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Review: taking Vyvanse and Wellbutrin together

Summary: drug interactions are reported among people who take Vyvanse and Wellbutrin together.

This review analyzes the effectiveness and drug interactions between Vyvanse and Wellbutrin. It is created by eHealthMe based on reports of 380 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Vyvanse and Wellbutrin >>>

What are the drugs

Vyvanse has active ingredients of lisdexamfetamine dimesylate. It is often used in attention deficit hyperactivity disorder. (latest outcomes from 7,873 Vyvanse users)

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from 55,057 Wellbutrin users)

On Feb, 26, 2015: 380 people who take Vyvanse, Wellbutrin are studied

Vyvanse, Wellbutrin outcomes

Drug combinations in study:
- Vyvanse (lisdexamfetamine dimesylate)
- Wellbutrin (bupropion hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Vyvanse is effective36.84%
(7 of 19 people)
30.77%
(12 of 39 people)
38.71%
(12 of 31 people)
56.10%
(23 of 41 people)
53.12%
(17 of 32 people)
50.00%
(2 of 4 people)
50.00%
(1 of 2 people)
33.33%
(1 of 3 people)
Wellbutrin is effective9.09%
(1 of 11 people)
25.00%
(9 of 36 people)
30.00%
(6 of 20 people)
33.33%
(10 of 30 people)
31.82%
(14 of 44 people)
44.44%
(8 of 18 people)
55.56%
(5 of 9 people)
0.00%
(0 of 2 people)

Drug effectiveness by gender :

FemaleMale
Vyvanse is effective40.00%
(48 of 120 people)
52.94%
(27 of 51 people)
Wellbutrin is effective31.93%
(38 of 119 people)
28.57%
(14 of 49 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Vyvanse is effectiven/an/a13.64%
(3 of 22 people)
28.26%
(26 of 92 people)
28.05%
(23 of 82 people)
25.86%
(15 of 58 people)
14.63%
(6 of 41 people)
50.00%
(2 of 4 people)
Wellbutrin is effectiven/an/a13.64%
(3 of 22 people)
18.39%
(16 of 87 people)
14.81%
(12 of 81 people)
20.31%
(13 of 64 people)
16.28%
(7 of 43 people)
50.00%
(1 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DepressionNauseaDepressionErectile DysfunctionExhaustion, Fatigue, Lethargy, Tiredness, WearinessDizzinessSpottingDrug Ineffective
AngerExhaustion, Fatigue, Lethargy, Tiredness, WearinessNauseaDrug IneffectiveFatiguePndSexual DysfunctionDepression
Blood Pressure IncreasedIrritabilityHeadacheDry MouthErectile DysfunctionAngerAnorgasmiaNausea
Suicidal IdeationAngerDrug AbuseAnxietyConstipationMultiple Chemical SensitivityHeadache - TensionFatigue
HeadacheAttention Deficit/hyperactivity DisorderDrug Effect DecreasedAppetite DecreasedPain - JointsNauseaOverdose
Depressed MoodFatigueAngerFaintingMuscle TightnessCryingSuicidal Ideation
Drug IneffectiveDrug IneffectiveIbsDry EyesSleepinessDepressionAnger
AnxietyMood SwingsAnxiety, Apprehension, Feeling Uptight, Jitters, Stress, Stress And Anxiety, TensionLoss Of AppetiteOvulation InductionOverdoseDisturbance In Attention
Decreased AppetiteDepressionGastroparesisTremorTachycardiaTheftAnxiety
AstheniaTachycardiaConversion DisorderMetallic TasteNauseaInsomniaDry Mouth

Most common drug interactions by gender * :

FemaleMale
DepressionDrug Ineffective
NauseaAnger
FatigueErectile Dysfunction
Drug IneffectiveSuicidal Ideation
OverdoseBlood Pressure Increased
AnxietyFatigue
Suicidal IdeationDisturbance In Attention
AngerRectal Haemorrhage
Mood SwingsHyperhidrosis
HeadacheTherapeutic Response Unexpected

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
n/aNegativismInsomniaDrug IneffectiveNauseaDrug IneffectiveDrug IneffectiveMusculoskeletal Disorder
AngerAngerAutoimmune DisorderDizzinessDepressionOverdoseAccident
Abnormal BehaviourDepressionPyrexiaFatigueSuicidal IdeationAmnesiaLower Limb Fracture
AgitationConvulsionVisual Field DefectHeadacheAstheniaRashUpper Limb Fracture
Weight DecreasedTardive DyskinesiaVisual ImpairmentAbdominal PainDepressed MoodFatigueFeeling Abnormal
Drug Administration ErrorSuicidal IdeationPhotopsiaAbdominal Pain UpperFatigueDiabetes MellitusWrist Fracture
Drug IneffectiveDisturbance In AttentionOverdoseGastritisAnxietyAnxietyMultiple Fractures
Mood SwingsMiddle InsomniaRetinal DisorderDehydrationRectal HaemorrhageNauseaLimb Crushing Injury
AggressionDrug Screen PositiveVasculitisMenorrhagiaTherapeutic Response UnexpectedParaesthesiaSpinal Fracture
CryingOedema PeripheralSomnolenceAngerMental ImpairmentPelvic Fracture

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Get connected: join our support group of Vyvanse and Wellbutrin on

Do you take Vyvanse and Wellbutrin?

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- support group for people who take Vyvanse and Wellbutrin
- support group for people who take Vyvanse
- support group for people who take Wellbutrin

Can you answer these questions (Ask a question):

More questions for: Vyvanse, Wellbutrin

You may be interested at these reviews (Write a review):

  • Longterm vyvanse use and myocarditis
    At 19 years old, I suddenly had a heart attack out of no where that left me with chronic myocarditis and pericarditis. I was perfectly healthy, did not use drugs, ate well, and exercised daily. The doctors could not come up with any explanation, but assumed it was an autoimmune disease. Neither heart disease nor autoimmune disease run in my family and the rheumatologist could not find any abnormalities. The only thing that I can come to think that caused this disease for me is taking vyvanse for about 5 years. Since then I have refused to take it, and it took me over a year for my heart to all most fully recover(it will never be fully recovered). I just want to know if there is anyone else out there who have suffered from a similar situation as me.
  • Lamotrigine severe rash
    I started taking 100mg of Teva-Lamotrigine Nov 22 once daily. I got a refill on Dec 5 that was Mylan-Lamotrigine. Two days later I woke up with an odd hot feeling rash all over my body and severe fatigue. I went back to bed 1/2 hour later after taking my regular Wellbutrin and the Lamotrigine. I woke up late morning. It got progressively worse during the day and I had a headache,fever and chills. I took the anti-histimine Aerius later that day which didn't help. The next day I went to a walk in clinic and they said it wasn't the Lamotrigine and thought it was a virus and did a throat swab. The fever and chills went away after a few days but I still have the rash. Finally after a week I saw a doctor that agreed it was the drug and I am now on the second week of Prednisone steroid treatment and prescription Reactin which is helping slowly. I have reported it to the Mylan drug company.
  • The zoloft/vyvanse concoction ruined my life.
    I started taking these drugs about two months ago. I am diagnosed ADHD by a psychiatrist. I received these medications from a doctor whom I know and is married to a friend my wife. She, the doctor, gave them to me from her personal medications in a plastic baggy. I was given loose instructions for taking these on a piece of paper. I was never given the paperwork with warning signs. 10 days after starting these medications, I attacked my wife and am now separated. I am barred from seeing her and my daughter by means of a Victims Protective Order. I am a normally nonviolent person. Most who know me call me a peacemaker...a pacifist. I am still horrified by the events of that night. 15 seconds changed my life forever. I hope and pray my story helps others. Don't be naïve, as I was, when given medications. Ask questions.
  • Intrsoccular pressure increase associated with wellbutrin
    I was given a prescription for Wellbutrin in approximately 1998. I had has my ocular pressure checked a year prior to this and it was okay. At the time, I only needed to wear reading glasses, common in people over 45. I took the drug at the full prescribed dosage for two weeks. Immediately prior to the narrow angle glaucoma episode, my vision had actually seemed to improve. For one day, prior, I could read without reading glasses. The following night, I was watching tv, and things suddenly became foggy. It was actually as if a fog had enveloped the room. I could not see anything except to discern between light and dark areas. I had to have emergency laser surgery the next morning. I mentioned to the doctor that Iwas taking Wellbutrin to stop smoking, and asked if it could have caused the ocular pressure increase. he consulted the PDR, and said there was no mention of it causing increases in ocular pressure. One year later my primary care doctor again insisted that I stop smoking, and again I mentioned that I thought it might increase ocular pressure. She told me to take a half dose, I did, and I took it one week, at which time I again experienced another episode of narrow angle glaucoma. When I go to the doctor's office my pressure in my left eye was 72, and 68 in my right eye. I was then referred on a triage basis to another doctor. I spent the rest of the day in his office having drops administered every fifteen minutes(extremely painful). I had extensive laser surgery the next morning.It required over fifty shots from the laser machine into each eye, (also extremely painful). I had lost considerable peripheral AND CENTRAL VISION in my left eye, and a good deal in my right. As a result of having to have such extensive laser surgery I also had cataracts that began at 50% maturity. I was advised by the surgeon that I should wait to have the cataracts removed "until my vision and quality of life was so poor that I was ready to commit suicide" because having the cataracts removed would cause the pressure in my eyes to become very difficult to control, and that more than likely I would end up being black blind. I would never use Wellbutrin under any circumstances, and I always check to make sure that any new meds I may be put on don't have anything to do with an increase in ocular pressure. If they do, I refuse to take them. The surgeon said he was surprised that I didn't lose more vision than I did, and I am grateful that I didn't, and that he was a good surgen. He wrote an article concerning this case for a medical journal since he said he had been seeing a recent increase of narrow angle glaucoma.
  • Librium 25mg and wellbutrin 300mg for >1 month
    I've been taking librium twice daily, morning and night, for about 3 months now along with wellbutrin XL in the morning. I've basically had the mood of "I don't care" and a great boost in confidence.

More reviews for: Vyvanse, Wellbutrin

Comments from related studies:

  • From this study (8 months ago):

  • Alpha Liponic Acid....kidney failure < month
    Critical Liver Support...Kidney failure < month
    Charcoal Activated... Absorb impurities < month

    Reply

  • From this study (9 months ago):

  • My blood pressure is around 100-110 over 64-70 on days when I take no Vyvanse. On days that I take Vyvanse its around 157 over 88. But the Vyvanse helps my ADD.

    Reply

  • From this study (9 months ago):

  • Time hallucinations started 3 am; vyvanse taken at 11 am previous day; ambien taken at 11 pm; had 1 uncontrollable muscle movement at 4 am in my neck and jerked head back; felt very anxious and paranoid.

    Reply

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Complete drug side effects:

On eHealthMe, Vyvanse (lisdexamfetamine dimesylate) is often used to treat attention deficit hyperactivity disorder. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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