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Review: Tramadol and Melatonin

This review analyzes the effectiveness and drug interactions between Tramadol and Melatonin. It is created by eHealthMe based on reports of 166 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: get help anytime and anywhere for people who take Tramadol and Melatonin >>>

What are the drugs

Tramadol (latest outcomes from 41,369 users) has active ingredients of tramadol hydrochloride. It is often used in pain.

Melatonin (latest outcomes from 2,611 users) has active ingredients of melatonin. It is often used in insomnia.

On Jul, 16, 2014: 166 people who take Tramadol, Melatonin are studied

Tramadol, Melatonin outcomes

Drug combinations in study:
- Tramadol (tramadol hydrochloride)
- Melatonin (melatonin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol is effective0.00%
(0 of 4 people)
0.00%
(0 of 2 people)
0.00%
(0 of 2 people)
25.00%
(1 of 4 people)
40.00%
(2 of 5 people)
50.00%
(1 of 2 people)
0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
Melatonin is effective0.00%
(0 of 3 people)
33.33%
(2 of 6 people)
50.00%
(3 of 6 people)
0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
RestlessnessShort-term Memory LossExercise Tolerance DecreasedInsomniaWeight Gain - UnintentionalSkin HyperpigmentationPruritus AggravatedAnxiety
Panic AttacksLong-term Memory LossSkin HyperpigmentationRestlessnessHeadacheDecreased InterestNight SweatsDepression
Visual ImpairmentBlood Cortisol AbnormalDecreased InterestInability To CrawlHeartburn - ChronicBone PainDizziness AggravatedInsomnia
Visual BrightnessBlood Cortisol IncreasedHeat IntoleranceFear Of Public SpeakingPalpitationsExercise Tolerance DecreasedRestless Leg SyndromeBack Pain
Generalized Anxiety DisorderBlood Cortisol DecreasedIncreased Tendency To BruiseFatigueInsomniaHeat IntoleranceWeight Above NormalArthralgia
Major Depressive DisorderRestlessnessLung NoduleThrombocytopeniaRestlessnessFallImpaired Healing
TachycardiaThrombocytopeniaMuscle TwitchingMuscle TwitchingIncreased Tendency To BruiseGait Disturbance
HypomaniaFallMood SwingsItchingDecreased ActivityMuscular Weakness
Gender Identity DisorderBone PainDepressionMalaiseAppetite IncreasedCough
Breathing - Slowed Or StoppedDecreased ActivityPanic AttacksDrowsinessMigraine AggravatedNausea

Drug effectiveness by gender :

FemaleMale
Tramadol is effective21.05%
(4 of 19 people)
50.00%
(1 of 2 people)
Melatonin is effective35.29%
(6 of 17 people)
50.00%
(1 of 2 people)

Most common drug interactions by gender * :

FemaleMale
InsomniaAnxiety
DepressionSpinal Column Stenosis
AnxietyAsthenia
Back PainDyspnoea
Impaired HealingDysphemia
TremorOsteolysis
Gait DisturbanceMetastases To Bone
Muscular WeaknessThyroid Cancer
CoughChills
ArthralgiaGastrooesophageal Reflux Disease

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tramadol is effectiven/an/a0.00%
(0 of 1 people)
2.99%
(2 of 67 people)
3.92%
(2 of 51 people)
0.00%
(0 of 7 people)
14.29%
(1 of 7 people)
0.00%
(0 of 3 people)
Melatonin is effectiven/an/a0.00%
(0 of 1 people)
2.94%
(1 of 34 people)
8.16%
(4 of 49 people)
0.00%
(0 of 7 people)
14.29%
(1 of 7 people)
33.33%
(1 of 3 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aEpistaxisMuscle SpasmsInsomniaPainGastrooesophageal Reflux DiseaseArthralgia
Anal HaemorrhageNauseaPainFatigueMetastases To BoneNausea
ScabPallorArthralgiaBalance DisorderMental Status ChangesAbdominal Pain Upper
Nasal CongestionChillsDepressionWeight IncreasedBack PainVomiting
Intentional Self-injuryDizzinessTremorOedema PeripheralCoughFatigue
Weight IncreasedSinusitisHeart Rate IncreasedNauseaGait DisturbanceFall
Rash PapularSepsisBlood Creatinine IncreasedHeadacheMuscular WeaknessDepression
Rash PruriticAstheniaAccident At WorkParaesthesiaToothacheAsthenia
CushingoidPollakiuriaCervicobrachial SyndromeDrug IneffectiveImpaired HealingMuscle Spasms
OverweightSomnolenceAngerNephrogenic Systemic FibrosisInjuryAnxiety

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Tramadol and Melatonin
- group for people who take Melatonin
- group for people who take Tramadol

Comments from related studies:

  • From this study (4 months ago):

  • suspicious lung nodule seen in x-ray, going in for a cat scan

    Reply

  • From this study (1 year ago):

  • Covered in rash over half my body after starting Topiramate. Have also tested positive for Lupus.

    Reply

    Patient Dar on Feb, 18, 2013:

    Complete list of symptoms that docs really don't want to hear at one time. Been going on for over 15 years. Headaches, low BP with high spikes that make me fall down, heart racing, hot flashes not related to menopause, cysts on top of each kidney, low white count and platelet count often, sores on head in nose and on face, so tired don't feel like doing anything, can't sleep without all the meds and then I only sleep a short time, positive anti-nuclear test. I feel like I am going crazy and now this rash is everywhere.

    Reply

    Ed on Mar, 5, 2013:

    Have your doctor check for Pheochromocytoma. I had all those symptoms and more. Pheo had grown around blood supply to kidney so it had to come out too. Much better since the surgery but I still have IBS, bipolar 2, low T, neuromuscular pain, one doctor wants to call it fibromyalgia

    Reply

    rmaran on Mar, 14, 2013:

    Have you had a sample taken of the sores to test them? One time I had a sore on my leg, they scraped a sample and performed a wide variety of tests on it. F 34 CA

    Reply

Post a new comment    OR    Read more comments

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Complete drug side effects:

On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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