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Review: taking Taxol and Benadryl together

Summary: drug interactions are reported among people who take Taxol and Benadryl together.

This review analyzes the effectiveness and drug interactions between Taxol and Benadryl. It is created by eHealthMe based on reports of 3,100 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 6, 2015: 3,100 people who take Taxol, Benadryl are studied

Taxol, Benadryl outcomes

Drug combinations in study:
- Taxol (paclitaxel)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Taxol is effectiven/a100.00%
(2 of 2 people)
Benadryl is effectiven/a100.00%
(3 of 3 people)

Drug effectiveness by gender :

Taxol is effective100.00%
(2 of 2 people)
Benadryl is effective100.00%
(3 of 3 people)

Drug effectiveness by age :

Taxol is effectiven/an/an/an/an/an/a100.00%
(1 of 1 people)
(1 of 6 people)
Benadryl is effectiven/an/an/an/an/a50.00%
(1 of 2 people)
(1 of 1 people)
(1 of 6 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DyspnoeaAnaemiaHypertensionTransient Ischaemic AttackHeadacheVomitingn/aHypersensitivity Nos
NauseaDehydrationNauseaGastrointestinal DisorderHypoaesthesiaNauseaNausea
PyrexiaPleural EffusionMalnutrition NosRenal PainVision BlurredConstipationDyspnoea
HypersensitivityAnxietyHypokalaemiaBone PainDysarthriaPyrexia
DehydrationFallSepsis NosArthralgiaMental Status ChangesAnaemia
VomitingErythemaDiarrhoea NosLupus-like SyndromeFallPain
NeutropeniaNauseaDehydrationMalaiseDepressed Level Of ConsciousnessBack Pain
Hypersensitivity NosPain In JawChest PainMyocardial IschaemiaGait DisturbanceChest Pain
White Blood Cell Count DecreasedSinus TachycardiaParaesthesiaAmnesiaMeningeal NeoplasmDyspnoea Nos
Malignant Neoplasm ProgressionBone DisorderContusionOvarian CancerVomitingAnxiety

Most common drug interactions by gender * :

DyspnoeaDyspnoea Nos
Hypersensitivity NosDehydration
AnaemiaHypersensitivity Nos
AnxietyChest Pain
Pain In JawDyspnoea
Osteonecrosis Of JawPneumonia

Most common drug interactions by age * :

n/an/aNauseaNauseaAnaemiaPain In JawNauseaNausea
NeutropeniaTooth ExtractionIntervertebral Disc ProtrusionTooth ExtractionAnaemiaPyrexia
SyncopeWound TreatmentOsteoarthritisAnxietySwellingDehydration
TachycardiaOsteonecrosisMood SwingsErythemaBone DisorderHypersensitivity Nos
DizzinessAbdominal Pain NosWeight IncreasedBone DisorderVomitingPneumonia
AstheniaHepatomegalyDyspnoeaNauseaImpaired HealingHypotension
Cardiac ArrestRashToothacheImpaired HealingPain In JawDyspnoea Nos
Nephrogenic Systemic FibrosisAnaphylactoid ReactionPyrexiaChest PainOsteonecrosis Of JawBack Pain
PneumonitisSwelling FaceRash ErythematousDepressionPleural EffusionPleural Effusion

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Taxol and Benadryl?




You are not alone! Join a related mobile support group on :
- support group for people who take Benadryl
- support group for people who take Taxol

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Taxol (paclitaxel) is often used to treat breast cancer. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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