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Review: Xalatan and Alphagan P

This review analyzes the effectiveness and drug interactions between Xalatan and Alphagan P. It is created by eHealthMe based on 1,335 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 4, 2014: 1,335 people who reported to have interactions when taking Xalatan, Alphagan P are studied

Trend of Xalatan, Alphagan P's drug interactions, side effects and effectiveness reports (5213916)

Drug combinations in study:
- Xalatan (latanoprost)
- Alphagan P (brimonidine tartrate)

eHealthMe real world results:

Most common interactions experienced by people in the use of Xalatan, Alphagan P:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)403
Asthenia (weakness)333
Intraocular Pressure Increased298
Glaucoma (increased fluid pressure in the eye with vision loss)295
Visual Acuity Reduced (reduced clearness of vision)248
Fatigue (feeling of tiredness)220
Drug Ineffective204
Eye Irritation188

Most common interactions experienced by people in long term use of Xalatan, Alphagan P:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Rash (redness)21
Intraocular Pressure Increased20
Dyspnoea (difficult or laboured respiration)15
Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)12
Tinnitus (a ringing in the ears)11
Drug Ineffective10
Corneal Thinning10
Ocular Hyperaemia (an abnormally large amount of blood in eye)10

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Alphagan P0.00%0.00%100.00%0.00%0.00%

Top conditions involved for these people * :

  1. Glaucoma
  2. Intraocular pressure increased
  3. Hypertension
  4. Open angle glaucoma
  5. Ill-defined disorder

Top co-used drugs for these people * :

  1. Cosopt
  2. Aspirin
  3. Trusopt
  4. Synthroid
  5. Timolol maleate

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Alphagan P, Xalatan

You can also:

Complete drug side effects:

On eHealthMe, Xalatan (latanoprost) is often used to treat glaucoma. Alphagan P (brimonidine tartrate) is often used to treat glaucoma. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (3 months ago):

  • My mom takes all three medications. Is this combination good? and does this cause her eyelids and lashes to form the crust?


  • From this study (3 months ago):

  • Bp has gone up to 142/71. Pulse is between 66 & 76. This has occurred since I started taking Meloxicam.


  • From this study (2 years ago):

  • I have developed tinnitus, hearing loss, neck pain, weakness, fatigue, cold sweats, fainting symptoms, loosing balance, swollen ankles, headaches


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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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- Alphagan P side effects
- Xalatan side effects



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