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Review: Vicodin and Cymbalta

This review analyzes the effectiveness and drug interactions between Vicodin and Cymbalta. It is created by eHealthMe based on reports of 3,794 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Vicodin and Cymbalta >>>

What are the drugs

Vicodin (what 35,289 Vicodin users reported?) has active ingredients of acetaminophen; hydrocodone bitartrate. It is used in pain.

Cymbalta (what 49,154 Cymbalta users reported?) has active ingredients of duloxetine hydrochloride. It is used in depression.

On Aug, 12, 2014: 3,794 people who take Vicodin, Cymbalta are studied

Vicodin, Cymbalta outcomes

Drug combinations in study:
- Vicodin (acetaminophen; hydrocodone bitartrate)
- Cymbalta (duloxetine hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Vicodin is effective26.47%
(9 of 34 people)
37.25%
(19 of 51 people)
56.67%
(17 of 30 people)
35.19%
(19 of 54 people)
42.86%
(30 of 70 people)
42.11%
(16 of 38 people)
31.25%
(5 of 16 people)
0.00%
(0 of 3 people)
Cymbalta is effective11.76%
(4 of 34 people)
31.82%
(21 of 66 people)
27.03%
(10 of 37 people)
26.67%
(12 of 45 people)
36.76%
(25 of 68 people)
25.00%
(6 of 24 people)
37.50%
(3 of 8 people)
0.00%
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
AnxietyDizzinessAnxietyDrug IneffectiveDepressionDepressionNauseaPain
FallPainFeeling AbnormalInsomniaAnxietyAnxietyFatigueAnxiety
Suicidal IdeationHeadacheMalaiseDepressionPainDrug Withdrawal SyndromeDeep Vein ThrombosisNausea
DyspnoeaAspartate Aminotransferase IncreasedDepressed MoodAnxietyConstipationFatiguePulmonary EmbolismFall
Drug IneffectiveAlanine Aminotransferase IncreasedSuicidal IdeationArthralgiaRoad Traffic AccidentDrug IneffectiveConstipationDepression
IrritabilityNauseaPain In ExtremityMental Status ChangesPancreatitisNauseaDrug DependenceBack Pain
NauseaLoss Of ConsciousnessDrug Withdrawal SyndromeSuicidal IdeationSuicide AttemptPainCryingHeadache
FatigueDrug IneffectiveAngerMental DisorderInsomniaSuicide AttemptMouth Ulceration AggravatedInsomnia
AstheniaInsomniaDrug Clearance DecreasedAstheniaHeadacheJoint PainAnxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, TensionArthralgia
MalaiseBlood Alkaline Phosphatase IncreasedAbnormal BehaviourPainTardive DyskinesiaDyspnoeaShortness Of BreathFatigue

Drug effectiveness by gender :

FemaleMale
Vicodin is effective38.86%
(89 of 229 people)
38.81%
(26 of 67 people)
Cymbalta is effective29.86%
(66 of 221 people)
24.19%
(15 of 62 people)

Most common drug interactions by gender * :

FemaleMale
PainPain
AnxietyAnxiety
NauseaDepression
FallFall
DepressionBack Pain
ArthralgiaNausea
HeadacheFatigue
InsomniaInsomnia
Back PainHeadache
FatigueWeight Decreased

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Vicodin is effectiven/an/a100.00%
(1 of 1 people)
38.46%
(10 of 26 people)
15.50%
(20 of 129 people)
21.89%
(37 of 169 people)
26.32%
(35 of 133 people)
20.69%
(12 of 58 people)
Cymbalta is effectiven/an/a100.00%
(1 of 1 people)
32.00%
(8 of 25 people)
12.39%
(14 of 113 people)
15.52%
(27 of 174 people)
19.26%
(26 of 135 people)
8.47%
(5 of 59 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Meningomyelocelen/aCholecystitis ChronicPainDepressionPainPainFall
Neural Tube DefectPainNauseaPainHeadacheAnxietyPain
Spina BifidaGallbladder DisorderPneumoniaNauseaFatigueNauseaAnxiety
TalipesAbdominal Pain UpperAbdominal Pain UpperAnxietyAnxietyFallNausea
Maternal Drugs Affecting FoetusSphincter Of Oddi DysfunctionInsomniaWeight IncreasedNauseaArthralgiaBack Pain
Congenital HydrocephalusHeadacheVomitingArthralgiaFallInsomniaHypertension
ObesityPancreatitisCholecystitis ChronicAbdominal Pain UpperDepressionPyrexiaDepression
Type 2 Diabetes MellitusBone InfarctionAnxietyDrug IneffectiveBack PainDiarrhoeaFatigue
Abortion InducedArthropathyHeadacheWeight DecreasedVomitingInjuryDyspnoea
Congenital Central Nervous System AnomalyBone PainMigraineSuicidal IdeationHypoaesthesiaDepressionAsthenia

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group to help out with your experience or learn from others anytime and anywhere:
- group for people who take Vicodin and Cymbalta
- group for people who take Cymbalta
- group for people who take Vicodin

Comments from related studies:

  • From this study (2 weeks ago):

  • I went to a Rheumatologist and he said I have Hashimoto disease and said its not serious enough to take meds for. The test is - Thyroid Peroxidase Antiboties - my number is 363. It says that is should be <9. I was wondering if these medications I am on could be causing abnormal reading. I do have severe inflammation due to serious injuries.

    Reply

  • From this study (2 months ago):

  • Have had unidentified autoimmune disease for five years, elevated cardiac enzymes from coronary vasospasms, joint pain, arthritis, muscle weakness, muscle tears

    Reply

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Complete drug side effects:

On eHealthMe, Vicodin (acetaminophen; hydrocodone bitartrate) is often used to treat pain. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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