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Review: taking Tramadol and Gabapentin together

Summary: drug interactions are reported among people who take Tramadol and Gabapentin together.

This review analyzes the effectiveness and drug interactions between Tramadol and Gabapentin. It is created by eHealthMe based on reports of 5,335 people who take the same drugs from FDA and social media, and is updated regularly.


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On Apr, 13, 2015: 5,335 people who take Tramadol Hydrochloride, Gabapentin are studied

Tramadol Hydrochloride, Gabapentin outcomes

Drug combinations in study:
- Tramadol Hydrochloride (tramadol hydrochloride)
- Gabapentin (gabapentin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol Hydrochloride is effective10.00%
(2 of 20 people)
(10 of 60 people)
(8 of 43 people)
(14 of 69 people)
(18 of 60 people)
(11 of 32 people)
(6 of 10 people)
(1 of 4 people)
Gabapentin is effective20.69%
(6 of 29 people)
(13 of 71 people)
(9 of 45 people)
(12 of 49 people)
(20 of 70 people)
(12 of 26 people)
(5 of 8 people)
(1 of 3 people)

Drug effectiveness by gender :

Tramadol Hydrochloride is effective23.98%
(53 of 221 people)
(16 of 73 people)
Gabapentin is effective29.07%
(66 of 227 people)
(12 of 73 people)

Drug effectiveness by age :

Tramadol Hydrochloride is effectiven/an/a33.33%
(1 of 3 people)
(5 of 49 people)
(10 of 140 people)
(20 of 172 people)
(14 of 125 people)
(19 of 111 people)
Gabapentin is effectiven/an/a66.67%
(2 of 3 people)
(6 of 49 people)
(14 of 139 people)
(27 of 164 people)
(17 of 127 people)
(12 of 112 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Confusional StatePainDizzinessPainAnxietyConvulsionHeadachePain
SomnolenceFatigueInsomniaDepressionDepressionLoss Of ConsciousnessInsomniaAnxiety
HeadacheDrug IneffectiveDepressionAnxietySuicide AttemptAccidental OverdoseFeeling AbnormalNausea
TremorDepressionSomnolenceChest PainPainDrug Withdrawal SyndromeHypopituitarismDepression
RashConfusional StateDrug IneffectiveFatigueChest PainRetchingIntervertebral Disc DisorderFatigue
Hallucination, VisualSomnolenceMuscle TwitchingDrug IneffectiveSuicidal IdeationFeeling Of Body Temperature ChangeMuscular WeaknessDyspnoea
DizzinessArthralgiaMyoclonusDrug DependenceDrug IneffectiveMuscle SpasmsDrug IneffectiveFall
AnxietyFeeling HotNauseaArthritisCompleted SuicideCerebrovascular AccidentNosebleedBack Pain
Pain In ExtremityDisorientationDisorientationDizzinessLoss Of ConsciousnessHypoaesthesiaAdrenal DisorderHeadache
NauseaDizzinessLoss Of ConsciousnessMalaisePneumoniaSwellingAgitationDizziness

Most common drug interactions by gender * :

FallDrug Ineffective
Pain In ExtremityChest Pain
Back PainBack Pain

Most common drug interactions by age * :

Type 2 Diabetes MellitusInsomniaConfusional StatePainDepressionPainNauseaFall
Patellofemoral Pain SyndromeSweat Gland DisorderFlushingInsomniaAnxietyDepressionPainPain
OsteoarthritisDyspnoeaRashHeadacheDrug IneffectiveAnxietyAnxietyDyspnoea
ObesityFeeling AbnormalHallucination, VisualDepressionHeadacheHeadacheDepressionFatigue
LeiomyomaChest PainSuicidal IdeationDizzinessNauseaBack PainInsomniaNausea
Stress FractureMyositisTremorAnxietyDyspnoeaFatigueArthralgiaBack Pain
HaematomaArthritis BacterialHeadacheAbdominal DistensionDizzinessArthralgiaFatigueAnxiety
Foetal Exposure During PregnancyInfluenza Like IllnessEmotional DistressFeeling HotDrug Withdrawal SyndromeNauseaVomitingAnaemia
Premature Separation Of PlacentaJoint SwellingVomitingFatigueDrug DependenceChest PainDiarrhoeaPain In Extremity
Maternal Drugs Affecting FoetusCardio-respiratory ArrestFebrile NeutropeniaDrug IneffectivePainMuscle SpasmsPain In ExtremityAsthenia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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- support group for people who take Gabapentin
- support group for people who take Tramadol Hydrochloride

Recent related drug studies (Check your drugs):

Complete drug side effects:

On eHealthMe, Tramadol Hydrochloride (tramadol hydrochloride) is often used to treat pain. Gabapentin (gabapentin) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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