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Review: Zofran and Zantac

This review analyzes the effectiveness and drug interactions between Zofran and Zantac. It is created by eHealthMe based on 1,116 people who take the drugs. The review uses reports from FDA and social media, and is updated regularly.

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On Apr, 6, 2014: 1,116 people who reported to have interactions when taking Zofran, Zantac are studied

Trend of Zofran, Zantac's drug interactions, side effects and effectiveness reports (4746193)

Drug combinations in study:
- Zofran (ondansetron hydrochloride)
- Zantac (ranitidine hydrochloride)

eHealthMe real world results:

Most common interactions experienced by people in the use of Zofran, Zantac:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Vomiting497
Pyrexia (fever)409
Dyspnoea (difficult or laboured respiration)398
Diarrhoea380
Nausea (feeling of having an urge to vomit)370
Anxiety328
Pain307
Anaemia (lack of blood)238
Fatigue (feeling of tiredness)229
Dehydration (dryness resulting from the removal of water)214

Most common interactions experienced by people in long term use of Zofran, Zantac:

(click on each outcome to view in-depth analysis, incl. how people recovered)
InteractionNumber of reports
Diarrhoea12
Nausea (feeling of having an urge to vomit)10
Asthenia (weakness)6
Cardiac Arrest6
Cough6
Nephrogenic Systemic Fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)6
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)4
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)4
Oral Candidiasis (fungal infection of mouth)4
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)4

How effective are the drugs:

not at allsomewhatmoderatehighvery high
Zofran0.00%0.00%50.00%50.00%0.00%
Zantac0.00%0.00%0.00%0.00%100.00%

Top conditions involved for these people * :

  1. Premedication
  2. Nausea
  3. Breast cancer
  4. Pain
  5. Non-small cell lung cancer

Top co-used drugs for these people * :

  1. Dexamethasone
  2. Acetaminophen
  3. Metoclopramide
  4. Paclitaxel
  5. Lorazepam

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Zantac, Zofran

You can also:

Complete drug side effects:

On eHealthMe, Zofran (ondansetron hydrochloride) is often used to treat nausea. Zantac (ranitidine hydrochloride) is often used to treat gastroesophageal reflux disease. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

Comments from related studies:

  • From this study (4 months ago):

  • Symptoms have been going on for three years. Doctor's have done MRI's, CT's, Ultrasounds, and several lab test. They have yet to find any cause for the nausea, vomiting and dizziness. Only thing they have not tried is discontinuing some of the medicine.

    Reply

Can you answer these questions (what is this?):

More questions for: Zantac, Zofran

You may be interested at these reviews (what is this?):

  • Polyuria associated with zantac
    I was prescribed Zantac 150mg before breakfast and before dinner. After two days, I felt tired and had polyuria (by weight change 650 mL). I had kidney pain so drank water with a tiny bit of salt. Felt very nauseous, but more water helped. Continued to sip water til kidney pain eased. Have discontin ...

  • I got pneumonia while taking topamax, obvious correlation
    I do not take all the medicines above all the time but I am using an implanted pump giving me less than 2mg of dilaudid per day, 75 mg effexor daily and usually buspar. Dr prescribed topamax within 4 days I was hospitalized with Pneumonia, stayed a week came home a week had a clear chest x ray and ...

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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