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Review: Taxol and Benadryl





Summary: drug interactions are reported among people who take Taxol and Benadryl together.

This review analyzes the effectiveness and drug interactions between Taxol and Benadryl. It is created by eHealthMe based on reports of 3,100 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Taxol and Benadryl >>>

What are the drugs

Taxol has active ingredients of paclitaxel. It is often used in breast cancer. (latest outcomes from Taxol 21,581 users)

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (view latest outcomes from 29,367 users)

On Nov, 28, 2014: 3,100 people who take Taxol, Benadryl are studied

Taxol, Benadryl outcomes

Drug combinations in study:
- Taxol (paclitaxel)
- Benadryl (diphenhydramine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Taxol is effectiven/a100.00%
(2 of 2 people)
n/an/an/an/an/an/a
Benadryl is effectiven/a100.00%
(3 of 3 people)
n/an/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DyspnoeaAnaemiaHypertensionTransient Ischaemic AttackHeadacheVomitingn/aHypersensitivity Nos
NauseaDehydrationNauseaGastrointestinal DisorderHypoaesthesiaNauseaNausea
PyrexiaPleural EffusionMalnutrition NosRenal PainVision BlurredConstipationDyspnoea
HypersensitivityAnxietyHypokalaemiaBone PainDysarthriaPyrexia
DehydrationFallSepsis NosArthralgiaMental Status ChangesAnaemia
VomitingErythemaDiarrhoea NosLupus-like SyndromeFallPain
NeutropeniaNauseaDehydrationMalaiseDepressed Level Of ConsciousnessBack Pain
Hypersensitivity NosPain In JawChest PainMyocardial IschaemiaGait DisturbanceChest Pain
White Blood Cell Count DecreasedSinus TachycardiaParaesthesiaAmnesiaMeningeal NeoplasmDyspnoea Nos
Malignant Neoplasm ProgressionBone DisorderContusionOvarian CancerVomitingAnxiety

Drug effectiveness by gender :

FemaleMale
Taxol is effective100.00%
(2 of 2 people)
n/a
Benadryl is effective100.00%
(3 of 3 people)
n/a

Most common drug interactions by gender * :

FemaleMale
NauseaPyrexia
DyspnoeaDyspnoea Nos
Hypersensitivity NosDehydration
AnaemiaHypersensitivity Nos
PainNausea
AnxietyChest Pain
Pain In JawDyspnoea
PyrexiaFlushing
Osteonecrosis Of JawPneumonia
VomitingHypotension

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Taxol is effectiven/an/an/an/an/an/a100.00%
(1 of 1 people)
16.67%
(1 of 6 people)
Benadryl is effectiven/an/an/an/an/a50.00%
(1 of 2 people)
100.00%
(1 of 1 people)
16.67%
(1 of 6 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aNauseaNauseaAnaemiaPain In JawNauseaNausea
HypotensionDyspnoeaPainPainDyspnoeaDyspnoea
NeutropeniaTooth ExtractionIntervertebral Disc ProtrusionTooth ExtractionAnaemiaPyrexia
SyncopeWound TreatmentOsteoarthritisAnxietySwellingDehydration
TachycardiaOsteonecrosisMood SwingsErythemaBone DisorderHypersensitivity Nos
DizzinessAbdominal Pain NosWeight IncreasedBone DisorderVomitingPneumonia
AstheniaHepatomegalyDyspnoeaNauseaImpaired HealingHypotension
Cardiac ArrestRashToothacheImpaired HealingPain In JawDyspnoea Nos
Nephrogenic Systemic FibrosisAnaphylactoid ReactionPyrexiaChest PainOsteonecrosis Of JawBack Pain
PneumonitisSwelling FaceRash ErythematousDepressionPleural EffusionPleural Effusion

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Taxol and Benadryl?

You are not alone! Join a related mobile support group:
- support group for people who take Taxol and Benadryl
- support group for people who take Benadryl
- support group for people who take Taxol

Can you answer these questions (Ask a question):

More questions for: Benadryl, Taxol

You may be interested at these reviews (Write a review):

  • Dyphenhydramine and headaches horrible going one almost 24 hours a day for 4 weeks and cant get them to stop, now looking for cause . think its the dyphenhydramine im taking to help me sleep .
    have been taking 3 dyphenhydramine for some time to help me sleep , just in last few weeks began having severe headache almost all the time.. cant get it to go away. just found out it can cause headache and am going to lower my intake to one per night and see if my headaches get better. am taking migrane meds and that hasnt helped a bit so think its not migranes im having. some other reason.
  • Nightmare on benadryl
    After 5 nights without sleep and not having past bad dreams, the last 2 night's taking walfrin sub, for benadryl has terrified THE WORST OF WORST dream in my 55 years. Peaceful start of a dream then seeing myself or family,friends get slottard.crazy thing is I don't watch scary movies or the news. I think I'm going to pass on this meds, and pass out next time :) thank you,God bless
  • Benadryl completed suicide 50 year old
    My mother comitted suicide by taking a bottle of Benadryl. She also had been drinking, she had taken xanax and drank beer, she also took 300 Benadryl pills and started having seizures and went to the hospital was brain dead and her heart stopped the next morning.
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
  • Leg pain and occasional arm and hand pain
    I started having leg pains at night, lower leg felt like the muscle and bone were being pulled causing sharp pain. It was relieved by getting up and walking but would last most of the night.

    I finally realized after suffering this over and over for months, that it only happened when I had taken benadryl.

    It seems that the benadryl causes it after taking it within one hour, I don't know why I didn't connect this until yesterday. Sometimes, more rarely, I also had arm and hand pain.

More reviews for: Benadryl, Taxol

Comments from related studies:

  • From this study (3 years ago):

  • Tceleste on Nov, 25, 2011:

    I became very agitated on taxol and carboplatin. I also take Ativan rarely. I take zofran, claritin and Neulasta. I take Mobic (meloxicam) and percocet for pain. I have continuously moved even when I am so tired I can barely chew. It is not a seizure type movement. I am either cleaning, organizing or planning to clean and organize. I feel as though I have been given a nesting hormone, when in fact all estrogen has been taken from me and I had both ovaries and my complete omentum removed. My son commented on me as well as several friends. The thing I think about is that for at least 2 and a half years I was very sick. By the time I was diagnosed I was already Stage IIIb. I feel like my old normal energy is returning since I had so much cancer removed by surgery and now the chemo is working because my hair is falling out, which to me is reassuring. I have to disclipine myself to rest and not be always organizing my house. I think the lady who helps me clean is going to fire me because by the time she gets here there is little to do. If I were not as disclipined as I am about making myself rest, this could be a bigger problem.

    Tceleste

    Reply

  • From this study (5 years ago):

  • diagnoised 1996, surgery + carboplatin/taxol(12)
    1997 - second look surgery, high dose chemo (cisplatin,cytoxin,thiotepa) -stemcell rescue,
    recurrance 2001- taxol + stint in ureter
    recurrance 2003 carboplatin(6) + telcyta(9) - clinical trial stable then tumor began growing
    2005 stable as managed with Lupron, Femora
    2008 tumor began growing - sugery + Doxil(24)
    2010 Taxol/Carboplatin(4 to date with significant response)

    Reply

Complete drug side effects:

On eHealthMe, Taxol (paclitaxel) is often used to treat breast cancer. Benadryl (diphenhydramine hydrochloride) is often used to treat allergies. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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