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Review: taking Toprol-xl and Vitamin B12 together

Summary: drug interactions are reported among people who take Toprol-xl and Vitamin B12 together.

This review analyzes the effectiveness and drug interactions between Toprol-xl and Vitamin B12. It is created by eHealthMe based on reports of 64 people who take the same drugs from FDA and social media, and is updated regularly.


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On Apr, 5, 2015: 64 people who take Toprol-xl, Vitamin B12 are studied

Toprol-xl, Vitamin B12 outcomes

Drug combinations in study:
- Toprol-xl (metoprolol succinate)
- Vitamin B12 (cobalamin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Toprol-xl is effective0.00%
(0 of 1 people)
(1 of 2 people)
(3 of 3 people)
(3 of 6 people)
(1 of 2 people)
(0 of 1 people)
Vitamin B12 is effective0.00%
(0 of 1 people)
(2 of 2 people)
(2 of 3 people)
(0 of 1 people)
(3 of 3 people)
(3 of 4 people)

Drug effectiveness by gender :

Toprol-xl is effective62.50%
(5 of 8 people)
(3 of 7 people)
Vitamin B12 is effective57.14%
(4 of 7 people)
(6 of 7 people)

Drug effectiveness by age :

Toprol-xl is effectiven/an/an/an/an/a66.67%
(2 of 3 people)
(4 of 13 people)
(2 of 10 people)
Vitamin B12 is effectiven/an/an/an/an/a100.00%
(2 of 2 people)
(6 of 15 people)
(2 of 7 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
ConfusionPo2 IncreasedNerve CompressionLewy Body DementiaDrug HypersensitivityMood SwingsPo2 IncreasedBlood Pressure Increased
Frequent Or Urgent UrinationErectile DysfunctionDiarrhoea AggravatedRash NosInsomniaDrug HypersensitivityCardiac Failure Congestive
High Blood PressureMood SwingsHigh Blood PressureFrequent Or Urgent UrinationHaemorrhoids
InsomniaErectile DysfunctionAtrial FibrillationNausea
AnxietyNerve CompressionHigh Blood Cholesterol And TriglyceridesHypersensitivity
ConfusionConfusionHigh Blood PressureAsthma
Short-term Memory LossAnxietyBipolar 1Insomnia Nec
Diarrhoea AggravatedInappropriate Antidiuretic Hormone Secretion
Lewy Body DementiaRenal Failure
Short-term Memory LossDysarthria

Most common drug interactions by gender * :

Blood Pressure IncreasedAngina Unstable
Inappropriate Antidiuretic Hormone SecretionHigh Blood Pressure
Cardiac Failure CongestivePharyngeal Oedema
NauseaDry Skin
HypoaesthesiaDeafness Nos
Insomnia NecEczema Nos
Renal FailureRash Pruritic
DysarthriaUrinary Frequency

Most common drug interactions by age * :

n/an/an/an/an/aGestational DiabetesHaemorrhoidsNausea
Emotional DisorderHypoaesthesiaHypersensitivity
Drug IneffectiveDysarthriaCardiac Failure Congestive
HaemorrhoidsInappropriate Antidiuretic Hormone SecretionPharyngeal Oedema
InjuryMemory ImpairmentVomiting
Rectal HaemorrhageTendonitisRash Generalised
Pregnancy Induced HypertensionFibromyalgiaTachycardia
PregnancyBursitisFace Oedema
Intra-uterine DeathType Ii HyperlipidaemiaOedema Peripheral
Drug Exposure During PregnancyVomiting ProjectileDiarrhoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Toprol-xl
- support group for people who take Vitamin B12

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Toprol-xl (metoprolol succinate) is often used to treat high blood pressure. Vitamin B12 (cobalamin) is often used to treat vitamin b12 deficiency. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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