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Review: Zoloft and Clozapine





Summary: drug interactions are reported among people who take Zoloft and Clozapine together.

This review analyzes the effectiveness and drug interactions between Zoloft and Clozapine. It is created by eHealthMe based on reports of 1,326 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone: join a mobile support group for people who take Zoloft and Clozapine >>>

What are the drugs

Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from Zoloft 78,283 users)

Clozapine has active ingredients of clozapine. It is often used in schizophrenia. (latest outcomes from Clozapine 21,922 users)

On Dec, 5, 2014: 1,326 people who take Zoloft, Clozapine are studied

Zoloft, Clozapine outcomes

Drug combinations in study:
- Zoloft (sertraline hydrochloride)
- Clozapine (clozapine)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Zoloft is effectiven/a0.00%
(0 of 2 people)
n/a0.00%
(0 of 2 people)
100.00%
(3 of 3 people)
50.00%
(2 of 4 people)
33.33%
(1 of 3 people)
n/a
Clozapine is effective0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
100.00%
(2 of 2 people)
0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
40.00%
(2 of 5 people)
66.67%
(2 of 3 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
TachycardiaGranulocytopeniaNeutropeniaType 2 Diabetes MellitusVomitingDrug DetoxificationPericardial EffusionDiabetes Mellitus
Lower Respiratory Tract InfectionConvulsionWhite Blood Cell Count DecreasedDeathWeight DecreasedFemur FractureType 2 Diabetes MellitusVomiting
Body Temperature IncreasedPyrexiaGeneral Physical Health DeteriorationDelusionLiver Function Test AbnormalDiabetic ComaRespiratory FailureWhite Blood Cell Count Decreased
C-reactive Protein IncreasedWhite Blood Cell Count DecreasedSeasonal AllergyGastrooesophageal Reflux DiseaseLoss Of ConsciousnessPelvic FractureDyspnoeaType 2 Diabetes Mellitus
FatigueLoss Of ConsciousnessSalivary HypersecretionObsessive-compulsive DisorderOverdosePneumoniaUnresponsive To StimuliTachycardia
PyrexiaHeart Rate IncreasedConfusional StatePancreatitis AcuteAlanine Aminotransferase IncreasedDiabetes MellitusBlood Triglycerides IncreasedDeath
Oxygen Saturation DecreasedSalivary HypersecretionDeathEmotional DistressHaemoglobin DecreasedMyocardial InfarctionAgitationNeutropenia
AsthmaAnxietyObsessive-compulsive DisorderFallMalaiseLeukopeniaCarbon Dioxide IncreasedWeight Decreased
Monocyte Count IncreasedMyoclonusAgranulocytosisDiabetes MellitusDiabetes MellitusLack Of Strength, Muscle Weakness, WeaknessMyocardial InfarctionWhite Blood Cell Count Increased
TachypnoeaObsessive-compulsive DisorderLeukopeniaConvulsionRectal HaemorrhageC-reactive Protein IncreasedAbscessLoss Of Consciousness

Drug effectiveness by gender :

FemaleMale
Zoloft is effective40.00%
(2 of 5 people)
44.44%
(4 of 9 people)
Clozapine is effective60.00%
(3 of 5 people)
44.44%
(4 of 9 people)

Most common drug interactions by gender * :

FemaleMale
VomitingDeath
Diabetes MellitusWhite Blood Cell Count Decreased
TachycardiaDiabetes Mellitus
White Blood Cell Count DecreasedWhite Blood Cell Count Increased
Type 2 Diabetes MellitusNeutropenia
Weight DecreasedPyrexia
Liver Function Test AbnormalType 2 Diabetes Mellitus
Haemoglobin DecreasedMyocardial Infarction
Loss Of ConsciousnessMalaise
Neutrophil Count DecreasedFall

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Zoloft is effectiven/an/a0.00%
(0 of 2 people)
0.00%
(0 of 4 people)
42.86%
(3 of 7 people)
28.57%
(2 of 7 people)
50.00%
(1 of 2 people)
n/a
Clozapine is effectiven/an/a0.00%
(0 of 2 people)
25.00%
(1 of 4 people)
42.86%
(3 of 7 people)
14.29%
(1 of 7 people)
100.00%
(2 of 2 people)
n/a

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
TremorConvulsionDrug IneffectiveVomitingDiabetes MellitusWhite Blood Cell Count DecreasedDeathDeath
Neoplasm MalignantTachycardiaWeight IncreasedOverdoseType 2 Diabetes MellitusType 2 Diabetes MellitusDiabetes MellitusPyrexia
Muscular WeaknessAnoxic EncephalopathyNeutropeniaLoss Of ConsciousnessDiabetic KetoacidosisDiabetes MellitusType 2 Diabetes MellitusMalaise
Cerebrovascular AccidentVomitingSedationWeight DecreasedNeutropeniaNeutropeniaLeukopeniaPneumonia
Loss Of ConsciousnessGeneral Physical Health DeteriorationLiver Function Test AbnormalWeight IncreasedPlatelet Count DecreasedGranulocytopeniaGranulocytopenia
HypoglycaemiaSinus BradycardiaAlanine Aminotransferase IncreasedAbdominal PainWhite Blood Cell Count IncreasedPneumoniaCough
Cardio-respiratory ArrestHypotensionTachycardiaConstipationNeutrophil Count DecreasedCardiac DisorderFatigue
Neutrophil Count DecreasedAggressionHaemoglobin DecreasedDyspnoeaTachycardiaAgranulocytosisDyspnoea
FatigueHypothermiaGranulocytopeniaObesityVomitingAnxietyDementia
CyanosisSomnolenceSedationPyrexiaLower Respiratory Tract InfectionCardiac ArrestInfluenza Like Illness

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Zoloft and Clozapine?

You are not alone! Join a related mobile support group:
- support group for people who take Zoloft and Clozapine
- support group for people who take Clozapine
- support group for people who take Zoloft

Recent conversations of related support groups:

Can you answer these questions (Ask a question):

More questions for: Clozapine, Zoloft

You may be interested at these reviews (Write a review):

  • Loss of menstruation
    Hi
    I stopped using setralin 50 µg in August 2014. (I have been taken it in 1 year for my PMS). After stopping taking the pills my period become very short in september and then desappeard. I got a funcional cyste (about 30 mm) and after 10-days treatment with progesterone I got my period in the end of oktober. Two weeks afterwards I got a spare bleeding and my gyn thought that it my be an ovulation bleeding. Anyhow I have not got my period yet. The samples taken in oktober showed low FSH and heigt E2. The doctor explained that it is posible that stopping setralin could cause this hormonal imbalance. I must say that my periods were not so regular for very long time like during that year with setralin but I had other side effects like problem with concentartion, nussea etc.
    For many years ago I was on Zoloft but I had not experienced the same problem. When I started the treatment this time they did not want to give me zoloft (because of the price). I had no choice but i experienced many symptoms from different generica of Setralin. I will meet my doctor om Monday again.
  • Soar throat after taking sertaline
    half a pill first timw. severe soar throat 2 hrs after taking 25mg
  • Miscarriage 6 weeks while on sertraline
    On sertraline 150 mg a day, alcohol (1+ drink a day) and high caffeine. Sertraline lowered to 100mg when 4.5 weeks pregnant, no alcohol no caffeine. Miscarried at 6 weeks.
  • Laryngitis and fluconazole
    Occasionally when I have a severe yeast infection, I get laryngitis. I am so thankful your article addresses this, as the doctors I have seen were less than receptive when I suggested a link. I do not have any of the other health concerns listed in the study, but am taking fluconazole.
  • Psychosis, weight loss and topamax (1 response)
    I had a brain hemorrhage in my occipital lobe. It left me with with a partial seizure disorder. The seizures would interrupt my ability to see. I was trying different anti-seizure medication and they all made me more tired and more depressed. My neurologist decided to try topamax. On topamax I began to feel more energetic and started losing weight. For the first time in years I woke up in the morning feeling zippy. I started feeling euphoric sometimes. I started to feel like I was glowing with life. I became so energetic I was like someone in a manic state. My temper got shorter and I began to hallucinate. I started to see angels and/or feel their presence. I live in a big city and there are a lot of people who are pretty mean here and I decided I wasn't going to let any of them push me around. I wasn't diplomatic anymore with anyone. Basically everyone thought I had gone crazy and I guess I had.
    My psychiatrist saw me and told my neurologist to "Get Her Off The Topamax!" After I stopped taking it and was more my normal tired self, my psychiatrist told me that I had been psychotic and that I had scared him. Unfortunately, after I stopped taking topamax I gained back the 30 pounds I had lost and none of my new clothes fit me. My doctors told me that they had never seen Topamax affect anyone the way it had affected me. They said it usually makes people more sedated. Hopefully, sharing my experience with Topamax will be helpful to someone.

More reviews for: Clozapine, Zoloft

Comments from related studies:

  • From this study (1 month ago):

  • doc moc on Apr, 25, 2013:

    BREAK down FOOL!

    Reply

    Rhs on Oct, 13, 2012:

    Get your medical records
    and consult w/your doctor

    Reply

    trust1983 on Dec, 3, 2012:

    Is it true in the states that a psych doc can up and just leave and refuse to treat you because you tried to kill yourself, especially if you didn't have a contact for life with you r doc?

    Reply

Post a new comment    OR    Read more comments

Complete drug side effects:

On eHealthMe, Zoloft (sertraline hydrochloride) is often used to treat depression. Clozapine (clozapine) is often used to treat schizophrenia. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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