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Home > Tramadol > Suboxone > Tramadol and Suboxone

Review: Tramadol and Suboxone

This review analyzes the effectiveness and drug interactions between Tramadol and Suboxone. It is created by eHealthMe based on reports of 52 people who take the same drugs from FDA and social media, and is updated regularly.

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What are the drugs

Tramadol hydrochloride (what 6,862 Tramadol Hydrochloride users reported?) has active ingredients of tramadol hydrochloride. It is used in pain.

Suboxone (what 8,240 Suboxone users reported?) has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is used in opiate withdrawal.

On Sep, 12, 2014: 52 people who take Tramadol Hydrochloride, Suboxone are studied

Tramadol Hydrochloride, Suboxone outcomes

Drug combinations in study:
- Tramadol Hydrochloride (tramadol hydrochloride)
- Suboxone (buprenorphine hydrochloride; naloxone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol Hydrochloride is effectiven/a0.00%
(0 of 1 people)
n/a0.00%
(0 of 1 people)
33.33%
(1 of 3 people)
n/an/an/a
Suboxone is effective50.00%
(1 of 2 people)
100.00%
(1 of 1 people)
n/a100.00%
(3 of 3 people)
n/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
SomnolenceWithdrawal SyndromeDrug Exposure During PregnancySeizuresn/an/an/aFall
Psychomotor HyperactivityHallucinationGrand Mal ConvulsionSyncope
Feeling JitteryPainAnaemia
DeathPulmonary OedemaPain
Feeling AbnormalMigraineWeight Decreased
Hepatic SteatosisOverdoseSpinal Osteoarthritis
ObesitySeizuresVomiting
Cardiac HypertrophyRapid Heart BeatGastritis
Renal ArteriosclerosisConfusionConfusional State
Rapid Heart BeatVomitingAsthenia

Drug effectiveness by gender :

FemaleMale
Tramadol Hydrochloride is effective25.00%
(1 of 4 people)
0.00%
(0 of 1 people)
Suboxone is effective80.00%
(4 of 5 people)
100.00%
(1 of 1 people)

Most common drug interactions by gender * :

FemaleMale
ConvulsionFall
Loss Of ConsciousnessSinusitis
SomnolencePulmonary Embolism
PainOesophagitis
Multiple Drug OverdoseAsthenia
HeadacheAtrial Fibrillation
Drug AbuseVomiting
FallCerebrovascular Accident
NauseaPancytopenia
Oedema PeripheralLoose Tooth

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tramadol Hydrochloride is effectiven/an/an/a25.00%
(1 of 4 people)
0.00%
(0 of 1 people)
n/an/an/a
Suboxone is effectiven/an/an/a100.00%
(3 of 3 people)
100.00%
(2 of 2 people)
0.00%
(0 of 4 people)
n/an/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/an/aDrug ToxicityGrand Mal ConvulsionConvulsionPulmonary OedemaDrug IneffectiveDecreased Appetite
Drug Screen PositiveDrug Exposure During PregnancyLoss Of ConsciousnessWithdrawal SyndromeDrug Withdrawal SyndromeCataract
Accidental OverdoseOverdoseHeadachePainVomitingOrthostatic Hypotension
MigraineDrug AbuseHallucinationPain In ExtremityGastritis
VomitingMultiple Drug OverdoseAgitationGastrointestinal DisorderSpinal Osteoarthritis
SeizuresDrug DependenceDrug ToxicityBack PainSupraventricular Extrasystoles
SomnolenceCompleted SuicideDelusional PerceptionLoose Tooth
DyskinesiaDepressionFallAsthenia
Head InjuryDrug Withdrawal SyndromePainAtrial Fibrillation
LethargyPulmonary CongestionBalance DisorderCerebrovascular Accident

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tramadol and Suboxone?

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- group for people who take Tramadol and Suboxone
- group for people who take Suboxone
- group for people who take Tramadol Hydrochloride

Comments from related studies:

  • From this study (4 months ago):

  • Can I take suboxone after using tramadol

    Reply

  • From this study (1 year ago):

  • Just started suboxone yesterday for pain management. About an hour after I took it yesterday I did experience some sweating and nausea. Today however, it caused me to vomit lunch. I went and ate dinner an hour or two later and took a naproxen for a developing migrane. About an hour after taking the naproxen I began vomiting again, once the bulk of dinner was done coming up, I began throwing up blood. Is this because of the suboxone?

    Reply

    MJ on Apr, 12, 2013:

    It very well could be from the Suboxone. I have been on it for the last 6 years. The first 3 were hell. I would vomit several times evry day along with severe abdominal pain. I was taking 32mg a day..high dose..went down to just 12mg a day and problem went away. Best advise is to taper off slowly and try to get off it completly.

    Reply

    shannon on Apr, 13, 2013:

    About suboxone...it is a tagonist/antagonist drug, therefore, can cause some rather abrupt withdrawl type effects and the issues you describe can be one of many symptoms you would have if you were NOT taking the suboxone. It works to give narcotic management yet deter overuse by having the drug Naloxone, the same med we carry on the ambulance to reverse narcotics, in it. Too much or even very little of the narcan part of the drug will cause immediate withdrawl type symptoms that can include severe nausea and vomiting, sweats, chills, diarrhea, headaches and many other symptoms. Talk to your prescriber and see what they say is my advice.

    Reply

    Snoods on May, 1, 2013:

    I am a 54 year old pysch nurse that uses suboxone in my practice. I think there is confusion regarding the naloxone(Narcan) included in this drug. The Narcan has little to no effect unless you try to inject suboxone. The Narcan is not the main opiate blocker, as it is metabolized by the liver almost immediately. Suboxone is a "mu" agonist (stimulator) and a kappa antagonist (blocker). That is why you get pain relief without much intoxication. Paramedics tend to focus on the 20 or so drugs they carry on an ambulance and do not have the broad knowledge of a complex drug like suboxone.

    Reply

    Snood on May, 1, 2013:

    Sweating, nausea, vomiting, and headache are all signs of opiate use. Suboxone is a powerful opiate, although it may not feel like one. You will slowly adapt to these symptoms, and faster if you decrease you dose

    Reply

    MJ on May, 2, 2013:

    "Sweating, nausea, vomiting, and headache are all signs of opiate use" Suboxone is a very confusing drug..My old Dr thought I wasn't getting enough and was going thru withdrawal, so he raised my dose to 32mg.big mistake, but even at only 8mg I feel like I have the flu, now that's withdrawal. I hate this drug because most dr's don't kno jack about it and are destroying peoples lives from it. I haven't been the same since it, and not from abuse. I just can't find the happy medium dose I need to just feel normal again. Any help will help.

    Reply

    MJ on May, 2, 2013:

    Yes it is.I had the same problem. How much are you taking? How long has it been since you had an opiate? You can't mix the two..EVER. You need about a two day (min.) window between the two. It sounds like your body is having a hard time with such a strong drug. Suboxone is VERY strong and lasts VERY long so it is very hard to know if you had too much until it is to late. Try not taking any more until your symptoms go away..then take a little bit and wait for at least an hour and repeat until better. NOTE..I do not know your dosage so please do not take more than your dose..EVER...but try to lower it if able.

    Reply

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Complete drug side effects:

On eHealthMe, Tramadol Hydrochloride (tramadol hydrochloride) is often used to treat pain. Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) is often used to treat opiate withdrawal. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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