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Review: Tramadol and Wellbutrin





Summary: drug interactions are reported among people who take Tramadol and Wellbutrin together.

This review analyzes the effectiveness and drug interactions between Tramadol and Wellbutrin. It is created by eHealthMe based on reports of 1,636 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Tramadol and Wellbutrin >>>

What are the drugs

Tramadol hydrochloride has active ingredients of tramadol hydrochloride. It is often used in pain. (latest outcomes from Tramadol hydrochloride 6,864 users)

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (view latest outcomes from 54,972 users)

On Nov, 28, 2014: 1,636 people who take Tramadol Hydrochloride, Wellbutrin are studied

Tramadol Hydrochloride, Wellbutrin outcomes

Drug combinations in study:
- Tramadol Hydrochloride (tramadol hydrochloride)
- Wellbutrin (bupropion hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Tramadol Hydrochloride is effective24.00%
(6 of 25 people)
16.67%
(5 of 30 people)
26.67%
(4 of 15 people)
30.00%
(9 of 30 people)
30.00%
(6 of 20 people)
42.86%
(6 of 14 people)
33.33%
(1 of 3 people)
n/a
Wellbutrin is effective30.00%
(3 of 10 people)
31.82%
(7 of 22 people)
20.00%
(4 of 20 people)
32.00%
(8 of 25 people)
38.24%
(13 of 34 people)
47.62%
(10 of 21 people)
30.00%
(3 of 10 people)
100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaPainConvulsionDeep Vein ThrombosisAnxietyDepressionExhaustion, Fatigue, Lethargy, Tiredness, WearinessPain
Drug Toxicity NosAnxietyPyrexiaConvulsionDepressionAnxietyMigraine Without AuraAnxiety
Lobar Pneumonia NosEmotional DistressVomitingFatigueChest PainSuicidal IdeationShort-term Memory LossNausea
AnxietyConvulsionPancreatitisExhaustion, Fatigue, Lethargy, Tiredness, WearinessMyocardial InfarctionSuicide AttemptFacial EdemaFall
ConvulsionCholecystitis ChronicNauseaInsomniaPainLoss Of ConsciousnessGrand Mal ConvulsionFatigue
Grand Mal ConvulsionGrand Mal ConvulsionAbdominal Pain UpperSleep DisorderEmotional DistressAggressionConfusional StateDepression
Cardiac ArrestAbdominal PainAstheniaHydrochloride - ThioridazineArthritisAngerMemory ImpairmentBack Pain
ObesityNauseaCholecystitisBlood Cortisol DecreasedPain In ExtremityHallucination, AuditorySweating - ExcessiveDyspnoea
Feeling AbnormalDrug HypersensitivityCholelithiasisBlood Cortisol IncreasedLoss Of ConsciousnessPalpitationsHeart PoundingHeadache
PainCyanosisPainBlood Cortisol AbnormalAstheniaExhaustion, Fatigue, Lethargy, Tiredness, WearinessDry MouthConstipation

Drug effectiveness by gender :

FemaleMale
Tramadol Hydrochloride is effective29.91%
(32 of 107 people)
17.24%
(5 of 29 people)
Wellbutrin is effective32.14%
(36 of 112 people)
41.94%
(13 of 31 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
AnxietyBack Pain
NauseaDepression
FallFatigue
FatigueFall
DepressionAnxiety
DiarrhoeaNausea
HeadacheDyspnoea
DyspnoeaChest Pain
ConstipationHeadache

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Tramadol Hydrochloride is effective0.00%
(0 of 1 people)
n/a25.00%
(1 of 4 people)
23.08%
(3 of 13 people)
20.00%
(13 of 65 people)
16.42%
(11 of 67 people)
8.82%
(3 of 34 people)
31.58%
(6 of 19 people)
Wellbutrin is effective100.00%
(1 of 1 people)
n/a33.33%
(1 of 3 people)
33.33%
(4 of 12 people)
17.46%
(11 of 63 people)
21.33%
(16 of 75 people)
33.33%
(11 of 33 people)
22.73%
(5 of 22 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Diabetes MellitusUpper Respiratory Tract InfectionCompleted SuicideNauseaDiabetes MellitusPainAnxietyFall
White Blood Cell Count DecreasedCardio-respiratory ArrestTorsade De PointesAnxietyFallPainFatigue
Hallucination, AuditoryCardiac ArrestCardiac ArrestCompleted SuicideAnxietyFallNausea
RhinorrhoeaVomitingGallbladder DisorderBack PainBack PainDiarrhoeaWeight Decreased
Heart Rate IncreasedNauseaVentricular FibrillationType 2 Diabetes MellitusDepressionNauseaPain
Blood Pressure DecreasedRespiratory ArrestCholelithiasisConvulsionNauseaEmotional DistressDepression
Accidental ExposureAbdominal PainComaNauseaDyspnoeaFatigueHypertension
Cholecystitis ChronicHeadachePanic AttackArthralgiaAnaemiaAnxiety
PancreatitisPainHypertensionConstipationPyrexiaDizziness
CholelithiasisAbdominal Pain UpperDiabetic NeuropathyFatigueCoughDyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Tramadol and Wellbutrin?

You are not alone! Join a related mobile support group:
- support group for people who take Tramadol and Wellbutrin
- support group for people who take Tramadol Hydrochloride
- support group for people who take Wellbutrin

Can you answer these questions (Ask a question):

  • In having a-fib, can one use xarelto along with temador for brain tumor treatment
    Both drugs lower platelets, is using Xarelto unwise
  • Can i take diclofenac sodium mispoprostol with tramadol hcl?
    I have bad arthritis in my hips - very painful and affecting my quality of life. My doctor like to prescribe pills. He has given me Diclofenac Sodium Mispoprostal and Tramadol HCL. I have experienced minimal side effects i.e.: drowsiness but thats about it. I just want to be sure that I can take these drugs together.
  • I am on 2 x daily rifampin and 4 x daily cephalixin 500mg and and awake exhausted after 8-9 hours sleep and the fatigue is unbelievable all day every day, is this "normal" or should i investigate ore (1 answer)
    Had total knee replacement 11/12, bad from the start, knee swollen/hot/painful/unstable for most of 2 years before a mechanically successful Revision that found a loose patella and both ends of the prostheses loose. In spite of 10-12 aspirations and almost as many samples sent to labs for testing the result was always "no growth after a week". Following the revision, 10 days after, surgeons office called and says yes you have a staph E infection. Immediate therapy with 6 weeks of 3 X day IV PLUS 2 x per day oral Rifampin.
    IV over but now on the 2 X day Rifampin PLUS 4 X day 500mg cephalexin and the fatigue is unbelievable. Wake up exhausted after 8 hours sleep, daily hour plus mid afternoon naps.
  • Is it safe to take demerol while taking tramadol hydrochloride and hydroxychloroquine (2 answers)
    I am experiencing acute, debilitating pain due to the Chikungunya virus, which has reintroduced all of the previous painful symptoms I have,ongoing and in the past, from Fibromyalgia, Arthritis, tendonitis and severe headaches. It's in its 38th day and I am basically crippled from neck to feet. Have to sleep propped up as arms throb with pain when horizontal. The only thing that has subdued the pain slightly are Oxycocet and Ibuprofen, but the pain never goes away. My hands and feet are so inflammed it's difficult to perform even the smallest tasks of personal hygiene and housekeeping. I have difficulty controlling my bladder and often don't make it to the washroom in time. Just started on Demerol today so will no longer take the Oxycocet, but am concerned of the interactions with Demerol, Hydroxychloroquine and Tramadol Hydrochloride extended release tablets that I take daily for the Fibromyalgia and Arthritis. I have dealt with a great deal of pain through the years, but I now have the pain of every serious illness I have had in my lifetime, all at the same time. I honestly didn't think a person could deal with this much pain at once. I have tried and am still taking several vitamins and herbal supplements as well as drinking tons of water and eating really well. Lots of berries, dark vegetables, apples, yogurt and minimal meat. Taking turmeric, papaya leaf, ginger, cinnamon and boswellia for the inflammation. Taking minimal wheat products, sugar and no alcohol. Also, drinking green, fennel and nettle tea daily. I know this is a lot of information, but I really need help and wonder if anyone has any suggestions! Thanking you in advance!!!
  • Does anyone experience heart palpitations causedby their acid reflux ?
    I have had acid reflux/Gerd for 4 years + Was not believed that symptoms were real for a while as had no heartburn and a diagnosis of Fibromyalgia which even now some medics think is imaginary...it's NOT!!! Following a demeester score of 45 ( very high confirmation of acid reflux) and discovery of a large hiatal hernia, ( a classic physical cause of acid reflux) I had hernia repair operation and LINX anti reflux surgery. Throughout the four years a major symptom of my acid reflux were heart palpatations. They started at the same time I started with reflux and cleared up after the surgery. I have been reflux free palpitation free and antacid free for four months. then I was put on Gabapentin for back spasm and the reflux returned along with the palpitations. Medics keep insisting this is just anxiety yet eat a food that gives me reflux also starts the palps which is the indicator of the reflux as I do not have heartburn. Comes on when relaxing and eating watching tv ( no anxiety present) and when I am sleeping peacefully ( no anxiety present) my heart wakes me up and fires off into tachycardia. Recently a doctor has said it is now known that acid reflux irritates the nerves in the solar plexus area and that triggers the palps. Anyone else experienced this? Are there any studies on it at all? Thanks all.

More questions for: Tramadol Hydrochloride, Wellbutrin

You may be interested at these reviews (Write a review):

  • Intrsoccular pressure increase associated with wellbutrin
    I was given a prescription for Wellbutrin in approximately 1998. I had has my ocular pressure checked a year prior to this and it was okay. At the time, I only needed to wear reading glasses, common in people over 45. I took the drug at the full prescribed dosage for two weeks. Immediately prior to the narrow angle glaucoma episode, my vision had actually seemed to improve. For one day, prior, I could read without reading glasses. The following night, I was watching tv, and things suddenly became foggy. It was actually as if a fog had enveloped the room. I could not see anything except to discern between light and dark areas. I had to have emergency laser surgery the next morning. I mentioned to the doctor that Iwas taking Wellbutrin to stop smoking, and asked if it could have caused the ocular pressure increase. he consulted the PDR, and said there was no mention of it causing increases in ocular pressure. One year later my primary care doctor again insisted that I stop smoking, and again I mentioned that I thought it might increase ocular pressure. She told me to take a half dose, I did, and I took it one week, at which time I again experienced another episode of narrow angle glaucoma. When I go to the doctor's office my pressure in my left eye was 72, and 68 in my right eye. I was then referred on a triage basis to another doctor. I spent the rest of the day in his office having drops administered every fifteen minutes(extremely painful). I had extensive laser surgery the next morning.It required over fifty shots from the laser machine into each eye, (also extremely painful). I had lost considerable peripheral AND CENTRAL VISION in my left eye, and a good deal in my right. As a result of having to have such extensive laser surgery I also had cataracts that began at 50% maturity. I was advised by the surgeon that I should wait to have the cataracts removed "until my vision and quality of life was so poor that I was ready to commit suicide" because having the cataracts removed would cause the pressure in my eyes to become very difficult to control, and that more than likely I would end up being black blind. I would never use Wellbutrin under any circumstances, and I always check to make sure that any new meds I may be put on don't have anything to do with an increase in ocular pressure. If they do, I refuse to take them. The surgeon said he was surprised that I didn't lose more vision than I did, and I am grateful that I didn't, and that he was a good surgen. He wrote an article concerning this case for a medical journal since he said he had been seeing a recent increase of narrow angle glaucoma.
  • Librium 25mg and wellbutrin 300mg for >1 month
    I've been taking librium twice daily, morning and night, for about 3 months now along with wellbutrin XL in the morning. I've basically had the mood of "I don't care" and a great boost in confidence.
  • Bedwetting with paxil and wellbutrin
    I have been using both of these drugs and now have bedwetting issues 5 times a week on average. I would rate the bedwetting as moderate about a6/10 but my wife and I can live with this as she had made the comment " you are back to the man I married ". I started taking these due to depression about work and anxiety about work. We both think we can live with the bedwetting as no one needs to know about it
  • Wellbutrin caused my trigeminal neurlagia
    So I'm writing this to hopefully shed light to other users in the same position I was in. I had taken Wellbutrin for about 4 years. The pain experienced in my face was excruciatingly painful. It was just on one side of my face between my temple and upper lip. All the symptoms reflected Trigeminal Neuralgia. But even with an MRI nothing could be found. I suffered for 3 of those years with pain coming and going, not understanding what was going on. Finally one day I decided hell with Wellbutrin and just stopped taking it. It's been 6 months now and I have yet to have a single shred of pain. Coincidence? I doubt it.
  • Lorazepam nearly killed me during cancer treatment
    Day 31 of cold turkey and I want to die. It is a roller coaster from body tics and sweats to rage and crying in one day. I felt so good the 4h day of c/t. It was like before my cancer diagnosis. My bowels are better off Lorazepam. I threw up during bowel movements from the pain. Off Lorazepam first normal bowel movement in over 2 years. Stomach so damaged by Lorazepam that I have absolutely no appetite. I force myself to eat. Neuropathy in hands nearly gone. Feet are better but slower. Lymphedema that appeared after one year on Lorazepam is now gone. I have full range of motion.

More reviews for: Tramadol Hydrochloride, Wellbutrin

Comments from related studies:

  • From this study (4 months ago):

  • pain and heaviness in arms and legs, comes and goes. relieved by heat but gets worse immediately once heat is removed.

    Reply

  • From this study (10 months ago):

  • depression, anxiety, adhd, L4-5 black disc with impingement

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  • From this study (11 months ago):

  • Do not take all drugs listed at same time. Am on "pulse therapy" with antimacrobials. Do not take coq10 when on Mepron/malarone. Take Florastor probiotic 2x's a day to fight c.diff & other probiotics. Also take FiberSmart, DigestSmart, & slippery elm, marshmallow root for GI regularity. Drink at least 4 cups green tea daily. CDC confirmed lyme positive in 2010 (September), was bit in May of same year. Had psychiatric & cognitive dysfunction immediately following rash. Further testing show active infection in brain - neuro-lyme dx'd.

    Reply

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Complete drug side effects:

On eHealthMe, Tramadol Hydrochloride (tramadol hydrochloride) is often used to treat pain. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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