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Review: Topamax and Ibuprofen





Summary: drug interactions are reported among people who take Topamax and Ibuprofen together.

This review analyzes the effectiveness and drug interactions between Topamax and Ibuprofen. It is created by eHealthMe based on reports of 1,023 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Topamax and Ibuprofen >>>

What are the drugs

Topamax has active ingredients of topiramate. It is often used in migraine. (latest outcomes from Topamax 24,579 users)

Ibuprofen has active ingredients of ibuprofen. It is often used in pain. (latest outcomes from Ibuprofen 61,602 users)

On Nov, 26, 2014: 1,023 people who take Topamax, Ibuprofen are studied

Topamax, Ibuprofen outcomes

Drug combinations in study:
- Topamax (topiramate)
- Ibuprofen (ibuprofen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Topamax is effective50.00%
(1 of 2 people)
50.00%
(7 of 14 people)
0.00%
(0 of 2 people)
14.29%
(1 of 7 people)
0.00%
(0 of 3 people)
100.00%
(7 of 7 people)
50.00%
(2 of 4 people)
33.33%
(1 of 3 people)
Ibuprofen is effective40.00%
(2 of 5 people)
50.00%
(1 of 2 people)
0.00%
(0 of 6 people)
0.00%
(0 of 3 people)
0.00%
(0 of 1 people)
40.00%
(2 of 5 people)
0.00%
(0 of 12 people)
60.00%
(3 of 5 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
FallAnxietyBone Marrow DepressionDeep Vein ThrombosisPainAnxietyPulmonary EmbolismPain
Suicide AttemptPainDiabetes MellitusPulmonary EmbolismAnxietyPainDeep Vein ThrombosisNausea
LethargyFallDysaesthesiaOedema PeripheralEmotional DistressPneumoniaConstipation AggravatedHeadache
Communication DisorderWeight IncreasedObesityNauseaCholecystitis ChronicPulmonary EmbolismBipolar DisorderDeep Vein Thrombosis
IncoherentGastrooesophageal Reflux DiseaseTardive DyskinesiaAbdominal PainDeep Vein ThrombosisEmotional DistressMigraineAnxiety
TremorPulmonary EmbolismNeuropathy PeripheralCholelithiasisVomitingCholelithiasisDepressionVomiting
Bipolar DisorderEating DisorderNauseaSwellingGallbladder DisorderLeukocytosisAllergiesPulmonary Embolism
DeliriumDepressionHeadachePainAnhedoniaTachycardiaEndometriosisDizziness
PainDrug AbuseGlucose Tolerance ImpairedVomitingCholelithiasisCholecystitis AcuteDry MouthFatigue
Eye Movement DisorderConfusional StateMovement DisorderTricuspid Valve IncompetenceNauseaGeneral Physical Health DeteriorationBone And Joint PainDepression

Drug effectiveness by gender :

FemaleMale
Topamax is effective46.34%
(19 of 41 people)
0.00%
(0 of 1 people)
Ibuprofen is effective21.05%
(8 of 38 people)
0.00%
(0 of 1 people)

Most common drug interactions by gender * :

FemaleMale
PainHypoaesthesia
NauseaSinusitis
HeadacheHeadache
AnxietyPneumonia
Deep Vein ThrombosisCough
Pulmonary EmbolismFall
DepressionNeck Pain
VomitingBack Pain
InjuryConjunctivitis
FatiguePain

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Topamax is effectiven/an/a50.00%
(1 of 2 people)
25.00%
(5 of 20 people)
16.67%
(4 of 24 people)
27.59%
(8 of 29 people)
7.14%
(1 of 14 people)
0.00%
(0 of 3 people)
Ibuprofen is effectiven/an/a0.00%
(0 of 2 people)
5.00%
(1 of 20 people)
8.70%
(2 of 23 people)
10.71%
(3 of 28 people)
8.33%
(1 of 12 people)
33.33%
(1 of 3 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aPancreatitis NosDeep Vein ThrombosisPainPainPainNauseaVision Blurred
Vomiting NosHeadacheCholecystitis ChronicHeadacheNauseaHeadachePain
Inappropriate Antidiuretic Hormone SecretionGallbladder DisorderGallbladder DisorderNauseaHeadacheHypoaesthesiaHeadache
HaematemesisPsychotic DisorderDeep Vein ThrombosisPulmonary EmbolismDeep Vein ThrombosisDizzinessNausea
Drug IneffectiveConvulsionInjuryCholelithiasisAnxietyFallLoss Of Consciousness
Urinary Tract Infection NosCholecystitis ChronicAnxietySuicidal IdeationDiabetes MellitusNeck PainAnxiety
PneumoniaDizzinessPulmonary EmbolismDepressionPulmonary EmbolismFatigueVertigo
PyrexiaMigraineAbdominal PainDeep Vein ThrombosisFatiguePainScar
ConvulsionPulmonary EmbolismNauseaCholecystitis ChronicOedema PeripheralDiarrhoeaToothache
Depressed Level Of ConsciousnessPainVomitingAnxietyVomitingFeeling AbnormalEmotional Distress

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Topamax and Ibuprofen?

You are not alone! Join a related mobile support group:
- support group for people who take Topamax and Ibuprofen
- support group for people who take Ibuprofen
- support group for people who take Topamax

Can you answer these questions (Ask a question):

  • Is it safe to take demerol while taking tramadol hydrochloride and hydroxychloroquine (2 answers)
    I am experiencing acute, debilitating pain due to the Chikungunya virus, which has reintroduced all of the previous painful symptoms I have,ongoing and in the past, from Fibromyalgia, Arthritis, tendonitis and severe headaches. It's in its 38th day and I am basically crippled from neck to feet. Have to sleep propped up as arms throb with pain when horizontal. The only thing that has subdued the pain slightly are Oxycocet and Ibuprofen, but the pain never goes away. My hands and feet are so inflammed it's difficult to perform even the smallest tasks of personal hygiene and housekeeping. I have difficulty controlling my bladder and often don't make it to the washroom in time. Just started on Demerol today so will no longer take the Oxycocet, but am concerned of the interactions with Demerol, Hydroxychloroquine and Tramadol Hydrochloride extended release tablets that I take daily for the Fibromyalgia and Arthritis. I have dealt with a great deal of pain through the years, but I now have the pain of every serious illness I have had in my lifetime, all at the same time. I honestly didn't think a person could deal with this much pain at once. I have tried and am still taking several vitamins and herbal supplements as well as drinking tons of water and eating really well. Lots of berries, dark vegetables, apples, yogurt and minimal meat. Taking turmeric, papaya leaf, ginger, cinnamon and boswellia for the inflammation. Taking minimal wheat products, sugar and no alcohol. Also, drinking green, fennel and nettle tea daily. I know this is a lot of information, but I really need help and wonder if anyone has any suggestions! Thanking you in advance!!!
  • Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
    I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
  • Is ibuprofen safe to use if i have retinitis pigmentosa?
    I have bulging disc pain that I use Ibuprofen for. I can be pain free for weeks/months and take nothing. When I have a flair up I can take up to 8x200mg per day. I have heard this may affect my RP. Can you advise?
  • Can mrsa cause chronic intestinal pseudo obstruction?
    I had a small bowel obstruction caused by adhesions from an appendectomy carried out 20yrs previously and had grumbling pain ever since but been labelled a malingerer by my family GP until one day at work when I started with terrible tummy ache and sickness like I'd never known, fetching up bile with force. I hated going to hospital after yrs of being called a moaner but after a day of rolling round in pain, temperature of 103 an dehydration, my Mammy insisted we go and I was seen straight away - to my shock I was in theatre within 3hrs with a serious obstruction.
    I never really recovered... The obstruction returned after 2 days and a portion of necrotic bowel was removed, then further fever and cellulitis then MRSA and deaths door.... Isolation in high dependency (intensive care) wound break down, ventilated and all related issues that come with that - chest infection, pneumonia, bed sores. Total time in hospital 8 months. Negative pressure dressing on laparotomy wound, colostomy, picc, 4 rounds of vancomycin, minor flirt with heart failure (just water related) an eventually everything healed. Had a large incisional hernia to repair and some corrective work to the horrific scarring but then the neuropathy started plus problems eating, spewing up after any solid food, more than a few forks, diarrhoea and sickness or constipation nausea and pain driving me mad, tried all manner of drugs, nerve blocks, physio, floating tank, acupuncture, opiates, non opiates, spinal cord stimulation, an now a consultant just had a 'eureka' moment and said were you treated with vancomycin when you had MRSA? If so I'm pretty sure you have chronic intestinal pseudo obstruction and is 90% sure but wants to take a muscle biopsy to be certain. I've had so much surgery and bad news in the last 10yrs I'm terrified of germs, hospital acquired bugs and anaesthetics, is there any other way? Or can I have this test done awake - conscious sedation? I had it before during spinal cord surgery so I know what's involved and it's better than GA as I know what's going on, who is doing what to me etc...
    Does anyone with a medical background know about this ailment/disease? Does it sound feasible that MRSA or it's treatment could have caused this? I was surgically debrided up to every other day when the vac pac/negative pressure machine and dressings were changed and the doctors told me I lost a great deal of tissue and had a lot of nerve damage due to the infection.
    Any patient perspectives on this illness would also be very much valued in helping me make a decision, moving forward. If all this is going to accomplish is to attach a label to the pain but not actually change anything, after fighting it for 10yrs now, avoiding hospital as much as I can, I really can't see the point of exploratory surgerys and biopsys now when it is known that I have this propensity towards adhesions and a new wound means a potentially new adhesion growth site.
    If it helps, the appendectomy happened when I was 10yrs old, the MRSA when I was 30 and I am now 40.
    Beat Wishes.
  • Is it safe to take effexor and ibuprophen?
    Have sinus infection which I'm taking doxycycline and ibuprophen for headache. I also take Venlafaxine for GAD. Is it okay to take Advil or acetaminophen while taking venlafaxine, not at the same time??

More questions for: Ibuprofen, Topamax

You may be interested at these reviews (Write a review):

  • Urea urine increased while taking topamax
    I was on Topamax to lose weight. It worked for me, I lost weight but my blood urea increased. I have to stop taking it.
  • Massive aggression within first 4 days at 50mg (1 response)
    am only taking 50mg and have only been taking it for 4 days(this is the evening of the 4th day)as a preventative for migraine headaches that I have suffered from from 16 years. I have had pins and needles in my hands and feet as well as spontaneous crying fits since day 2 and Major aggression since yesterday. With normally an insurmountable amount of patience with my 1 year old son, I outright yelled at him last night. This is unacceptable. I have never felt such quick and sudden rage over nothing before, well, over anything before.
  • Wheezing stopped after topamax sessesion
    Wheezing noted by primary physician in this non-smoker. Stopped Topamax per doctor's instruction. 48 hours later was examined by physician and noted that wheezing stopped.
  • Seizure disorder med problems (1 response)
    Velafaxine 150 mg. 1 per day.

    In process of switching from Topiramate 50 mg. 1 pill in morning & one at night (going off of this because of kidney stones) Was on this medication approximately 10 years.

    Lamotrigine 2 25mg pills in morning and 2 - 25 mg. pills at night.

    On the 3rd day of the 2nd week of switching I started the nightmares. I took a one hour nap and had a nightmare that seemed like it went on the entire time. Even if I slept for 20 minutes I had a dream or nightmare. I've sometimes been known to have vivid dreams but never this constant in my entire life. Also, very seldom do I have such terrible dreams. So many in one evening. They are an occasional thing, not an all night long thing.

    Also, I have sinus trouble occasionally. The same day the nightmares began I got a terrible headache behind my one eye and under my eye. I have no drainage yet anyway. Not sure if this is during the start up of this medicine, but if I had known it could cause trouble with sinus I would never have started it.

    I was put on this as a quick back up plan when the medicine we agreed upon - Levetireacetam made me feel drunk feeling and I had to be careful just walking around my homes and steps.
  • Psychosis, weight loss and topamax (1 response)
    I had a brain hemorrhage in my occipital lobe. It left me with with a partial seizure disorder. The seizures would interrupt my ability to see. I was trying different anti-seizure medication and they all made me more tired and more depressed. My neurologist decided to try topamax. On topamax I began to feel more energetic and started losing weight. For the first time in years I woke up in the morning feeling zippy. I started feeling euphoric sometimes. I started to feel like I was glowing with life. I became so energetic I was like someone in a manic state. My temper got shorter and I began to hallucinate. I started to see angels and/or feel their presence. I live in a big city and there are a lot of people who are pretty mean here and I decided I wasn't going to let any of them push me around. I wasn't diplomatic anymore with anyone. Basically everyone thought I had gone crazy and I guess I had.
    My psychiatrist saw me and told my neurologist to "Get Her Off The Topamax!" After I stopped taking it and was more my normal tired self, my psychiatrist told me that I had been psychotic and that I had scared him. Unfortunately, after I stopped taking topamax I gained back the 30 pounds I had lost and none of my new clothes fit me. My doctors told me that they had never seen Topamax affect anyone the way it had affected me. They said it usually makes people more sedated. Hopefully, sharing my experience with Topamax will be helpful to someone.

More reviews for: Ibuprofen, Topamax

Comments from related studies:

  • From this study (3 weeks ago):

  • I have OCD but after I started Zonegram 50mg bd 3 days ago, I have noticed my anxiety getting increasingly worse and I had a severe panic attack yesterday. The Zonegram has also decreased the severe paranoia I feel with the ketamine but it has introduced some memory loss. Otherwise I feel the best I have in years. Should I swap my antidepressant to help with the anxiety?

    I recently came off Gabapentin (1800 tds --> 1200bd --> tapering down to nothing) and noticed my baseline pain level rising, hence the starting of the Zonegran.

    How can I be sure the the positive side effects of the Zonegran are not going to disappear once I leave hospital and stop the ketamine and morphine? Basically is what I'm feeling just a reaction of the Zonegran and ketamine or will the Zonegran continue to work in my favour (minus the anxiety and memory loss) once I leave hospital?

    I am in hospital now, I have entered hospital for Multiple Sclerosis neuropathic pain and am on these drugs to treat neuropathic pain but suspect I may also have Crohn's Disease/ulcerative colitis/irritable bowel syndrome hence the Neuropathic Pain and Abdominal Pain.

    Reply

  • From this study (3 months ago):

  • Constant severe bouts of Cyclic Vomiting leave me confused, hostile, underweight, depressed and anxious. No meds seem to help... Exhausted and uncertain about the future.

    Reply

    Harmony2 on Sep, 26, 2014:

    My daughter experience the same set of symptoms every time she has an attack. We have found some things that would help, many things to avoid, and some things that are triggers. Contact us with any questions you have and we will do our best to help you.

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Topamax (topiramate) is often used to treat migraine. Ibuprofen (ibuprofen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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