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Review: Synthroid and L-Lysine

Summary: drug interactions are reported among people who take Synthroid and L-Lysine together.

This review analyzes the effectiveness and drug interactions between Synthroid and L-Lysine. It is created by eHealthMe based on reports of 78 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Synthroid and L-Lysine >>>

What are the drugs

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Synthroid 93,746 users)

L-lysine has active ingredients of lysine. It is often used in herpes labialis (oral herpes simplex). (latest outcomes from L-lysine 213 users)

On Dec, 14, 2014: 78 people who take Synthroid, L-Lysine are studied

Synthroid, L-Lysine outcomes

Drug combinations in study:
- Synthroid (levothyroxine sodium)
- L-Lysine (lysine)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Synthroid is effectiven/an/a0.00%
(0 of 1 people)
(1 of 1 people)
(1 of 1 people)
(2 of 2 people)
(1 of 2 people)
L-Lysine is effectiven/a0.00%
(0 of 2 people)
(1 of 1 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
n/aLip Swellingn/aDark Circles Under Eyesn/aDark Circles Under EyesLip SwellingDeep Vein Thrombosis
Pain In Extremity
Platelet Count Decreased
Diabetes Mellitus
Ear Infection
Platelet Count Increased

Drug effectiveness by gender :

Synthroid is effective66.67%
(4 of 6 people)
(1 of 1 people)
L-Lysine is effective50.00%
(2 of 4 people)

Most common drug interactions by gender * :

Pain In ExtremityCardiac Arrest
Deep Vein ThrombosisAtrioventricular Block
DiarrhoeaDiabetes Mellitus
Platelet Count DecreasedUpper Limb Fracture
MalaiseIll-defined Disorder
Upper Respiratory Tract InfectionGastrointestinal Disorder
DyspnoeaDrug Ineffective
Platelet Count IncreasedSwelling

Drug effectiveness by age :

Synthroid is effectiven/an/an/an/an/a100.00%
(2 of 2 people)
(3 of 3 people)
(0 of 10 people)
L-Lysine is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
(0 of 1 people)
(1 of 10 people)

Most common drug interactions by age * :

n/an/an/aInjection Site WarmthPulmonary EmbolismGallbladder DisorderCandidiasisPlatelet Count Decreased
Injection Site SwellingDeep Vein ThrombosisBiliary DyskinesiaEar InfectionAtrioventricular Block
Injection Site ErythemaFacial ParesisDark Circles Under EyesUpper Respiratory Tract InfectionCardiac Arrest
Injection Site NoduleBasal Ganglia InfarctionLip SwellingFemur FractureAccident
Muscular WeaknessTibia FractureDeep Vein Thrombosis
Cerebral Artery EmbolismFoot FracturePlatelet Count Increased
DyspnoeaFibula FracturePain In Extremity
Pain In ExtremityHip FractureDiabetes Mellitus
PneumoniaBack PainNausea
Restless Legs SyndromeSinusitisUpper Limb Fracture

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Synthroid and L-Lysine?

You are not alone! Join a related mobile support group:
- support group for people who take Synthroid and L-Lysine
- support group for people who take L-Lysine
- support group for people who take Synthroid

Can you answer these questions (Ask a question):

More questions for: L-Lysine, Synthroid

You may be interested at these reviews (Write a review):

  • Cardio version caused fingernail abnormalities
    Right hip fracture. When prepping for surgery AFIB was found. Surgery was cancelled and they attempted to get AFIB under control. Finally, cardioversion was performed. When my nails started to grow out they all had two horizontal lines that cause the nail to break when it grows out to that point.
  • Synthroid and breast enlargement
    I have went from a B-C cup size to a D cup in the past 8-9 months.
  • Weight loss taking lipitor
    Did not want to take Lipitor heard a lot about it dr made me I weighed 164 was on Lipitor for 2years lost down to 132 and still losing how do I regain some weight back I look horrible
  • Double vision on levothyroxine
    Diagnosed with under active thyroid in January 2011. Noticed onset of double vision in January 2014. Blurred vision and double vision worsened to such an extent that my glasses prescription has changed three times in less than 7 months. All the symptons I experience are a direct result of taking Levothyrixine and have increased as my dose has been increased.
  • I switched to armour ,it's not synthetic.
    I went off after 7 years on it when I discovered a link to a higher rate of lung cancer. I switched to Armour and it handled the hypothyroidism way better.

More reviews for: L-Lysine, Synthroid

Comments from related studies:

  • From this study (2 years ago):

  • Acid Reflux has worsen with weight gain. Acid Reflux conditions have had off and on the last 10 year getting worse the last 3 years. Synthroid treatment for 20 years. Acid reflux worsening as I age; 70 years old.


Complete drug side effects:

On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. L-lysine (lysine) is often used to treat herpes labialis (oral herpes simplex). Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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