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Review: Amitriptyline and Tramadol

This review analyzes the effectiveness and drug interactions between Amitriptyline and Tramadol. It is created by eHealthMe based on 2,838 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 5, 2014: 2,838 people who reported to have interactions when taking Amitriptyline Hydrochloride, Tramadol are studied

Trend of Amitriptyline Hydrochloride, Tramadol's drug interactions, side effects and effectiveness reports (4090961)

Drug combinations in study:
- Amitriptyline Hydrochloride (amitriptyline hydrochloride)
- Tramadol (tramadol hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Amitriptyline Hydrochloride, Tramadol:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety1,318
Dyspnoea (difficult or laboured respiration)1,060
Pain981
Asthenia (weakness)977
Arthralgia (joint pain)933
Vomiting930
Headache (pain in head)796
Nausea (feeling of having an urge to vomit)766
Fatigue (feeling of tiredness)725
Depression723

Most common interactions experienced by people in long term use of Amitriptyline Hydrochloride, Tramadol:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety95
Nightmare (unpleasant dream)95
Depression95
Suicidal Ideation95
Fatigue (feeling of tiredness)90
Dizziness90
Drug Interaction88
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)88
Malaise (a feeling of general discomfort or uneasiness)86
Headache (pain in head)86

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Amitriptyline Hydrochloride0.00%40.91%45.45%9.09%4.55%
Tramadol10.53%26.32%52.63%5.26%5.26%

Top conditions involved for these people * :

  1. Pain
  2. Rheumatoid arthritis
  3. Depression
  4. Hypertension
  5. Back pain

Top co-used drugs for these people * :

  1. Amitriptyline hcl
  2. Ultram
  3. Elavil
  4. Neurontin
  5. Aspirin

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Amitriptyline Hydrochloride, Tramadol

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Complete drug side effects:

On eHealthMe, Amitriptyline Hydrochloride (amitriptyline hydrochloride) is often used to treat migraine. Tramadol (tramadol hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (1 month ago):

  • taking 1 50mg tablet amitriptyline daily
    taking 8 50mg tablets tramadol daily
    taking 2 500mg tablets naproxen daily

    Reply

  • From this study (3 months ago):

  • Meds are not ridding me of headaches or migraines, & now I have insomnia & acne! :( No longer on Verapamil or Simvistatin, just over one yr now. Off of Amitriptalyne since August, off of Celexa since Sept/October... allergies & insomnia crept up during transition from Amitriptaline/Celexa to Cymbalta.

    Reply

  • From this study (6 months ago):

  • Have been reluctant to leave house,
    The symptoms started when I began to take the meds..Symptoms started December 2012, and are still with me now in Oct 2013
    I have had bowel investigations ..all clear

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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