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Review: Tramadol and Metformin

This review analyzes the effectiveness and drug interactions between Tramadol and Metformin. It is created by eHealthMe based on reports of 2,645 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: get help anytime and anywhere for people who take Tramadol and Metformin >>>

What are the drugs

Tramadol (latest outcomes from 41,369 users) has active ingredients of tramadol hydrochloride. It is often used in pain.

Metformin (latest outcomes from 100,693 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.

On Jul, 12, 2014: 2,645 people who take Tramadol, Metformin are studied

Tramadol, Metformin outcomes

Drug combinations in study:
- Tramadol (tramadol hydrochloride)
- Metformin (metformin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol is effective25.00%
(1 of 4 people)
60.00%
(3 of 5 people)
55.56%
(5 of 9 people)
0.00%
(0 of 5 people)
33.33%
(4 of 12 people)
33.33%
(3 of 9 people)
66.67%
(2 of 3 people)
n/a
Metformin is effective0.00%
(0 of 1 people)
42.86%
(3 of 7 people)
16.67%
(1 of 6 people)
42.86%
(3 of 7 people)
44.44%
(4 of 9 people)
60.00%
(6 of 10 people)
42.86%
(3 of 7 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Pulmonary EmbolismObsessive-compulsive Personality DisorderMalaiseRenal Failure AcuteAnxietyDiarrhoeaFatiguePain
SomnolencePathological GamblingVomitingPeripheral Vascular DisorderRenal Failure AcuteBack PainElectrocardiogram Pr ProlongationFatigue
Confusional StateHypersexualityNauseaMyocardial InfarctionAggressionCerebrovascular AccidentHyperkalaemiaNausea
Thrombotic Thrombocytopenic PurpuraEmotional DistressPyrexiaAmnesiaCerebrovascular AccidentHepatic SteatosisMetabolic AcidosisDyspnoea
Renal Failure AcuteSkin ExfoliationPancreatitis ChronicIliac Artery StenosisDepressionHyperkalaemiaUrinary Tract InfectionVomiting
KetosisDepressionHepatic SteatosisThrombosisMental DisorderDyspepsiaHyponatraemiaAnaemia
FallSuicidal IdeationHyperkalaemiaConfusional StateCystConstipationNauseaDiabetes Mellitus
Deep Vein ThrombosisPulmonary EmbolismBack PainMydriasisCardiovascular DisorderWeight DecreasedRunny NoseChest Pain
NauseaRestlessnessWeight DecreasedDehydrationLiver Function Test AbnormalMalaiseVomitingDiarrhoea
Diabetes MellitusHypoglycaemiaSciaticaMental DisorderLiver DisorderMetabolic AcidosisSleepiness - During The DayAsthenia

Drug effectiveness by gender :

FemaleMale
Tramadol is effective32.26%
(10 of 31 people)
50.00%
(8 of 16 people)
Metformin is effective30.00%
(9 of 30 people)
64.71%
(11 of 17 people)

Most common drug interactions by gender * :

FemaleMale
PainNausea
FatigueFatigue
NauseaAsthenia
AnaemiaVomiting
DyspnoeaDyspnoea
VomitingMyocardial Infarction
Diabetes MellitusDiarrhoea
Chest PainDepression
Pleural EffusionDiabetes Mellitus
HaemorrhoidsPain

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tramadol is effectiven/an/an/a100.00%
(1 of 1 people)
20.00%
(2 of 10 people)
25.00%
(3 of 12 people)
31.82%
(7 of 22 people)
20.83%
(5 of 24 people)
Metformin is effectiven/an/an/a0.00%
(0 of 1 people)
11.11%
(1 of 9 people)
38.46%
(5 of 13 people)
34.78%
(8 of 23 people)
26.09%
(6 of 23 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
TremorInfluenza Like IllnessBiliary DyskinesiaDyspnoeaDiabetes MellitusDiabetes MellitusNauseaFatigue
Muscular WeaknessJoint SwellingCholecystitis ChronicNauseaType 2 Diabetes MellitusNauseaDepressionAnaemia
Type 2 Diabetes MellitusMyositisGallbladder DisorderDiabetes MellitusDeep Vein ThrombosisPainAnxietyPain
Neoplasm MalignantArthritis BacterialOropharyngeal PainCholelithiasisPainType 2 Diabetes MellitusPainHaemorrhoids
ObesityLethargyHypoglycaemiaCholecystitis ChronicPulmonary EmbolismVomitingMyocardial InfarctionColonic Polyp
LeiomyomaMultiple Drug Overdose AccidentalHypertensionChest PainDiabetic NeuropathyHeadacheDiarrhoeaPleural Effusion
Cerebrovascular AccidentSomnolenceCoughPulmonary EmbolismDehydrationBack PainVomitingGastritis Erosive
OsteoarthritisAccidental Drug Intake By ChildDiabetes MellitusVomitingKetosisChest PainDizzinessCystitis
Patellofemoral Pain SyndromeDyshidrosisBack PainHeadacheDiarrhoeaChest PainHepatic Enzyme Increased
HyperprolactinaemiaBack PainNeck PainNeuropathy PeripheralDyspnoeaArthralgiaMuscle Twitching

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Tramadol and Metformin
- group for people who take Metformin
- group for people who take Tramadol

Comments from related studies:

  • From this study (5 months ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness. WBCs run 10.5 to 13.0 consistently. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increased & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

  • From this study (5 months ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness.WBCs run 10.5 tp 13.0 consistanly. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increase & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

  • From this study (6 months ago):

  • had sciatica and an epidural shot. After the shot tremors started on left leg and now I have been diagnosed with early Parkinsons. Can the tremors be caused by a drug interaction? The tremors stopped after taking a low dose on dopamine but it makes me dizzy.

    Reply

Post a new comment    OR    Read more comments

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Complete drug side effects:

On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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