Review: taking Trileptal and Clonazepam together
Summary: drug interactions are reported among people who take Trileptal and Clonazepam together.
This review analyzes the effectiveness and drug interactions between Trileptal and Clonazepam. It is created by eHealthMe based on reports of 1,204 people who take the same drugs from FDA and social media, and is updated regularly.
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Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. (latest outcomes from 11,895 Trileptal users) Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from 41,341 Clonazepam users)
What are the drugs
Trileptal has active ingredients of oxcarbazepine. It is often used in bipolar disorder. (latest outcomes from 11,895 Trileptal users)
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from 41,341 Clonazepam users)
On Mar, 1, 2015: 1,204 people who take Trileptal, Clonazepam are studied
Drug combinations in study:
- Trileptal (oxcarbazepine)
- Clonazepam (clonazepam)
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Trileptal is effective||28.57%|
(2 of 7 people)
(4 of 6 people)
(2 of 5 people)
(2 of 14 people)
(3 of 11 people)
(4 of 5 people)
(3 of 5 people)
(0 of 1 people)
|Clonazepam is effective||33.33%|
(1 of 3 people)
(3 of 6 people)
(4 of 7 people)
(5 of 14 people)
(12 of 17 people)
(3 of 5 people)
(4 of 4 people)
Drug effectiveness by gender :
|Trileptal is effective||41.03%|
(16 of 39 people)
(4 of 15 people)
|Clonazepam is effective||63.41%|
(26 of 41 people)
(6 of 15 people)
Drug effectiveness by age :
|Trileptal is effective||n/a||16.67%|
(1 of 6 people)
(0 of 3 people)
(2 of 15 people)
(5 of 16 people)
(6 of 15 people)
(6 of 32 people)
(0 of 1 people)
|Clonazepam is effective||n/a||16.67%|
(1 of 6 people)
(1 of 3 people)
(4 of 15 people)
(7 of 17 people)
(9 of 17 people)
(9 of 31 people)
(1 of 2 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Hyponatraemia||Convulsion||White Blood Cell Count Decreased||Weight Increased||Weight Increased||Mental Status Changes||Sleep Disorder Due To General Medical Condition, Insomnia Type||Weight Increased|
|Tremor||Vision Blurred||Blood Sodium Decreased||Diabetes Mellitus Inadequate Control||Suicide Attempt||Lipoatrophy||Panic Attack||Diabetes Mellitus|
|Confusional State||Confusional State||Fatigue||Diabetic Eye Disease||Loss Of Consciousness||Convulsion||Anxiety Disorder||Convulsion|
|Headache||Angioneurotic Oedema||Loss Of Consciousness||Type 2 Diabetes Mellitus||Hypoaesthesia||Seizures||Osteopenia||Depression|
|Epilepsy||Headache||Anxiety||Blood Glucose Increased||Nasal Congestion||Oesophageal Spasm||Depression||Dizziness|
|Adrenal Carcinoma||Palpitations||Mean Cell Haemoglobin Increased||Proteinuria||Lethargy||Hypersexuality||Sleepiness||Headache|
|Mania||Inappropriate Antidiuretic Hormone Secretion||Red Blood Cell Count Decreased||Diabetic Retinopathy||Hyperhidrosis||Sleep Disorder Due To General Medical Condition, Insomnia Type||Type 2 Diabetes Mellitus|
|Rash Erythematous||Syncope||Monocyte Count Increased||Diabetic Neuropathy||Osteoporosis||Panic Attack||Vomiting|
|Asthenia||Systemic Lupus Erythematosus||Intentional Overdose||Diabetes With Hyperosmolarity||Rheumatoid Arthritis||Anxiety Disorder||Drug Ineffective|
Most common drug interactions by gender * :
|Weight Increased||Diabetes Mellitus|
|Diabetes Mellitus||Type 2 Diabetes Mellitus|
|Drug Ineffective||Weight Increased|
Most common drug interactions by age * :
|Pancreatitis||Convulsion||Weight Increased||Headache||Completed Suicide||Diabetes Mellitus||Weight Increased||Fall|
|Bradycardia||Dehydration||Convulsion||Dizziness||Weight Increased||Type 2 Diabetes Mellitus||Headache||Dizziness|
|Apnoea||Hyperpyrexia||Status Epilepticus||Suicidal Ideation||Type 2 Diabetes Mellitus||Nausea||Diabetes Mellitus||Anxiety|
|Decreased Activity||Bronchopneumonia||Suicidal Ideation||Diabetes Mellitus||Depression||Weight Increased||Dizziness||Drug Ineffective|
|Neonatal Respiratory Distress Syndrome||Cardiac Failure||Depression||Confusional State||Diabetes Mellitus||Diabetes Mellitus Inadequate Control||Type 2 Diabetes Mellitus||Thrombocytopenia|
|Drug Exposure During Pregnancy||Death||Drug Ineffective||Vision Blurred||Vomiting||Hyponatraemia||Depression||Pain|
|Hypotonia||Dental Caries||Diabetes Mellitus||Back Pain||Diabetes Mellitus Inadequate Control||Headache||Nausea||Ataxia|
|Weight Increased||Elevated Mood||Anger||Paranoia||Nausea||Neuropathy Peripheral||Vomiting||Osteoarthritis|
|Nephrolithiasis||Appetite Decreased||Somnolence||Dyspnoea||Suicide Attempt||Insomnia||Pain||Anaemia|
|Gastritis||Blood Carbon Dioxide Abnormal||Aggression||Anger||Cardiac Arrest||Dizziness||Completed Suicide||Pruritus|
* Some reports may have incomplete information.
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Can you answer these questions (Ask a question):
- Galatamine or buspirone for awake bruxism
patient diagnosed with alzheimers since 2004.she recently developed the awake bruxism. I just began giving her 10 mg of buspirone. it appears to be somewhat effective but not quite as I expected. from reading I've seen that galatamine helps.
- I have heard that taking clonazepam and diltiazem can cause bronchitis anyone have this reaction
I have bronchitis at least once a year, excess mucus and throat clearing. Tightening of the airways, mostly at night.was wondering if drug interactions could be the cause.
- Does clonazapam cause tinnitus or ringing in the ears? (1 answer)
Patient fell a year ago and injured her neck and broke a bone in her arm. Has had severe pain in her neck. Getting acupuncture frequently. Recently tried to change medication from Valium to Clonazepam, and developed severe tinnitus. She said she only missed two days of Valium. She also says she has skipped days without taking valium and never had a problem. She says Clonazepam caused the tinnitus. I can't find anything that states a side effect of clonazepam is tinnitus.
- Can you stop trileptal cold turkey?
I ran outta my Trileptal, the last time I took it was in the hospital on Saturday I was there for 2 days and I was normally taking 300mg 2x daily and the hospital gave me 600mg 4x on Saturday and the day before I took the one 300mg I had left in the morning. Since the hospital I have not had any Trileptal to be able to take because they didn't send me home with any because I'm from another State and I'm not sure if that's why but I should have my medicine tomorrow but I feel horrible and I just wanna know if physically I will be alright? Thank you so much and would appreciate a quick responce.
- I take klonopin and diltiazem (calcium channel blocker blood pressure medicine) and am concerned about side effects. my accupuncturist recommends the ashwagandha. anyone have any issues with this?
I take these prescription medications but have been going to an accupuncturist since 2012. I have trouble sleeping at night without my clonazepam and take naps during the day and am having trouble losing weight. She thinks that my adrenal glands may be fatigued and told me to try something called Adrenal Response which contains Sensoril Ashwagandha. When I looked up Ashwaganda it said that it could interact with the Clonazepam or Klonopin and also with High blood pressure medication. I am a little concerned. I mentioned this to her and she said they both are metabolized by the liver and it should be ok to take it, just to take it an hour or more after I take the Clonazepam. Has anyone had any issues with interactions with their prescribed meds while taking Ashwagandha? I don't want to have to monitor my blood pressure because my blood pressure medication works good for me. Any help would be appreciated because I want to try it but I am a little scared too. Thanks, Crystal
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- A life of depression and fatigue (1 response)
1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
- 3 strong drugs together against neuropathic pain
Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.
The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.
The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.
It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.
There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.
Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.
The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).
Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.
I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
- Had nms in 2005, will trileptal increase chance of recurrence?
In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
- Could trileptal cause benign intracranial hypertension
My Daughter is 9 and was on Trileptal for three years and just started to have severe headaches that lasted for two weeks and were quickly and poorly diagnosed as a status migraine. Another week of pain and incorrect treatments finally led to more tests and the correct diagnosis of IIH. Supposedly the most susceptible person (1 in 5,000) to get IIH in the US is an over weight female in her 20's. Based on my daughters information and the information on this site, Female Trileptal patients appear to have a 1 in 1500 chance of IIH and if you are female and also aged 2 to 9, your chances are about 1 in 250. Or 20 times more susceptible than heavy, adult females.
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Constantly flapping hands, rocking while sitting
I have been experiencing hair loss in clumps while running fingers through my hair and i have blurred vision. The hair loss is recent..within the last week..the newest medicine is the pantoprazole
Heartrace & elevated Blood Pressure come & go. Short shallow breathing,restlessness,some unknown agitation, & restlessness started when I started Paxil. These symptoms. come & go frequently ,& now after the Trileptin was started 3 days ago , my chest. has been hurting with increased. exercise & nigh sweats started while breathing issues & restlessness have increased. t to the point of not enough sleep . My bowels have been salty smelling. since new years eve due to an overdose on Tylenol extra strength & Klonopin ,which the ER gave me charcoal for,discharging me when the liver levels were okay
Complete drug side effects:
On eHealthMe, Trileptal (oxcarbazepine) is often used to treat bipolar disorder. Clonazepam (clonazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Trileptal is used in:
- Clonazepam is used in:
Other drugs that are used to treat the same conditions:
- Trileptal alternatives:
- Clonazepam alternatives:
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
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