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Review: Zetia and Synthroid

This review analyzes the effectiveness and drug interactions between Zetia and Synthroid. It is created by eHealthMe based on reports of 3,468 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: join a mobile support group for people who take Zetia and Synthroid >>>

What are the drugs

Zetia (what 24,962 Zetia users reported?) has active ingredients of ezetimibe. It is used in high blood cholesterol.

Synthroid (what 93,638 Synthroid users reported?) has active ingredients of levothyroxine sodium. It is used in hypothyroidism.

On Aug, 19, 2014: 3,468 people who take Zetia, Synthroid are studied

Zetia, Synthroid outcomes

Drug combinations in study:
- Zetia (ezetimibe)
- Synthroid (levothyroxine sodium)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Zetia is effectiven/a16.67%
(1 of 6 people)
33.33%
(1 of 3 people)
40.00%
(6 of 15 people)
38.10%
(8 of 21 people)
43.75%
(7 of 16 people)
75.00%
(3 of 4 people)
n/a
Synthroid is effectiven/a50.00%
(1 of 2 people)
100.00%
(3 of 3 people)
37.50%
(3 of 8 people)
50.00%
(7 of 14 people)
61.90%
(13 of 21 people)
81.82%
(18 of 22 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
DizzinessMyalgiaBlood Creatine Phosphokinase IncreasedMuscle SpasmsBone PainChronic Fatigue SyndromeFatigueNausea
FatigueBlood Creatine Phosphokinase IncreasedMyalgiaDiverticulumPain In ExtremityArteriosclerosisDizzinessFatigue
MyalgiaRhabdomyolysisNauseaFatigueJoint SwellingMyalgiaPulmonary EmbolismDizziness
NauseaPelvic PainFatigueMuscular WeaknessJoint Range Of Motion DecreasedParathyroid Tumour BenignDeep Vein ThrombosisAsthenia
DiarrhoeaDeep Vein ThrombosisHeadacheCognitive DisorderBurning SensationHaemorrhoidsSwollen TongueDyspnoea
Pain In ExtremityHepatic FailureThrombocytopeniaHepatomegalyMusculoskeletal StiffnessRenal DisorderAngioedemaPain
PruritusAspartate Aminotransferase IncreasedRhabdomyolysisAnxietyGait DisturbanceHypersomniaDepressionHeadache
ArthralgiaBack PainJaundice CholestaticMyalgiaNephrogenic Systemic FibrosisOsteopeniaSeizureArthralgia
Chest PainDiarrhoeaAbdominal DistensionHypersensitivityPeau D'orangeNasal Turbinate HypertrophyPostnasal DripDepression
Pulmonary EmbolismAlanine Aminotransferase IncreasedAbdominal Pain UpperHeadacheOedema PeripheralHypothermiaWeight IncreasedBack Pain

Drug effectiveness by gender :

FemaleMale
Zetia is effective38.64%
(17 of 44 people)
42.86%
(9 of 21 people)
Synthroid is effective69.39%
(34 of 49 people)
52.38%
(11 of 21 people)

Most common drug interactions by gender * :

FemaleMale
NauseaFatigue
FatigueAsthenia
DizzinessDizziness
PainDyspnoea
AstheniaRenal Failure Acute
DyspnoeaPneumonia
HeadacheOedema Peripheral
ArthralgiaNausea
Back PainCardiac Failure Congestive
Pain In ExtremityAnxiety

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Zetia is effectiven/an/an/an/an/a26.67%
(4 of 15 people)
16.95%
(10 of 59 people)
28.57%
(12 of 42 people)
Synthroid is effectiven/an/an/an/a0.00%
(0 of 1 people)
40.00%
(6 of 15 people)
30.16%
(19 of 63 people)
46.51%
(20 of 43 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Type 2 Diabetes Mellitusn/an/aCholecystitis AcuteDyspnoeaNauseaNauseaFatigue
Sensation Of Foreign BodyGallbladder Non-functioningSleep Apnoea SyndromePainDepressionDizziness
Gallbladder OperationAnxietyAnxietyCompleted SuicideHeadacheNausea
Blood Cholesterol IncreasedPainAstheniaNephrogenic Systemic FibrosisPainAsthenia
InjuryConvulsionHeadacheAstheniaDyspnoea
FatiguePeritonitisOedema PeripheralFatiguePain
General Physical Health DeteriorationBlood Creatine Phosphokinase IncreasedVomitingDizzinessArthralgia
AnhedoniaDeep Vein ThrombosisGait DisturbanceAbdominal PainPain In Extremity
Emotional DistressCellulitisDyspnoeaDyspnoeaHeadache
Balance DisorderNauseaRenal Failure AcuteBlood Glucose IncreasedBack Pain

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Zetia and Synthroid
- group for people who take Synthroid
- group for people who take Zetia

Comments from related studies:

  • From this study (6 days ago):

  • Night time Charley horses

    Reply

  • From this study (1 month ago):

  • I've been diagnosed with sero-negative rheumatoid arthritis. I have only tested minimally positive on the anti-CCP test and had a slightly high SED rate. My most recent tests showed some slight elevation in some RA marker tests, but nothing really significant. My rheumatologist is now doubting whether I have RA or some other pain syndrome going on.

    Reply

    IHateRA on Jul, 22, 2014:

    My first RA Dr. put me on Plaquenil, it seemed to work for six months, then stopped - I thought the dose would be adjusted but it wasn't, so I went to another RA Doc - C-RP wasn't too high, sero neg. Was put on methotrexate - I ended up with a mouth sore the NEXT day, then bumps started appearing on my face, like zits, but NOT zits. I didn't touch them, but they ulcerated, left me full of scars on face, legs, etc - I have been OFF methotrexate for 5 years AND still have the same problem along with a daily fever (100+) and severe sweating - I knew the bumps were a sign of being allergic to Methotrexate, I quit it right away, called Dr. to get in - they told me 3 months (I was an established patient). In terms of fever and sweating, the ONLY thing I have in common with some of these posts and drug lists is METHOTREXATE - I wouldn't allow a pet to take it. I seem to have more in common with a friend who as MS - but my reg. doc doesn't listen to that. I can't take bio. drugs (live in "fungal" region), so I take pain medicine - as little as possible, I guess the Methotrexate is STILL messing with my body. I have a very good acupuncturist - when I told him that my Doc. wasn't "sure" about RA, he poked me (lightly) with his finger in two places and ask which hurt more. He confirmed the RA as it travels on certain meridians in Chinese medicine. Had I picked a different spot for hurting more, then we would have to figure out what I really had. My joints are deteriorating but now I'm afraid of the drugs for RA, so I just put up with and manage the pain (which is extreme) with pain meds, cold therapy (I love my cryo-cuff), and acupuncture. I wish that the side effects of RA drugs weren't as bad as they are! Leaving Cymbalta, Lyrica, Plaquenil and Methotrexate (all at different times) OUT of my body made me realize that they did affect me - I was "foggy" and sluggish mentally but didn't really notice it until I quit them.

    Reply

  • From this study (7 months ago):

  • If I reduce the dose of Trazadone to 25mg from 50 mg, symptoms decrease but still persist.

    Reply

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More reviews for: Synthroid, Zetia

Complete drug side effects:

On eHealthMe, Zetia (ezetimibe) is often used to treat high blood cholesterol. Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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