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Review: taking Wellbutrin and Trazodone together

Summary: drug interactions are reported among people who take Wellbutrin and Trazodone together.

This review analyzes the effectiveness and drug interactions between Wellbutrin and Trazodone. It is created by eHealthMe based on reports of 3,752 people who take the same drugs from FDA and social media, and is updated regularly.

 

 

 

 

You are not alone: join a mobile support group for people who take Wellbutrin and Trazodone >>>

What are the drugs

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from 55,068 Wellbutrin users)

Trazodone hydrochloride has active ingredients of trazodone hydrochloride. It is often used in insomnia. (latest outcomes from 6,654 Trazodone hydrochloride users)

On Mar, 5, 2015: 3,752 people who take Wellbutrin, Trazodone Hydrochloride are studied

Wellbutrin, Trazodone Hydrochloride outcomes

Drug combinations in study:
- Wellbutrin (bupropion hydrochloride)
- Trazodone Hydrochloride (trazodone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Wellbutrin is effective16.13%
(5 of 31 people)
36.67%
(22 of 60 people)
19.35%
(6 of 31 people)
39.13%
(18 of 46 people)
43.33%
(26 of 60 people)
59.18%
(29 of 49 people)
65.71%
(23 of 35 people)
16.67%
(1 of 6 people)
Trazodone Hydrochloride is effective39.39%
(13 of 33 people)
49.18%
(30 of 61 people)
34.38%
(11 of 32 people)
59.52%
(25 of 42 people)
53.73%
(36 of 67 people)
75.00%
(36 of 48 people)
62.07%
(18 of 29 people)
40.00%
(2 of 5 people)

Drug effectiveness by gender :

FemaleMale
Wellbutrin is effective42.68%
(102 of 239 people)
36.00%
(27 of 75 people)
Trazodone Hydrochloride is effective57.85%
(140 of 242 people)
41.33%
(31 of 75 people)

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Wellbutrin is effectiven/an/a16.67%
(2 of 12 people)
20.00%
(14 of 70 people)
22.45%
(22 of 98 people)
25.29%
(43 of 170 people)
21.01%
(29 of 138 people)
22.89%
(19 of 83 people)
Trazodone Hydrochloride is effectiven/an/a58.33%
(7 of 12 people)
31.67%
(19 of 60 people)
34.65%
(35 of 101 people)
29.41%
(45 of 153 people)
26.62%
(37 of 139 people)
33.33%
(28 of 84 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
AnxietyDepressionType 2 Diabetes MellitusType 2 Diabetes MellitusDepressionType 2 Diabetes MellitusDiabetic RetinopathyDepression
DepressionInsomniaDiabetes MellitusPainSuicidal IdeationDiabetes MellitusWeight IncreasedPain
TremorType 2 Diabetes MellitusHysterectomyConvulsionPainDepressionDiabetes Mellitus Inadequate ControlAnxiety
NauseaPainBack PainWeight IncreasedAnxietyAnxietyProteinuriaDiabetes Mellitus
InsomniaHeadacheInflammationHypertensionWeight DecreasedBlood Triglycerides IncreasedBlood Glucose IncreasedNausea
DizzinessBlood Cholesterol IncreasedHeadachePulmonary EmbolismSuicide AttemptObesityDiabetic NeuropathyType 2 Diabetes Mellitus
Suicide AttemptAnxietyGastric UlcerAnxietyPancreatitisInsomniaRenal DisorderFatigue
Drug IneffectiveDiabetes MellitusBladder DisorderNauseaHallucinationSuicidal IdeationDiabetic Eye DiseaseWeight Increased
VomitingCompleted SuicideFungal InfectionObesityTardive DyskinesiaMental DisorderTremorVomiting
HyperlipidaemiaFatigueNauseaDiabetes MellitusConvulsionNeoplasmInsomniaInsomnia

Most common drug interactions by gender * :

FemaleMale
DepressionDepression
NauseaDiabetes Mellitus
AnxietyAnxiety
PainPain
Diabetes MellitusType 2 Diabetes Mellitus
Type 2 Diabetes MellitusInsomnia
FatigueFatigue
Weight IncreasedConstipation
DiarrhoeaBack Pain
HeadacheWeight Decreased

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Type 2 Diabetes MellitusLethargyWeight IncreasedCompleted SuicideDiabetes MellitusDiabetes MellitusDepressionMyocardial Infarction
PancreatitisGruntingAnxietyCardiac ArrestType 2 Diabetes MellitusType 2 Diabetes MellitusPainDepression
Pancreatitis AcuteDysarthriaSuicidal IdeationType 2 Diabetes MellitusNauseaDepressionNauseaTremor
Pelvic Fluid CollectionRespiratory Rate IncreasedAggressionAnxietyWeight IncreasedNauseaAnxietyDrug Ineffective
Neuroleptic Malignant SyndromeDrug IneffectiveNauseaDiabetes MellitusDiabetes Mellitus Inadequate ControlAnxietyFatiguePain
IschaemiaManiaInsomniaTorsade De PointesDepressionFatigueDiarrhoeaDiarrhoea
NauseaAnxiety NecSuicide AttemptDepressionCompleted SuicidePainType 2 Diabetes MellitusSuicidal Ideation
Peritoneal EffusionAbnormal Behaviour NosEmotional DistressBlood Cholesterol IncreasedSuicidal IdeationBack PainVomitingCardio-respiratory Arrest
Metabolic AcidosisConfusional StateDepressionRespiratory ArrestBack PainWeight IncreasedFallAnxiety
PneumoniaCommunication DisorderHeadacheConstipationPainBlood Cholesterol IncreasedHeadacheBlood Glucose Increased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Wellbutrin and Trazodone?

You are not alone! Join a related mobile support group:
- support group for people who take Wellbutrin and Trazodone
- support group for people who take Trazodone Hydrochloride
- support group for people who take Wellbutrin

Can you answer these questions (Ask a question):

More questions for: Trazodone Hydrochloride, Wellbutrin

You may be interested at these reviews (Write a review):

  • Pain meds that cause insomnia
    I currently take 7.5 mg of Vicoprofen for pain for my Anklyosing Spondylitis. I have tried Vicodin and Norco previously, but nothing worked as well as the Vicoprofen. I have never had to up my dosage and I am still getting the same level of relief as I was when I first started it over a year and a half ago. I swear by the Vicoprofen and would recommend it to anyone who has any type of related pain, but, there is one downfall. Every time I take my pain meds I get a huge burst of energy. My pain is usually worst at night, so I have no choice but to take it before bed. More times than not it causes me to suffer extreme insomnia, which is no fun. Up until recently I just suffered through it. I went and saw my primary today and told her about the issues and she suggested I try Trazodone to help ease my mind so I can fall asleep easier and faster. I'm really hoping it works because I don't want to have to switch pain meds because they work so well, but I can't go much longer only getting 2-3 hours of sleep during the week.
    I will wrote another review in a week or so regarding my experience taking the Trazodone with the Vicoprofen.
  • Lamotrigine severe rash
    I started taking 100mg of Teva-Lamotrigine Nov 22 once daily. I got a refill on Dec 5 that was Mylan-Lamotrigine. Two days later I woke up with an odd hot feeling rash all over my body and severe fatigue. I went back to bed 1/2 hour later after taking my regular Wellbutrin and the Lamotrigine. I woke up late morning. It got progressively worse during the day and I had a headache,fever and chills. I took the anti-histimine Aerius later that day which didn't help. The next day I went to a walk in clinic and they said it wasn't the Lamotrigine and thought it was a virus and did a throat swab. The fever and chills went away after a few days but I still have the rash. Finally after a week I saw a doctor that agreed it was the drug and I am now on the second week of Prednisone steroid treatment and prescription Reactin which is helping slowly. I have reported it to the Mylan drug company.
  • Does paxil use cause lymphoma or other types of cancer
    I have been taking Paxil daily since 1997. For 14 years, I have had severe itching, a constant low grade fever with chills and night sweats. The itching is constant and so extreme that I scratch until the top layer of skin is gone, leaving a large area of scabs. The lymphoma tumors just appeared 6 weeks ago. I was also recently diagnosed with myeloma. I feel that Paxil may be to blame. I do not have a family history of cancer. I have been taking Trazodone at bedtime for 14 years also, which might also be a cause.
  • Do not take trazodone (2 responses)
    I trusted a dr who mr that trazodone as safe.inow am impotent . Ease do not prescribe t o men .
  • Intrsoccular pressure increase associated with wellbutrin
    I was given a prescription for Wellbutrin in approximately 1998. I had has my ocular pressure checked a year prior to this and it was okay. At the time, I only needed to wear reading glasses, common in people over 45. I took the drug at the full prescribed dosage for two weeks. Immediately prior to the narrow angle glaucoma episode, my vision had actually seemed to improve. For one day, prior, I could read without reading glasses. The following night, I was watching tv, and things suddenly became foggy. It was actually as if a fog had enveloped the room. I could not see anything except to discern between light and dark areas. I had to have emergency laser surgery the next morning. I mentioned to the doctor that Iwas taking Wellbutrin to stop smoking, and asked if it could have caused the ocular pressure increase. he consulted the PDR, and said there was no mention of it causing increases in ocular pressure. One year later my primary care doctor again insisted that I stop smoking, and again I mentioned that I thought it might increase ocular pressure. She told me to take a half dose, I did, and I took it one week, at which time I again experienced another episode of narrow angle glaucoma. When I go to the doctor's office my pressure in my left eye was 72, and 68 in my right eye. I was then referred on a triage basis to another doctor. I spent the rest of the day in his office having drops administered every fifteen minutes(extremely painful). I had extensive laser surgery the next morning.It required over fifty shots from the laser machine into each eye, (also extremely painful). I had lost considerable peripheral AND CENTRAL VISION in my left eye, and a good deal in my right. As a result of having to have such extensive laser surgery I also had cataracts that began at 50% maturity. I was advised by the surgeon that I should wait to have the cataracts removed "until my vision and quality of life was so poor that I was ready to commit suicide" because having the cataracts removed would cause the pressure in my eyes to become very difficult to control, and that more than likely I would end up being black blind. I would never use Wellbutrin under any circumstances, and I always check to make sure that any new meds I may be put on don't have anything to do with an increase in ocular pressure. If they do, I refuse to take them. The surgeon said he was surprised that I didn't lose more vision than I did, and I am grateful that I didn't, and that he was a good surgen. He wrote an article concerning this case for a medical journal since he said he had been seeing a recent increase of narrow angle glaucoma.

More reviews for: Trazodone Hydrochloride, Wellbutrin

Comments from related studies:

  • From this study (1 month ago):

  • Many autonomic nervous system symptoms with severe body pain and severe fatigue and gastrotestinal disruptions...

    Reply

  • From this study (4 months ago):

  • # 3 events over 21 days - chills, vomiting, diarrhea, sulfur smelling burps, reduced cognitive abilities approx. 7 days apart.

    Reply

  • From this study (4 months ago):

  • doc moc on Apr, 25, 2013:

    BREAK down FOOL!

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Wellbutrin (bupropion hydrochloride) is often used to treat depression. Trazodone Hydrochloride (trazodone hydrochloride) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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