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Review: Vyvanse and Wellbutrin

This review analyzes the effectiveness and drug interactions between Vyvanse and Wellbutrin. It is created by eHealthMe based on reports of 375 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Vyvanse and Wellbutrin >>>

What are the drugs

Vyvanse (latest outcomes from 7,718 users) has active ingredients of lisdexamfetamine dimesylate. It is used in attention deficit hyperactivity disorder.

Wellbutrin (latest outcomes from 54,804 users) has active ingredients of bupropion hydrochloride. It is used in depression.

On Aug, 12, 2014: 375 people who take Vyvanse, Wellbutrin are studied

Vyvanse, Wellbutrin outcomes

Drug combinations in study:
- Vyvanse (lisdexamfetamine dimesylate)
- Wellbutrin (bupropion hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Vyvanse is effective36.84%
(7 of 19 people)
28.95%
(11 of 38 people)
38.71%
(12 of 31 people)
55.00%
(22 of 40 people)
53.33%
(16 of 30 people)
50.00%
(2 of 4 people)
100.00%
(1 of 1 people)
33.33%
(1 of 3 people)
Wellbutrin is effective9.09%
(1 of 11 people)
26.47%
(9 of 34 people)
30.00%
(6 of 20 people)
34.48%
(10 of 29 people)
30.23%
(13 of 43 people)
41.18%
(7 of 17 people)
55.56%
(5 of 9 people)
0.00%
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DepressionNauseaDepressionErectile DysfunctionExhaustion, Fatigue, Lethargy, Tiredness, WearinessDizzinessSpottingDrug Ineffective
AngerExhaustion, Fatigue, Lethargy, Tiredness, WearinessNauseaDrug IneffectiveFatigueAngerSexual DysfunctionDepression
Blood Pressure IncreasedAngerHeadacheDry MouthErectile DysfunctionCryingAnorgasmiaNausea
Suicidal IdeationDepressionDrug AbuseAppetite DecreasedConstipationMultiple Chemical SensitivityHeadache - TensionFatigue
HeadacheIrritabilityDrug Effect DecreasedAnxietyPain - JointsNauseaOverdose
Depressed MoodFatigueAngerLoss Of AppetiteMuscle TightnessHair LossSuicidal Ideation
Drug IneffectiveAnxietyIbsFaintingSleepinessDepressionAnger
AnxietyAttention Deficit/hyperactivity DisorderAnxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, TensionDry EyesOvulation InductionDrug AbuseDisturbance In Attention
Decreased AppetiteMuscle RigidityGastroparesisTremorTachycardiaOverdoseAnxiety
AstheniaTachycardiaConversion DisorderSweating - ExcessiveNauseaTheftDry Mouth

Drug effectiveness by gender :

FemaleMale
Vyvanse is effective39.66%
(46 of 116 people)
52.00%
(26 of 50 people)
Wellbutrin is effective31.30%
(36 of 115 people)
29.17%
(14 of 48 people)

Most common drug interactions by gender * :

FemaleMale
DepressionDrug Ineffective
NauseaAnger
FatigueErectile Dysfunction
Drug IneffectiveSuicidal Ideation
OverdoseBlood Pressure Increased
AnxietyFatigue
AngerDisturbance In Attention
Suicidal IdeationRectal Haemorrhage
Mood SwingsHyperhidrosis
TremorTherapeutic Response Unexpected

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Vyvanse is effectiven/an/a14.29%
(3 of 21 people)
27.47%
(25 of 91 people)
27.27%
(21 of 77 people)
25.86%
(15 of 58 people)
14.63%
(6 of 41 people)
50.00%
(2 of 4 people)
Wellbutrin is effectiven/an/a9.52%
(2 of 21 people)
18.60%
(16 of 86 people)
14.47%
(11 of 76 people)
20.31%
(13 of 64 people)
16.28%
(7 of 43 people)
50.00%
(1 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aNegativismAngerDrug IneffectiveNauseaDrug IneffectiveDrug IneffectiveMusculoskeletal Disorder
AngerInsomniaAutoimmune DisorderDizzinessDepressionOverdoseAccident
Abnormal BehaviourDepressionPyrexiaFatigueSuicidal IdeationAmnesiaLower Limb Fracture
AgitationMiddle InsomniaVisual Field DefectHeadacheAstheniaRashUpper Limb Fracture
Weight DecreasedTardive DyskinesiaVisual ImpairmentAbdominal PainDepressed MoodFatigueFeeling Abnormal
Drug Administration ErrorCryingPhotopsiaGastritisFatigueDiabetes MellitusWrist Fracture
Drug IneffectiveConvulsionOverdoseMenorrhagiaAnxietyAnxietyMultiple Fractures
Mood SwingsDisturbance In AttentionRetinal DisorderDehydrationRectal HaemorrhageNauseaLimb Crushing Injury
AggressionDrug Screen PositiveVasculitisInfluenzaTherapeutic Response UnexpectedParaesthesiaSpinal Fracture
Suicidal IdeationOedema PeripheralPain - JointsAngerMental ImpairmentPelvic Fracture

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group to help out with your experience or learn from others anytime and anywhere:
- group for people who take Vyvanse and Wellbutrin
- group for people who take Vyvanse
- group for people who take Wellbutrin

Comments from related studies:

  • From this study (1 month ago):

  • Alpha Liponic Acid....kidney failure < month
    Critical Liver Support...Kidney failure < month
    Charcoal Activated... Absorb impurities < month

    Reply

  • From this study (2 months ago):

  • My blood pressure is around 100-110 over 64-70 on days when I take no Vyvanse. On days that I take Vyvanse its around 157 over 88. But the Vyvanse helps my ADD.

    Reply

  • From this study (3 months ago):

  • Time hallucinations started 3 am; vyvanse taken at 11 am previous day; ambien taken at 11 pm; had 1 uncontrollable muscle movement at 4 am in my neck and jerked head back; felt very anxious and paranoid.

    Reply

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Complete drug side effects:

On eHealthMe, Vyvanse (lisdexamfetamine dimesylate) is often used to treat attention deficit hyperactivity disorder. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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