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Related topic: Methotrexate, Tizanidine Hydrochloride

Review: Tizanidine and Methotrexate

This review analyzes the effectiveness and drug interactions between Tizanidine and Methotrexate. It is created by eHealthMe based on 298 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

How are my drugs for patients like me? On eHealthMe, you can find the answer by studying 348 million drug outcomes from FDA and social media. Start now >>>

On Apr, 7, 2014: 298 people who reported to have interactions when taking Tizanidine Hydrochloride, Methotrexate are studied

Trend of Tizanidine Hydrochloride, Methotrexate's drug interactions, side effects and effectiveness reports (4899346)

Drug combinations in study:
- Tizanidine Hydrochloride (tizanidine hydrochloride)
- Methotrexate (methotrexate sodium)

eHealthMe real world results:

Most common interactions experienced by people in the use of Tizanidine Hydrochloride, Methotrexate:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Pyrexia (fever)111
Arthralgia (joint pain)99
Hypertension (high blood pressure)88
Fall88
Pain75
Fatigue (feeling of tiredness)64
Nausea (feeling of having an urge to vomit)60
Pneumonia59
Headache (pain in head)56
Chest Pain54

Most common interactions experienced by people in long term use of Tizanidine Hydrochloride, Methotrexate:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Lymphadenopathy (disease or enlargement of lymph nodes)6
Zygomycosis (an infection caused by fungus)6
Uterine Cancer6
Joint Effusion (presence of extra fluid in joint covering)4
Pericardial Effusion (fluid around the heart)4
Endocarditis (inflammation in heart muscle)4
Pneumonia4
Cervix Carcinoma (cancer of cervix)4
Heart Rate Increased4
Haematoma (collection of blood outside the blood vessels)4

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Tizanidine Hydrochloride0.00%0.00%100.00%0.00%0.00%
Methotrexate0.00%0.00%100.00%0.00%0.00%

Top conditions involved for these people * :

  1. Rheumatoid arthritis
  2. Pain
  3. Fibromyalgia
  4. Depression
  5. Colitis ulcerative

Top co-used drugs for these people * :

  1. Zanaflex
  2. Folic acid
  3. Golimumab
  4. Humira
  5. Tizanidine hcl

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Complete drug side effects:

On eHealthMe, Tizanidine Hydrochloride (tizanidine hydrochloride) is often used to treat muscle spasms. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (3 months ago):

  • I take methotexate weekly.. After a day of taking them, I have terrible chest pain that radiates to my neck, and down my sides

    Reply

Can you answer these questions (what is this?):

More questions for: Methotrexate, Tizanidine Hydrochloride

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  • Psoratic arthritis and trigeminal neuralgia
    hi i suffer from psorisis and psoratic athritis i was just diagnosed with trigeminal neuralgia i was looking for the connection between the two and i see that there is one from your study the thing is all 13 people in the study said to have psoriatic arthropathy yet only one said to have psoratic a ...

  • Spiriva caused me to swell up like a hippo.
    My Doctor prescribed spiriva to help me breathe due to asthma/cold. I never smoked but my parents and friends were heavy smokers. I used the spiriva 3 times. Once a day for 3 days then I started swelling in my ankles and the swelling continued until my face, hands arms... basically I was so swollen ...

  • Chills while on tizanidine
    Extremely sensitive to cold and have chills several times a day

More reviews for: Methotrexate, Tizanidine Hydrochloride

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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