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Review: taking Tizanidine and Metoprolol Tartrate together

Summary: drug interactions are reported among people who take Tizanidine and Metoprolol Tartrate together.

This review analyzes the effectiveness and drug interactions between Tizanidine and Metoprolol Tartrate. It is created by eHealthMe based on reports of 321 people who take the same drugs from FDA and social media, and is updated regularly.


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On Mar, 5, 2015: 321 people who take Tizanidine Hydrochloride, Metoprolol Tartrate are studied

Tizanidine Hydrochloride, Metoprolol Tartrate outcomes

Drug combinations in study:
- Tizanidine Hydrochloride (tizanidine hydrochloride)
- Metoprolol Tartrate (metoprolol tartrate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tizanidine Hydrochloride is effective0.00%
(0 of 1 people)
(1 of 5 people)
(1 of 4 people)
(2 of 5 people)
(0 of 3 people)
(1 of 1 people)
(1 of 1 people)
Metoprolol Tartrate is effective50.00%
(1 of 2 people)
(0 of 1 people)
(1 of 2 people)
(3 of 8 people)
(5 of 6 people)
(1 of 1 people)

Drug effectiveness by gender :

Tizanidine Hydrochloride is effective33.33%
(6 of 18 people)
(0 of 2 people)
Metoprolol Tartrate is effective64.71%
(11 of 17 people)
(0 of 3 people)

Drug effectiveness by age :

Tizanidine Hydrochloride is effectiven/an/an/a100.00%
(1 of 1 people)
(1 of 3 people)
(3 of 39 people)
(0 of 3 people)
(1 of 1 people)
Metoprolol Tartrate is effectiven/an/an/a100.00%
(1 of 1 people)
(2 of 3 people)
(7 of 38 people)
(0 of 3 people)
(1 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Blood Pressure IncreasedIntermittent ClaudicationHallucinations, MixedSwelling Of The Ankles - Feet - LegsHypokalaemiaNumbness And TinglingHallucinations, MixedNausea
HypoventilationGraft InfectionHyaluronic Acid AbnormalSwelling In The AbdomenConvulsionAbdominal Pain AggravatedDyspnoea
PallorLung HyperinflationPetechiaeSwelling FaceCondition AggravatedMuscle TwitchingFatigue
Heart Rate IncreasedMassHyaluronic Acid AbnormalHypomagnesaemiaMuscle AchesAnxiety
DehydrationObstructive Airways DisorderSwelling Of A JointNeutropeniaFecal IncontinenceAsthenia
ComaGlaucomaWeight IncreasedPericardial EffusionBile Duct Pressure IncreasedChest Pain
Respiratory DepressionDyspnoeaConstipationNeutropenic SepsisTachycardia IrregularPain
Heart Rate DecreasedCoughSleep DisorderAnaemiaFatigueHeadache
Aspartate Aminotransferase IncreasedDepressionHallucinations, MixedFungal SepsisMigraineDepression
Hallucinations, MixedDysphagiaHeadache - Mixed Tension MigraineClostridium Difficile ColitisPain ExacerbatedOedema Peripheral

Most common drug interactions by gender * :

Chest PainCondition Aggravated
Drug IneffectiveChest Pain
DyspnoeaCardiac Failure Congestive

Most common drug interactions by age * :

n/an/an/aMetabolic AcidosisType 2 Diabetes MellitusNauseaPyrexiaRenal Failure
Confusional StateArthralgiaAnxietyDyspnoeaHypotension
Autonomic Nervous System ImbalanceDizzinessInsomniaFallFatigue
AmnesiaDiabetes MellitusFatigueMuscle SpasmsDyspnoea
Blood Chloride IncreasedHypertensionBalance DisorderCoughAsthenia
AnxietyWeight IncreasedHeadacheHeadacheDizziness
AphasiaPain In ExtremityPainUrinary Tract InfectionDepression
ScreamingParaesthesiaDyspnoeaChest PainTransient Ischaemic Attack
Mental Status ChangesAnaemiaFallNauseaCardiac Failure Congestive
Renal Tubular AcidosisTardive DyskinesiaHypertensionFatigueBack Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tizanidine and Metoprolol Tartrate?




You are not alone! Join a related support group:
- support group for people who take Metoprolol Tartrate
- support group for people who take Tizanidine Hydrochloride

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Tizanidine Hydrochloride (tizanidine hydrochloride) is often used to treat muscle spasms. Metoprolol Tartrate (metoprolol tartrate) is often used to treat high blood pressure. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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