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Review: Trileptal and Clonazepam





Summary: drug interactions are reported among people who take Trileptal and Clonazepam together.

This review analyzes the effectiveness and drug interactions between Trileptal and Clonazepam. It is created by eHealthMe based on reports of 1,203 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Trileptal and Clonazepam >>>

What are the drugs

Trileptal has active ingredients of oxcarbazepine. It is often used in epilepsy. (latest outcomes from Trileptal 11,884 users)

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Clonazepam 41,274 users)

On Nov, 25, 2014: 1,203 people who take Trileptal, Clonazepam are studied

Trileptal, Clonazepam outcomes

Drug combinations in study:
- Trileptal (oxcarbazepine)
- Clonazepam (clonazepam)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Trileptal is effective28.57%
(2 of 7 people)
66.67%
(4 of 6 people)
40.00%
(2 of 5 people)
14.29%
(2 of 14 people)
27.27%
(3 of 11 people)
80.00%
(4 of 5 people)
60.00%
(3 of 5 people)
0.00%
(0 of 1 people)
Clonazepam is effective33.33%
(1 of 3 people)
50.00%
(3 of 6 people)
57.14%
(4 of 7 people)
35.71%
(5 of 14 people)
70.59%
(12 of 17 people)
60.00%
(3 of 5 people)
100.00%
(4 of 4 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
HyponatraemiaConvulsionWhite Blood Cell Count DecreasedWeight IncreasedWeight IncreasedMental Status ChangesSleep Disorder Due To General Medical Condition, Insomnia TypeWeight Increased
TremorVision BlurredBlood Sodium DecreasedDiabetes Mellitus Inadequate ControlSuicide AttemptLipoatrophyPanic AttackDiabetes Mellitus
Confusional StateConfusional StateFatigueDiabetic Eye DiseaseLoss Of ConsciousnessConvulsionAnxiety DisorderConvulsion
HeadacheAngioneurotic OedemaLoss Of ConsciousnessType 2 Diabetes MellitusHypoaesthesiaSeizuresOsteopeniaDepression
FatigueHyponatraemiaIrritabilityDyslipidaemiaOedema PeripheralDystoniaHypomagnesemiaNausea
EpilepsyHeadacheAnxietyBlood Glucose IncreasedNasal CongestionOesophageal SpasmDepressionDizziness
Adrenal CarcinomaPalpitationsMean Cell Haemoglobin IncreasedProteinuriaLethargyHypersexualitySleepinessHeadache
ManiaInappropriate Antidiuretic Hormone SecretionRed Blood Cell Count DecreasedDiabetic RetinopathyHyperhidrosisSleep Disorder Due To General Medical Condition, Insomnia TypeType 2 Diabetes Mellitus
Rash ErythematousSyncopeMonocyte Count IncreasedDiabetic NeuropathyOsteoporosisPanic AttackVomiting
AstheniaSystemic Lupus ErythematosusIntentional OverdoseDiabetes With HyperosmolarityRheumatoid ArthritisAnxiety DisorderDrug Ineffective

Drug effectiveness by gender :

FemaleMale
Trileptal is effective41.03%
(16 of 39 people)
26.67%
(4 of 15 people)
Clonazepam is effective63.41%
(26 of 41 people)
40.00%
(6 of 15 people)

Most common drug interactions by gender * :

FemaleMale
Weight IncreasedDiabetes Mellitus
Diabetes MellitusType 2 Diabetes Mellitus
HeadacheNausea
ConvulsionConvulsion
DepressionVomiting
DizzinessDizziness
NauseaDepression
Suicidal IdeationSomnolence
FatigueNeuropathy Peripheral
Drug IneffectiveWeight Increased

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Trileptal is effectiven/a16.67%
(1 of 6 people)
0.00%
(0 of 3 people)
13.33%
(2 of 15 people)
31.25%
(5 of 16 people)
40.00%
(6 of 15 people)
18.75%
(6 of 32 people)
0.00%
(0 of 1 people)
Clonazepam is effectiven/a16.67%
(1 of 6 people)
33.33%
(1 of 3 people)
26.67%
(4 of 15 people)
41.18%
(7 of 17 people)
52.94%
(9 of 17 people)
29.03%
(9 of 31 people)
50.00%
(1 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
PancreatitisConvulsionWeight IncreasedHeadacheCompleted SuicideDiabetes MellitusWeight IncreasedFall
BradycardiaDehydrationConvulsionDizzinessWeight IncreasedType 2 Diabetes MellitusHeadacheDizziness
ApnoeaHyperpyrexiaStatus EpilepticusDiabetes MellitusType 2 Diabetes MellitusNauseaDiabetes MellitusAnxiety
Decreased ActivityBronchopneumoniaSuicidal IdeationSuicidal IdeationDepressionWeight IncreasedDizzinessDrug Ineffective
Neonatal Respiratory Distress SyndromeCardiac FailureDepressionConfusional StateDiabetes MellitusDiabetes Mellitus Inadequate ControlType 2 Diabetes MellitusThrombocytopenia
Drug Exposure During PregnancyDeathDrug IneffectiveVision BlurredVomitingHyponatraemiaDepressionPain
HypotoniaDental CariesDiabetes MellitusBack PainDiabetes Mellitus Inadequate ControlHeadacheNauseaAtaxia
Weight IncreasedElevated MoodAngerAbdominal PainNauseaNeuropathy PeripheralVomitingOsteoarthritis
NephrolithiasisAppetite DecreasedSomnolenceWeight IncreasedSuicide AttemptInsomniaPainAnaemia
GastritisBlood Carbon Dioxide AbnormalAggressionAngerCardiac ArrestDizzinessCompleted SuicidePruritus

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Trileptal and Clonazepam?

You are not alone! Join a related mobile support group:
- support group for people who take Trileptal and Clonazepam
- support group for people who take Clonazepam
- support group for people who take Trileptal

Can you answer these questions (Ask a question):

  • I had bladder cancer and my doctor put me on metformin should i get off this
    I do not want to take this metformin if it may cause my bladder cancer to come badk
  • If you stop taking oxcarbazepine will your hair grow back?
    has been getting thinner on top and now there's a little bald spot it just seems like the last month and a half maybe that I've noticed that my hair has been getting thinner on top and now there's a little bald spot where its really thin and you can see the scalp and he increased my dosage by 600 milligrams
  • Can my eye twitch be because of lexapro?
    So I have had symptoms of anxiety and depression due to a lot of stressors and disasters that happened in my life over the past two years. As my anxiety got worse after a breast biopsy, I started freaking out and thinking I may have MS because my sister has MS. So I went to my GP and she decided my symptoms do not follow the symptoms of MS or any similar problem and it should most likely be anxiety. She put me on Lexapro and Clonazepam. At first I was very hesitant to take medication but as my symptoms got worse I decided to give it a try. I was on Lexopro 5 mg for about two months and then I went to 10 mg, and I would take 1 or 2 Clonazepam a day. And this all started 5 months ago. And things seemed to be working just fine.Until about two months ago I started having this freaking annoying eye twitch on my upper left eyelid. I have had eye twitches before but they always go away after a couple of days or a week top. This one has been lasting for 2 months now and seems to be just getting worse. I went to the GP and my eye doctor and they still found no cause and said it's probably stress and anxiety. I have not been overly stressed and I get plenty of sleep, 10 hrs or more! and I stopped taking caffeine and alcohol after the twitch started. Any idea? Could it be because of medication? I also need to add I have had thumb twitching and severe spasms in my muscles around my right thumb starting in May (before taking any medication).
  • Why would doctor prescribe meclizine when otc med available? stronger?
    Gastric bypass. After years found should not be prescribed extended release medications-- they do not work because stomach (duodenum) releases enzymes and acids to release XR. Suffer from GAD, MAD, PTSD, ADHD, Insomnia. I've driven away my best friend-- I'm tired of life-- alone.
  • Does "apraxia" of hand exist or is it called spasticity for tbi
    A moderate TBI secondary to a craniotomy effecting the frontal and temporal lobes.

More questions for: Clonazepam, Trileptal

You may be interested at these reviews (Write a review):

  • Panic after using flonase
    I was diagnosed with nasal polyps and put on Flonase (a steroid nose spray). It worked well to dry up post-nasal drip but I ended up with a bad case of panic and fear. I had overcome episodes of these nervous disorders but the Flonase brought it all back. I still suffer from panic even though I stopped the Flonase months ago. I had a bad attack on a bridge and also inside a grocery store. Personnel had to take me to the store office to calm me down. I am nearly agoraphobic now. I do go out alone but try to avoid after-dark. My life has been turned into daily dread of another attack. To think that I was more than ten years FREE of panic until I took the Flonase makes me feel so regretful that I ever took that stuff. It should be banned as there is enough evidence to do so from many people who now suffer debilitating and recurring panic.
  • A life of depression and fatigue
    1) Family history of depression, 2) Diagnosed depression 1964-not treated until 1973, 3) Worked in medical field 35 years, 4) Emergency on-call 24/7, 5) Hospital 15 times major depression, 6) Tried nearly all MAOI, TCA, SSRI, SNRI, and ECT. 7) 100% Disability in 1998 for depression. Now at age 70 I have dysthymia, chronic fatigue, COPD, and PTSD. My recommendation to younger people - do not over stress,
    do not smoke, avoid horrific or traumatic situations and try to find some enjoyment in life. If you have symptoms like mine seek early treatment put balance in your life. The often heard recommendations - get plenty of sleep, eat properly, learn to relax and avoid bad habits should not be ignored, they are critical to good physical and mental health.
  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
  • Could trileptal cause benign intracranial hypertension
    My Daughter is 9 and was on Trileptal for three years and just started to have severe headaches that lasted for two weeks and were quickly and poorly diagnosed as a status migraine. Another week of pain and incorrect treatments finally led to more tests and the correct diagnosis of IIH. Supposedly the most susceptible person (1 in 5,000) to get IIH in the US is an over weight female in her 20's. Based on my daughters information and the information on this site, Female Trileptal patients appear to have a 1 in 1500 chance of IIH and if you are female and also aged 2 to 9, your chances are about 1 in 250. Or 20 times more susceptible than heavy, adult females.

More reviews for: Clonazepam, Trileptal

Comments from related studies:

  • From this study (2 months ago):

  • I have been experiencing hair loss in clumps while running fingers through my hair and i have blurred vision. The hair loss is recent..within the last week..the newest medicine is the pantoprazole

    Reply

  • From this study (10 months ago):

  • Heartrace & elevated Blood Pressure come & go. Short shallow breathing,restlessness,some unknown agitation, & restlessness started when I started Paxil. These symptoms. come & go frequently ,& now after the Trileptin was started 3 days ago , my chest. has been hurting with increased. exercise & nigh sweats started while breathing issues & restlessness have increased. t to the point of not enough sleep . My bowels have been salty smelling. since new years eve due to an overdose on Tylenol extra strength & Klonopin ,which the ER gave me charcoal for,discharging me when the liver levels were okay

    Reply

  • From this study (1 year ago):

  • I am sleeping regularly. I wake up refreshed. Panic attacks have almost stopped completely. Appetite has returned. Able to laugh and enjoy music again. Stopped crying all the time. Irritability is gone..

    Reply

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Complete drug side effects:

On eHealthMe, Trileptal (oxcarbazepine) is often used to treat bipolar disorder. Clonazepam (clonazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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