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Review: taking Synthroid and Probiotic together

Summary: drug interactions are reported among people who take Synthroid and Probiotic together.

This review analyzes the effectiveness and drug interactions between Synthroid and Probiotic. It is created by eHealthMe based on reports of 143 people who take the same drugs from FDA and social media, and is updated regularly.


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On Apr, 13, 2015: 143 people who take Synthroid, Probiotic are studied

Synthroid, Probiotic outcomes

Drug combinations in study:
- Synthroid (levothyroxine sodium)
- Probiotic (bacillus coagulans)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Synthroid is effective0.00%
(0 of 1 people)
(1 of 3 people)
(1 of 2 people)
(3 of 5 people)
(3 of 6 people)
Probiotic is effectiven/a0.00%
(0 of 1 people)
(1 of 2 people)
(2 of 4 people)
(3 of 7 people)
(1 of 1 people)

Drug effectiveness by gender :

Synthroid is effective53.33%
(8 of 15 people)
(0 of 2 people)
Probiotic is effective38.46%
(5 of 13 people)
(2 of 2 people)

Drug effectiveness by age :

Synthroid is effectiven/an/a0.00%
(0 of 1 people)
(0 of 5 people)
(4 of 9 people)
(2 of 15 people)
(2 of 11 people)
Probiotic is effectiven/an/a0.00%
(0 of 1 people)
(0 of 5 people)
(3 of 9 people)
(3 of 7 people)
(1 of 10 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Oedema PeripheralBronchial DisorderMetallic TasteJoint SwellingTesticular MassNight SweatsArthritisFatigue
PyrexiaVascular CalcificationFatigueTinnitusFatigueTesticular MassFibromyalgiaNausea
Musculoskeletal StiffnessChest DiscomfortNasal UlcerPain - JointsNight SweatsVertigoHypersomniaHypotension
MyalgiaCoughConstipationHypermobile JointsArthritisSkin - DryInsomniaDiarrhoea
Muscular WeaknessSensation Of Foreign BodyHigh Blood Cholesterol And TriglyceridesVertigoLightheadednessHeadache - Mixed Tension MigraineRash Erythematous
ChillsPruritusDepressive SymptomAnal StenosisDiarrhoeaChronic SinusitisDyspnoea
Activities Of Daily Living ImpairedWheezingAcid RefluxDegenerative Joint DiseaseNerve PainPain ExacerbatedBlood Uric Acid Increased
PancreatitisFatigueScoliosisShortness Of BreathRheumatoid Factor PositivePain
AstheniaNasal UlcerInsomniaHigh Blood Cholesterol And TriglyceridesAspartate Aminotransferase Increased
ArthropathyPancreatitisRheumatoid Factor PositiveVascular CalcificationAlanine Aminotransferase Increased

Most common drug interactions by gender * :

DiarrhoeaTransient Ischaemic Attack
HypotensionVisual Impairment
PainAtrial Fibrillation
Blood Uric Acid IncreasedPruritus
Rash ErythematousTesticular Mass
Aspartate Aminotransferase IncreasedThroat Irritation
Alanine Aminotransferase IncreasedNight Sweats

Most common drug interactions by age * :

n/an/aFatiguen/aInjection Site PainPainDrug IneffectiveFatigue
Crohn's DiseaseIntervertebral Disc ProtrusionPainHypotension
NauseaPain In ExtremityArthralgiaBlood Uric Acid Increased
Diarrhoea HaemorrhagicMalaiseFeeling AbnormalRash Erythematous
VomitingNeuralgiaDepressionAspartate Aminotransferase Increased
Injection Site ErythemaGait DisturbanceArthritisDiarrhoea
MalaiseAnxietyFlushingAlanine Aminotransferase Increased
FatigueDyspnoeaNight SweatsOedema Peripheral
TachycardiaNauseaTesticular MassRash Macular
HyperhidrosisPulmonary Arterial HypertensionNeutropeniaAsthenia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Do you take Synthroid and Probiotic?




You are not alone! Join a related support group:
- support group for people who take Probiotic
- support group for people who take Synthroid

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Probiotic (bacillus coagulans) is often used to treat irritable bowel syndrome. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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