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Review: Vyvanse and Wellbutrin

This review analyzes the effectiveness and drug interactions between Vyvanse and Wellbutrin. It is created by eHealthMe based on reports of 376 people who take the same drugs from FDA and social media, and is updated regularly.

Get connected: join a mobile support group for people who take Vyvanse and Wellbutrin >>>

What are the drugs

Vyvanse (latest outcomes from 7,751 users) has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder.

Wellbutrin (latest outcomes from 54,854 users) has active ingredients of bupropion hydrochloride. It is often used in depression.

On Sep, 11, 2014: 376 people who take Vyvanse, Wellbutrin are studied

Vyvanse, Wellbutrin outcomes

Drug combinations in study:
- Vyvanse (lisdexamfetamine dimesylate)
- Wellbutrin (bupropion hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Vyvanse is effective36.84%
(7 of 19 people)
28.95%
(11 of 38 people)
38.71%
(12 of 31 people)
55.00%
(22 of 40 people)
54.84%
(17 of 31 people)
50.00%
(2 of 4 people)
100.00%
(1 of 1 people)
33.33%
(1 of 3 people)
Wellbutrin is effective9.09%
(1 of 11 people)
26.47%
(9 of 34 people)
30.00%
(6 of 20 people)
34.48%
(10 of 29 people)
30.23%
(13 of 43 people)
44.44%
(8 of 18 people)
55.56%
(5 of 9 people)
0.00%
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DepressionNauseaDepressionErectile DysfunctionExhaustion, Fatigue, Lethargy, Tiredness, WearinessDizzinessSpottingDrug Ineffective
AngerExhaustion, Fatigue, Lethargy, Tiredness, WearinessNauseaDrug IneffectiveFatiguePndSexual DysfunctionDepression
Blood Pressure IncreasedAngerHeadacheDry MouthErectile DysfunctionAngerAnorgasmiaNausea
Suicidal IdeationDepressionDrug AbuseAppetite DecreasedConstipationMultiple Chemical SensitivityHeadache - TensionFatigue
HeadacheIrritabilityDrug Effect DecreasedAnxietyPain - JointsNauseaOverdose
Depressed MoodFatigueAngerLoss Of AppetiteMuscle TightnessCryingSuicidal Ideation
Drug IneffectiveAnxietyIbsFaintingSleepinessDepressionAnger
AnxietyAttention Deficit/hyperactivity DisorderAnxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, TensionDry EyesOvulation InductionOverdoseDisturbance In Attention
Decreased AppetiteMuscle RigidityGastroparesisTremorTachycardiaTheftAnxiety
AstheniaTachycardiaConversion DisorderSweating - ExcessiveNauseaInsomniaDry Mouth

Drug effectiveness by gender :

FemaleMale
Vyvanse is effective40.17%
(47 of 117 people)
52.00%
(26 of 50 people)
Wellbutrin is effective31.90%
(37 of 116 people)
29.17%
(14 of 48 people)

Most common drug interactions by gender * :

FemaleMale
DepressionDrug Ineffective
NauseaAnger
FatigueErectile Dysfunction
Drug IneffectiveSuicidal Ideation
OverdoseBlood Pressure Increased
AnxietyFatigue
AngerDisturbance In Attention
Suicidal IdeationRectal Haemorrhage
Mood SwingsHyperhidrosis
IrritabilityTherapeutic Response Unexpected

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Vyvanse is effectiven/an/a14.29%
(3 of 21 people)
27.47%
(25 of 91 people)
27.85%
(22 of 79 people)
25.86%
(15 of 58 people)
14.63%
(6 of 41 people)
50.00%
(2 of 4 people)
Wellbutrin is effectiven/an/a9.52%
(2 of 21 people)
18.60%
(16 of 86 people)
15.38%
(12 of 78 people)
20.31%
(13 of 64 people)
16.28%
(7 of 43 people)
50.00%
(1 of 2 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aNegativismAngerDrug IneffectiveNauseaDrug IneffectiveDrug IneffectiveMusculoskeletal Disorder
AngerInsomniaAutoimmune DisorderFatigueDepressionOverdoseAccident
Abnormal BehaviourDepressionPyrexiaDizzinessSuicidal IdeationAmnesiaLower Limb Fracture
AgitationMiddle InsomniaVisual Field DefectHeadacheAstheniaRashUpper Limb Fracture
Weight DecreasedTardive DyskinesiaVisual ImpairmentAbdominal PainDepressed MoodFatigueFeeling Abnormal
Drug Administration ErrorCryingPhotopsiaDehydrationFatigueDiabetes MellitusWrist Fracture
Drug IneffectiveConvulsionOverdoseDrug Effect DecreasedAnxietyAnxietyMultiple Fractures
Mood SwingsDisturbance In AttentionRetinal DisorderGastritisRectal HaemorrhageNauseaLimb Crushing Injury
AggressionDrug Screen PositiveVasculitisInfluenzaTherapeutic Response UnexpectedParaesthesiaSpinal Fracture
Suicidal IdeationOedema PeripheralAbdominal Pain UpperAngerMental ImpairmentPelvic Fracture

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Vyvanse and Wellbutrin?

Get connected! Join a mobile support group:
- group for people who take Vyvanse and Wellbutrin
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- group for people who take Wellbutrin

Comments from related studies:

  • From this study (2 months ago):

  • Alpha Liponic Acid....kidney failure < month
    Critical Liver Support...Kidney failure < month
    Charcoal Activated... Absorb impurities < month

    Reply

  • From this study (4 months ago):

  • My blood pressure is around 100-110 over 64-70 on days when I take no Vyvanse. On days that I take Vyvanse its around 157 over 88. But the Vyvanse helps my ADD.

    Reply

  • From this study (4 months ago):

  • Time hallucinations started 3 am; vyvanse taken at 11 am previous day; ambien taken at 11 pm; had 1 uncontrollable muscle movement at 4 am in my neck and jerked head back; felt very anxious and paranoid.

    Reply

Post a new comment    OR    Read more comments

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Complete drug side effects:

On eHealthMe, Vyvanse (lisdexamfetamine dimesylate) is often used to treat attention deficit hyperactivity disorder. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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