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Review: Synthroid and Metformin

This review analyzes the effectiveness and drug interactions between Synthroid and Metformin. It is created by eHealthMe based on reports of 11,980 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Synthroid and Metformin >>>

What are the drugs

Synthroid (latest outcomes from 93,669 users) has active ingredients of levothyroxine sodium. It is often used in hypothyroidism.

Metformin (latest outcomes from 100,800 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.

On Sep, 27, 2014: 11,980 people who take Synthroid, Metformin are studied

Synthroid, Metformin outcomes

Drug combinations in study:
- Synthroid (levothyroxine sodium)
- Metformin (metformin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Synthroid is effective18.18%
(2 of 11 people)
26.83%
(11 of 41 people)
43.33%
(13 of 30 people)
35.42%
(17 of 48 people)
61.29%
(57 of 93 people)
70.83%
(68 of 96 people)
69.41%
(118 of 170 people)
100.00%
(2 of 2 people)
Metformin is effective22.73%
(5 of 22 people)
23.29%
(17 of 73 people)
39.53%
(17 of 43 people)
29.87%
(23 of 77 people)
43.69%
(45 of 103 people)
56.32%
(49 of 87 people)
36.92%
(24 of 65 people)
25.00%
(1 of 4 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaFatigueHypoplastic Left Heart SyndromePainCholecystitis ChronicAnxietyFatigueNausea
Intentional OverdoseNauseaGestational DiabetesNauseaAnxietyFatigueMetabolic AcidosisBlood Glucose Increased
DiarrhoeaDyspnoeaMaternal Exposure During PregnancyChest PainPainDizzinessHyperkalaemiaFatigue
Blood Glucose IncreasedDizzinessInfectious PeritonitisAnxietyNauseaLactic AcidosisRenal Failure AcuteWeight Decreased
Cardiac ArrestDiarrhoeaOvarian CystDyspnoeaAbdominal Pain UpperRenal Failure AcuteDizzinessDiarrhoea
HypotensionVomitingFatigueSomnolenceCholelithiasisPulmonary EmbolismHigh Blood SugarPain
Suicide AttemptAbdominal PainWeight IncreasedCholecystitis ChronicWeight DecreasedSudden DeathNauseaDyspnoea
Pancreatitis AcutePainAnxietyBlood Glucose IncreasedFatigueDeep Vein ThrombosisElectrocardiogram Pr ProlongationVomiting
Lip SwellingEmotional DistressDepressionFatigueDyspnoeaDepressionPainHeadache
Pulmonary EmbolismRenal FailurePainFeeling ColdHypocalcaemiaThyroid Function Test AbnormalAnxietyDizziness

Drug effectiveness by gender :

FemaleMale
Synthroid is effective57.25%
(233 of 407 people)
64.63%
(53 of 82 people)
Metformin is effective37.24%
(146 of 392 people)
43.21%
(35 of 81 people)

Most common drug interactions by gender * :

FemaleMale
NauseaBlood Glucose Increased
Blood Glucose IncreasedMyocardial Infarction
FatigueNausea
PainRenal Failure Acute
Weight DecreasedWeight Decreased
DiarrhoeaAsthenia
VomitingDiarrhoea
DyspnoeaCardiac Failure Congestive
HeadacheFatigue
DizzinessDyspnoea

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Synthroid is effectiven/an/a0.00%
(0 of 10 people)
25.45%
(14 of 55 people)
35.09%
(40 of 114 people)
28.48%
(47 of 165 people)
35.98%
(86 of 239 people)
38.98%
(99 of 254 people)
Metformin is effectiven/an/a0.00%
(0 of 6 people)
9.62%
(5 of 52 people)
28.30%
(30 of 106 people)
23.03%
(38 of 165 people)
22.41%
(54 of 241 people)
21.26%
(54 of 254 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Transposition Of The Great Vesselsn/aNauseaCholecystitis ChronicPainNauseaNauseaNausea
Type 2 Diabetes MellitusVomitingAnxietyNauseaDiabetes MellitusBlood Glucose IncreasedFatigue
Blood Cholesterol IncreasedCholelithiasisCholelithiasisAnxietyType 2 Diabetes MellitusWeight DecreasedBlood Glucose Increased
Ventricular Septal DefectCholecystitis ChronicPainType 2 Diabetes MellitusWeight DecreasedDiarrhoeaDiarrhoea
Acquired Tracheo-oesophageal FistulaHeadacheAbdominal Pain UpperChest PainBlood Glucose IncreasedHeadachePain
Cardiac MurmurAbdominal Pain UpperAbdominal PainHeadacheDiarrhoeaDyspnoeaAsthenia
Oesophageal AtresiaGallbladder CholesterolosisNauseaDiabetes MellitusPainAstheniaVomiting
Congenital Musculoskeletal AnomalyArthralgiaInjuryPulmonary EmbolismVomitingDizzinessWeight Decreased
Premature BabyTachycardiaDeep Vein ThrombosisDeep Vein ThrombosisDyspnoeaVomitingDyspnoea
Maternal Drugs Affecting FoetusMydriasisGallbladder DisorderWeight IncreasedHeadacheMyocardial InfarctionDizziness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Synthroid and Metformin?

Get connected! Join a related mobile support group:
- support group for people who take Synthroid and Metformin
- support group for people who take Metformin
- support group for people who take Synthroid

Comments from related studies:

  • From this study (6 days ago):

  • I need to find a medicine in replace of my metforminso it doesn't affect my thyroid.

    Reply

  • From this study (3 weeks ago):

  • My WBC count has been low for 4mos now. I'm lethargic, having problems sleeping & still experiencing a tremendous amount of pain (which I believe it has to do with the congenital lipoma on my brain stem-I've had excruciating pain as long as I can remember.)

    Reply

    really? on Sep, 22, 2014:

    I honestly thought this was a board where we could all learn from
    Each other's experiences. Unfortunately, everyone seems to be fixated on this one poster, asking a question for a "friend" & who is supposedly mixing all types of drugs. Let's get off of the 3rd party bashing because anyone on all of those drugs needs a lot more than people on a web page. Geez!!!!

    Reply

  • From this study (4 weeks ago):

  • The extremely red arms and face looks like a sunburn.

    Reply

Post a new comment    OR    Read more comments

Can you answer these questions (what is this?):

  • Could prilosec cause an elevated blood sugar
    I've been on Prilosec for about 1 month & my blood sugars have been elevated starting shortly after I started on it. could Prilosec be causing it? Nothing else has changed with my meds or lifestyle.

  • Can cold sores cause bs to elevate?
    type 2 non insulin dependent DM. Having severe flu like symptoms when I get cold sore. BS never out of normal range except when I get cold sores!

  • I use levothroxine can i develop overactive bladder with continued use?
    I seeing A new doctor about 5 years ago. The drug I had been using before was from an animal source. New doctor prescribes Levothyroxine and I began taking it as prescribed and gradually the frequency and volume of urine increased until I would get up from sleep in the middle of my sleep cycle to ...

More questions for: Metformin, Synthroid

You may be interested at these reviews (what is this?):

  • Double vision on levothyroxine
    Diagnosed with under active thyroid in January 2011. Noticed onset of double vision in January 2014. Blurred vision and double vision worsened to such an extent that my glasses prescription has changed three times in less than 7 months. All the symptons I experience are a direct result of taking Le ...

  • I switched to armour ,it's not synthetic.
    I went off after 7 years on it when I discovered a link to a higher rate of lung cancer. I switched to Armour and it handled the hypothyroidism way better. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765368/

  • High blood pressure - find the right medication
    I was going through the menopause with all the usual drama when I started feeling awful. Doc said that my blood pressure was through the roof and prescribed Lisinopril. This gave me technicolour dreams and a runny nose, so he switched me to Losartan. This made me soooo tired that I didn't want to ...

More reviews for: Metformin, Synthroid

Complete drug side effects:

On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Metformin (metformin hydrochloride) is often used to treat type 2 diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

 

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