Pain
VomitingRotator Cuff Syndrome
DepressionCompression Fracture
HypoaesthesiaMusculoskeletal Pain

Most common drug interactions by age * :

n/an/aAccidental OverdoseTorsade De PointesPainPainNauseaMigraine
ManiaNauseaAnxietyAnxietyBlood Glucose IncreasedFall
Sphincter Of Oddi DysfunctionPainHeadacheDepressionVomitingRib Fracture
PainAdrenal InsufficiencyEmotional DistressHeadacheDiarrhoeaPain
Gallbladder DisorderCardiac ArrestPain In ExtremitySerotonin SyndromePain In ExtremityAnkle Fracture
Cholecystitis ChronicVentricular FibrillationDyspnoeaFatigueDeep Vein ThrombosisVitamin D Deficiency
PancreatitisDeep Vein ThrombosisDepressionNauseaArthralgiaEmotional Distress
HeadacheVision BlurredNauseaDeep Vein ThrombosisInjuryBone Density Decreased
Throat TightnessBrain DeathDeep Vein ThrombosisHypoaesthesiaNeck PainOsteopenia
Deep Vein ThrombosisVomitingOedema PeripheralEmotional DistressAnaemiaBone Loss

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Sumatriptan Succinate
- support group for people who take Tramadol

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Sumatriptan Succinate (sumatriptan succinate) is often used to treat migraine. Tramadol (tramadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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