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Review: taking Tizanidine and Gabapentin together

Summary: drug interactions are reported among people who take Tizanidine and Gabapentin together. This review analyzes the effectiveness and drug interactions between Tizanidine and Gabapentin. It is created by eHealthMe based on reports of 2,390 people who take the same drugs from FDA and social media, and is updated regularly.

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What are the drugs

Tizanidine hydrochloride has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from 1,559 Tizanidine hydrochloride users)

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from 39,682 Gabapentin users)

On May, 4, 2015: 2,390 people who take Tizanidine Hydrochloride, Gabapentin are studied

Tizanidine Hydrochloride, Gabapentin outcomes

Drug combinations in study:
- Tizanidine Hydrochloride (tizanidine hydrochloride)
- Gabapentin (gabapentin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tizanidine Hydrochloride is effective25.00%
(3 of 12 people)
(4 of 22 people)
(4 of 21 people)
(8 of 21 people)
(9 of 18 people)
(3 of 9 people)
(3 of 4 people)
Gabapentin is effective18.18%
(2 of 11 people)
(6 of 25 people)
(1 of 11 people)
(2 of 16 people)
(11 of 28 people)
(3 of 10 people)
(3 of 5 people)

Drug effectiveness by gender :

Tizanidine Hydrochloride is effective32.56%
(28 of 86 people)
(6 of 20 people)
Gabapentin is effective27.91%
(24 of 86 people)
(4 of 20 people)

Drug effectiveness by age :

Tizanidine Hydrochloride is effectiven/an/an/a19.05%
(4 of 21 people)
(6 of 46 people)
(10 of 47 people)
(14 of 50 people)
(0 of 20 people)
Gabapentin is effectiven/an/an/a13.64%
(3 of 22 people)
(5 of 45 people)
(6 of 46 people)
(12 of 50 people)
(2 of 19 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Confusional StateMental DisorderAnxietyDehydrationPainDepressionBladder ProlapsePain
DizzinessPainEmotional DistressCholecystitis ChronicSuicide AttemptFatigueMuscle AtrophyAnxiety
SomnolenceAtelectasisInsomniaBreast CancerInsomniaSuicide AttemptOedemaDepression
FallDepressionDyspnoeaHeadacheAnxietyLoss Of ConsciousnessParaesthesiaFall
NauseaAnxietyDuodenal UlcerGeneral Physical Health DeteriorationRoad Traffic AccidentAnxietyAnorexiaDyspnoea
Loss Of ConsciousnessPulmonary EmbolismDehydrationPulmonary EmbolismDepressionHallucinationAdverse ReactionHeadache
Vision BlurredConfusionDrug Withdrawal SyndromePulmonary InfarctionOverdoseHip FractureBlood Pressure IncreasedNausea
Dry MouthPleural EffusionCushingoidLoss Of Sensation, Numbness And Tingling, Paresthesias, Sensory Loss, Tingling And NumbnessSuicidal IdeationIncontinenceSyncopeFatigue
Myocardial InfarctionHeadacheOedema PeripheralDeep Vein ThrombosisPulmonary EmbolismMemory ImpairmentActivities Of Daily Living ImpairedAsthenia
FatigueDysarthriaPalpitationsAnxietyHeadacheFallTremorDrug Ineffective

Most common drug interactions by gender * :

AnxietyBack Pain
DepressionMuscle Spasms
DyspnoeaDrug Dependence
AstheniaPain In Extremity
DizzinessConfusional State

Most common drug interactions by age * :

Epilepsyn/aSerotonin SyndromeAnxietyAnxietyPainPainPain
Drug Effect DecreasedConstipationCompleted SuicideNauseaDepressionDepressionFall
General Physical Health DeteriorationIleusDepressionArthralgiaAnxietyFallDyspnoea
Haemoglobin DecreasedDystoniaMuscle SpasmsPainHeadacheFatigueAnxiety
DiarrhoeaBlepharospasmConfusional StateHeadacheChest PainDyspnoeaHypotension
DehydrationPyrexiaMetabolic AcidosisDyspnoeaMuscle SpasmsAnxietyUrinary Tract Infection
Aspartate Aminotransferase IncreasedAccommodation DisorderHeadacheDrug Withdrawal SyndromeFallBack PainAsthenia
Blood Alkaline Phosphatase IncreasedUrinary Tract InfectionAstheniaNauseaHypertensionMyocardial Infarction
Blood Lactate Dehydrogenase IncreasedDrug IneffectiveDepressionDrug IneffectiveHeadacheConfusional State
BradycardiaNauseaFatigueAstheniaMemory ImpairmentOsteoarthritis

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Tizanidine and Gabapentin on

Do you take Tizanidine and Gabapentin?


You are not alone! Join a related support group:
- support group for people who take Gabapentin
- support group for people who take Tizanidine Hydrochloride

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Gabapentin, Tizanidine Hydrochloride

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More reviews for: Gabapentin, Tizanidine Hydrochloride

Comments from related studies:

  • From this study (1 month ago):

  • I have bladder leakage immediately after urination, just a bit but enougthat I have to use a panty liner


  • From this study (4 months ago):

  • coolaero on Feb, 7, 2015:

    there wont be side effect other that DEATH


    peanuts on Mar, 31, 2010:

    my friend is suffering from rhumatory arthertis.and is currenty taking cocaine. oxy cotin,prestine, wellbutrim, predisone 10mg what side effects should she expect ?????


Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Tizanidine Hydrochloride (tizanidine hydrochloride) is often used to treat muscle spasms. Gabapentin (gabapentin) is often used to treat neuralgia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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