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Home > Tizanidine > Methotrexate > Tizanidine and Methotrexate

Review: Tizanidine and Methotrexate

Summary: drug interactions are reported among people who take Tizanidine and Methotrexate together.

This review analyzes the effectiveness and drug interactions between Tizanidine and Methotrexate. It is created by eHealthMe based on reports of 307 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Tizanidine and Methotrexate >>>

What are the drugs

Tizanidine hydrochloride (latest outcomes from 1,530 users) has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms.

Trend of tizanidine hydrochloride reports

Methotrexate (latest outcomes from 131,185 users) has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis.

Trend of methotrexate reports

On Oct, 31, 2014: 307 people who take Tizanidine Hydrochloride, Methotrexate are studied

Tizanidine Hydrochloride, Methotrexate outcomes

Drug combinations in study:
- Tizanidine Hydrochloride (tizanidine hydrochloride)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tizanidine Hydrochloride is effectiven/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
0.00%
(0 of 5 people)
n/a100.00%
(1 of 1 people)
n/a
Methotrexate is effectiven/a0.00%
(0 of 3 people)
0.00%
(0 of 1 people)
n/a33.33%
(1 of 3 people)
100.00%
(1 of 1 people)
100.00%
(1 of 1 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
RhabdomyolysisJoint EffusionVulvovaginal PainInterstitial Lung DiseaseZygomycosisStomach Painn/aFall
AbasiaUterine CancerHerpes ZosterHypoxiaBlood Culture PositivePyrexia
Blood Creatine Phosphokinase IncreasedCholelithiasisGenital HerpesStomach PainUterine CancerArthralgia
HypersomniaDysuriaUrine Phosphate AbnormalJoint EffusionFatigue
FallImpaired Gastric EmptyingDysuriaPneumonia
AtelectasisLeukocytosisCholelithiasisPain
AnaemiaZygomycosisPainHypertension
HypertensionBlood Culture PositiveVocal Cord ParalysisNausea
CoughHaematomaCervix CarcinomaChest Pain
PneumoniaPneumoniaHeart Rate IncreasedBack Pain

Drug effectiveness by gender :

FemaleMale
Tizanidine Hydrochloride is effective20.00%
(1 of 5 people)
25.00%
(1 of 4 people)
Methotrexate is effective25.00%
(1 of 4 people)
40.00%
(2 of 5 people)

Most common drug interactions by gender * :

FemaleMale
FallPain Nos
PyrexiaPneumonia
FatigueSplenomegaly
ArthralgiaSepsis
PainMyalgia
NauseaParaplegia
HypertensionMultiple Sclerosis
PneumoniaInfluenza Like Illness
Back PainEmphysema
Chest PainRheumatoid Arthritis

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tizanidine Hydrochloride is effectiven/an/an/an/a100.00%
(1 of 1 people)
0.00%
(0 of 5 people)
50.00%
(1 of 2 people)
0.00%
(0 of 1 people)
Methotrexate is effectiven/an/an/an/a100.00%
(1 of 1 people)
0.00%
(0 of 6 people)
100.00%
(1 of 1 people)
100.00%
(1 of 1 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/aFaeces DiscolouredSubarachnoid HaemorrhageNauseaFallArthralgia
Weight DecreasedFibromyalgiaFatigueAnaemiaFall
HypokalaemiaPainIntervertebral DiscitisCoughAngiopathy
Biliary DyskinesiaSplenomegalyPainRhabdomyolysisPain Nos
CholesterosisSepsisArthralgiaPneumoniaHerpes Zoster
Cholecystitis ChronicHeadacheFallUrinary Tract InfectionHypochloraemia
Pain In ExtremityHypertensionHeadachePyrexiaMuscle Spasms
VomitingChest PainPain In ExtremityHypertensionMyalgia
Abdominal PainArthralgiaPyrexiaAbasiaOedema Peripheral
Abdominal Pain UpperRheumatoid ArthritisMalaiseAtelectasisHypokalaemia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tizanidine and Methotrexate?

You are not alone! Join a related mobile support group:
- support group for people who take Tizanidine and Methotrexate
- support group for people who take Methotrexate
- support group for people who take Tizanidine Hydrochloride

Recent conversations of related support groups:

Latest outcomes in real world:

Can you answer these questions (Ask a question):

More questions for: Methotrexate, Tizanidine Hydrochloride

You may be interested at these reviews (Write a review):

  • Humira: my experience
    (Posted by a 66 year old man who has Ankylosing Spondylitis, Reiter's Syndrome, Psoriatic Arthritis, and takes Methotrexate Preservative Free, Enbrel, Humira)
    I have had some form of arthritis probably since birth. My father and maternal grandfather had some form of arthritis. I began to realize pain in both ankles if I stood or walked too long. I began taking many NSAIDs when I was around 22. I've done gold, prednisone (twice), plaquenil, butazoidin, ...

  • Psoratic arthritis and trigeminal neuralgia
    (Posted by a 33 year old man who has Nasal Septum Deviation, Psoriasis, Psoriatic Arthritis, Trigeminal Neuralgia, Asthma Exercise Induced, and takes Methotrexate)
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic a ...

  • Spiriva caused me to swell up like a hippo.
    (Posted by a 46 year old woman who has Rheumatoid Arthritis, Irritable Bowel Syndrome, and takes Advair Diskus 250/50, Methotrexate, Plaquenil, Metformin, Klonopin, Zanaflex, Prednisone, Singulair, Imitrex, Nexium)
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen ...

  • Chills while on tizanidine
    (Posted by a 62 year old woman who has Chills, and takes Tizanidine Hydrochloride)
    Extremely sensitive to cold and have chills several times a day

  • Off label use of drugs for peripheral neuropathy causing memory loss
    (Posted by a 56 year old man who has Peripheral Neuropathy, and takes Pramipexole Dihydrochloride, Tizanidine Hydrochloride, Lyrica, Bupropion Hydrochloride, Savella, Methadone Hydrochloride, Axiron, Baby Aspirin, Senna, Colace, Oxcarbazepine, Gabapentin)
    I have peripheral neuropathy with standard symptoms of burning, tingling, stabbing pain on the tops of my feet. I have had this condition for over 15 years getting worse over time. The last 5 years I have seen a couple of doctors and through trial and error we settled on a combination of Savella and ...

More reviews for: Methotrexate, Tizanidine Hydrochloride

Complete drug side effects:

On eHealthMe, Tizanidine Hydrochloride (tizanidine hydrochloride) is often used to treat muscle spasms. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Methotrexate, Tizanidine Hydrochloride

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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