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Home > Synthroid > Metformin > Synthroid and Metformin

Review: Synthroid and Metformin

This review analyzes the effectiveness and drug interactions between Synthroid and Metformin. It is created by eHealthMe based on reports of 11,983 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Synthroid and Metformin >>>

What are the drugs

Synthroid (latest outcomes from 93,730 users) has active ingredients of levothyroxine sodium. It is often used in hypothyroidism.

Trend of synthroid reports

Metformin (latest outcomes from 100,884 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.

Trend of metformin reports

On Oct, 28, 2014: 11,983 people who take Synthroid, Metformin are studied

Synthroid, Metformin outcomes

Drug combinations in study:
- Synthroid (levothyroxine sodium)
- Metformin (metformin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Synthroid is effective18.18%
(2 of 11 people)
26.19%
(11 of 42 people)
43.33%
(13 of 30 people)
36.73%
(18 of 49 people)
60.64%
(57 of 94 people)
70.83%
(68 of 96 people)
69.41%
(118 of 170 people)
100.00%
(2 of 2 people)
Metformin is effective22.73%
(5 of 22 people)
22.97%
(17 of 74 people)
39.53%
(17 of 43 people)
29.87%
(23 of 77 people)
43.27%
(45 of 104 people)
55.68%
(49 of 88 people)
36.92%
(24 of 65 people)
25.00%
(1 of 4 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaFatigueHypoplastic Left Heart SyndromePainCholecystitis ChronicAnxietyFatigueNausea
Intentional OverdoseNauseaGestational DiabetesNauseaAnxietyFatigueMetabolic AcidosisBlood Glucose Increased
DiarrhoeaDyspnoeaMaternal Exposure During PregnancyChest PainPainDizzinessHyperkalaemiaFatigue
Blood Glucose IncreasedDizzinessInfectious PeritonitisAnxietyNauseaLactic AcidosisRenal Failure AcuteWeight Decreased
Cardiac ArrestDiarrhoeaOvarian CystDyspnoeaAbdominal Pain UpperRenal Failure AcuteDizzinessDiarrhoea
HypotensionVomitingFatigueSomnolenceCholelithiasisPulmonary EmbolismHigh Blood SugarPain
PainAbdominal PainWeight IncreasedCholecystitis ChronicWeight DecreasedSudden DeathNauseaDyspnoea
Suicide AttemptEmotional DistressAnxietyBlood Glucose IncreasedFatigueDeep Vein ThrombosisElectrocardiogram Pr ProlongationVomiting
Pancreatitis AcutePainDepressionFatigueDyspnoeaDepressionPainHeadache
Lip SwellingInsomniaPainFeeling ColdHypocalcaemiaThyroid Function Test AbnormalAnxietyDizziness

Drug effectiveness by gender :

FemaleMale
Synthroid is effective57.21%
(234 of 409 people)
63.86%
(53 of 83 people)
Metformin is effective37.06%
(146 of 394 people)
42.68%
(35 of 82 people)

Most common drug interactions by gender * :

FemaleMale
NauseaBlood Glucose Increased
Blood Glucose IncreasedMyocardial Infarction
FatigueNausea
PainRenal Failure Acute
Weight DecreasedWeight Decreased
DiarrhoeaAsthenia
VomitingDiarrhoea
DyspnoeaCardiac Failure Congestive
HeadacheFatigue
DizzinessDyspnoea

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Synthroid is effectiven/an/a0.00%
(0 of 10 people)
25.45%
(14 of 55 people)
35.09%
(40 of 114 people)
28.57%
(48 of 168 people)
35.68%
(86 of 241 people)
38.98%
(99 of 254 people)
Metformin is effectiven/an/a0.00%
(0 of 6 people)
9.62%
(5 of 52 people)
28.30%
(30 of 106 people)
22.62%
(38 of 168 people)
22.22%
(54 of 243 people)
21.26%
(54 of 254 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Transposition Of The Great Vesselsn/aNauseaCholecystitis ChronicPainNauseaNauseaNausea
Type 2 Diabetes MellitusVomitingAnxietyNauseaDiabetes MellitusBlood Glucose IncreasedFatigue
Blood Cholesterol IncreasedCholelithiasisCholelithiasisAnxietyType 2 Diabetes MellitusWeight DecreasedBlood Glucose Increased
Ventricular Septal DefectCholecystitis ChronicPainType 2 Diabetes MellitusWeight DecreasedDiarrhoeaDiarrhoea
Acquired Tracheo-oesophageal FistulaHeadacheAbdominal Pain UpperChest PainDiarrhoeaHeadachePain
Cardiac MurmurAbdominal Pain UpperAbdominal PainHeadacheBlood Glucose IncreasedDyspnoeaAsthenia
Oesophageal AtresiaGallbladder CholesterolosisNauseaDiabetes MellitusPainAstheniaVomiting
Congenital Musculoskeletal AnomalyArthralgiaInjuryPulmonary EmbolismVomitingDizzinessWeight Decreased
Premature BabyTachycardiaDeep Vein ThrombosisDeep Vein ThrombosisDyspnoeaVomitingDyspnoea
Maternal Drugs Affecting FoetusMydriasisGallbladder DisorderWeight IncreasedHeadacheMyocardial InfarctionDizziness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Synthroid and Metformin?

You are not alone! Join a related mobile support group:
- support group for people who take Synthroid and Metformin
- support group for people who take Metformin
- support group for people who take Synthroid

Can you answer these questions (Ask a question):

  • Could fenofibrate cause extreme vaginal irritation?
    (Asked by a 72 year old woman who has Itching,burning Of External Vaginal Area., and takes Levothyroxine Sodium, Fenofibrate)
    might possibly be pre-diabetic...Dr checks blood sugar every 6 mo.

  • Hallucinations and skin thas red and hurts
    (Asked by a 46 year old woman who has Hallucinations.skin Thats Red Like A Sun Burn And Mouth Blisters, and takes Hydrochlorothiazide, Sudafed, Levothyroxine Thyroid)
    I am having horrable hallucinations.manic episodes because i slam on the brakes to avoid people or animals that are not there.i feel like im going to razy.high bood pressure, heavy breathing and anxiety.my face and body have spoys that are like a sun burn and blisters in my mouth.emergency room accu ...

  • Is it okay to take co enzyme q 10 with levothyroxine
    (Asked by a 66 year old woman who has Hypothyroidism, and takes Levothyroxine Sodium)
    Is it okay to take Co Enzyme Q10 with Lovothyroxine. Will it stop my Levothyroxine from working properly. I am also on Simvastaton. Would appreciate any advice on this.

  • What drugs cause male breast enlargement
    (Asked by a 62 year old man who has Hydrocele, Breast Enlargement, and takes Hydrochlorothiazide, Metformin)
    At age 62 breast seam to enlarge over the last two years

  • How to deal with low blood pressure caused by metformin
    (Asked by a 75 year old man who has Low Blood Pressure, and takes Metformin)
    I was on Accupril 5 mg for more than 10 years with little or no side effects. I was diagnosed with early Type 2 diabetes and the doctor prescribed Metformin 500 mg 2 tablets a day. After about 3 months, the blood pressure was too low 88 Sistolic 45 diastolic and suffered syncope. I reduced Accupr ...

More questions for: Metformin, Synthroid

You may be interested at these reviews (Write a review):

  • Hair loss with metformin hydrochloride usage
    (Posted by a 58 year old woman who has Hair Loss, and takes Metformin Hydrochloride)
    I have been taking the drug Metformin Hydrochloride for about 5 months and definitely find that I am losing hair which is a problem I have never experienced. Always had the healthiest hair, no problems. Well, I am finding that I am losing lair significantly and feel that the manufacturer of this dru ...

  • Ranexa and erectile dysfunction
    (Posted by a 67 year old man who has Metabolic Syndrome, Aortic Valve Replacement, Coronary Artery Disease, and takes Nitrostat, Acyclovir, Gabapentin, Hytrin, Metformin, Aspirin, Isosorbide Mononitrate, Ranexa, Hydrochlorothiazide, Carvedilol, Losartan Potassium)
    I have experienced moderate ED with taking multiple heart and NO meds. This has been manageable and acceptable. Cardiologist added Ranexa (Ranalozine) 3 weeks ago and I am now experiencing complete erectile and ejaculatory failure.

  • Victoza and liver cancer (cholangiocarcinoma)
    (Posted by a 59 year old man who has Anaemia Vitamin B12 Deficiency, Sleep Apnea, Hypertension, Type 2 Diabetes Mellitus, Cholangiocarcinoma (liver Cancer), and takes Diovan, Atenolol, Metformin, Victoza)
    My husband was recently diagnosed with stage 4 liver cancer after taking Victoza for several years. The doctor discontinued the Victoza when the cancer was diagnosed but he actually started feeling better after he stopped it until the cancer started progressing. Since cholangiocarcinoma nd pancreati ...

  • Synthroid and breast enlargement
    (Posted by a 61 year old woman who has Breast Swelling, Breast Enlargement, and takes Synthroid)
    I have went from a B-C cup size to a D cup in the past 8-9 months.

  • Double vision on levothyroxine
    (Posted by a 49 year old woman who has Joint Stiffness, Lack Of Strength, Muscle Weakness, Weakness, Itching, Allergy To Food, Allergy To Chemicals, Fatigue - Chronic, Confusional State, Hair Loss, Double Vision, and takes Levothyroxine Sodium)
    Diagnosed with under active thyroid in January 2011. Noticed onset of double vision in January 2014. Blurred vision and double vision worsened to such an extent that my glasses prescription has changed three times in less than 7 months. All the symptons I experience are a direct result of taking Le ...

More reviews for: Metformin, Synthroid

Complete drug side effects:

On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Metformin (metformin hydrochloride) is often used to treat type 2 diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Metformin, Synthroid

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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