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Review: Valium and Methadone





Summary: drug interactions are reported among people who take Valium and Methadone together.

This review analyzes the effectiveness and drug interactions between Valium and Methadone. It is created by eHealthMe based on reports of 2,084 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Valium and Methadone >>>

What are the drugs

Valium has active ingredients of diazepam. It is often used in stress and anxiety. (latest outcomes from Valium 21,816 users)

Methadone Hydrochloride has active ingredients of methadone hydrochloride. It is often used in pain. (latest outcomes from Methadone Hydrochloride 2,835 users)

On Nov, 26, 2014: 2,083 people who take Valium, Methadone Hydrochloride are studied

Valium, Methadone Hydrochloride outcomes

Drug combinations in study:
- Valium (diazepam)
- Methadone Hydrochloride (methadone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Valium is effective42.86%
(3 of 7 people)
55.56%
(5 of 9 people)
50.00%
(1 of 2 people)
33.33%
(1 of 3 people)
33.33%
(2 of 6 people)
33.33%
(1 of 3 people)
50.00%
(4 of 8 people)
100.00%
(1 of 1 people)
Methadone Hydrochloride is effective40.00%
(2 of 5 people)
50.00%
(2 of 4 people)
83.33%
(5 of 6 people)
80.00%
(4 of 5 people)
50.00%
(5 of 10 people)
40.00%
(2 of 5 people)
60.00%
(3 of 5 people)
100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DeathConstipationDysarthriaDental CariesElectrocardiogram Qt ProlongedConfusional StateQuadriparesisDrug Toxicity
SomnolenceVomitingDepressionDepressionSyncopeAnxietyComaCardiac Arrest
Completed SuicideOtorrhoeaDental CariesDrug DependenceDepressionAggressionMulti-organ FailureCompleted Suicide
DysarthriaSedationTooth AbscessDrug AbuseOverdoseMental DisorderDepressionRespiratory Arrest
VomitingDry SkinAtrial Septal DefectAbnormal BehaviourDrug Withdrawal ConvulsionsSuicidal IdeationFaecal IncontinenceCardio-respiratory Arrest
General Physical Health DeteriorationOropharyngeal PainVentricular Septal DefectDysarthriaDrug AbuseAbnormal BehaviourSuicidal IdeationPain
MalaiseHypotensionPatent Ductus ArteriosusTooth AbscessAbnormal BehaviourDepressionRespiratory ArrestAnxiety
Drug DependenceHyperhidrosisAbnormal BehaviourPartner StressMental DisorderBipolar DisorderFatigueDrug Dependence
Drug ToxicitySuicidal IdeationDrug DependenceOverdoseAnxietyParaesthesiaPain In ExtremityOverdose
Dental CariesHeadacheMaternal Drugs Affecting FoetusTooth LossSuicidal IdeationParosmiaIrritabilityDepression

Drug effectiveness by gender :

FemaleMale
Valium is effective47.37%
(9 of 19 people)
45.00%
(9 of 20 people)
Methadone Hydrochloride is effective61.90%
(13 of 21 people)
55.00%
(11 of 20 people)

Most common drug interactions by gender * :

FemaleMale
PainDrug Toxicity
DepressionPain
AnxietyCardiac Arrest
Drug ToxicityAnxiety
ArthralgiaDrug Dependence
ConstipationCompleted Suicide
Drug DependenceHeadache
Respiratory ArrestCardio-respiratory Arrest
Cardiac ArrestRespiratory Arrest
VomitingDrug Ineffective

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Valium is effectiven/an/an/a58.33%
(7 of 12 people)
20.00%
(4 of 20 people)
11.63%
(5 of 43 people)
16.67%
(2 of 12 people)
n/a
Methadone Hydrochloride is effectiven/an/an/a61.54%
(8 of 13 people)
33.33%
(7 of 21 people)
16.28%
(7 of 43 people)
16.67%
(2 of 12 people)
n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
NystagmusNystagmusCardiac ArrestDrug ToxicityCardiac ArrestPainCompleted SuicideCardiac Arrest
Congenital NystagmusDevelopmental DelayHypotensionRespiratory ArrestRespiratory ArrestDepressionCardiac ArrestRespiratory Arrest
Developmental DelayDrug Exposure During PregnancyPneumonitisCompleted SuicideDrug ToxicityHeadacheRespiratory ArrestDeath
Visual Acuity ReducedStrabismusAcute Respiratory Distress SyndromeMultiple Drug OverdoseArthralgiaConstipationDyspnoeaCompleted Suicide
StrabismusVisual Acuity ReducedBlood Bilirubin IncreasedTherapeutic Agent ToxicityCompleted SuicideDrug DependencePainCardio-respiratory Arrest
Strabismus CongenitalCongenital NystagmusPneumonia Respiratory Syncytial ViralCardio-respiratory ArrestCardio-respiratory ArrestAnxietyCardio-respiratory ArrestAnxiety
Optic Nerve HypoplasiaVisual ImpairmentRespiratory ArrestCardiac ArrestPain In ExtremityDrug ToxicityOedema PeripheralDehydration
Maternal Exposure During PregnancyPosture AbnormalHypernatraemiaOverdoseOedema PeripheralFatigueAnxietyPain
Drug Exposure During PregnancyDrug Withdrawal Syndrome NeonatalOverdoseAccidental OverdoseDrug DependenceInsomniaVomitingDisorientation
Visual ImpairmentMaternal Exposure During PregnancyRoad Traffic AccidentDrug AbuseSerotonin SyndromeBack PainDepressionDrug Ineffective

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Valium and Methadone?

You are not alone! Join a related mobile support group:
- support group for people who take Valium and Methadone
- support group for people who take Methadone Hydrochloride
- support group for people who take Valium

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

  • Can long-term methadone use cause or increase the risk of colon cancer?
    I had a two-level spinal fusion at L4-S1 in 2000 after being injuried at work in Sept. 24, 1997. I lost everything after...the unjury, ability to do my job, my wife and family (couldn't take the strain) my home, my sense of self and purpose, direction and belonging...credit rating and ability to pay my bills.
    After a long period of waiting to settle my workmens' comp. case, I returned home, from the Bat Area back to Arizona to take of my mother with a yet un dianosed case of moderate dementia.
    Then, in 2011 I had a 2nd surgery to relieve spinal stenosis btwn. L2-L4, just above the fusion site.
    I've been taking methadone since early 2004, a little over ten years, now. I've had high blood pressure since my injury.

    Now, I waiting to be scheduled for a colonoscopy, with my father having had polyps and the way I've been feeling..drained, tired all the time, and stomach pains ( in addition to my chronic low back pain), I...
    find myself wondering if there is any relationtionship between the methadone and other meds and cancer?
  • How many valium pills could causes coma
    I need to know how can one get in coma in a quick way
  • Can droopy eyelid be caused by a bump and/or pregabalin?
    Had a bad bump on my forehead a couple of weeks ago and my whole face went black. Mostly better now but Im let with a badly drooping eyelid (right) which the doctors tell me will go away. No sign of that at the moment but Ive read that pregabalin (which I take in small doses, can cause this. It is so bad and looks so different to the other eye (which is still tight enough to put makeup on) that unless I can find a better solution, I'll have to get it fixed cosmetically. Is two weeks a short time to expect it to be gone? Cheers
  • Can methadone cause my aynurism to burst?
    A doctor is lowering my dose of Methadone I take for severe back pain due to my aneurysm because he said the Methadone could cause a stroke w/my aneurysm. Has anyone else heard of this? Thank you!!!
  • What are the best meds to take to fix insomnia, anxiety,depression (2 answers)
    What medications will work well
    I need my brain to stop at night. And stay asleep.
    I have anxiety
    Little grumpy at times and things bother me a lot. Easily nervious and worry about everything. Crying a lot I notice.

More questions for: Methadone Hydrochloride, Valium

You may be interested at these reviews (Write a review):

  • 3 strong drugs together against neuropathic pain
    Neuropathic pain debuted when I was 24, now I'm 50. Received diagnosed with Ehler-Danlos syndrome (EDS), joint hypermobility type, when I was 35 years old. So it can take some time to get a diagnose. And as EDS-patient I do not belong to any clinic. Orthopedics says that EDS is not orthopedic, rheumatology says that EDS is not an autoimmune disease, GPs say that EDS is too difficult, and so on. Sooner or later we all end up at Psychiatry, even if we are not depressed.

    The first kind of pain I got when I was 24 came from low back, but I experienced as pelvic pain and leg pain. It was clearly a neuropathic pain, but it took years to find out. Later it was treated by a pain clinic with cortisone around the genitofemoral nerves (both sides). Since this treatment didn't result in lasting freedom from pain, the pain clinic started to give me RF (radio frequency) treatment. This made the pain disappeared after one year, and I was 80% free from it between 2002 and 2014, 12 years. The pain doctors said pain could return after 10 years.

    The other kind of neuropathic pain started 2003 with intense stomach pain. During 6 months I could hardly eat nothing due to nausea and vomiting. After this 6 months, stomach pain changed to almost unbearable pain in upper back.
    What happened 2003, and what all the doctors missed, was that the right lowest ribs slid up over the sternum. This rib dislocation is till there today, but now with a lot of cartilage formed around the rib where it is stuck in the lower end of the sternum. The dislocation is clearly visible on X-ray. This has greatly affected the thoracic spine. I have a scoliosis which I had not before 2003. And I still have severe pain in the thoracic spine.

    It was initially treated with morphine daily, and later with Durogesic (fentanyl), but this didn't help much. 2005 I was hospitalized because I had too much pain to take care of myself and my hygiene. After some months the doctors started to give me clonazepam because the muscles along the spine was in a chronic seizures. Clonazepam helped, but I could still have a lot of pain in two vertebrae in the thoracic spine. It felt as if someone drilled into the vertebrae without anesthesia. After a few months, doctors also prescribed me methadone. Then the pain disappeared almost completely. Since 2006, I have eaten clonazepam and methadone every day, and I need to sleep in an armchair to not get more pain because of moving during sleep.

    There are side effects. After 1,5 years with clonazepam and methadone I started to have panic attacks. Or rather one long panic attack which didn't stop before I got treatment with amitryptilin and pregabalin (Lyrica). These 2 medicines stopped the panic disorder completely after some hours, and the panic was then gone. Then I got side effects of these 2 medicines, amitryptilin & Lyrica, too. I gained a lot of weight (from 83 to 148 kg) and got much water (edema) in both my legs under the knees and in both feet. The feet could swallow to the double size. 2012 I stopped with amitryptilin and started to loose weight again (in Aug 2014 below 80 kg) and get less water in my legs. Today I eat as little medicines I can, but I have to take methadone, clonazepam and Lyrica every day, twice. If I try to take away one of these 3 medicines, I got pain problems at once. Lyrica is the most painful one to take away. In Sept-Dec 2013 I lowered Lyrica from 300 mg daily, to 150, then to 75 and finally 0 mg. The pain I had was extremely difficult to handle. It didn't help to take more methadone or anything else. I have checked on Internet and found that many people got pain from quitting with Lyrica. Most people start eating it again. So did I. But 2006 and 2007 it was enough to treat the pain with methadone and clonazepam, I got the Lyrica against anxiety not pain. But today I take Lyrica against pain.

    Beside weight gain and leg edema, clonazepam and Lyrica significantly affect the sexual desire. And Lyrica alone makes it almost impossible to ejaculate. All four drugs together (clonazepam, methadone, amitryptiline and Lyrica), make one forget all about sex life. You don't even miss it. When I stopped with amitryptiline and lowered Lyrica (still taking clonazepam and methadone), I could suddenly easily get erections again, feel desire, but not getting orgasms. This is quite difficult to deal with.

    The pain pattern is greatly affected, by pain and by the medicines. So is the mood. I get something which feels like heavy depression, especially if I take the medicines late that day. I should take a medicine like methadone 3 times a day, because the effects of the tablet lasts around 8 hours. But I take them every 12 hours, to have a low consumption in case doctors prescribe them too late (which happens, and then it's good to have a spouse going to the pharmacy buying them for you, because you have too much pain to go yourself).

    Since methadone is also used for treating heroine addicts, medical staff treat you with disrespect when they see that it says "methadone" in your health record. I need to show a certificate that says that I deal with chronic neuropathic pain, that I never have had problems with drug addiction, to get normal respect.

    I wanted to share this because I think I am alone in the world with these medicines in combination against neuropathic pain caused by hypermobile joints, joint dislocation and muscle spasms. After trying almost everything else, including surgery cutting nerves, methadone, clonazepam and Lyrica seems to be the only way to kill my pain. But it's a life where you always is questioned, because of the use of methadone. I can guarantee that everybody in the world should accept these medicines if they had experienced the unbearable pain I had in upper back before they started to give me clonazepam and methadone.
  • Nexium improves my constipation
    Started taking Nexium 1 week ago and I noticed improvement with my chronic constipation.
  • Had nms in 2005, will trileptal increase chance of recurrence?
    In 2005 I had NMS, which was not detected by my drs for 4 months. I'd been on Lexapro & Seroquel for 2 yrs, but was weaned from Lexapro & placed on Lamictal 3/05. Began getting low-grade fevers, which I was told were not caused by the Lamictal. I quit taking it anyway, fevers (along with uncontrollable shivering) continued & got higher. By 5/05 my temps were reaching 105 deg F. Husband said I became combative, refused to go to hospital. Early June/05 he came home to find me wrapped in blankets, with a temp over 105 F. He tried to place me in a tub of cold water, said I was rigid & screamed when he tried to move me. I was in the tub, speaking "in tongues" (his description, I have no memory of this). He called 911, took me to hospital. I woke, no idea where I was or why. After a lumbar puncture & 2 days in ICU I went home. The fevers continued...2 weeks later he came home to find me wrapped in sheets, towels, blankets, with the heat on full (it was in the 90's outside) he called ambulance again. I awoke to find myself under an ice blanket with nurses pushing large vials of dantrolene into both arms, several liters. Another LP, a stint in ICU...this time they told me it was NMS. The dr who dxd me said he was surprised I was alive, & not a vegetable, as my temp had peaked at 109 deg F. I suffered brain damage; short-term memory loss, brain can't control my body temp, my blood pressure went up. An arteriogram showed completely healthy heart & arteries, no plaque at all. I lost all body fat as well as some muscle mass. The fevers continued even after stopping the Seroquel. I visited my PCP for a checkup in 9/05, temp was normal. I started shuddering, my temp went up a full degree every 5 minutes. PCP admitted me to ER, my heart rate was over 272 B/M; they stopped my heart 3 times to "reset" it, which didn't work. I spent 3 days in hospital. Several months later my P doc tried me on Lamictal alone; I got Stevens-Johnson syndrome. I stopped the drug as soon as the signs appeared. I've been untreated, except for Neurontin & Primidone, until my manic episodes became unlivable. 3 weeks ago I went 8 days with no sleep, became psychotic. My P doc gave me Trileptal, which has evened my moods, but I've been getting low-grade fevers (highest was 103.6). Would having had NMS in the past make me more prone to falling to it again with the Trileptal? It's the only new med I've taken in over a year.
  • Crazy feelings with interesting things
    I am not tired but i can not keep my eyes open.I guess my Brain is tired, not my body. I can not focus on anything for a long period of time and when I try my eyes force close. I begin to hear voices and talk to people who are not present. I am scared so I stopped the meds slowly. Have not taken it in 36 hours and this morning I am still feeling this way.I am also on 4mg's of suboxone perscribed 3 times a day but I dont always take the 3rd one.
  • Heavy sweating during sleep
    Pain killers like Tylenol 3, vicodin 20 years, Valium and Soma 12 years. Sweat heavy during sleep.

More reviews for: Methadone Hydrochloride, Valium

Comments from related studies:

  • From this study (1 year ago):

  • Not taking meds for mental issues mental health has berm getting worse over the past few years and is now rapidly deteriorating

    Reply

  • From this study (2 years ago):

  • i have been on all these medications long term and i am always tired, no energy and feel depressed. want to come of them all but dont know the safest way, please help

    Reply

    PIERRE THE BEAR (1 NATION HURON ) on Feb, 11, 2013:

    i would tamper off medication real slow.. so not to get real heavy withdrawels........ here,s how to do it ...it realy worked for me comming off diazapam ..a realy evil pill to get off ove.... so you start by only taking 0.5 off your medication per 3 to 4 weeks..get it ..you do this for 3 to 4 weeks..ok..then tapper off another 0.5 for another 3 to 4 weeks...you do that till your 0.5... but you have to do 0.5 too 3 to 4 weeks to ..ok..then do 0.5 every few days for 3 to 4 weeks... then go for the withdrawels./..they should not be so bad... even when they get hard on you ...do not give up ok...good luck my friends....pierre the bear.

    Reply

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Complete drug side effects:

On eHealthMe, Valium (diazepam) is often used to treat stress and anxiety. Methadone Hydrochloride (methadone hydrochloride) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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