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Review: taking Topamax and Ibuprofen together

Summary: drug interactions are reported among people who take Topamax and Ibuprofen together.

This review analyzes the effectiveness and drug interactions between Topamax and Ibuprofen. It is created by eHealthMe based on reports of 1,025 people who take the same drugs from FDA and social media, and is updated regularly.


You are not alone: join a support group for people who take Topamax and Ibuprofen >>>

On Mar, 28, 2015: 1,025 people who take Topamax, Ibuprofen are studied

Topamax, Ibuprofen outcomes

Drug combinations in study:
- Topamax (topiramate)
- Ibuprofen (ibuprofen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Topamax is effective50.00%
(1 of 2 people)
(7 of 15 people)
(0 of 2 people)
(1 of 7 people)
(0 of 4 people)
(7 of 7 people)
(2 of 4 people)
(1 of 3 people)
Ibuprofen is effective40.00%
(2 of 5 people)
(1 of 2 people)
(0 of 6 people)
(0 of 4 people)
(0 of 2 people)
(2 of 5 people)
(0 of 12 people)
(3 of 5 people)

Drug effectiveness by gender :

Topamax is effective44.19%
(19 of 43 people)
(0 of 1 people)
Ibuprofen is effective20.00%
(8 of 40 people)
(0 of 1 people)

Drug effectiveness by age :

Topamax is effectiven/an/a50.00%
(1 of 2 people)
(5 of 20 people)
(4 of 24 people)
(8 of 42 people)
(1 of 16 people)
(0 of 3 people)
Ibuprofen is effectiven/an/a0.00%
(0 of 2 people)
(1 of 20 people)
(2 of 23 people)
(3 of 41 people)
(1 of 14 people)
(1 of 3 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
FallFallBone Marrow DepressionDeep Vein ThrombosisPainAnxietyPulmonary EmbolismPain
Suicide AttemptAnxietyDiabetes MellitusPulmonary EmbolismEmotional DistressPainDeep Vein ThrombosisNausea
LethargyPainDysaesthesiaOedema PeripheralAnxietyPneumoniaConstipation AggravatedHeadache
Communication DisorderPulmonary EmbolismObesityNauseaCholecystitis ChronicPulmonary EmbolismBipolar DisorderDeep Vein Thrombosis
IncoherentWeight IncreasedTardive DyskinesiaCholelithiasisVomitingEmotional DistressMigraineAnxiety
TremorGastrooesophageal Reflux DiseaseNeuropathy PeripheralAbdominal PainDeep Vein ThrombosisCholelithiasisDepressionVomiting
Bipolar DisorderLimb InjuryNauseaSwellingGallbladder DisorderLeukocytosisAllergiesPulmonary Embolism
DeliriumImpaired Driving AbilityHeadachePainAnhedoniaTachycardiaEndometriosisDizziness
PainLoss Of ConsciousnessGlucose Tolerance ImpairedWeaknessCholelithiasisCholecystitis AcuteDry MouthFatigue
Eye Movement DisorderPost-traumatic Stress DisorderMovement DisorderRestlessnessAbdominal Pain UpperGeneral Physical Health DeteriorationBone And Joint PainDepression

Most common drug interactions by gender * :

Deep Vein ThrombosisCough
Pulmonary EmbolismFall
DepressionNeck Pain
VomitingBack Pain

Most common drug interactions by age * :

n/aPancreatitis NosDeep Vein ThrombosisPainPainPainNauseaVision Blurred
Vomiting NosHeadacheCholecystitis ChronicHeadacheNauseaHeadachePain
Inappropriate Antidiuretic Hormone SecretionGallbladder DisorderGallbladder DisorderNauseaHeadacheHypoaesthesiaHeadache
HaematemesisPsychotic DisorderDeep Vein ThrombosisPulmonary EmbolismDeep Vein ThrombosisDizzinessNausea
Drug IneffectiveConvulsionInjuryCholelithiasisAnxietyFallLoss Of Consciousness
Urinary Tract Infection NosCholecystitis ChronicAnxietySuicidal IdeationDiabetes MellitusNeck PainAnxiety
PneumoniaDizzinessPulmonary EmbolismDepressionFatigueFatigueVertigo
PyrexiaMigraineAbdominal PainDeep Vein ThrombosisPulmonary EmbolismPainScar
ConvulsionPulmonary EmbolismNauseaCholecystitis ChronicVomitingMalaiseToothache
Depressed Level Of ConsciousnessPainVomitingAnxietyOedema PeripheralDiarrhoeaEmotional Distress

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Do you take Topamax and Ibuprofen?




You are not alone! Join a related support group:
- support group for people who take Ibuprofen
- support group for people who take Topamax

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Topamax (topiramate) is often used to treat migraine. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

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