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Related topic: Metformin, Synthroid

Review: Synthroid and Metformin

This review analyzes the effectiveness and drug interactions between Synthroid and Metformin. It is created by eHealthMe based on 11,549 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 29, 2014: 11,549 people who reported to have interactions when taking Synthroid, Metformin are studied

Trend of Synthroid, Metformin's drug interactions, side effects and effectiveness reports (5890751)

Drug combinations in study:
- Synthroid (levothyroxine sodium)
- Metformin (metformin hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Synthroid, Metformin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Nausea (feeling of having an urge to vomit)2,779
Diarrhoea2,614
Dyspnoea (difficult or laboured respiration)2,536
Vomiting2,368
Fatigue (feeling of tiredness)2,205
Pain2,089
Blood Glucose Increased1,934
Weight Decreased1,586
Headache (pain in head)1,535
Dizziness1,505

Most common interactions experienced by people in long term use of Synthroid, Metformin:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety151
Renal Failure Acute (rapid kidney dysfunction)98
Pain89
Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)78
Nausea (feeling of having an urge to vomit)76
Cholecystitis Chronic (long lasting infection of gallbladder)72
Fatigue (feeling of tiredness)70
Chest Pain58
Abdominal Pain Upper54
Pulmonary Embolism (blockage of the main artery of the lung)50

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Synthroid4.08%8.16%20.41%45.92%21.43%
Metformin2.68%20.54%33.93%31.25%11.61%

Top conditions involved for these people * :

  1. Diabetes mellitus
  2. Hypertension
  3. Type 2 diabetes mellitus
  4. Hypothyroidism
  5. Depression

Top co-used drugs for these people * :

  1. Glucophage
  2. Aspirin
  3. Lipitor
  4. Byetta
  5. Lisinopril

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Complete drug side effects:

On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (2 weeks ago):

  • Over past 6+ years, hair has thinned by half.

    Reply

    help on Apr, 9, 2014:

    hair loss maybe due to thyroid issues?

    Reply

  • From this study (4 weeks ago):

  • I have developed severe lower right quadrant pain, nausea, blurred vision, lower back pain, dizziness, weakness, chronic fatigue, increased anxiety, night sweats, and numbing in hands and arms. My Metformin was increased from 500 mg. per day to 1500 mg. per day 3 weeks ago.

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

More questions for: Metformin, Synthroid

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More reviews for: Metformin, Synthroid

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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