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Review: taking Zofran and Hydroxyzine Pamoate together

Summary: drug interactions are reported among people who take Zofran and Hydroxyzine Pamoate together.

This review analyzes the effectiveness and drug interactions between Zofran and Hydroxyzine Pamoate. It is created by eHealthMe based on reports of 11 people who take the same drugs from FDA and social media, and is updated regularly.





You are not alone: join a mobile support group for people who take Zofran and Hydroxyzine Pamoate >>>

What are the drugs

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. (latest outcomes from 895 Zofran users)

Hydroxyzine pamoate has active ingredients of hydroxyzine pamoate. It is often used in stress and anxiety. (latest outcomes from 1,004 Hydroxyzine pamoate users)

On Feb, 24, 2015: 11 people who take Zofran, Hydroxyzine Pamoate are studied

Zofran, Hydroxyzine Pamoate outcomes

Drug combinations in study:
- Zofran (ondansetron hydrochloride)
- Hydroxyzine Pamoate (hydroxyzine pamoate)

Drug effectiveness over time :


Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Jugular Vein Thrombosisn/an/an/an/an/an/aNausea
Venoocclusive Liver DiseaseFebrile Neutropenia
ProctalgiaSecondary Immunodeficiency
DeliriumIntestinal Obstruction
HypomagnesaemiaRenal Failure Acute
Dry EyeBase Excess Decreased
Acute Myeloid Leukaemia RecurrentBlood Ph Increased
Oral PainAlopecia
Staphylococcal SepsisLactobacillus Infection

Drug effectiveness by gender :


Most common drug interactions by gender * :

Ventricular ExtrasystolesNausea
Torsade De PointesFebrile Neutropenia
Renal Tubular NecrosisRenal Failure Acute
Pseudomonas InfectionCirculatory Collapse
Blood Albumin DecreasedProctalgia
Blood Sodium DecreasedHypomagnesaemia
Haemoglobin DecreasedDiarrhoea
Haematocrit DecreasedEpigastric Discomfort
Nephropathy ToxicHypertension

Drug effectiveness by age :


Most common drug interactions by age * :

n/an/aRenal Tubular NecrosisHypokalaemiaRenal Failure Acuten/aNauseaBlood Albumin Decreased
Pseudomonas InfectionRenal Failure AcuteTachycardiaDry EyeSinoatrial Block
Nephropathy ToxicRenal Tubular NecrosisScleral HaemorrhageAcute Myeloid Leukaemia RecurrentBlood Sodium Decreased
Torsade De PointesTransaminases IncreasedAcute Respiratory Distress SyndromeVenoocclusive Liver DiseaseHaematocrit Decreased
Ventricular ExtrasystolesGamma-glutamyltransferase IncreasedAcute Respiratory FailureJugular Vein ThrombosisPneumonitis
Cytomegalovirus InfectionBlood Creatinine IncreasedBacterial SepsisRashHaemoglobin Decreased
Diabetes MellitusAspartate Aminotransferase IncreasedBlood Ph DecreasedPruritusRenal Failure Acute
Acute Graft Versus Host DiseaseAzotaemiaBlood Bicarbonate IncreasedStaphylococcal SepsisPancreatitis Necrotising
NauseaBlood Alkaline Phosphatase IncreasedFebrile NeutropeniaOral PainWhite Blood Cell Count Decreased
MalaiseAlanine Aminotransferase IncreasedAlopeciaHyperuricaemiaKeratitis Herpetic

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Zofran and Hydroxyzine Pamoate?

You are not alone! Join a related mobile support group:
- support group for people who take Zofran and Hydroxyzine Pamoate
- support group for people who take Hydroxyzine Pamoate
- support group for people who take Zofran

Can you answer these questions (Ask a question):

  • Can i take both zofran and melatonin at roughly the same time?
    Melatonin for GERD and sleep. Zofran for vomiting and nausea.
  • Can adolescent encopresis cause crohns disease in early twenties for a male?
    My son had encopresis until the age of 13. Now he's 22 and just been diagnosed with Crohn's disease. Could the many years of the encopresis have caused this?
  • Could the medication i am taking cause a side effect of aching testicles?
    I have suffered from severe anxiety disorder and social anxiety since i was 10 years old. about 1-1/2 years ago I started taking a drug called Hydroxyzine Pamoate {Generic for Vistaril} Since I have started taking the medication I have noticed that my anxiety symptoms have lessened but when i do experience anxiety i also experience Aching testicles which i assume is because of a lack of blood supply. I am at the point of stopping taking my medication because the situation is very uncomfortable. If anybody has advice or can help me in any way i would greatly appreciate it
  • Can you loose weight while taking hydroxyzine?
    Hydroxyzine has been my life saver but I have noticed a gradual increase in weight. My blood pressure has also gone up. I don't have the increased hunger but what scares me is I am not eating more than I normally do. I do not eat breakfast. I have a Glucerna at lunch and then dinner, protein potatoes/rice and veggies, sometimes pasta nothing huge and a snack at night. Maybe a small bowl of ice cream but not every night. I do not drink soda, lots of water and with dinner a large glass of apple juice. I have noticed every year I put on a little bit more weight. I was tested for my thyroid and it is normal. I haven't started an avid work out program. Doing high intense impact will not work due to my IC. I would like to try power walking. Anyone else experience any of these issues?
  • Is it safe to take zofran and magnesium citrate?
    Is it safe to take magnesium citrate for constipation and zofran?

More questions for: Hydroxyzine Pamoate, Zofran

You may be interested at these reviews (Write a review):

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  • I got pneumonia while taking topamax, obvious correlation
    I do not take all the medicines above all the time but I am using an implanted pump giving me less than 2mg of dilaudid per day, 75 mg effexor daily and usually buspar. Dr prescribed topamax within 4 days I was hospitalized with Pneumonia, stayed a week came home a week had a clear chest x ray and the next week I got it again and was hospitalized 9 days that time. I knew I had been on the med but could not remember the side effect that made me come off previously until i started it again 2 days ago and woke today with Pneumonia again. Last time my pulmonologist said that the med in combination with the antidepressant which is all I take right now relaxes me too much and it paralyzes my choking reflex causing aspiration of saliva and ultimately waking up sick as the bacteria laced fluid goes crazy in the moist conditions of the lungs.

More reviews for: Hydroxyzine Pamoate, Zofran

Complete drug side effects:

On eHealthMe, Zofran (ondansetron hydrochloride) is often used to treat nausea. Hydroxyzine Pamoate (hydroxyzine pamoate) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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