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Review: Synthroid and L-Lysine

This review analyzes the effectiveness and drug interactions between Synthroid and L-Lysine. It is created by eHealthMe based on reports of 78 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Synthroid and L-Lysine >>>

What are the drugs

Synthroid (what 93,655 Synthroid users reported?) has active ingredients of levothyroxine sodium. It is used in hypothyroidism.

L-lysine (what 212 L-lysine users reported?) has active ingredients of lysine. It is used in herpes labialis (oral herpes simplex).

On Sep, 10, 2014: 78 people who take Synthroid, L-Lysine are studied

Synthroid, L-Lysine outcomes

Drug combinations in study:
- Synthroid (levothyroxine sodium)
- L-Lysine (lysine)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Synthroid is effectiven/an/a0.00%
(0 of 1 people)
(1 of 1 people)
(1 of 1 people)
(2 of 2 people)
(1 of 2 people)
L-Lysine is effectiven/a0.00%
(0 of 2 people)
(1 of 1 people)
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
n/aLip Swellingn/aDark Circles Under Eyesn/aDark Circles Under EyesLip SwellingDeep Vein Thrombosis
Pain In Extremity
Platelet Count Decreased
Diabetes Mellitus
Ear Infection
Platelet Count Increased

Drug effectiveness by gender :

Synthroid is effective66.67%
(4 of 6 people)
(1 of 1 people)
L-Lysine is effective50.00%
(2 of 4 people)

Most common drug interactions by gender * :

Pain In ExtremityCardiac Arrest
Deep Vein ThrombosisAtrioventricular Block
DiarrhoeaDiabetes Mellitus
Platelet Count DecreasedUpper Limb Fracture
MalaiseIll-defined Disorder
Upper Respiratory Tract InfectionGastrointestinal Disorder
DyspnoeaDrug Ineffective
Platelet Count IncreasedSwelling

Drug effectiveness by age :

Synthroid is effectiven/an/an/an/an/a100.00%
(2 of 2 people)
(3 of 3 people)
(0 of 10 people)
L-Lysine is effectiven/an/an/an/an/a100.00%
(1 of 1 people)
(0 of 1 people)
(1 of 10 people)

Most common drug interactions by age * :

n/an/an/aInjection Site WarmthPulmonary EmbolismGallbladder DisorderCandidiasisPlatelet Count Decreased
Injection Site SwellingDeep Vein ThrombosisBiliary DyskinesiaEar InfectionAtrioventricular Block
Injection Site ErythemaFacial ParesisDark Circles Under EyesUpper Respiratory Tract InfectionCardiac Arrest
Injection Site NoduleBasal Ganglia InfarctionLip SwellingFemur FractureAccident
Muscular WeaknessTibia FractureDeep Vein Thrombosis
Cerebral Artery EmbolismFoot FracturePlatelet Count Increased
DyspnoeaFibula FracturePain In Extremity
Pain In ExtremityHip FractureDiabetes Mellitus
PneumoniaBack PainNausea
Restless Legs SyndromeSinusitisUpper Limb Fracture

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Synthroid and L-Lysine
- group for people who take L-Lysine
- group for people who take Synthroid

Comments from related studies:

  • From this study (2 years ago):

  • Acid Reflux has worsen with weight gain. Acid Reflux conditions have had off and on the last 10 year getting worse the last 3 years. Synthroid treatment for 20 years. Acid reflux worsening as I age; 70 years old.


Can you answer these questions (what is this?):

  • Omeprazole or pantoprazole?
    I take an oral contraceptive, Diane-35 ED, which is not in the list of drugs to choose from on this site. Recently, the medication I was taking for my stomach ulcer (Omeprazole) became unavailable in my country of residence and was replaced by Patoprazole. I started taking it yesterday morning a ...

  • Does it produce vitamin k
    he had stroke 5 years ago, he is taking sintrom, irregular heart beat

  • Has anyone been prescribed methotrexate for granuloma annulare?
    I have had GA for 2 years now, however it has gotten progressively worse the past 6 months. It has now spread over 80% of my body. I am seeing an Endocrinologist next week as I believe my thyroid may play a big role in this. My Regular Dr. suggested I speak to Endocrinologist about a drug called Met ...

More questions for: L-Lysine, Synthroid

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  • Shortness of breath after taking levothyroxine for 8-10 yrs.
    I have been experiencing shortness of breath lately when taking the levothyroxine. If I stop taking it for a couple of days my shortness of breath is pretty much gone.

  • I wish i had never taken ambien
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More reviews for: L-Lysine, Synthroid

Complete drug side effects:

On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. L-lysine (lysine) is often used to treat herpes labialis (oral herpes simplex). Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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