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Review: Wellbutrin and Trazodone





Summary: drug interactions are reported among people who take Wellbutrin and Trazodone together.

This review analyzes the effectiveness and drug interactions between Wellbutrin and Trazodone. It is created by eHealthMe based on reports of 3,746 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Wellbutrin and Trazodone >>>

What are the drugs

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 54,972 users)

Trazodone hydrochloride has active ingredients of trazodone hydrochloride. It is often used in insomnia. (latest outcomes from Trazodone hydrochloride 6,611 users)

On Dec, 3, 2014: 3,746 people who take Wellbutrin, Trazodone Hydrochloride are studied

Wellbutrin, Trazodone Hydrochloride outcomes

Drug combinations in study:
- Wellbutrin (bupropion hydrochloride)
- Trazodone Hydrochloride (trazodone hydrochloride)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Wellbutrin is effective16.13%
(5 of 31 people)
34.48%
(20 of 58 people)
20.00%
(6 of 30 people)
40.00%
(18 of 45 people)
43.33%
(26 of 60 people)
58.33%
(28 of 48 people)
67.65%
(23 of 34 people)
16.67%
(1 of 6 people)
Trazodone Hydrochloride is effective38.71%
(12 of 31 people)
49.15%
(29 of 59 people)
34.38%
(11 of 32 people)
59.52%
(25 of 42 people)
53.03%
(35 of 66 people)
75.00%
(36 of 48 people)
62.07%
(18 of 29 people)
40.00%
(2 of 5 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
AnxietyDepressionType 2 Diabetes MellitusType 2 Diabetes MellitusDepressionType 2 Diabetes MellitusDiabetic RetinopathyDepression
DepressionInsomniaHysterectomyPainSuicidal IdeationDiabetes MellitusWeight IncreasedPain
TremorPainDiabetes MellitusHypertensionPainDepressionDiabetes Mellitus Inadequate ControlAnxiety
NauseaType 2 Diabetes MellitusBack PainWeight IncreasedAnxietyAnxietyProteinuriaDiabetes Mellitus
Drug IneffectiveHeadacheNauseaConvulsionWeight DecreasedBlood Triglycerides IncreasedBlood Glucose IncreasedNausea
Suicide AttemptAnxietyFungal InfectionPulmonary EmbolismSuicide AttemptObesityRenal DisorderType 2 Diabetes Mellitus
InsomniaBlood Cholesterol IncreasedInflammationAnxietyPancreatitisInsomniaDiabetic NeuropathyFatigue
DizzinessDiabetes MellitusGastric UlcerNauseaHallucinationSuicidal IdeationDiabetic Eye DiseaseWeight Increased
HyperglycaemiaFatigueHeadachePancreatitisTardive DyskinesiaNeoplasmInsomniaVomiting
FatigueCompleted SuicideBacterial InfectionFatigueConvulsionDry MouthTremorInsomnia

Drug effectiveness by gender :

FemaleMale
Wellbutrin is effective42.49%
(99 of 233 people)
36.00%
(27 of 75 people)
Trazodone Hydrochloride is effective57.81%
(137 of 237 people)
41.33%
(31 of 75 people)

Most common drug interactions by gender * :

FemaleMale
DepressionDepression
NauseaDiabetes Mellitus
AnxietyAnxiety
PainPain
Diabetes MellitusType 2 Diabetes Mellitus
Type 2 Diabetes MellitusInsomnia
FatigueFatigue
Weight IncreasedConstipation
DiarrhoeaBack Pain
HeadacheWeight Decreased

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Wellbutrin is effectiven/an/a16.67%
(2 of 12 people)
20.00%
(14 of 70 people)
21.28%
(20 of 94 people)
25.00%
(42 of 168 people)
22.14%
(29 of 131 people)
23.17%
(19 of 82 people)
Trazodone Hydrochloride is effectiven/an/a58.33%
(7 of 12 people)
31.67%
(19 of 60 people)
35.05%
(34 of 97 people)
28.48%
(43 of 151 people)
28.03%
(37 of 132 people)
33.33%
(28 of 84 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Type 2 Diabetes MellitusLethargyWeight IncreasedCompleted SuicideDiabetes MellitusDiabetes MellitusDepressionMyocardial Infarction
PancreatitisGruntingAnxietyCardiac ArrestType 2 Diabetes MellitusType 2 Diabetes MellitusPainDepression
Pancreatitis AcuteDysarthriaSuicidal IdeationType 2 Diabetes MellitusNauseaDepressionNauseaTremor
Pelvic Fluid CollectionRespiratory Rate IncreasedAggressionAnxietyWeight IncreasedNauseaAnxietyDrug Ineffective
Neuroleptic Malignant SyndromeDrug IneffectiveNauseaDiabetes MellitusDiabetes Mellitus Inadequate ControlAnxietyFatiguePain
IschaemiaManiaInsomniaTorsade De PointesDepressionFatigueDiarrhoeaDiarrhoea
NauseaAnxiety NecSuicide AttemptDepressionSuicidal IdeationPainType 2 Diabetes MellitusSuicidal Ideation
Peritoneal EffusionAbnormal Behaviour NosEmotional DistressBlood Cholesterol IncreasedCompleted SuicideBack PainVomitingCardio-respiratory Arrest
Metabolic AcidosisConfusional StateDepressionRespiratory ArrestBack PainWeight IncreasedFallAnxiety
PneumoniaCommunication DisorderHeadacheConstipationPainBlood Cholesterol IncreasedHeadacheBlood Glucose Increased

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Wellbutrin and Trazodone?

You are not alone! Join a related mobile support group:
- support group for people who take Wellbutrin and Trazodone
- support group for people who take Trazodone Hydrochloride
- support group for people who take Wellbutrin

Can you answer these questions (Ask a question):

  • I am on 2 x daily rifampin and 4 x daily cephalixin 500mg and and awake exhausted after 8-9 hours sleep and the fatigue is unbelievable all day every day, is this "normal" or should i investigate ore (1 answer)
    Had total knee replacement 11/12, bad from the start, knee swollen/hot/painful/unstable for most of 2 years before a mechanically successful Revision that found a loose patella and both ends of the prostheses loose. In spite of 10-12 aspirations and almost as many samples sent to labs for testing the result was always "no growth after a week". Following the revision, 10 days after, surgeons office called and says yes you have a staph E infection. Immediate therapy with 6 weeks of 3 X day IV PLUS 2 x per day oral Rifampin.
    IV over but now on the 2 X day Rifampin PLUS 4 X day 500mg cephalexin and the fatigue is unbelievable. Wake up exhausted after 8 hours sleep, daily hour plus mid afternoon naps.
  • I'm starting 7.5 mg remeron tonight , how can i expect to feal in the morning? (1 answer)
    Long period of depression desperate to find something that will work quik and give me some energy.
  • Has anyone been helped by taking lexapro and wellbutrin? (1 answer)
    I am the mom of a 22 year old who is trying to get through college and can't seem to find the right meds for depression. She is taking Lexapro and I am wondering if adding Wellbutrin will help.
  • Do you have issues snoring from testosterone
    I was in an IED explosion in Afghanistan, had a TRAUMATIC BRAIN INJURY, 2005.JULY 28THlevels were extremely low. my V.A. doctor put me on testesterone 2011 BREAST CANCER, AUG 11TH 2012 HIT AND RUN ON MY MOTORCYCLE. DUE TO all the pain meds chemo, etcetera. MY testosterone. At first it was the best thing that had happened to me since I woke up in the hospital now I snore like a drunk Marined. and the culprit is the testosterone. I need to save my marriage and do something aboot this. any ideas what I can do
  • Can long-term methadone use cause or increase the risk of colon cancer?
    I had a two-level spinal fusion at L4-S1 in 2000 after being injuried at work in Sept. 24, 1997. I lost everything after...the unjury, ability to do my job, my wife and family (couldn't take the strain) my home, my sense of self and purpose, direction and belonging...credit rating and ability to pay my bills.
    After a long period of waiting to settle my workmens' comp. case, I returned home, from the Bat Area back to Arizona to take of my mother with a yet un dianosed case of moderate dementia.
    Then, in 2011 I had a 2nd surgery to relieve spinal stenosis btwn. L2-L4, just above the fusion site.
    I've been taking methadone since early 2004, a little over ten years, now. I've had high blood pressure since my injury.

    Now, I waiting to be scheduled for a colonoscopy, with my father having had polyps and the way I've been feeling..drained, tired all the time, and stomach pains ( in addition to my chronic low back pain), I...
    find myself wondering if there is any relationtionship between the methadone and other meds and cancer?

More questions for: Trazodone Hydrochloride, Wellbutrin

You may be interested at these reviews (Write a review):

  • Intrsoccular pressure increase associated with wellbutrin
    I was given a prescription for Wellbutrin in approximately 1998. I had has my ocular pressure checked a year prior to this and it was okay. At the time, I only needed to wear reading glasses, common in people over 45. I took the drug at the full prescribed dosage for two weeks. Immediately prior to the narrow angle glaucoma episode, my vision had actually seemed to improve. For one day, prior, I could read without reading glasses. The following night, I was watching tv, and things suddenly became foggy. It was actually as if a fog had enveloped the room. I could not see anything except to discern between light and dark areas. I had to have emergency laser surgery the next morning. I mentioned to the doctor that Iwas taking Wellbutrin to stop smoking, and asked if it could have caused the ocular pressure increase. he consulted the PDR, and said there was no mention of it causing increases in ocular pressure. One year later my primary care doctor again insisted that I stop smoking, and again I mentioned that I thought it might increase ocular pressure. She told me to take a half dose, I did, and I took it one week, at which time I again experienced another episode of narrow angle glaucoma. When I go to the doctor's office my pressure in my left eye was 72, and 68 in my right eye. I was then referred on a triage basis to another doctor. I spent the rest of the day in his office having drops administered every fifteen minutes(extremely painful). I had extensive laser surgery the next morning.It required over fifty shots from the laser machine into each eye, (also extremely painful). I had lost considerable peripheral AND CENTRAL VISION in my left eye, and a good deal in my right. As a result of having to have such extensive laser surgery I also had cataracts that began at 50% maturity. I was advised by the surgeon that I should wait to have the cataracts removed "until my vision and quality of life was so poor that I was ready to commit suicide" because having the cataracts removed would cause the pressure in my eyes to become very difficult to control, and that more than likely I would end up being black blind. I would never use Wellbutrin under any circumstances, and I always check to make sure that any new meds I may be put on don't have anything to do with an increase in ocular pressure. If they do, I refuse to take them. The surgeon said he was surprised that I didn't lose more vision than I did, and I am grateful that I didn't, and that he was a good surgen. He wrote an article concerning this case for a medical journal since he said he had been seeing a recent increase of narrow angle glaucoma.
  • Librium 25mg and wellbutrin 300mg for >1 month
    I've been taking librium twice daily, morning and night, for about 3 months now along with wellbutrin XL in the morning. I've basically had the mood of "I don't care" and a great boost in confidence.
  • Bedwetting with paxil and wellbutrin
    I have been using both of these drugs and now have bedwetting issues 5 times a week on average. I would rate the bedwetting as moderate about a6/10 but my wife and I can live with this as she had made the comment " you are back to the man I married ". I started taking these due to depression about work and anxiety about work. We both think we can live with the bedwetting as no one needs to know about it
  • Wellbutrin caused my trigeminal neurlagia
    So I'm writing this to hopefully shed light to other users in the same position I was in. I had taken Wellbutrin for about 4 years. The pain experienced in my face was excruciatingly painful. It was just on one side of my face between my temple and upper lip. All the symptoms reflected Trigeminal Neuralgia. But even with an MRI nothing could be found. I suffered for 3 of those years with pain coming and going, not understanding what was going on. Finally one day I decided hell with Wellbutrin and just stopped taking it. It's been 6 months now and I have yet to have a single shred of pain. Coincidence? I doubt it.
  • Lorazepam nearly killed me during cancer treatment
    Day 31 of cold turkey and I want to die. It is a roller coaster from body tics and sweats to rage and crying in one day. I felt so good the 4h day of c/t. It was like before my cancer diagnosis. My bowels are better off Lorazepam. I threw up during bowel movements from the pain. Off Lorazepam first normal bowel movement in over 2 years. Stomach so damaged by Lorazepam that I have absolutely no appetite. I force myself to eat. Neuropathy in hands nearly gone. Feet are better but slower. Lymphedema that appeared after one year on Lorazepam is now gone. I have full range of motion.

More reviews for: Trazodone Hydrochloride, Wellbutrin

Comments from related studies:

  • From this study (1 month ago):

  • # 3 events over 21 days - chills, vomiting, diarrhea, sulfur smelling burps, reduced cognitive abilities approx. 7 days apart.

    Reply

  • From this study (1 month ago):

  • doc moc on Apr, 25, 2013:

    BREAK down FOOL!

    Reply

    Rhs on Oct, 13, 2012:

    Get your medical records
    and consult w/your doctor

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Wellbutrin (bupropion hydrochloride) is often used to treat depression. Trazodone Hydrochloride (trazodone hydrochloride) is often used to treat insomnia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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