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Review: Tramadol and Oxycodone





Summary: drug interactions are reported among people who take Tramadol and Oxycodone together.

This review analyzes the effectiveness and drug interactions between Tramadol and Oxycodone. It is created by eHealthMe based on reports of 1,818 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Tramadol and Oxycodone >>>

What are the drugs

Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol hydrochloride 6,864 users)

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. (latest outcomes from Oxycodone 27,269 users)

On Nov, 26, 2014: 1,818 people who take Tramadol Hydrochloride, Oxycodone are studied

Tramadol Hydrochloride, Oxycodone outcomes

Drug combinations in study:
- Tramadol Hydrochloride (tramadol hydrochloride)
- Oxycodone (oxycodone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol Hydrochloride is effective16.67%
(1 of 6 people)
0.00%
(0 of 7 people)
20.00%
(1 of 5 people)
28.57%
(2 of 7 people)
0.00%
(0 of 4 people)
0.00%
(0 of 5 people)
0.00%
(0 of 2 people)
n/a
Oxycodone is effective40.00%
(4 of 10 people)
44.44%
(4 of 9 people)
60.00%
(3 of 5 people)
57.14%
(4 of 7 people)
0.00%
(0 of 3 people)
33.33%
(1 of 3 people)
25.00%
(1 of 4 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
AnxietyDrug DependenceDrug DependenceDrug Withdrawal SyndromeDrug Withdrawal SyndromeLoss Of ConsciousnessShunt StenosisPain
Renal Failure AcuteNauseaDrug Withdrawal SyndromePainDepressionConvulsionChronic PainNausea
ConvulsionDepressionDepressionAnxietyDrug DependenceLumbar Vertebral FractureShort-term Memory LossAnxiety
Chest PainDrug IneffectivePainDrug DependenceAstheniaFractured CoccyxFoot PainDepression
SinusitisSuicidal IdeationDrug IneffectiveDrug IneffectiveAnxietyAnxietyAnxietyHeadache
HeadacheInsomniaNauseaAffect LabilityInsomniaDiscomfortShortness Of BreathDyspnoea
Confusional StateDizzinessAnxietyAnhedoniaPain In ExtremityMuscle SpasmsHeadacheAsthenia
HypoxiaDrug AddictionHeadacheChest PainDrug IneffectiveFractured SacrumHair ThinningFatigue
PneumoniaConfusional StateDizzinessPyrexiaBack PainSomnolenceIrritabilityFall
NauseaDisturbance In AttentionSuicidal IdeationRoad Traffic AccidentNauseaSelf Injurious BehaviourAngerVomiting

Drug effectiveness by gender :

FemaleMale
Tramadol Hydrochloride is effective13.04%
(3 of 23 people)
7.69%
(1 of 13 people)
Oxycodone is effective46.43%
(13 of 28 people)
33.33%
(4 of 12 people)

Most common drug interactions by gender * :

FemaleMale
PainDepression
AnxietyNausea
NauseaPain
DepressionAnxiety
HeadacheDrug Dependence
ArthralgiaDyspnoea
FatigueVomiting
FallBack Pain
AstheniaDrug Withdrawal Syndrome
AnaemiaAsthenia

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tramadol Hydrochloride is effectiven/an/an/a22.22%
(2 of 9 people)
0.00%
(0 of 15 people)
4.76%
(1 of 21 people)
8.33%
(1 of 12 people)
0.00%
(0 of 5 people)
Oxycodone is effectiven/an/an/a37.50%
(3 of 8 people)
40.00%
(6 of 15 people)
13.64%
(3 of 22 people)
13.33%
(2 of 15 people)
27.27%
(3 of 11 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aRespiratory ArrestVomitingNauseaDrug DependencePainAnxietyPain
Accidental Drug Intake By ChildOverdose NosPainDepressionDepressionPainDyspnoea
Cardiac ArrestCardiopulmonary FailureRespiratory ArrestAnxietyAnxietyNauseaNausea
Drug ToxicityDrug ToxicityHeadacheNauseaNauseaInsomniaFatigue
DeathCellulitisDrug AbuseDrug Withdrawal SyndromeDrug DependenceFallAsthenia
Unresponsive To StimuliPyrexiaCardiac ArrestHeadacheHeadacheDepressionAnxiety
SomnolenceNeurotoxicityDrug Withdrawal SyndromeDrug IneffectiveChest PainArthralgiaWeight Decreased
Drug AbuseNeutropeniaDrug DependenceChest PainBack PainWeight DecreasedFall
PoisoningHemiparesisAnxietyDizzinessInsomniaAnaemiaVomiting
DehydrationDepressionAstheniaVomitingDrug Withdrawal SyndromeAnaemia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tramadol and Oxycodone?

You are not alone! Join a related mobile support group:
- support group for people who take Tramadol and Oxycodone
- support group for people who take Oxycodone
- support group for people who take Tramadol Hydrochloride

Can you answer these questions (Ask a question):

  • Is it safe to take demerol while taking tramadol hydrochloride and hydroxychloroquine (1 answer)
    I am experiencing acute, debilitating pain due to the Chikungunya virus, which has reintroduced all of the previous painful symptoms I have,ongoing and in the past, from Fibromyalgia, Arthritis, tendonitis and severe headaches. It's in its 38th day and I am basically crippled from neck to feet. Have to sleep propped up as arms throb with pain when horizontal. The only thing that has subdued the pain slightly are Oxycocet and Ibuprofen, but the pain never goes away. My hands and feet are so inflammed it's difficult to perform even the smallest tasks of personal hygiene and housekeeping. I have difficulty controlling my bladder and often don't make it to the washroom in time. Just started on Demerol today so will no longer take the Oxycocet, but am concerned of the interactions with Demerol, Hydroxychloroquine and Tramadol Hydrochloride extended release tablets that I take daily for the Fibromyalgia and Arthritis. I have dealt with a great deal of pain through the years, but I now have the pain of every serious illness I have had in my lifetime, all at the same time. I honestly didn't think a person could deal with this much pain at once. I have tried and am still taking several vitamins and herbal supplements as well as drinking tons of water and eating really well. Lots of berries, dark vegetables, apples, yogurt and minimal meat. Taking turmeric, papaya leaf, ginger, cinnamon and boswellia for the inflammation. Taking minimal wheat products, sugar and no alcohol. Also, drinking green, fennel and nettle tea daily. I know this is a lot of information, but I really need help and wonder if anyone has any suggestions! Thanking you in advance!!!
  • Does anyone experience heart palpitations causedby their acid reflux ?
    I have had acid reflux/Gerd for 4 years + Was not believed that symptoms were real for a while as had no heartburn and a diagnosis of Fibromyalgia which even now some medics think is imaginary...it's NOT!!! Following a demeester score of 45 ( very high confirmation of acid reflux) and discovery of a large hiatal hernia, ( a classic physical cause of acid reflux) I had hernia repair operation and LINX anti reflux surgery. Throughout the four years a major symptom of my acid reflux were heart palpatations. They started at the same time I started with reflux and cleared up after the surgery. I have been reflux free palpitation free and antacid free for four months. then I was put on Gabapentin for back spasm and the reflux returned along with the palpitations. Medics keep insisting this is just anxiety yet eat a food that gives me reflux also starts the palps which is the indicator of the reflux as I do not have heartburn. Comes on when relaxing and eating watching tv ( no anxiety present) and when I am sleeping peacefully ( no anxiety present) my heart wakes me up and fires off into tachycardia. Recently a doctor has said it is now known that acid reflux irritates the nerves in the solar plexus area and that triggers the palps. Anyone else experienced this? Are there any studies on it at all? Thanks all.
  • I have been having a horrible reaction to tramadol now from the er doctor. what do i do now for pain . i've tried the shots made things even worse. so many trials it's hurts 2 try to gr better ? (3 answers)
    Tramadol so been making me so sick from the ER doctor 2 c my doctor if I can hold on. It's a shame ! So many things they keep trying . It's pain not the knew in thing of treating fibromyalgia. Disk problems nerve sciatic. Anxiety u wouldn't believe. I've talked to the FDA
    I don't feel safe at all anymore and want to get better . My family gets so upset and we all have lives to live but mine has been on hold 4-5yrs. Just to do the simple things then I have to rest. It's sad . I've always been active . And watch out for Savella !! My god all I would like is to fel better. I can't believe all the things I've read about tramadol it makes me mad that an ER doctor gave it to me first and I told doctors and pain management It wsnt helping. Can't sleep anger horrible thoughts.please I can't do those shots they made things even worse and they don't help me.
  • Can you loose weight while taking hydroxyzine?
    Hydroxyzine has been my life saver but I have noticed a gradual increase in weight. My blood pressure has also gone up. I don't have the increased hunger but what scares me is I am not eating more than I normally do. I do not eat breakfast. I have a Glucerna at lunch and then dinner, protein potatoes/rice and veggies, sometimes pasta nothing huge and a snack at night. Maybe a small bowl of ice cream but not every night. I do not drink soda, lots of water and with dinner a large glass of apple juice. I have noticed every year I put on a little bit more weight. I was tested for my thyroid and it is normal. I haven't started an avid work out program. Doing high intense impact will not work due to my IC. I would like to try power walking. Anyone else experience any of these issues?
  • What does emphysemic change in the lungs mean (1 answer)
    Doctor told me I have emphysema changes in my lungs.could this be causing my nausea every day all day?

More questions for: Oxycodone, Tramadol Hydrochloride

You may be interested at these reviews (Write a review):

  • Mensis cycle and oxycontin
    I have severe back injuries. When I lived in another state, I was put on oxycontin and immediately my menstrual cycle (period] stopped for 1 year. When I moved to another state, I stopped taking this drug and my period returned normal. I eventually had to go back on this drug, (oxycontin) and since this time, 2 years now, I again have not had a period since beginning. If you are on this drug and are worried about your period stopping, fear not, it is a normal side effect. Hope this helps. ..
  • No noticeable effects
    No noticeable effects when used together. Tramadol dose 50-100 mg's four times a day.
  • Which issue has caused my periodontitis, my fibromyalgia or spinal stenosis? (2 responses)
    At the age of 38 yrs old, I was diagnosed with Fibromyalgia and Spinal Stenosis. Obviously I had both of the disease for some years, and was struggling with the pain and symptoms for some time before I finally got checked, went through years being told they didn't find anything, told I had Herniated disks in My back only. Now with all the findings, there are 7 Herniated disks from My neck to My lower back.
    Also since 2010, I was diagnosed with Periodontitis and have been losing all of My teeth in the top of My mouth.
    I am 44 yrs old now, have been on disability for the last 4 years. I am down to 6 teeth in the top of My mouth, since having 1 removed just last week. They are telling Me that 3 more need to come out, and I am trying not to sink into total depression, especially since these are now My front teeth. I have a appointment today for a Denture Exam.

    I started researching today to see if this Periodontitis is related to either My Spinal Stenosis or My Fibromyalgia. Especially since I once again looked up the definition for Periodontitis. Which States;

    **Periodontal Disease and Bone Health. Periodontitis is a chronic infection that affects the gums and the bones that support the teeth. Bacteria and the body's own immune system break down the bone and connective tissue that hold teeth in place.

    Of course with My disease of Spinal Stenosis and the bone loss as well as the nerve narrowing, I thought the breaking down of the bone in the gums might have a connection. Research didnt find any linking.

    Now with Fibromyalgia, research showed 6 out of 17 thousand that they found. LOL Wow.. Well I guess I am "Number 7". Lucky Me! But it does make more sense now that looking at the definition. It is a Chronic infection (which Fibromyalia does create these) that effects the gums and bones. Bacteria and The Body's own Immune System break down the bone and connective tissue that hold the teeth. Which with Fibromyalgia, our Immune System is always all kinds of "Crazy"!

    Oh course you can not have any of these diseases, or any other health issues and wind up with Periodontitis. It happens. But I know from lots of reading, researching and living with Fibromyalgia, that it is "Very Possible"!

    I would sure like to know what others with these 2 diseases are experiencing.
    Have a Blessed Day.
  • I wish i had never taken ambien
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.
  • Who cares about the patient? (1 response)
    I can't believe I'm still alive but quality of life is greatly diminished and no one cares. Not one doctor cares about how this one dr. prescribed all these drugs over a period of 5 years and I lost everything. I flat-lined sept 18, 2005 and was told by dr there in er that I would live 1-5 years and I had just lost my job as letter-carrier of over 17 years and my daughter was killed in dec of 2000, which I will always feel great responsibility because I knew I should have called her, it would have saved her life as she was killed in the firdale village apt fire and she didn't live there, she lived with me she was only 20 years old. So this crappy dr steven a creelman of seattle just kept throwing pills at me, telling me there was nothing wrong with any of the pills just me. I feared dr's and still do, I know they are just people and most people are good and caring but a lot are not. The Celebrex started after I was hit by a truck on the job in march of 2000. I will admit it relieved some pain but I had side affects immediately, within days to weeks. I was told by the crappy dr to shut up and take them as he originally told me they were not anti-inflamatorys but a new drug that did not upset stomach but they did. I felt trapped because it was an L&I and I didn't want to lose my job and so healthy and strong figured w/PT and rest I could overcome the accident pain which was lower back and neck well I couldn't sleep from pain and stomach but I couldn't tell crappy dr it would do no good. My daughter was killed Christmas night and that's a very hard one. I went back to work because my job was most of my life and I had friends at work. I continued to have more problems from Celebrex and I thought my stomach was on fire, it was blood clots that broke lose and I had to have an operation on my small instestine and what was worse is creelman, the crappy dr, when he told me it was an emergency umbililical hernia I told him I was going to get papers from owcp DOL as I would be off work at least 6 weeks. He said NO!!!!!!!!!! He closed the door and told me no, no I won't say it's from Celebrex when He really did know it was. I had an endoscopy 6 months later and that specialist said no more Celebrex. After that operation I just never felt good again I was swelling up my legs etc and fatique all kinds of not feeling good things and I was pissed at the crappy dr who by the said to me that no other dr would diagnose any different or believe me. So, it was in July of 04 and I was so sick I just went in there andhe was on vaction so another dr ran a bunch of blood tests for hiv which I told her was impossible and lupus and a few other things but no one there looked at any of the drugs except the pain medication which ironically was one of the only ones that didn't contribute to dvt & PE. when creelman got back I was still so sick I had left work and said I would be back in 2 weeks after I had some PT and rest. I couldn't sleep. That's when he prescribed REMERON. It was for sleep which it did help but I gained 50 lbs and within a couple months acquired tonsillitis, bhroinchitis, pneumonia, Phlebitis and a dvt which instead of referring me to a specialist he just presibed me an anti-inflammatory and another anti-depressant plus all the drugs He gave tons of samples which were never in noted in my files. I think he should have to pay me MONEY!! I have none since I have no job and I feel so terrible I wish I could just have my job back. And my Daughter but my health has been a Hematologist and injectable blood thinners. I hate the state of wash medical care about doctors but not the patients and I have no money to sue and it has been my experience not to mention crappy doctor SO WHO DO THE PATIENTS THAT ARE BADLY AFFECTED BY CRAPPY DCTORS GO TO? Oh I also couldn't be in the class-action suit because I didn't flat-line from heart attack. REALLY?

More reviews for: Oxycodone, Tramadol Hydrochloride

Comments from related studies:

  • From this study (2 months ago):

  • Possible stomach blockage, pharmaceutical bezoar.
    Oxycontin 30 mg every 12 hours is far less effective than oxycodone 15 mg every 6 hours.

    Reply

  • From this study (1 year ago):

  • after taking tramadol i expeeienced pain in knee diagnosis bakera cyst

    Reply

  • From this study (1 year ago):

  • cervical disc and fusion c 5/6, other herniations spurring etc

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Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Tramadol Hydrochloride (tramadol hydrochloride) is often used to treat pain. Oxycodone (oxycodone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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