Review: Synthroid and Metformin
This review analyzes the effectiveness and drug interactions between Synthroid and Metformin. It is created by eHealthMe based on reports of 11,983 people who take the same drugs from FDA and social media, and is updated regularly.
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What are the drugs
Synthroid (latest outcomes from 93,730 users) has active ingredients of levothyroxine sodium. It is often used in hypothyroidism.
Metformin (latest outcomes from 100,884 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.
On Oct, 28, 2014: 11,983 people who take Synthroid, Metformin are studied
Drug combinations in study:
- Synthroid (levothyroxine sodium)
- Metformin (metformin hydrochloride)
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Synthroid is effective||18.18%|
(2 of 11 people)
(11 of 42 people)
(13 of 30 people)
(18 of 49 people)
(57 of 94 people)
(68 of 96 people)
(118 of 170 people)
(2 of 2 people)
|Metformin is effective||22.73%|
(5 of 22 people)
(17 of 74 people)
(17 of 43 people)
(23 of 77 people)
(45 of 104 people)
(49 of 88 people)
(24 of 65 people)
(1 of 4 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Nausea||Fatigue||Hypoplastic Left Heart Syndrome||Pain||Cholecystitis Chronic||Anxiety||Fatigue||Nausea|
|Intentional Overdose||Nausea||Gestational Diabetes||Nausea||Anxiety||Fatigue||Metabolic Acidosis||Blood Glucose Increased|
|Diarrhoea||Dyspnoea||Maternal Exposure During Pregnancy||Chest Pain||Pain||Dizziness||Hyperkalaemia||Fatigue|
|Blood Glucose Increased||Dizziness||Infectious Peritonitis||Anxiety||Nausea||Lactic Acidosis||Renal Failure Acute||Weight Decreased|
|Cardiac Arrest||Diarrhoea||Ovarian Cyst||Dyspnoea||Abdominal Pain Upper||Renal Failure Acute||Dizziness||Diarrhoea|
|Hypotension||Vomiting||Fatigue||Somnolence||Cholelithiasis||Pulmonary Embolism||High Blood Sugar||Pain|
|Pain||Abdominal Pain||Weight Increased||Cholecystitis Chronic||Weight Decreased||Sudden Death||Nausea||Dyspnoea|
|Suicide Attempt||Emotional Distress||Anxiety||Blood Glucose Increased||Fatigue||Deep Vein Thrombosis||Electrocardiogram Pr Prolongation||Vomiting|
|Lip Swelling||Insomnia||Pain||Feeling Cold||Hypocalcaemia||Thyroid Function Test Abnormal||Anxiety||Dizziness|
Drug effectiveness by gender :
|Synthroid is effective||57.21%|
(234 of 409 people)
(53 of 83 people)
|Metformin is effective||37.06%|
(146 of 394 people)
(35 of 82 people)
Most common drug interactions by gender * :
|Nausea||Blood Glucose Increased|
|Blood Glucose Increased||Myocardial Infarction|
|Pain||Renal Failure Acute|
|Weight Decreased||Weight Decreased|
|Dyspnoea||Cardiac Failure Congestive|
Drug effectiveness by age :
|Synthroid is effective||n/a||n/a||0.00%|
(0 of 10 people)
(14 of 55 people)
(40 of 114 people)
(48 of 168 people)
(86 of 241 people)
(99 of 254 people)
|Metformin is effective||n/a||n/a||0.00%|
(0 of 6 people)
(5 of 52 people)
(30 of 106 people)
(38 of 168 people)
(54 of 243 people)
(54 of 254 people)
Most common drug interactions by age * :
|Transposition Of The Great Vessels||n/a||Nausea||Cholecystitis Chronic||Pain||Nausea||Nausea||Nausea|
|Type 2 Diabetes Mellitus||Vomiting||Anxiety||Nausea||Diabetes Mellitus||Blood Glucose Increased||Fatigue|
|Blood Cholesterol Increased||Cholelithiasis||Cholelithiasis||Anxiety||Type 2 Diabetes Mellitus||Weight Decreased||Blood Glucose Increased|
|Ventricular Septal Defect||Cholecystitis Chronic||Pain||Type 2 Diabetes Mellitus||Weight Decreased||Diarrhoea||Diarrhoea|
|Acquired Tracheo-oesophageal Fistula||Headache||Abdominal Pain Upper||Chest Pain||Diarrhoea||Headache||Pain|
|Cardiac Murmur||Abdominal Pain Upper||Abdominal Pain||Headache||Blood Glucose Increased||Dyspnoea||Asthenia|
|Oesophageal Atresia||Gallbladder Cholesterolosis||Nausea||Diabetes Mellitus||Pain||Asthenia||Vomiting|
|Congenital Musculoskeletal Anomaly||Arthralgia||Injury||Pulmonary Embolism||Vomiting||Dizziness||Weight Decreased|
|Premature Baby||Tachycardia||Deep Vein Thrombosis||Deep Vein Thrombosis||Dyspnoea||Vomiting||Dyspnoea|
|Maternal Drugs Affecting Foetus||Mydriasis||Gallbladder Disorder||Weight Increased||Headache||Myocardial Infarction||Dizziness|
* Some reports may have incomplete information.
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You are not alone! Join a related mobile support group:
- support group for people who take Synthroid and Metformin
- support group for people who take Metformin
- support group for people who take Synthroid
Can you answer these questions (Ask a question):
- Could fenofibrate cause extreme vaginal irritation?
(Asked by a 72 year old woman who has Itching,burning Of External Vaginal Area., and takes Levothyroxine Sodium, Fenofibrate)
might possibly be pre-diabetic...Dr checks blood sugar every 6 mo.
- Hallucinations and skin thas red and hurts
(Asked by a 46 year old woman who has Hallucinations.skin Thats Red Like A Sun Burn And Mouth Blisters, and takes Hydrochlorothiazide, Sudafed, Levothyroxine Thyroid)
I am having horrable hallucinations.manic episodes because i slam on the brakes to avoid people or animals that are not there.i feel like im going to razy.high bood pressure, heavy breathing and anxiety.my face and body have spoys that are like a sun burn and blisters in my mouth.emergency room accu ...
- Is it okay to take co enzyme q 10 with levothyroxine
(Asked by a 66 year old woman who has Hypothyroidism, and takes Levothyroxine Sodium)
Is it okay to take Co Enzyme Q10 with Lovothyroxine. Will it stop my Levothyroxine from working properly. I am also on Simvastaton. Would appreciate any advice on this.
- What drugs cause male breast enlargement
(Asked by a 62 year old man who has Hydrocele, Breast Enlargement, and takes Hydrochlorothiazide, Metformin)
At age 62 breast seam to enlarge over the last two years
- How to deal with low blood pressure caused by metformin
(Asked by a 75 year old man who has Low Blood Pressure, and takes Metformin)
I was on Accupril 5 mg for more than 10 years with little or no side effects. I was diagnosed with early Type 2 diabetes and the doctor prescribed Metformin 500 mg 2 tablets a day. After about 3 months, the blood pressure was too low 88 Sistolic 45 diastolic and suffered syncope. I reduced Accupr ...
You may be interested at these reviews (Write a review):
- Hair loss with metformin hydrochloride usage
(Posted by a 58 year old woman who has Hair Loss, and takes Metformin Hydrochloride)
I have been taking the drug Metformin Hydrochloride for about 5 months and definitely find that I am losing hair which is a problem I have never experienced. Always had the healthiest hair, no problems. Well, I am finding that I am losing lair significantly and feel that the manufacturer of this dru ...
- Ranexa and erectile dysfunction
(Posted by a 67 year old man who has Metabolic Syndrome, Aortic Valve Replacement, Coronary Artery Disease, and takes Nitrostat, Acyclovir, Gabapentin, Hytrin, Metformin, Aspirin, Isosorbide Mononitrate, Ranexa, Hydrochlorothiazide, Carvedilol, Losartan Potassium)
I have experienced moderate ED with taking multiple heart and NO meds. This has been manageable and acceptable. Cardiologist added Ranexa (Ranalozine) 3 weeks ago and I am now experiencing complete erectile and ejaculatory failure.
- Victoza and liver cancer (cholangiocarcinoma)
(Posted by a 59 year old man who has Anaemia Vitamin B12 Deficiency, Sleep Apnea, Hypertension, Type 2 Diabetes Mellitus, Cholangiocarcinoma (liver Cancer), and takes Diovan, Atenolol, Metformin, Victoza)
My husband was recently diagnosed with stage 4 liver cancer after taking Victoza for several years. The doctor discontinued the Victoza when the cancer was diagnosed but he actually started feeling better after he stopped it until the cancer started progressing. Since cholangiocarcinoma nd pancreati ...
- Synthroid and breast enlargement
(Posted by a 61 year old woman who has Breast Swelling, Breast Enlargement, and takes Synthroid)
I have went from a B-C cup size to a D cup in the past 8-9 months.
- Double vision on levothyroxine
(Posted by a 49 year old woman who has Joint Stiffness, Lack Of Strength, Muscle Weakness, Weakness, Itching, Allergy To Food, Allergy To Chemicals, Fatigue - Chronic, Confusional State, Hair Loss, Double Vision, and takes Levothyroxine Sodium)
Diagnosed with under active thyroid in January 2011. Noticed onset of double vision in January 2014. Blurred vision and double vision worsened to such an extent that my glasses prescription has changed three times in less than 7 months. All the symptons I experience are a direct result of taking Le ...
Complete drug side effects:
On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Metformin (metformin hydrochloride) is often used to treat type 2 diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Synthroid is used in:
- Metformin is used in:
Other drugs that are used to treat the same conditions:
- Synthroid alternatives:
- Metformin alternatives:
Recent related drug studies (Check your drugs):
- A study of drug interactions between Mucinex D, Mobic, Gotu Kola, Humira, Levothyroxine Sodium, Singulair for a patient with Sinusitis, Joint Pain, Foot, Leg, And Ankle Swelling, Crohns, Hypothyroidism, Sinus Polyp. The patient has Pain - Joints, Joint Warmth, Swelling Of A Joint
Comments: the joint pain isn't as bad as the swelling!!! its been random & moves from joint to joint...my hands & fingers more severe...ive never had these symptoms before!! my doctor has run RA panels, MS panels etc...waiting on results!! started me on Mobic.....absolutely cant tell ive taken anything...no s ...
- A study of side effects of Tirosint for a patient with Hypothyroidism. The patient has Brain Stem Glioma (cancerous glioma tumour in the brainstem), Ringing In The Ears (a ringing in the ears), Vertigo - Positional (disorder arising in the inner ear cause vertigo)
Comments: I had a radiation treatment 2 summers ago to stop the function of my thyroid due to Grave's dis ease (HYPERTHYROIDISM). I went from brand name synthroidown to a generic version they was switched by my doctor to Tirosint in June 2014. I noticed mild dizziness only occasionally until about a month ago ...
- A study of drug interactions between Excedrin, Levothyroxine Sodium, Pentasa, Cymbalta for a patient with Migraine, Hypothyroidism, Crohn's Disease, Depression. The patient has Cough Aggravated, Indigestion, Stomach Discomfort, Crohn's Disease, Ulcerative Colitis, Tremor, Hair Loss, Difficulty Breathing, Sore Throat, Choking
Comments: Jan 2014 CDiff, mucus in stool, very weak sick, stool incontinence 3-4 times a day. Had been on most meds since March 2014 after diagnosis of UC/Crohn's/Proctitis, in July I started to loose my hair in handfulls. I was diagnosed with hypothyroidism. I started shaking a lot and noticed facial tremors ...
- A study of drug interactions between Ginkgo Biloba, Iron EDTA, Vitamin D, B12, Multivitamin, Metformin, Furosemide, Captopril, Carvedilol for a patient with Memory Loss, Low Blood Sugar, Iga Deficiency, Enzyme Supplementation, Diabetes, Hypertension - Essential, Hypertension. The patient has Confusion, Memory Loss
Comments: I lost a lot of time during a 9 month period, I can't remember what I said or did. I'm being brought up on charges of writing prescription medications after my Controlled License expired. I forgot to renew it. My husband thinks that I've lost it. I couldn't remember how to do the simplest things. I ...
- A study of drug interactions between Prilosec, Ativan, Vicodin, Naprosyn, Norpramin, Metformin, Robinul, Strattera, Wellbutrin, Flexeril, Lexapro for a patient with Reflux Gastritis, Anxiety, Pain, Arthritis, Depression, Weight Gain, Sweating - Excessive, To Treat Side Effects Of Antidepressants Such As Extreme Fatigue And Inability To Focus, To Treat Weight Gain Side Effects Of Anti Depressants. The patient has Swallowing Painful, Vision Blurred, Anxiety, Oral Pain, Angular Cheilitis, Taste Disturbance, Gum Pain, Tongue Exfoliation, Tongue Irritation, Headache - Migraine Without Aura, Sweating - Excessive, Pain - Muscles, Pain - Joints, Depression, Hair Loss
Comments: Naprosyn, Vicodin, Ativan and Prilosec are taken only on an as needed basis. Some of my symptoms are intermittent, and some are chronic. The though the medications may not completely rid me of a symptom (for example, depression or muscle pain), they do improve my condition enough to warrant their co ...
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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