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Review: Tramadol and Suboxone





Summary: drug interactions are reported among people who take Tramadol and Suboxone together.

This review analyzes the effectiveness and drug interactions between Tramadol and Suboxone. It is created by eHealthMe based on reports of 52 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Tramadol and Suboxone >>>

What are the drugs

Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol hydrochloride 6,864 users)

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. (latest outcomes from Suboxone 8,267 users)

On Dec, 3, 2014: 52 people who take Tramadol Hydrochloride, Suboxone are studied

Tramadol Hydrochloride, Suboxone outcomes

Drug combinations in study:
- Tramadol Hydrochloride (tramadol hydrochloride)
- Suboxone (buprenorphine hydrochloride; naloxone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol Hydrochloride is effectiven/a0.00%
(0 of 1 people)
n/a0.00%
(0 of 1 people)
33.33%
(1 of 3 people)
n/an/an/a
Suboxone is effective50.00%
(1 of 2 people)
100.00%
(1 of 1 people)
n/a100.00%
(3 of 3 people)
n/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
SomnolenceWithdrawal SyndromeDrug Exposure During PregnancySeizuresn/an/an/aFall
Psychomotor HyperactivityHallucinationGrand Mal ConvulsionSyncope
Feeling JitteryPainAnaemia
DeathPulmonary OedemaPain
Feeling AbnormalMigraineWeight Decreased
Hepatic SteatosisOverdoseSpinal Osteoarthritis
ObesitySeizuresVomiting
Cardiac HypertrophyRapid Heart BeatGastritis
Renal ArteriosclerosisConfusionConfusional State
Rapid Heart BeatVomitingAsthenia

Drug effectiveness by gender :

FemaleMale
Tramadol Hydrochloride is effective25.00%
(1 of 4 people)
0.00%
(0 of 1 people)
Suboxone is effective80.00%
(4 of 5 people)
100.00%
(1 of 1 people)

Most common drug interactions by gender * :

FemaleMale
ConvulsionFall
Loss Of ConsciousnessSinusitis
SomnolencePulmonary Embolism
PainOesophagitis
Multiple Drug OverdoseAsthenia
HeadacheAtrial Fibrillation
Drug AbuseVomiting
FallCerebrovascular Accident
NauseaPancytopenia
Oedema PeripheralLoose Tooth

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tramadol Hydrochloride is effectiven/an/an/a25.00%
(1 of 4 people)
0.00%
(0 of 1 people)
n/an/an/a
Suboxone is effectiven/an/an/a100.00%
(3 of 3 people)
100.00%
(2 of 2 people)
0.00%
(0 of 4 people)
n/an/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aDrug ToxicityGrand Mal ConvulsionConvulsionPulmonary OedemaDrug IneffectiveDecreased Appetite
Drug Screen PositiveDrug Exposure During PregnancyLoss Of ConsciousnessWithdrawal SyndromeDrug Withdrawal SyndromeCataract
Accidental OverdoseOverdoseHeadachePainVomitingOrthostatic Hypotension
MigraineDrug AbuseHallucinationPain In ExtremityGastritis
VomitingMultiple Drug OverdoseAgitationGastrointestinal DisorderSpinal Osteoarthritis
SeizuresDrug DependenceDrug ToxicityBack PainSupraventricular Extrasystoles
SomnolenceCompleted SuicideDelusional PerceptionLoose Tooth
DyskinesiaDepressionFallAsthenia
Head InjuryDrug Withdrawal SyndromePainAtrial Fibrillation
LethargyPulmonary CongestionBalance DisorderCerebrovascular Accident

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tramadol and Suboxone?

You are not alone! Join a related mobile support group:
- support group for people who take Tramadol and Suboxone
- support group for people who take Suboxone
- support group for people who take Tramadol Hydrochloride

Can you answer these questions (Ask a question):

  • Is it okay to take 15mg. of remeron also known as mirtazapine
    is it safe to take suboxone with remeron because I am having a panic attack
  • Is it safe to take demerol while taking tramadol hydrochloride and hydroxychloroquine (2 answers)
    I am experiencing acute, debilitating pain due to the Chikungunya virus, which has reintroduced all of the previous painful symptoms I have,ongoing and in the past, from Fibromyalgia, Arthritis, tendonitis and severe headaches. It's in its 38th day and I am basically crippled from neck to feet. Have to sleep propped up as arms throb with pain when horizontal. The only thing that has subdued the pain slightly are Oxycocet and Ibuprofen, but the pain never goes away. My hands and feet are so inflammed it's difficult to perform even the smallest tasks of personal hygiene and housekeeping. I have difficulty controlling my bladder and often don't make it to the washroom in time. Just started on Demerol today so will no longer take the Oxycocet, but am concerned of the interactions with Demerol, Hydroxychloroquine and Tramadol Hydrochloride extended release tablets that I take daily for the Fibromyalgia and Arthritis. I have dealt with a great deal of pain through the years, but I now have the pain of every serious illness I have had in my lifetime, all at the same time. I honestly didn't think a person could deal with this much pain at once. I have tried and am still taking several vitamins and herbal supplements as well as drinking tons of water and eating really well. Lots of berries, dark vegetables, apples, yogurt and minimal meat. Taking turmeric, papaya leaf, ginger, cinnamon and boswellia for the inflammation. Taking minimal wheat products, sugar and no alcohol. Also, drinking green, fennel and nettle tea daily. I know this is a lot of information, but I really need help and wonder if anyone has any suggestions! Thanking you in advance!!!
  • Does anyone experience heart palpitations causedby their acid reflux ?
    I have had acid reflux/Gerd for 4 years + Was not believed that symptoms were real for a while as had no heartburn and a diagnosis of Fibromyalgia which even now some medics think is imaginary...it's NOT!!! Following a demeester score of 45 ( very high confirmation of acid reflux) and discovery of a large hiatal hernia, ( a classic physical cause of acid reflux) I had hernia repair operation and LINX anti reflux surgery. Throughout the four years a major symptom of my acid reflux were heart palpatations. They started at the same time I started with reflux and cleared up after the surgery. I have been reflux free palpitation free and antacid free for four months. then I was put on Gabapentin for back spasm and the reflux returned along with the palpitations. Medics keep insisting this is just anxiety yet eat a food that gives me reflux also starts the palps which is the indicator of the reflux as I do not have heartburn. Comes on when relaxing and eating watching tv ( no anxiety present) and when I am sleeping peacefully ( no anxiety present) my heart wakes me up and fires off into tachycardia. Recently a doctor has said it is now known that acid reflux irritates the nerves in the solar plexus area and that triggers the palps. Anyone else experienced this? Are there any studies on it at all? Thanks all.
  • I have been having a horrible reaction to tramadol now from the er doctor. what do i do now for pain . i've tried the shots made things even worse. so many trials it's hurts 2 try to gr better ? (3 answers)
    Tramadol so been making me so sick from the ER doctor 2 c my doctor if I can hold on. It's a shame ! So many things they keep trying . It's pain not the knew in thing of treating fibromyalgia. Disk problems nerve sciatic. Anxiety u wouldn't believe. I've talked to the FDA
    I don't feel safe at all anymore and want to get better . My family gets so upset and we all have lives to live but mine has been on hold 4-5yrs. Just to do the simple things then I have to rest. It's sad . I've always been active . And watch out for Savella !! My god all I would like is to fel better. I can't believe all the things I've read about tramadol it makes me mad that an ER doctor gave it to me first and I told doctors and pain management It wsnt helping. Can't sleep anger horrible thoughts.please I can't do those shots they made things even worse and they don't help me.
  • Can you loose weight while taking hydroxyzine?
    Hydroxyzine has been my life saver but I have noticed a gradual increase in weight. My blood pressure has also gone up. I don't have the increased hunger but what scares me is I am not eating more than I normally do. I do not eat breakfast. I have a Glucerna at lunch and then dinner, protein potatoes/rice and veggies, sometimes pasta nothing huge and a snack at night. Maybe a small bowl of ice cream but not every night. I do not drink soda, lots of water and with dinner a large glass of apple juice. I have noticed every year I put on a little bit more weight. I was tested for my thyroid and it is normal. I haven't started an avid work out program. Doing high intense impact will not work due to my IC. I would like to try power walking. Anyone else experience any of these issues?

More questions for: Suboxone, Tramadol Hydrochloride

You may be interested at these reviews (Write a review):

  • Suboxone treatment may have caused my trichotillomania
    It's a long story of how I became addicted to opiates after 15+ years of chronic pain, but I decided to give up pain killers and try suboxone/subutex treatment. Shortly thereafter, I began pulling hair. First from my head, then when the bald spots became too obvious I started pulling from all over. It seemed to be triggered by stress or anxiety but not always. I did not make an association until recently, when I finally stopped the suboxone. It was two weeks of miserable withdrawal, much worse than from pain killers themselves, but I am finally out of the haze I'd be in all of that time, and I have no urge to pull hair whatsoever. I don't know how often the association of suboxone use and trichotillomania has been examined, but I wanted to share my experience in case anyone else is in a similar situation. Also, if you are considering starting suboxone treatment, don't. Withdrawal from opiates will lead to a few pretty rough days, but that's nothing compared to what you'll go through during suboxone withdrawal.
  • Pacemaker experience
    I had a pacemaker installed about 5 weeks ago. I went to the doctors because I was feeling fatigue, shortness of breath, I felt as if someone was holding my heart in their hand and I had some confusion and dizziness.

    To get to the point, after my first visit with my PCP I decided to go directly to emergency via 911 since my PCP was basically ignoring, or better put, had no sense of urgency regarding how I was feeling even though she knew my heart rate had dropped and was steady at 44 bpm, my normal rate 62 bpm.

    The night I was in observation at the hospital I dropped to 20 bpm, next day I had a pacemaker installed, had I not taken the initiative to call the hospital I don't know if I would have continued dropping until I was dead, I don't know enough about the science behind this to draw that conclusion but common sense tells me yes.

    I have explained this in another post but I cannot find it, not sure what I am doing wrong, so I am writing another post because I have more to add after a couple of weeks since my last post.

    The issue I have is I am still tired after more than a month after the installation of the pacemaker. I had the bpm (beats per minute) on my pacemaker increased from 60, the factory settings, to somewhere in the mid 60's.......so I thought. I went to the hospital twice to have my pacemaker "tweaked" but when I met with the cardiologist for my "one week" follow up, which took almost three weeks to see him due to his heavy schedule, he told me there were never any changes made to my pacemaker, I was still at 60 bpm. How could this be since I was told twice it had been increased? I had the wand on my chest and the nurse made the changes which were made due to my complaining about being exhausted still, the reason I went to the PCP in the first place five weeks ago.
    Was she playing mind games, thinking the power of suggestion would make me feel better? If so I am disgusted to think she would feel I was faking my feelings of exhaustion, what she did had absolutely no effect on how poorly I was feeling.

    To get to the point, I finally had my first meeting with the surgeon, he raised my bpm to 75 from 60, was going to go to 80 but changed his mind. The moment he made the change to 75 bpm from my original 60 he asked if I was feeling better, feeling better after 60 seconds of changing the bpm, how is that possible? I told him no, kind of too soon to tell. His reply was "it looks like we have done everything we can on our end, your heart was not significantly damaged, your pacemaker is working as it should, therefore there must be something else making you feel so poorly so I suggest you see an internal medicine specialist." My brain had a big WHAT sign flashing, I couldn't believe what he was saying, basically beat it and move on, I don't have the time to deal with you anymore. Lets see, the appointment lasted 25 minutes and he does not have the time to work with me anymore, sorry but that irritates the hell out of me.

    He was washing his hands of me, nothing else he could do so spend time and money finding out what the problem is with an internest, it is not my heart according to the cardiologist. The appointment ended and I left wondering how I was going to find out what is causing my issues.

    To my great fortune a nurse with 20 years experience teaching doctors and nurses how to use the pacemaker computer asked me to come into her office after my appointment with the cardiologist, she asked me this prior to seeing the doctor. Thank God she did as the doctor did not do a thorough job adjusting the pacemaker, she adjusted what the doctor had, tweaked the pacemaker a bit, had me walk for 10 minutes and come back to the office and did a bit more tweaking, I slowly started feeling a touch better. She asked me to come back in two weeks and she would see if the pacemaker needed to be tweaked a bit more. I was walking on air, still not close to my "normal", thrilled I was not just a number being tossed in the heap of unfixed people. I am feeling 70% better than how I felt prior to the doctor and her tweaking the pacemaker. Had she not been there that day and had the opportunity to do this I would be on a never ending search for what is making me feel so exhausted and!
    dizzy.

    There is a moral to this which I will let you draw your own conclusion. In my mind it is trust God will intervene, he certainly did when the nurse asked me to see her after the appointment with the surgeon. The reason I feel this way is because she was there and is only there on Fridays, the day I had my appointment. I never would have gone back again after my meeting with the doctor and I would have been spending needless hours and money looking through the wrong box for what ales me. Now it is obvious it was my pacemaker settings, my heart rate was set too low and the pacemaker was not fine tuned properly with the proper slope and other settings.

    Don't let these doctors do what mine tried doing with me, be aggressive and insist on more adjustments if you have issues similar to mine.

    AS I sit here I am still tired, I could easily take a nap but I am better than I was yesterday, significantly.

    Best of luck to all. Your comments will be very much appreciated.
  • Yawning after taking sub
    Within a few minutes after I take my Suboxone film I seem to get intense yawning event along with runny nose & watery eyes lasting 5-15 mins. Sometimes I can make it subside by drinking a lot of water if I am in a place I can get it. I have been on Sub for approx 5 yrs. & have only noticed this side effect during the past 1 yr or so. It doesn't seem to matter if I take 1/2 or a whole film, (4mg or 8mg.)
    While this isn't life shattering it can be quite annoying if I am out in public, at work, etc. The yawning gets so intense at times I feel like my jaw will unhinge & can't control it at all.
    It seems paradoxical to me. Previously taking Sub would stop any typical opiate withdrawal symptoms such a yawing & runny nose & eyes. Now it actually causes this effect. I don't get any other feelings of going into withdrawal. Just those I mentioned. Could it be a reaction to the naloxone?
  • No noticeable effects
    No noticeable effects when used together. Tramadol dose 50-100 mg's four times a day.
  • I wish i had never taken ambien
    Ambien was prescribed after my sleep study showed severe sleep latency and awakening. In the five hours I slept I woke 85 times and had only 5 minutes of deep sleep. However, the doctors couldn't make a recommendation because they could detect no cause for the poor sleep pattern. My doctor offered Ambien and since I had obviously needed the help sleeping I took it. For the next 10 years I suffered incredible depression. For example I remember laying in bed staring at the ceiling with tears rolling into my ears but I was too tired to wipe them away and realizing that I wanted to die so badly but there was no way I could have done anything about it. The worst effects were the loss of consciousness and the verbal abuse that I heaped on my husband and son. An example of each : I actually had sex with my husband that I could not remember amd hundreds of other actions and discussions. My husband started asking every morning what I remembered of the night before. He could usually tell when I was Ambien-awake (his name for it) he said my eyes would get glassy and my voice cadence would be off. Unfortunately my oldest son was going from infant to 8 years old at this time and any ifraction or even without provocation I would scream horrible things in his face. I don't remember much of it but what I do remember causes me enormous regret. He went from a happy and active toddler to a terrified amd anxious pre-teen. We are still working through the effects of this behavior. Finally, after a surprise pregnancy (see example above) My baby was placed in NICU and I stayed at the Ronald McDonald House and my son and husband visited when they could. Somehow my Ambien prescription was stopped and so I began going through withdrawal but I had no idea what was going on. My vision became so blurred thqt I couldn't identify items unless they were very large and then only by colors. When I visited my son those several days in the NICU I couldn't walk straight and would try to aim myself toward my goal until I hit a wall and I would correct course. These things didn't bother me at all but the nurses in the NICU were with me nearly the entire day because they were afraid I would have a stroke or who knew. Finally, after discussing these symptoms we decided to gradually stop the medication. Thankfully, i didn't have any withdrawal symptoms then. I did feel like an incredibly heavy and black blanket had been lifted away. Ever since I have had very little trouble with depression despite the continuation of sleep disturbance and pain. On a scale from one to 10 for depression with 10 being committing suicide I think my 10 years on the medicine was probably an 8.5 (I desperately wanted to die) and since stopping the medication I don't think it has gone above a 4 and is usually a 2 or 3. I will spend the rest of my life trying to repair the damage my verbal abuse caused my oldest son and my husband. For 10 years they lived in fear of my rages if I had a bad episode with Ambien.

More reviews for: Suboxone, Tramadol Hydrochloride

Comments from related studies:

  • From this study (7 months ago):

  • Can I take suboxone after using tramadol

    Reply

  • From this study (2 years ago):

  • Just started suboxone yesterday for pain management. About an hour after I took it yesterday I did experience some sweating and nausea. Today however, it caused me to vomit lunch. I went and ate dinner an hour or two later and took a naproxen for a developing migrane. About an hour after taking the naproxen I began vomiting again, once the bulk of dinner was done coming up, I began throwing up blood. Is this because of the suboxone?

    Reply

    MJ on Apr, 12, 2013:

    It very well could be from the Suboxone. I have been on it for the last 6 years. The first 3 were hell. I would vomit several times evry day along with severe abdominal pain. I was taking 32mg a day..high dose..went down to just 12mg a day and problem went away. Best advise is to taper off slowly and try to get off it completly.

    Reply

    shannon on Apr, 13, 2013:

    About suboxone...it is a tagonist/antagonist drug, therefore, can cause some rather abrupt withdrawl type effects and the issues you describe can be one of many symptoms you would have if you were NOT taking the suboxone. It works to give narcotic management yet deter overuse by having the drug Naloxone, the same med we carry on the ambulance to reverse narcotics, in it. Too much or even very little of the narcan part of the drug will cause immediate withdrawl type symptoms that can include severe nausea and vomiting, sweats, chills, diarrhea, headaches and many other symptoms. Talk to your prescriber and see what they say is my advice.

    Reply

Complete drug side effects:

On eHealthMe, Tramadol Hydrochloride (tramadol hydrochloride) is often used to treat pain. Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat opiate withdrawal. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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