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Review: Tizanidine and Methotrexate

This review analyzes the effectiveness and drug interactions between Tizanidine and Methotrexate. It is created by eHealthMe based on reports of 306 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Tizanidine and Methotrexate >>>

What are the drugs

Tizanidine hydrochloride (what 1,518 Tizanidine Hydrochloride users reported?) has active ingredients of tizanidine hydrochloride. It is used in muscle spasms.

Methotrexate (what 131,102 Methotrexate users reported?) has active ingredients of methotrexate sodium. It is used in rheumatoid arthritis.

On Aug, 17, 2014: 306 people who take Tizanidine Hydrochloride, Methotrexate are studied

Tizanidine Hydrochloride, Methotrexate outcomes

Drug combinations in study:
- Tizanidine Hydrochloride (tizanidine hydrochloride)
- Methotrexate (methotrexate sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tizanidine Hydrochloride is effectiven/a0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
n/a0.00%
(0 of 5 people)
n/a100.00%
(1 of 1 people)
n/a
Methotrexate is effectiven/a0.00%
(0 of 3 people)
0.00%
(0 of 1 people)
n/a33.33%
(1 of 3 people)
n/a100.00%
(1 of 1 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
RhabdomyolysisJoint EffusionVulvovaginal PainInterstitial Lung DiseaseZygomycosisn/an/aFall
AbasiaUterine CancerHerpes ZosterHypoxiaBlood Culture PositivePyrexia
Blood Creatine Phosphokinase IncreasedCholelithiasisGenital HerpesUterine CancerArthralgia
HypersomniaDysuriaUrine Phosphate AbnormalJoint EffusionFatigue
FallImpaired Gastric EmptyingDysuriaPneumonia
AtelectasisLeukocytosisCholelithiasisPain
AnaemiaZygomycosisPainHypertension
HypertensionBlood Culture PositiveVocal Cord ParalysisNausea
CoughHaematomaCervix CarcinomaChest Pain
PneumoniaPneumoniaHeart Rate IncreasedBack Pain

Drug effectiveness by gender :

FemaleMale
Tizanidine Hydrochloride is effective0.00%
(0 of 4 people)
25.00%
(1 of 4 people)
Methotrexate is effective0.00%
(0 of 3 people)
40.00%
(2 of 5 people)

Most common drug interactions by gender * :

FemaleMale
FallPain Nos
PyrexiaPneumonia
ArthralgiaSplenomegaly
FatigueSepsis
PainMyalgia
HypertensionParaplegia
NauseaMultiple Sclerosis
PneumoniaInfluenza Like Illness
Back PainEmphysema
Chest PainRheumatoid Arthritis

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tizanidine Hydrochloride is effectiven/an/an/an/an/a0.00%
(0 of 5 people)
50.00%
(1 of 2 people)
0.00%
(0 of 1 people)
Methotrexate is effectiven/an/an/an/an/a0.00%
(0 of 6 people)
100.00%
(1 of 1 people)
100.00%
(1 of 1 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/aFaeces DiscolouredFibromyalgiaNauseaFallArthralgia
Weight DecreasedSubarachnoid HaemorrhageFatigueAnaemiaFall
HypokalaemiaPainIntervertebral DiscitisCoughAngiopathy
Biliary DyskinesiaHypertensionPainRhabdomyolysisPain Nos
CholesterosisSepsisArthralgiaPneumoniaHerpes Zoster
Cholecystitis ChronicSplenomegalyFallUrinary Tract InfectionHypochloraemia
Pain In ExtremityHeadacheHeadachePyrexiaMuscle Spasms
VomitingChest PainPain In ExtremityHypertensionMyalgia
Abdominal PainIncreased Tendency To BruisePyrexiaAbasiaOedema Peripheral
Abdominal Pain UpperInjection Site HaematomaMalaiseAtelectasisHypokalaemia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Tizanidine and Methotrexate
- group for people who take Methotrexate
- group for people who take Tizanidine Hydrochloride

Comments from related studies:

  • From this study (7 months ago):

  • I take methotexate weekly.. After a day of taking them, I have terrible chest pain that radiates to my neck, and down my sides

    Reply

Can you answer these questions (what is this?):

More questions for: Methotrexate, Tizanidine Hydrochloride

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  • Chills while on tizanidine
    Extremely sensitive to cold and have chills several times a day

More reviews for: Methotrexate, Tizanidine Hydrochloride

Complete drug side effects:

On eHealthMe, Tizanidine Hydrochloride (tizanidine hydrochloride) is often used to treat muscle spasms. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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