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Review: Synthroid and Metformin





Summary: drug interactions are reported among people who take Synthroid and Metformin together.

This review analyzes the effectiveness and drug interactions between Synthroid and Metformin. It is created by eHealthMe based on reports of 11,985 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Synthroid and Metformin >>>

What are the drugs

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Synthroid 93,746 users)

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (view latest outcomes from 100,893 users)

On Nov, 27, 2014: 11,985 people who take Synthroid, Metformin are studied

Synthroid, Metformin outcomes

Drug combinations in study:
- Synthroid (levothyroxine sodium)
- Metformin (metformin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Synthroid is effective18.18%
(2 of 11 people)
26.19%
(11 of 42 people)
43.33%
(13 of 30 people)
36.73%
(18 of 49 people)
60.64%
(57 of 94 people)
71.13%
(69 of 97 people)
69.41%
(118 of 170 people)
100.00%
(2 of 2 people)
Metformin is effective22.73%
(5 of 22 people)
22.97%
(17 of 74 people)
39.53%
(17 of 43 people)
29.87%
(23 of 77 people)
43.27%
(45 of 104 people)
56.18%
(50 of 89 people)
36.92%
(24 of 65 people)
25.00%
(1 of 4 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaFatigueHypoplastic Left Heart SyndromePainCholecystitis ChronicAnxietyFatigueNausea
Intentional OverdoseNauseaGestational DiabetesNauseaAnxietyFatigueMetabolic AcidosisBlood Glucose Increased
DiarrhoeaDyspnoeaMaternal Exposure During PregnancyChest PainPainDizzinessHyperkalaemiaFatigue
Blood Glucose IncreasedDizzinessInfectious PeritonitisAnxietyNauseaLactic AcidosisRenal Failure AcuteWeight Decreased
Cardiac ArrestDiarrhoeaOvarian CystDyspnoeaAbdominal Pain UpperRenal Failure AcuteDizzinessDiarrhoea
HypotensionVomitingFatigueSomnolenceCholelithiasisPulmonary EmbolismHigh Blood SugarPain
PainAbdominal PainWeight IncreasedCholecystitis ChronicWeight DecreasedSudden DeathNauseaDyspnoea
Suicide AttemptEmotional DistressAnxietyBlood Glucose IncreasedFatigueDeep Vein ThrombosisElectrocardiogram Pr ProlongationVomiting
Pancreatitis AcutePainDepressionFatigueDyspnoeaDepressionPainHeadache
Lip SwellingInsomniaPainFeeling ColdHypocalcaemiaThyroid Function Test AbnormalAnxietyDizziness

Drug effectiveness by gender :

FemaleMale
Synthroid is effective57.32%
(235 of 410 people)
63.86%
(53 of 83 people)
Metformin is effective37.22%
(147 of 395 people)
42.68%
(35 of 82 people)

Most common drug interactions by gender * :

FemaleMale
NauseaBlood Glucose Increased
Blood Glucose IncreasedMyocardial Infarction
FatigueNausea
PainRenal Failure Acute
Weight DecreasedWeight Decreased
DiarrhoeaAsthenia
VomitingDiarrhoea
DyspnoeaCardiac Failure Congestive
HeadacheFatigue
DizzinessDyspnoea

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Synthroid is effectiven/an/a0.00%
(0 of 10 people)
25.45%
(14 of 55 people)
35.09%
(40 of 114 people)
28.99%
(49 of 169 people)
35.68%
(86 of 241 people)
38.98%
(99 of 254 people)
Metformin is effectiven/an/a0.00%
(0 of 6 people)
9.62%
(5 of 52 people)
28.30%
(30 of 106 people)
23.08%
(39 of 169 people)
22.22%
(54 of 243 people)
21.26%
(54 of 254 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Transposition Of The Great Vesselsn/aNauseaCholecystitis ChronicPainNauseaNauseaNausea
Type 2 Diabetes MellitusVomitingAnxietyNauseaDiabetes MellitusBlood Glucose IncreasedFatigue
Blood Cholesterol IncreasedCholelithiasisCholelithiasisAnxietyType 2 Diabetes MellitusWeight DecreasedBlood Glucose Increased
Ventricular Septal DefectCholecystitis ChronicPainType 2 Diabetes MellitusWeight DecreasedDiarrhoeaDiarrhoea
Acquired Tracheo-oesophageal FistulaHeadacheAbdominal Pain UpperChest PainDiarrhoeaHeadachePain
Cardiac MurmurAbdominal Pain UpperAbdominal PainHeadacheBlood Glucose IncreasedDyspnoeaAsthenia
Oesophageal AtresiaGallbladder CholesterolosisNauseaDiabetes MellitusPainAstheniaVomiting
Congenital Musculoskeletal AnomalyArthralgiaInjuryPulmonary EmbolismVomitingDizzinessWeight Decreased
Premature BabyTachycardiaDeep Vein ThrombosisDeep Vein ThrombosisDyspnoeaVomitingDyspnoea
Maternal Drugs Affecting FoetusMydriasisGallbladder DisorderWeight IncreasedHeadacheMyocardial InfarctionDizziness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Synthroid and Metformin?

You are not alone! Join a related mobile support group:
- support group for people who take Synthroid and Metformin
- support group for people who take Metformin
- support group for people who take Synthroid

Can you answer these questions (Ask a question):

More questions for: Metformin, Synthroid

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More reviews for: Metformin, Synthroid

Comments from related studies:

  • From this study (3 days ago):

  • I've lost 65 lbs and all of my appetite during the last 12 months. I quit taking the Metformin 6 months ago and that hasn't changed anything. I've had a CT Scan and a Gastric Emptying Study done to confirm the diagnosis. I'm having a colonoscopy and an esphogealendoscopy in January to find any further cause of the damage.

    Reply

  • From this study (2 months ago):

  • very tired most of day , daily functions being limited , type 2 diabetic ,hashimoto's , degenerative disc problem in back..

    Reply

  • From this study (2 months ago):

  • I need to find a medicine in replace of my metforminso it doesn't affect my thyroid.

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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