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Review: Tramadol and Caffeine





Summary: drug interactions are reported among people who take Tramadol and Caffeine together.

This review analyzes the effectiveness and drug interactions between Tramadol and Caffeine. It is created by eHealthMe based on reports of 7 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Tramadol and Caffeine >>>

What are the drugs

Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol hydrochloride 6,864 users)

Caffeine has active ingredients of caffeine. It is often used in fatigue. (latest outcomes from Caffeine 205 users)

On Nov, 25, 2014: 7 people who take Tramadol Hydrochloride, Caffeine are studied

Tramadol Hydrochloride, Caffeine outcomes

Drug combinations in study:
- Tramadol Hydrochloride (tramadol hydrochloride)
- Caffeine (caffeine)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol Hydrochloride is effectiven/an/an/a0.00%
(0 of 3 people)
100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
n/a100.00%
(1 of 1 people)
Caffeine is effectiven/an/an/a0.00%
(0 of 1 people)
50.00%
(1 of 2 people)
n/a0.00%
(0 of 2 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
n/an/an/aMajor DepressionSerotonin SyndromePalpitationsHypomaniaGender Identity Disorder
ArthritisGender Identity DisorderBreathing - Slowed Or Stopped
PtsdBreathing - Slowed Or StoppedHypomania
Insomnia Related To Another Mental ConditionBipolar Ii DisorderBipolar Ii Disorder
Morton's NeuromaOrgasmic Sensation DecreasedOrgasmic Dysfunction
Exhaustion, Fatigue, Lethargy, Tiredness, WearinessLack Of Strength, Muscle Weakness, WeaknessOrgasmic Sensation Decreased
Orgasmic DysfunctionTachycardia
TachycardiaChronic Insomnia
Chronic InsomniaGeneralized Anxiety Disorder
Generalized Anxiety DisorderDizziness

Drug effectiveness by gender :

FemaleMale
Tramadol Hydrochloride is effective50.00%
(2 of 4 people)
0.00%
(0 of 2 people)
Caffeine is effective33.33%
(1 of 3 people)
0.00%
(0 of 2 people)

Most common drug interactions by gender * :

FemaleMale
Bipolar Ii DisorderArthritis
HypomaniaPtsd
Gender Identity DisorderMajor Depression
Orgasmic Sensation DecreasedInsomnia Related To Another Mental Condition
Orgasmic DysfunctionExhaustion, Fatigue, Lethargy, Tiredness, Weariness
Loss Of AppetiteMorton's Neuroma
Lack Of Strength, Muscle Weakness, WeaknessPalpitations
Breathing - Slowed Or Stopped
Tachycardia
Panic Attacks

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tramadol Hydrochloride is effectiven/an/an/a1.52%
(1 of 66 people)
0.00%
(0 of 3 people)
0.00%
(0 of 6 people)
33.33%
(1 of 3 people)
n/a
Caffeine is effectiven/an/an/a0.00%
(0 of 33 people)
0.00%
(0 of 3 people)
0.00%
(0 of 6 people)
50.00%
(1 of 2 people)
n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/an/aGender Identity Disordern/aArthritisSerotonin Syndromen/a
Breathing - Slowed Or StoppedPtsdPalpitations
HypomaniaMajor Depression
Bipolar Ii DisorderInsomnia Related To Another Mental Condition
Orgasmic DysfunctionMorton's Neuroma
Orgasmic Sensation DecreasedExhaustion, Fatigue, Lethargy, Tiredness, Weariness
Tachycardia
Chronic Insomnia
Generalized Anxiety Disorder
Dizziness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tramadol and Caffeine?

You are not alone! Join a related mobile support group:
- support group for people who take Tramadol and Caffeine
- support group for people who take Caffeine
- support group for people who take Tramadol Hydrochloride

Can you answer these questions (Ask a question):

  • In having a-fib, can one use xarelto along with temador for brain tumor treatment
    Both drugs lower platelets, is using Xarelto unwise
  • Can i take diclofenac sodium mispoprostol with tramadol hcl?
    I have bad arthritis in my hips - very painful and affecting my quality of life. My doctor like to prescribe pills. He has given me Diclofenac Sodium Mispoprostal and Tramadol HCL. I have experienced minimal side effects i.e.: drowsiness but thats about it. I just want to be sure that I can take these drugs together.
  • Is it safe to take demerol while taking tramadol hydrochloride and hydroxychloroquine (2 answers)
    I am experiencing acute, debilitating pain due to the Chikungunya virus, which has reintroduced all of the previous painful symptoms I have,ongoing and in the past, from Fibromyalgia, Arthritis, tendonitis and severe headaches. It's in its 38th day and I am basically crippled from neck to feet. Have to sleep propped up as arms throb with pain when horizontal. The only thing that has subdued the pain slightly are Oxycocet and Ibuprofen, but the pain never goes away. My hands and feet are so inflammed it's difficult to perform even the smallest tasks of personal hygiene and housekeeping. I have difficulty controlling my bladder and often don't make it to the washroom in time. Just started on Demerol today so will no longer take the Oxycocet, but am concerned of the interactions with Demerol, Hydroxychloroquine and Tramadol Hydrochloride extended release tablets that I take daily for the Fibromyalgia and Arthritis. I have dealt with a great deal of pain through the years, but I now have the pain of every serious illness I have had in my lifetime, all at the same time. I honestly didn't think a person could deal with this much pain at once. I have tried and am still taking several vitamins and herbal supplements as well as drinking tons of water and eating really well. Lots of berries, dark vegetables, apples, yogurt and minimal meat. Taking turmeric, papaya leaf, ginger, cinnamon and boswellia for the inflammation. Taking minimal wheat products, sugar and no alcohol. Also, drinking green, fennel and nettle tea daily. I know this is a lot of information, but I really need help and wonder if anyone has any suggestions! Thanking you in advance!!!
  • Does anyone experience heart palpitations causedby their acid reflux ?
    I have had acid reflux/Gerd for 4 years + Was not believed that symptoms were real for a while as had no heartburn and a diagnosis of Fibromyalgia which even now some medics think is imaginary...it's NOT!!! Following a demeester score of 45 ( very high confirmation of acid reflux) and discovery of a large hiatal hernia, ( a classic physical cause of acid reflux) I had hernia repair operation and LINX anti reflux surgery. Throughout the four years a major symptom of my acid reflux were heart palpatations. They started at the same time I started with reflux and cleared up after the surgery. I have been reflux free palpitation free and antacid free for four months. then I was put on Gabapentin for back spasm and the reflux returned along with the palpitations. Medics keep insisting this is just anxiety yet eat a food that gives me reflux also starts the palps which is the indicator of the reflux as I do not have heartburn. Comes on when relaxing and eating watching tv ( no anxiety present) and when I am sleeping peacefully ( no anxiety present) my heart wakes me up and fires off into tachycardia. Recently a doctor has said it is now known that acid reflux irritates the nerves in the solar plexus area and that triggers the palps. Anyone else experienced this? Are there any studies on it at all? Thanks all.
  • I have been having a horrible reaction to tramadol now from the er doctor. what do i do now for pain . i've tried the shots made things even worse. so many trials it's hurts 2 try to gr better ? (3 answers)
    Tramadol so been making me so sick from the ER doctor 2 c my doctor if I can hold on. It's a shame ! So many things they keep trying . It's pain not the knew in thing of treating fibromyalgia. Disk problems nerve sciatic. Anxiety u wouldn't believe. I've talked to the FDA
    I don't feel safe at all anymore and want to get better . My family gets so upset and we all have lives to live but mine has been on hold 4-5yrs. Just to do the simple things then I have to rest. It's sad . I've always been active . And watch out for Savella !! My god all I would like is to fel better. I can't believe all the things I've read about tramadol it makes me mad that an ER doctor gave it to me first and I told doctors and pain management It wsnt helping. Can't sleep anger horrible thoughts.please I can't do those shots they made things even worse and they don't help me.

More questions for: Caffeine, Tramadol Hydrochloride

You may be interested at these reviews (Write a review):

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    No noticeable effects when used together. Tramadol dose 50-100 mg's four times a day.
  • I wish i had never taken ambien
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.
  • Horrific nightmares taking naproxen
    I've Taking naproxen 500mg twice a day for 3 weeks on a course for 6 months, I've been having horrific dreams worse than horrer movies, the most recent is involving my ex & current partner where I had a psychotic stalker (my ex) switched around because in the dream I dump my partner for my ex, well the things that have been going on in my dreams are scary to the point I've woken up screaming/ crying, body is covered in sweat & it's stopping me from sleeping more, I get around 2 hours sleep a night off them..... I mean dripping, this dream was so horrific I had to post a review which I woke up around 15 mins ago, I have nightmares quiet often but never this bad
  • Burning mouth syndrome
    I went into a local emergency room for a sore throat with pustules and difficulty swallowing, i was given Tramadol for pain through my iv. About 2 days later i woke up with a very blistery tongue, which was mildly painful as the day progressed i felt like i had been eating habanero peppers all day.. Quite painful. No matter what i tried to eat, including popsicles.. It felt as if i was eating habaneros on a stick with a side of glass shards.. Apparently all you can do is wait the darn syndrome out... I still have a blistered tongue 2 weeks later but the pain is still there. Im now on a liquid version of norco, it numbs the pain for a little while, im able to eat and taste some foods again, which is nice and a lot better than a liquid diet.

More reviews for: Caffeine, Tramadol Hydrochloride

Comments from related studies:

  • From this study (8 months ago):

  • Severity level**

    Reply

  • From this study (8 months ago):

  • I was in three car accidents, one in which my head was turned and I got rear ended from behind that was when all the pain issues started along with the percocet prescription. I didn't intially use the script but later on in the years I started to develop alot more pain after being hit in two more whip lash car accidents in which my car was written off. I had a death of my parent only two months after the last accident and thats when I started to take more pain medication then prescribed. I have always had issues with my moods, I remember having a panic attack after a break-up with my long term boyfriend when I was 25 and going to a walk in clinic and them giving me effexor 75mg which worked great at that time, a little too great since I couldn't cry and eventually tried to overdose when the newest relationship I got myself involved in was to a married man and unhealthy. I kept off meds for sometime after that but found myself more stressed when I was 27 after my long term bf had an affair with my cousin and had two kids with her, I was left with a house in my name that was just bought 9 months prior and no job due to my pain issues. I started on wellbutrin 150xl then and virpo acid, which I didn't feel was working but looking back maybe it was. I have taken wellbturin more then 3 times since and everytime I Was very irritable and had to go off. I tried many other pills and I"m getting so fustrated. I really wish I had some answers, MY biggest complaint is that I"m always tired, which makes me depressed and in more pain. and then I find I'm abusing adderal or other stimulants to stay awake longer and then at night can't sleep. I was hospitalized and went through detox on my own in feb of this year. only to come out of the hospital on celexa 20mg and fight with the current bf over counserlling issues and break up and end up dating for 2 weeks a guy i met in hospital all in which time I relapsed. I am just a whits end. Please any advice would be great

    Reply

    Snood on May, 1, 2013:

    1. No romantic relationships for six months to a year
    2. Research the word "Codependent" and engage in some loving and gentle introspection.
    3. Join a group called "CODA"

    Reply

    Jim on Apr, 27, 2014:

    I would add to seek some counselling

    Reply

Complete drug side effects:

On eHealthMe, Tramadol Hydrochloride (tramadol hydrochloride) is often used to treat pain. Caffeine (caffeine) is often used to treat fatigue. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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