Review: Tramadol and Prozac
Summary: drug interactions are reported among people who take Tramadol and Prozac together.
This review analyzes the effectiveness and drug interactions between Tramadol and Prozac. It is created by eHealthMe based on reports of 1,983 people who take the same drugs from FDA and social media, and is updated regularly.
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Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (view latest outcomes from 41,501 users) Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. (view latest outcomes from 42,269 users)
What are the drugs
Tramadol has active ingredients of tramadol hydrochloride. It is often used in pain. (view latest outcomes from 41,501 users)
Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. (view latest outcomes from 42,269 users)
On Nov, 27, 2014: 1,983 people who take Tramadol, Prozac are studied
Drug combinations in study:
- Tramadol (tramadol hydrochloride)
- Prozac (fluoxetine hydrochloride)
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Tramadol is effective||12.00%|
(3 of 25 people)
(3 of 14 people)
(3 of 12 people)
(3 of 18 people)
(4 of 15 people)
(4 of 10 people)
(3 of 4 people)
(0 of 2 people)
|Prozac is effective||12.50%|
(1 of 8 people)
(6 of 23 people)
(1 of 5 people)
(6 of 20 people)
(8 of 14 people)
(8 of 18 people)
(9 of 15 people)
(1 of 2 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Convulsion||Depression||Convulsion||Convulsion||Oedema Peripheral||Cyanosis||Suicidal Ideation||Nausea|
|Lobar Pneumonia Nos||Anxiety||Tremor||Completed Suicide||Headache||Emotional Distress||Headache||Depression|
|Cardiac Arrest||Condition Aggravated||Menstruation Irregular||Thinking Abnormal||Depression||Peripheral Ischaemia||Somnolence||Fall|
|Drug Toxicity Nos||Emotional Distress||Headache||Hypoglycaemia||Urinary Tract Infection||Pain||Weight Increased||Anxiety|
|Myoclonus||Peripheral Ischaemia||Increased Tendency To Bruise||Insomnia||Fatigue||Arterial Thrombosis||Weight Decreased||Back Pain|
|Hallucination||Cyanosis||Diarrhoea||Circulatory Collapse||Arthralgia||Drug Hypersensitivity||Crying||Headache|
|Hyponatraemia||Cholestasis||Insomnia||Overdose||Acute Myocardial Infarction||Suicide Attempt||Constipation||Dyspnoea|
|Pancreatitis Chronic||Hepatitis||Atrioventricular Block Complete||Headache||Acute Coronary Syndrome||Depression||Abnormal Dreams||Asthenia|
|Balance Disorder||Infection||Conjunctival Haemorrhage||Memory Impairment||Intervertebral Disc Protrusion||Insomnia||Anxiety||Fatigue|
Drug effectiveness by gender :
|Tramadol is effective||17.57%|
(13 of 74 people)
(10 of 26 people)
|Prozac is effective||38.46%|
(30 of 78 people)
(9 of 26 people)
Most common drug interactions by gender * :
Drug effectiveness by age :
|Tramadol is effective||0.00%|
(0 of 1 people)
(0 of 4 people)
(2 of 18 people)
(4 of 63 people)
(9 of 61 people)
(4 of 40 people)
(4 of 13 people)
|Prozac is effective||0.00%|
(0 of 1 people)
(1 of 5 people)
(7 of 20 people)
(5 of 64 people)
(14 of 61 people)
(6 of 43 people)
(6 of 12 people)
Most common drug interactions by age * :
|Blood Chromogranin A Increased||Arterial Thrombosis||Depression||Serotonin Syndrome||Depression||Pain||Depression||Fall|
|Cholecystitis Chronic||Multiple Drug Overdose||Nausea||Depression||Nausea||Pain|
|Gallbladder Disorder||Drug Toxicity||Headache||Nausea||Fall||Asthenia|
|Sphincter Of Oddi Dysfunction||Completed Suicide||Pyrexia||Back Pain||Chest Pain||Diarrhoea|
|Pancreatitis||Drug Ineffective||Drug Dependence||Sinusitis||Hypertension||Dyspnoea|
|Cough||Cholecystitis Chronic||Diabetes Mellitus||Dyspnoea||Asthenia||Vomiting|
* Some reports may have incomplete information.
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- support group for people who take Prozac
- support group for people who take Tramadol
Can you answer these questions (Ask a question):
- Is it safe to take demerol while taking tramadol hydrochloride and hydroxychloroquine (1 answer)
I am experiencing acute, debilitating pain due to the Chikungunya virus, which has reintroduced all of the previous painful symptoms I have,ongoing and in the past, from Fibromyalgia, Arthritis, tendonitis and severe headaches. It's in its 38th day and I am basically crippled from neck to feet. Have to sleep propped up as arms throb with pain when horizontal. The only thing that has subdued the pain slightly are Oxycocet and Ibuprofen, but the pain never goes away. My hands and feet are so inflammed it's difficult to perform even the smallest tasks of personal hygiene and housekeeping. I have difficulty controlling my bladder and often don't make it to the washroom in time. Just started on Demerol today so will no longer take the Oxycocet, but am concerned of the interactions with Demerol, Hydroxychloroquine and Tramadol Hydrochloride extended release tablets that I take daily for the Fibromyalgia and Arthritis. I have dealt with a great deal of pain through the years, but I now have the pain of every serious illness I have had in my lifetime, all at the same time. I honestly didn't think a person could deal with this much pain at once. I have tried and am still taking several vitamins and herbal supplements as well as drinking tons of water and eating really well. Lots of berries, dark vegetables, apples, yogurt and minimal meat. Taking turmeric, papaya leaf, ginger, cinnamon and boswellia for the inflammation. Taking minimal wheat products, sugar and no alcohol. Also, drinking green, fennel and nettle tea daily. I know this is a lot of information, but I really need help and wonder if anyone has any suggestions! Thanking you in advance!!!
- Does anyone experience heart palpitations causedby their acid reflux ?
I have had acid reflux/Gerd for 4 years + Was not believed that symptoms were real for a while as had no heartburn and a diagnosis of Fibromyalgia which even now some medics think is imaginary...it's NOT!!! Following a demeester score of 45 ( very high confirmation of acid reflux) and discovery of a large hiatal hernia, ( a classic physical cause of acid reflux) I had hernia repair operation and LINX anti reflux surgery. Throughout the four years a major symptom of my acid reflux were heart palpatations. They started at the same time I started with reflux and cleared up after the surgery. I have been reflux free palpitation free and antacid free for four months. then I was put on Gabapentin for back spasm and the reflux returned along with the palpitations. Medics keep insisting this is just anxiety yet eat a food that gives me reflux also starts the palps which is the indicator of the reflux as I do not have heartburn. Comes on when relaxing and eating watching tv ( no anxiety present) and when I am sleeping peacefully ( no anxiety present) my heart wakes me up and fires off into tachycardia. Recently a doctor has said it is now known that acid reflux irritates the nerves in the solar plexus area and that triggers the palps. Anyone else experienced this? Are there any studies on it at all? Thanks all.
- I have been having a horrible reaction to tramadol now from the er doctor. what do i do now for pain . i've tried the shots made things even worse. so many trials it's hurts 2 try to gr better ? (3 answers)
Tramadol so been making me so sick from the ER doctor 2 c my doctor if I can hold on. It's a shame ! So many things they keep trying . It's pain not the knew in thing of treating fibromyalgia. Disk problems nerve sciatic. Anxiety u wouldn't believe. I've talked to the FDA
I don't feel safe at all anymore and want to get better . My family gets so upset and we all have lives to live but mine has been on hold 4-5yrs. Just to do the simple things then I have to rest. It's sad . I've always been active . And watch out for Savella !! My god all I would like is to fel better. I can't believe all the things I've read about tramadol it makes me mad that an ER doctor gave it to me first and I told doctors and pain management It wsnt helping. Can't sleep anger horrible thoughts.please I can't do those shots they made things even worse and they don't help me.
- I'm starting 7.5 mg remeron tonight , how can i expect to feal in the morning? (1 answer)
Long period of depression desperate to find something that will work quik and give me some energy.
- Can nuvigil (vs adderall) be used simultaneously to help wean off 60mg/day of adderall? (1 answer)
I have been on Adderall 30mg 2x daily for years!! I've had it lowered to 20mg, I've TRIED to go months without it (when not working) however I feel I've built up a tolerance level to the point that it's not as effective as it once was. My personal life has detoured WAY past anything an ADHD medication can possibly help as far as focusing on NEEDED tasks etc. I end up feeling wrapped up in what I'm doing at the moment that my anxiety increases due to all that I haven't been able to accomplish. I take various medications for various reasons, depression, anxiety, bulimia etc., and for the most part the doses have varied based on circumstances and current need at said time of prescription.. MY FAMILY HAS A HISTORY OF HEART DISEASE, And realizing that I'm already on the highest Adderall dosage scares me (and THEN as I think about it, it makes my heart race!). I've also noticed increased muscle spasms as well as extreme and intense pressure on my jaw (TMJ). MY QUESTION IS: does anyone have any experience LOWERING their Adderall dosage AND adding Nuvigil? The research I've done to date gives me impression that it could help balance out the more extreme effects of Adderall (60mg/day) but that the nuvigil would or could potentially help with the EXTREME exhaustion I feel as Adderall wears off. Some days I just crash, some days I sleep fine and others no matter how hard I tryyyy, I just CAN'T fall asleep, therefore making the next day worse! IDEALLY I'D LIKE TO BE MED FREE, right now I need them, but am hoping maybe I can speak with my doctor to lower Adderall and add Nuvigil to help wean me off the amphetamines as well as lower dosage intake. YES, a lot of the anxiety, sleeplessness and depression are related to current circumstances in my life, however, where I am is not where I want to be or where I'm headed.. Life is a journey, and all my meds have become a part of a journey I never thought I'd find myself taking. I don't want life/meds to define me, or create a me I no longer recognize, because scarily enough that seems to be a common pattern. As I overcome each and every daily obstacle, I also don't want to be "hooked" on my meds or needing "more" to wake up/sleep/function.. I'd like to work on finding a solution towards weaning off my meds NOW, and work my way off slowly, primarily the Adderall. I'm hoping by suggesting to my doctor and showing him my research he may agree (IF ITS EVEN A LOGICAL COMBO, CLEARLY IM NOT A DOCTOR) nuvigil could help me. I've already started taking less of my anti depressants, trazadone and xanax without discussing with doc because he is always busy.. My next appt I want to go in fully prepared with a plan and an overall goal to REDUCE my Adderall dose, but overall, I'm clueless!!! I have no idea what other meds other than nuvigil "could" potentially help if at all. I could be entirely wrong, Anyone with any experience using one vs other or both simultaneously, or anyone with constructive input, PLEASE COMMENT/SHARE!!
You may be interested at these reviews (Write a review):
- A life of depression and fatigue
1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
- Lorazepam nearly killed me during cancer treatment
Day 31 of cold turkey and I want to die. It is a roller coaster from body tics and sweats to rage and crying in one day. I felt so good the 4h day of c/t. It was like before my cancer diagnosis. My bowels are better off Lorazepam. I threw up during bowel movements from the pain. Off Lorazepam first normal bowel movement in over 2 years. Stomach so damaged by Lorazepam that I have absolutely no appetite. I force myself to eat. Neuropathy in hands nearly gone. Feet are better but slower. Lymphedema that appeared after one year on Lorazepam is now gone. I have full range of motion.
- No noticeable effects
No noticeable effects when used together. Tramadol dose 50-100 mg's four times a day.
- Prescribed drugs side effect (1 response)
I have been on these 2 drugs (Gabapentin and Baclofen) prescribed by my gp for osteoarthritis and nerve damage in my full back.Now also suffering from the grief of losing my beloved companion Harvey (dog),I was diagnosed with deep depression. I was given fluoxetine and have been taking this for almost 4 weeks (along with the other 2 meds) and today I have a very sore tongue and it has been white for a number of days,i am going to the pharmacy tomorrow to seek some advice as I am not sure I should be taking all these together? As I am on the highest dose of depression tablets with the fluoxetine I feel it is unsafe to take with the other 2 as the baclofen can also be used to treat certain types of depression. But I can not do without either and as I am allergic to codeine I am pretty much stuck.
- I wish i had never taken ambien
Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.
Comments from related studies:
From this study (4 months ago):
From this study (7 months ago):
Understandably many of these medications/conditions can cause sweating, but I am suffering from generalized sweating upper body chest and head more than under arms or hands or feet. Not localized. Does the androjel if applied to areas of the chest have a 'pore plugging' effect? I feel a film on my skin ~24 hours after application of androjel. When applied to other areas of body, abdomen, the sweating is more severe on chest and shoulders. Thyroid is under control, free testosterone is low normal, Vyvanse is morning only. Tramadol is 50mg qam and prn in late day not more that 3 tablets per day. Fluoxetine is 60mg qam. Not sure if I should consult my endocrinologist or dermatologis for this sweating issue? Is it drug (probably) or something else that is not easily diagnosed because of the drugs that are commonly associated with heavy sweating?
I am a medical professional. Not common man. I have understanding of neuro chemical process and feedback in the body. What questions should be asked so as to not have serious conditions overlooked by obvious issues that might mask.
anonymous1337 on Aug, 19, 2014:
half-ass read this website, but if you're looking for cause of hypnagogic hallucinations, I had mild ones with vyvanse, when I was falling asleep I'd hear chatter, like if I was hearing people talking in a cafeteria, or sometimes, instead of that falling sensation you get when you're falling asleep but not quite? I started hearing a large bang instead of the vertigo sensation. I didn't like vyvanse, I find weed is better at unfucking my head by fucking it from a different angle.
I stopped taking all of these 48 hours ago and think I am experiencing withdrawal
Complete drug side effects:
On eHealthMe, Tramadol (tramadol hydrochloride) is often used to treat pain. Prozac (fluoxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Tramadol is used in:
- Prozac is used in:
Other drugs that are used to treat the same conditions:
- Tramadol alternatives:
- Prozac alternatives:
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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