Review: taking Zetia and Synthroid together
Summary: drug interactions are reported among people who take Zetia and Synthroid together.
This review analyzes the effectiveness and drug interactions between Zetia and Synthroid. It is created by eHealthMe based on reports of 3,468 people who take the same drugs from FDA and social media, and is updated regularly.
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Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. (latest outcomes from 24,978 Zetia users) Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from 93,791 Synthroid users)
What are the drugs
Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. (latest outcomes from 24,978 Zetia users)
Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from 93,791 Synthroid users)
On Jan, 5, 2015: 3,468 people who take Zetia, Synthroid are studied
Drug combinations in study:
- Zetia (ezetimibe)
- Synthroid (levothyroxine sodium)
Drug effectiveness over time :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Zetia is effective||n/a||16.67%|
(1 of 6 people)
(1 of 3 people)
(6 of 15 people)
(8 of 21 people)
(7 of 16 people)
(3 of 4 people)
|Synthroid is effective||n/a||50.00%|
(1 of 2 people)
(3 of 3 people)
(3 of 8 people)
(7 of 14 people)
(13 of 21 people)
(18 of 22 people)
Most common drug interactions over time * :
|< 1 month||1 - 6 months||6 - 12 months||1 - 2 years||2 - 5 years||5 - 10 years||10+ years||not specified|
|Dizziness||Myalgia||Blood Creatine Phosphokinase Increased||Muscle Spasms||Bone Pain||Chronic Fatigue Syndrome||Fatigue||Nausea|
|Fatigue||Blood Creatine Phosphokinase Increased||Myalgia||Diverticulum||Pain In Extremity||Arteriosclerosis||Dizziness||Fatigue|
|Myalgia||Rhabdomyolysis||Nausea||Fatigue||Joint Swelling||Myalgia||Pulmonary Embolism||Dizziness|
|Nausea||Pelvic Pain||Fatigue||Muscular Weakness||Joint Range Of Motion Decreased||Parathyroid Tumour Benign||Deep Vein Thrombosis||Asthenia|
|Diarrhoea||Deep Vein Thrombosis||Headache||Cognitive Disorder||Burning Sensation||Haemorrhoids||Swollen Tongue||Dyspnoea|
|Pain In Extremity||Hepatic Failure||Thrombocytopenia||Hepatomegaly||Musculoskeletal Stiffness||Renal Disorder||Angioedema||Pain|
|Pruritus||Aspartate Aminotransferase Increased||Rhabdomyolysis||Anxiety||Gait Disturbance||Hypersomnia||Depression||Headache|
|Arthralgia||Back Pain||Jaundice Cholestatic||Myalgia||Nephrogenic Systemic Fibrosis||Osteopenia||Seizure||Arthralgia|
|Chest Pain||Diarrhoea||Abdominal Distension||Hypersensitivity||Peau D'orange||Nasal Turbinate Hypertrophy||Postnasal Drip||Depression|
|Pulmonary Embolism||Alanine Aminotransferase Increased||Abdominal Pain Upper||Headache||Oedema Peripheral||Hypothermia||Weight Increased||Back Pain|
Drug effectiveness by gender :
|Zetia is effective||38.64%|
(17 of 44 people)
(9 of 21 people)
|Synthroid is effective||69.39%|
(34 of 49 people)
(11 of 21 people)
Most common drug interactions by gender * :
|Asthenia||Renal Failure Acute|
|Back Pain||Cardiac Failure Congestive|
|Pain In Extremity||Anxiety|
Drug effectiveness by age :
|Zetia is effective||n/a||n/a||n/a||n/a||n/a||26.67%|
(4 of 15 people)
(10 of 59 people)
(12 of 42 people)
|Synthroid is effective||n/a||n/a||n/a||n/a||0.00%|
(0 of 1 people)
(6 of 15 people)
(19 of 63 people)
(20 of 43 people)
Most common drug interactions by age * :
|Type 2 Diabetes Mellitus||n/a||n/a||Cholecystitis Acute||Dyspnoea||Nausea||Nausea||Fatigue|
|Sensation Of Foreign Body||Gallbladder Non-functioning||Sleep Apnoea Syndrome||Pain||Depression||Dizziness|
|Gallbladder Operation||Anxiety||Anxiety||Completed Suicide||Headache||Nausea|
|Blood Cholesterol Increased||Pain||Asthenia||Nephrogenic Systemic Fibrosis||Pain||Asthenia|
|General Physical Health Deterioration||Blood Creatine Phosphokinase Increased||Vomiting||Dizziness||Arthralgia|
|Anhedonia||Deep Vein Thrombosis||Gait Disturbance||Abdominal Pain||Pain In Extremity|
|Balance Disorder||Nausea||Renal Failure Acute||Blood Glucose Increased||Back Pain|
* Some reports may have incomplete information.
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You are not alone! Join a related mobile support group:
- support group for people who take Zetia and Synthroid
- support group for people who take Synthroid
- support group for people who take Zetia
Can you answer these questions (Ask a question):
- I have an abnormal liver enzyme cyp2d6 and i am extremely sensitive to medications, are there any multivitamins/supplements that i can safely take?
I have abnormal cyp2d6 liver enzyme and have to take Tirosint thyroid medication because I react to binders in other thyroid medications. Are there any multivitamins/supplements that I can safely take?
- My daughter has congenital php and diabetes(hyperglycemia) not diagnosed until 18.with both...now 23...blood sugars are uncontrolled nothing so far is helping
All the patients I have chatted with have LOW blood sugar but mine is high. Nothing is helping it just keeps climbing. What gives?
- I took fexofenadine for a few months last year, and had oesophagus pain and problems swallowing. i had a gastroscopy eventually. but by the time i had the procedure, i had stopped the fexofenadine.
I had started the Oesophagus problems about the time I was put on Flexofenadine. I did not at the time blame this Ryhinitis drug to the digestion problems I was having. But stopped the Flezofenadine, as it did not completely help my Ryhinitis. I was put on Loretidine for the Ryhinitis, but this made me feel washed out, so after a couple,of months I changed to Benedryl with Acrivastine . My Oesophagus problems were starting to improve. Today 9 months later, Imwent to the doctor to see if there was anything else for Ryhinitis, I have been put back on Fexofenadine, worried now that my Oesophagus will start again to cause problems.
- Does ganderma promote hot flashes
I also use the Organo gold vitamins. It seems whenever I have a beverage of Organo Gold...I get hot flashes. Is there anybody else experiencing this outcome.?
- Does anyone take oral methotrexate and use topical magnesium chloride oil. if you do, do you have any side effects?
I would like to try the Magnesium Chloride topical oil, but because of the oral MTX, I was wondering if anyone was taking/using this combination and if there were any side effects to watch for.....
You may be interested at these reviews (Write a review):
- Syntroid and pruritus
I have been on levothyroxine for more than ten years and have had two episodes, each lasting over several months of unbearable itching. Doctors seem to deny any connection but are also unable identify the cause of the itching. None of the tests pick anything. Antihistamines are not much of a help. I am still in the throes of the second episode and life is plain, simple miserable.
- Thrush while on prograf
I am a health provider at an emergency room and had a patient come in because of a food bolus and when i examined his oral/pharynx I noticed he had thrush. Patient stated it has been their for a while. Patient also stated he has been having progressive difficulty in swallowing. Pt is a kidney transplant patient and has been worked up for other causes of his thrush (including HIV, as per patient results neg) and everything came back negative. I can only conclude that maybe the prograf which is a immunosupressent can possible be the cause
- Cardio version caused fingernail abnormalities
Right hip fracture. When prepping for surgery AFIB was found. Surgery was cancelled and they attempted to get AFIB under control. Finally, cardioversion was performed. When my nails started to grow out they all had two horizontal lines that cause the nail to break when it grows out to that point.
- Synthroid and breast enlargement
I have went from a B-C cup size to a D cup in the past 8-9 months.
- Double vision on levothyroxine
Diagnosed with under active thyroid in January 2011. Noticed onset of double vision in January 2014. Blurred vision and double vision worsened to such an extent that my glasses prescription has changed three times in less than 7 months. All the symptons I experience are a direct result of taking Levothyrixine and have increased as my dose has been increased.
Comments from related studies:
From this study (6 months ago):
From this study (7 months ago):
Night time Charley horses
I've been diagnosed with sero-negative rheumatoid arthritis. I have only tested minimally positive on the anti-CCP test and had a slightly high SED rate. My most recent tests showed some slight elevation in some RA marker tests, but nothing really significant. My rheumatologist is now doubting whether I have RA or some other pain syndrome going on.
IHateRA on Jul, 22, 2014:
My first RA Dr. put me on Plaquenil, it seemed to work for six months, then stopped - I thought the dose would be adjusted but it wasn't, so I went to another RA Doc - C-RP wasn't too high, sero neg. Was put on methotrexate - I ended up with a mouth sore the NEXT day, then bumps started appearing on my face, like zits, but NOT zits. I didn't touch them, but they ulcerated, left me full of scars on face, legs, etc - I have been OFF methotrexate for 5 years AND still have the same problem along with a daily fever (100+) and severe sweating - I knew the bumps were a sign of being allergic to Methotrexate, I quit it right away, called Dr. to get in - they told me 3 months (I was an established patient). In terms of fever and sweating, the ONLY thing I have in common with some of these posts and drug lists is METHOTREXATE - I wouldn't allow a pet to take it. I seem to have more in common with a friend who as MS - but my reg. doc doesn't listen to that. I can't take bio. drugs (live in "fungal" region), so I take pain medicine - as little as possible, I guess the Methotrexate is STILL messing with my body. I have a very good acupuncturist - when I told him that my Doc. wasn't "sure" about RA, he poked me (lightly) with his finger in two places and ask which hurt more. He confirmed the RA as it travels on certain meridians in Chinese medicine. Had I picked a different spot for hurting more, then we would have to figure out what I really had. My joints are deteriorating but now I'm afraid of the drugs for RA, so I just put up with and manage the pain (which is extreme) with pain meds, cold therapy (I love my cryo-cuff), and acupuncture. I wish that the side effects of RA drugs weren't as bad as they are! Leaving Cymbalta, Lyrica, Plaquenil and Methotrexate (all at different times) OUT of my body made me realize that they did affect me - I was "foggy" and sluggish mentally but didn't really notice it until I quit them.
Complete drug side effects:
On eHealthMe, Zetia (ezetimibe) is often used to treat high blood cholesterol. Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Zetia is used in:
- Synthroid is used in:
Other drugs that are used to treat the same conditions:
- Zetia alternatives:
- Synthroid alternatives:
NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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