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Review: Topamax and Ibuprofen

This review analyzes the effectiveness and drug interactions between Topamax and Ibuprofen. It is created by eHealthMe based on 979 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Mar, 31, 2014: 979 people who reported to have interactions when taking Topamax, Ibuprofen are studied

Trend of Topamax, Ibuprofen's drug interactions, side effects and effectiveness reports (4115732)

Drug combinations in study:
- Topamax (topiramate)
- Ibuprofen (ibuprofen)

eHealthMe real world results:

Most common interactions experienced by people in the use of Topamax, Ibuprofen:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Pain543
Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)495
Anxiety471
Headache (pain in head)383
Nausea (feeling of having an urge to vomit)380
Vomiting349
Dyspnoea (difficult or laboured respiration)294
Pulmonary Embolism (blockage of the main artery of the lung)284
Injury210
Cholecystitis Chronic (long lasting infection of gallbladder)208

Most common interactions experienced by people in long term use of Topamax, Ibuprofen:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety64
Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)64
Pain64
Emotional Distress64
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)57
Pulmonary Embolism (blockage of the main artery of the lung)52
Vomiting45
Cholecystitis Chronic (long lasting infection of gallbladder)32
Pneumonia28
Cholecystitis Acute (rapid infection of gallbladder)24

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Topamax0.00%11.11%55.56%22.22%11.11%
Ibuprofen0.00%40.00%60.00%0.00%0.00%

Top conditions involved for these people * :

  1. Migraine
  2. Pain
  3. Depression
  4. Foetal exposure during pregnancy
  5. Headache

Top co-used drugs for these people * :

  1. Seroquel
  2. Yaz
  3. Yasmin
  4. Motrin
  5. Ambien

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Ibuprofen, Topamax

You can also:

Complete drug side effects:

On eHealthMe, Topamax (topiramate) is often used to treat migraine. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (1 month ago):

  • Constant severe bouts of Cyclic Vomiting leave me confused, hostile, underweight, depressed and anxious. No meds seem to help... Exhausted and uncertain about the future.

    Reply

  • From this study (1 year ago):

  • Covered in rash over half my body after starting Topiramate. Have also tested positive for Lupus.

    Reply

    Patient Dar on Feb, 18, 2013:

    Complete list of symptoms that docs really don't want to hear at one time. Been going on for over 15 years. Headaches, low BP with high spikes that make me fall down, heart racing, hot flashes not related to menopause, cysts on top of each kidney, low white count and platelet count often, sores on head in nose and on face, so tired don't feel like doing anything, can't sleep without all the meds and then I only sleep a short time, positive anti-nuclear test. I feel like I am going crazy and now this rash is everywhere.

    Reply

    Ed on Mar, 5, 2013:

    Have your doctor check for Pheochromocytoma. I had all those symptoms and more. Pheo had grown around blood supply to kidney so it had to come out too. Much better since the surgery but I still have IBS, bipolar 2, low T, neuromuscular pain, one doctor wants to call it fibromyalgia

    Reply

    rmaran on Mar, 14, 2013:

    Have you had a sample taken of the sores to test them? One time I had a sore on my leg, they scraped a sample and performed a wide variety of tests on it. F 34 CA

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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