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Home > Tramadol > Metformin > Tramadol and Metformin

Review: Tramadol and Metformin

This review analyzes the effectiveness and drug interactions between Tramadol and Metformin. It is created by eHealthMe based on reports of 2,649 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Tramadol and Metformin >>>

What are the drugs

Tramadol (latest outcomes from 41,482 users) has active ingredients of tramadol hydrochloride. It is often used in pain.

Trend of tramadol reports

Metformin (latest outcomes from 100,884 users) has active ingredients of metformin hydrochloride. It is often used in diabetes.

Trend of metformin reports

On Oct, 26, 2014: 2,649 people who take Tramadol, Metformin are studied

Tramadol, Metformin outcomes

Drug combinations in study:
- Tramadol (tramadol hydrochloride)
- Metformin (metformin hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol is effective40.00%
(2 of 5 people)
(3 of 5 people)
(5 of 10 people)
(0 of 5 people)
(4 of 12 people)
(3 of 10 people)
(2 of 3 people)
Metformin is effective0.00%
(0 of 1 people)
(3 of 7 people)
(1 of 6 people)
(3 of 9 people)
(4 of 9 people)
(7 of 11 people)
(3 of 7 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Pulmonary EmbolismObsessive-compulsive Personality DisorderMalaiseRenal Failure AcuteAnxietyDiarrhoeaFatiguePain
SomnolencePathological GamblingVomitingThrombosisRenal Failure AcuteBack PainElectrocardiogram Pr ProlongationFatigue
Thrombotic Thrombocytopenic PurpuraHypersexualityNauseaPeripheral Vascular DisorderAggressionCerebrovascular AccidentHyperkalaemiaNausea
Confusional StateEmotional DistressPyrexiaMyocardial InfarctionCerebrovascular AccidentHepatic SteatosisMetabolic AcidosisDyspnoea
Renal Failure AcuteSkin ExfoliationPancreatitis ChronicMydriasisDepressionHyperkalaemiaUrinary Tract InfectionVomiting
KetosisDepressionTendonitisMuscle TwitchingMental DisorderDyspepsiaHyponatraemiaAnaemia
FallSuicidal IdeationBack PainMental DisorderCystConstipationNauseaDiabetes Mellitus
Deep Vein ThrombosisPulmonary EmbolismDyspepsiaDehydrationCardiovascular DisorderWeight DecreasedRunny NoseChest Pain
NauseaRestlessnessWeight DecreasedIliac Artery StenosisLiver Function Test AbnormalMalaiseVomitingDiarrhoea
Drug IneffectiveHypoglycaemiaNight SweatsAmnesiaLiver DisorderMetabolic AcidosisSleepiness - During The DayAsthenia

Drug effectiveness by gender :

Tramadol is effective32.35%
(11 of 34 people)
(8 of 16 people)
Metformin is effective30.30%
(10 of 33 people)
(11 of 17 people)

Most common drug interactions by gender * :

VomitingMyocardial Infarction
Diabetes MellitusDiarrhoea
Pleural EffusionDepression
Chest PainDiabetes Mellitus

Drug effectiveness by age :

Tramadol is effectiven/an/an/a100.00%
(1 of 1 people)
(2 of 11 people)
(3 of 12 people)
(8 of 24 people)
(5 of 24 people)
Metformin is effectiven/an/an/a0.00%
(0 of 1 people)
(1 of 10 people)
(5 of 13 people)
(9 of 25 people)
(6 of 23 people)

Most common drug interactions by age * :

TremorInfluenza Like IllnessBiliary DyskinesiaDyspnoeaDiabetes MellitusDiabetes MellitusNauseaFatigue
Muscular WeaknessJoint SwellingCholecystitis ChronicNauseaType 2 Diabetes MellitusNauseaDepressionAnaemia
Type 2 Diabetes MellitusMyositisGallbladder DisorderDiabetes MellitusDeep Vein ThrombosisPainPainPain
Neoplasm MalignantArthritis BacterialOropharyngeal PainCholelithiasisPainType 2 Diabetes MellitusAnxietyHaemorrhoids
ObesityLethargyHypoglycaemiaCholecystitis ChronicPulmonary EmbolismVomitingMyocardial InfarctionColonic Polyp
LeiomyomaMultiple Drug Overdose AccidentalHypertensionChest PainDiabetic NeuropathyHeadacheDiarrhoeaPleural Effusion
Cerebrovascular AccidentSomnolenceCoughPulmonary EmbolismHeadacheBack PainVomitingGastritis Erosive
OsteoarthritisAccidental Drug Intake By ChildDiabetes MellitusVomitingKetosisChest PainChest PainCystitis
Patellofemoral Pain SyndromeDyshidrosisBack PainNeuropathy PeripheralDiarrhoeaDizzinessHepatic Enzyme Increased
HyperprolactinaemiaBack PainNeck PainDehydrationDyspnoeaArthralgiaNausea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tramadol and Metformin?

You are not alone! Join a related mobile support group:
- support group for people who take Tramadol and Metformin
- support group for people who take Metformin
- support group for people who take Tramadol

Can you answer these questions (Ask a question):

More questions for: Metformin, Tramadol

You may be interested at these reviews (Write a review):

  • Hair loss with metformin hydrochloride usage
    (Posted by a 58 year old woman who has Hair Loss, and takes Metformin Hydrochloride)
    I have been taking the drug Metformin Hydrochloride for about 5 months and definitely find that I am losing hair which is a problem I have never experienced. Always had the healthiest hair, no problems. Well, I am finding that I am losing lair significantly and feel that the manufacturer of this dru ...

  • Ranexa and erectile dysfunction
    (Posted by a 67 year old man who has Metabolic Syndrome, Aortic Valve Replacement, Coronary Artery Disease, and takes Nitrostat, Acyclovir, Gabapentin, Hytrin, Metformin, Aspirin, Isosorbide Mononitrate, Ranexa, Hydrochlorothiazide, Carvedilol, Losartan Potassium)
    I have experienced moderate ED with taking multiple heart and NO meds. This has been manageable and acceptable. Cardiologist added Ranexa (Ranalozine) 3 weeks ago and I am now experiencing complete erectile and ejaculatory failure.

  • Victoza and liver cancer (cholangiocarcinoma)
    (Posted by a 59 year old man who has Anaemia Vitamin B12 Deficiency, Sleep Apnea, Hypertension, Type 2 Diabetes Mellitus, Cholangiocarcinoma (liver Cancer), and takes Diovan, Atenolol, Metformin, Victoza)
    My husband was recently diagnosed with stage 4 liver cancer after taking Victoza for several years. The doctor discontinued the Victoza when the cancer was diagnosed but he actually started feeling better after he stopped it until the cancer started progressing. Since cholangiocarcinoma nd pancreati ...

  • No noticeable effects
    (Posted by a 45 year old woman who has Spinal Stenosis, Degenerative Disc Disease, Spondylosis, End Term Osteoarthritis, and takes Red Panax Ginseng, Tramadol )
    No noticeable effects when used together. Tramadol dose 50-100 mg's four times a day.

  • I wish i had never taken ambien
    (Posted by a 43 year old woman who has Fibromyalgia, and takes Savella, Lyrica, Synthroid, Effexor, Tramadol, Duragesic-50, Flexeril, Ambien)
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered A ...

More reviews for: Metformin, Tramadol

Complete drug side effects:

On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Recent related drug studies (Check your drugs):

More related studies for: Metformin, Tramadol

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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