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Review: taking Tizanidine and Methotrexate together

Summary: drug interactions are reported among people who take Tizanidine and Methotrexate together. This review analyzes the effectiveness and drug interactions between Tizanidine and Methotrexate. It is created by eHealthMe based on reports of 307 people who take the same drugs from FDA and social media, and is updated regularly.

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What are the drugs

Tizanidine hydrochloride has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from 1,559 Tizanidine hydrochloride users)

Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from 131,279 Methotrexate users)

On May, 13, 2015: 307 people who take Tizanidine Hydrochloride, Methotrexate are studied

Tizanidine Hydrochloride, Methotrexate outcomes

Drug combinations in study:
- Tizanidine Hydrochloride (tizanidine hydrochloride)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tizanidine Hydrochloride is effectiven/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
0.00%
(0 of 5 people)
n/a100.00%
(1 of 1 people)
n/a
Methotrexate is effectiven/a0.00%
(0 of 3 people)
0.00%
(0 of 1 people)
n/a33.33%
(1 of 3 people)
100.00%
(1 of 1 people)
100.00%
(1 of 1 people)
n/a

Drug effectiveness by gender :

FemaleMale
Tizanidine Hydrochloride is effective20.00%
(1 of 5 people)
25.00%
(1 of 4 people)
Methotrexate is effective25.00%
(1 of 4 people)
40.00%
(2 of 5 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tizanidine Hydrochloride is effectiven/an/an/an/a100.00%
(1 of 1 people)
0.00%
(0 of 5 people)
50.00%
(1 of 2 people)
0.00%
(0 of 1 people)
Methotrexate is effectiven/an/an/an/a100.00%
(1 of 1 people)
0.00%
(0 of 6 people)
100.00%
(1 of 1 people)
100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
RhabdomyolysisJoint EffusionVulvovaginal PainInterstitial Lung DiseaseZygomycosisStomach Painn/aFall
AbasiaUterine CancerHerpes ZosterHypoxiaBlood Culture PositivePyrexia
Blood Creatine Phosphokinase IncreasedCholelithiasisGenital HerpesStomach PainUterine CancerArthralgia
HypersomniaDysuriaUrine Phosphate AbnormalJoint EffusionFatigue
FallImpaired Gastric EmptyingDysuriaPneumonia
AtelectasisLeukocytosisCholelithiasisPain
AnaemiaZygomycosisPainHypertension
HypertensionBlood Culture PositiveVocal Cord ParalysisNausea
CoughHaematomaCervix CarcinomaChest Pain
PneumoniaPneumoniaHeart Rate IncreasedBack Pain

Most common drug interactions by gender * :

FemaleMale
FallPain Nos
PyrexiaPneumonia
FatigueSplenomegaly
ArthralgiaSepsis
PainMyalgia
NauseaParaplegia
HypertensionMultiple Sclerosis
PneumoniaInfluenza Like Illness
Back PainEmphysema
Chest PainRheumatoid Arthritis

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/aFaeces DiscolouredSubarachnoid HaemorrhageNauseaFallArthralgia
Weight DecreasedFibromyalgiaFatigueAnaemiaFall
HypokalaemiaPainIntervertebral DiscitisCoughAngiopathy
Biliary DyskinesiaSplenomegalyPainRhabdomyolysisPain Nos
CholesterosisSepsisArthralgiaPneumoniaHerpes Zoster
Cholecystitis ChronicHeadacheFallUrinary Tract InfectionHypochloraemia
Pain In ExtremityHypertensionHeadachePyrexiaMuscle Spasms
VomitingChest PainPain In ExtremityHypertensionMyalgia
Abdominal PainArthralgiaPyrexiaAbasiaOedema Peripheral
Abdominal Pain UpperRheumatoid ArthritisMalaiseAtelectasisHypokalaemia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Tizanidine and Methotrexate on

Do you take Tizanidine and Methotrexate?

 

You are not alone! Join a related support group:
- support group for people who take Methotrexate
- support group for people who take Tizanidine Hydrochloride

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Methotrexate, Tizanidine Hydrochloride

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More reviews for: Methotrexate, Tizanidine Hydrochloride

Comments from related studies:

  • From this study (10 months ago):

  • I recently quit taking all meds due to loss of insurance coverage. I have been having symptoms for a week that seem to only get worse

    Reply

  • From this study (1 year ago):

  • I take methotexate weekly.. After a day of taking them, I have terrible chest pain that radiates to my neck, and down my sides

    Reply

Complete drug side effects:

On eHealthMe, Tizanidine Hydrochloride (tizanidine hydrochloride) is often used to treat muscle spasms. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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