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Review: Tramadol and Omeprazole

This review analyzes the effectiveness and drug interactions between Tramadol and Omeprazole. It is created by eHealthMe based on 5,761 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

On Mar, 31, 2014: 5,761 people who reported to have interactions when taking Tramadol, Omeprazole are studied

Trend of Tramadol, Omeprazole's drug interactions, side effects and effectiveness reports (8901324)

Drug combinations in study:
- Tramadol (tramadol hydrochloride)
- Omeprazole (omeprazole)

eHealthMe real world results:

Most common interactions experienced by people in the use of Tramadol, Omeprazole:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)2,019
Arthralgia (joint pain)1,995
Anxiety1,863
Vomiting1,825
Asthenia (weakness)1,812
Diarrhoea1,779
Pain1,583
Nausea (feeling of having an urge to vomit)1,410
Fatigue (feeling of tiredness)1,310
Back Pain1,064

Most common interactions experienced by people in long term use of Tramadol, Omeprazole:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Anxiety174
Asthenia (weakness)162
Depression144
Vomiting138
Suicidal Ideation112
Dizziness108
Drug Interaction98
Fatigue (feeling of tiredness)94
Malaise (a feeling of general discomfort or uneasiness)94
Muscle Spasms (muscle contraction)92

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Tramadol0.00%28.12%46.88%25.00%0.00%
Omeprazole0.00%14.81%33.33%33.33%18.52%

Top conditions involved for these people * :

  1. Pain
  2. Rheumatoid arthritis
  3. Hypertension
  4. Depression
  5. Prophylaxis

Top co-used drugs for these people * :

  1. Prilosec
  2. Ultram
  3. Aspirin
  4. Acetaminophen
  5. Prednisone

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Omeprazole, Tramadol

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Complete drug side effects:

On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Omeprazole (omeprazole) is often used to treat gastroesophageal reflux disease. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (1 week ago):

  • Suspicion that general muscle pain is caused by meds. Both Tylenol and Tramadol are taken TID to QID rather than PRN.

    Reply

  • From this study (4 weeks ago):

  • depression, anxiety, adhd, L4-5 black disc with impingement

    Reply

  • From this study (1 month ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness. WBCs run 10.5 to 13.0 consistently. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increased & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

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Can you answer these questions (what is this?):

More questions for: Omeprazole, Tramadol

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    I went into a local emergency room for a sore throat with pustules and difficulty swallowing, i was given Tramadol for pain through my iv. About 2 days later i woke up with a very blistery tongue, which was mildly painful as the day progressed i felt like i had been eating habanero peppers all day.. ...

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    i suffered tonsillitisfor a week. and i lose my weight coz i kept on vomiting. we rushed into my doctor's clinic. he advised me to stay in the hospital for 3 days cause my tonsillitis was really severe. he prescribed me cefuroxime axetil via IV for further absorption and omeprazole via IV for my sto ...

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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