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Review: Zoloft and Tylenol

This review analyzes the effectiveness and drug interactions between Zoloft and Tylenol. It is created by eHealthMe based on reports of 4,164 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: get help anytime and anywhere for people who take Zoloft and Tylenol >>>

What are the drugs

Zoloft (latest outcomes from 78,096 users) has active ingredients of sertraline hydrochloride. It is often used in depression.

Tylenol (latest outcomes from 55,588 users) has active ingredients of acetaminophen. It is often used in pain.

On Jul, 13, 2014: 4,164 people who take Zoloft, Tylenol are studied

Zoloft, Tylenol outcomes

Drug combinations in study:
- Zoloft (sertraline hydrochloride)
- Tylenol (acetaminophen)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Zoloft is effective0.00%
(0 of 8 people)
22.22%
(4 of 18 people)
0.00%
(0 of 5 people)
25.00%
(3 of 12 people)
53.33%
(8 of 15 people)
44.44%
(4 of 9 people)
80.00%
(4 of 5 people)
n/a
Tylenol is effective35.71%
(5 of 14 people)
50.00%
(2 of 4 people)
25.00%
(2 of 8 people)
16.67%
(1 of 6 people)
9.09%
(1 of 11 people)
62.50%
(5 of 8 people)
28.57%
(2 of 7 people)
0.00%
(0 of 2 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
NauseaDiarrhoeaDyspnoeaCerebral InfarctionMalnutritionPulmonary EmbolismNauseaNausea
SomnolencePulmonary EmbolismTremorHypercholesterolaemiaDepressionDiabetes MellitusChest PainPain
VomitingBack PainInfectionTemporomandibular Joint SyndromeHypothyroidismRestless Leg SyndromeSleep Apnoea SyndromeAnxiety
DysphagiaNauseaPancytopeniaRight Ventricular HypertrophyHeadacheChest DiscomfortThrombosisFatigue
Suicide AttemptAbdominal PainTachycardiaCardiac Failure CongestiveHypokalaemiaInsomniaDizzinessDepression
PainProduct Taste AbnormalRespiratory FailureTricuspid Valve IncompetencePruritusAlanine Aminotransferase IncreasedUterine LeiomyomaFall
AnxietyTremorFluid RetentionPatent Ductus ArteriosusSleep Apnoea SyndromeDeep Vein ThrombosisCardiac DisorderDyspnoea
MalaiseDyspnoeaVomitingVentricular Septal DefectFallAbortion SpontaneousCardiac Failure CongestiveBack Pain
PneumoniaFeeling AbnormalBrain AbscessAorta HypoplasiaHypernatraemiaCholelithiasisAngina PectorisAsthenia
MydriasisProduct Odour AbnormalCystitis HaemorrhagicCoarctation Of The AortaPainCholecystitis ChronicAbdominal PainHeadache

Drug effectiveness by gender :

FemaleMale
Zoloft is effective33.96%
(18 of 53 people)
26.32%
(5 of 19 people)
Tylenol is effective31.11%
(14 of 45 people)
26.67%
(4 of 15 people)

Most common drug interactions by gender * :

FemaleMale
NauseaPain
PainFatigue
AnxietyAnxiety
FatigueNausea
DepressionDepression
FallBack Pain
AstheniaDyspnoea
DiarrhoeaHeadache
DyspnoeaPneumonia
Oedema PeripheralDizziness

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Zoloft is effectiven/an/a0.00%
(0 of 5 people)
25.00%
(4 of 16 people)
12.50%
(4 of 32 people)
30.00%
(6 of 20 people)
12.12%
(4 of 33 people)
38.46%
(5 of 13 people)
Tylenol is effectiven/an/a16.67%
(1 of 6 people)
25.00%
(3 of 12 people)
18.75%
(6 of 32 people)
0.00%
(0 of 17 people)
18.75%
(6 of 32 people)
20.00%
(2 of 10 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
PancreatitisIntracranial Pressure IncreasedSuicide AttemptPainAnxietyNauseaPainNausea
Transposition Of The Great VesselsMaternal Exposure During PregnancyVomitingNauseaDepressionPainNauseaFall
Jaundice NeonatalSpeech DisorderSuicidal IdeationAnxietyNauseaFatigueAnxietyFatigue
Ileus ParalyticCraniosynostosisIrritable Bowel SyndromeDepressionType 2 Diabetes MellitusDepressionFatiguePain
ConvulsionPyrexiaDepressionFatigueAstheniaAnxietyDepressionAnxiety
Cleft PalateHypotensionBlood Triglycerides IncreasedPulmonary EmbolismHeadacheBack PainHeadachePneumonia
Heart Disease CongenitalMydriasisInflammatory Bowel DiseaseHeadachePainDiarrhoeaAnaemiaAsthenia
Atrial Septal DefectHeadachePainAbdominal Pain UpperDiabetes MellitusArthralgiaOedema PeripheralBack Pain
Patent Ductus ArteriosusCoughSkin HaemorrhageHypotensionGastrooesophageal Reflux DiseaseDyspnoeaAbdominal PainDepression
Infantile Apnoeic AttackNauseaAnxietyAstheniaFatiguePyrexiaDyspnoeaDyspnoea

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Zoloft and Tylenol
- group for people who take Tylenol
- group for people who take Zoloft

Comments from related studies:

  • From this study (7 days ago):

  • MRI scan showed chronic prolapsed disc and early signs of osteoporosis which they consider to be degenerative. I take 8 tramadol a day along side paracetamol
    As soon as the medication wears off I am in severe pain lethargy extreme tiredness and sometimes confusion. Ifeel as though my body has been taken over!
    I cannot stop sleeping When I wake I still feel extreme tiredness. Please help I feel that this has taken over my life and my husband fails to understand.This person I have become is not me at all!I know my body better than any doctor and it is not DEPRESSION as they would have me believe!!

    Reply

  • From this study (4 months ago):

  • Do not take Actifed (pills) if you're under alprazolam treatment, especially if you're having a high dosis of the benzodiazepine (or if you're being treated for a long time). The psychiatric effects can be devastating and your anxiety disorder and/or depression can get much worse.
    Unentencionally (due to a very stressfull event) I increased my alprazolam intake and since I had a flue I also started the Actifed pills 3 times a day. After two weeks in a regular basis of 7,5 mg of alprazolam + 3 actifed pills a day I got a major breakdown with completly psychotic behaviour, a huge rage attack, agressivity towards loved ones and a completly "out of me" speech and actions. Also I had suicidal behaviour tendencies, which I didn't have for almost 10 years (since I have diagnosed depression)!
    After being assisted at the hospital the attending doctor recommended the immediate suspension of alprazolam intake to avoid further similar episodes.

    Please do be very carefull with drug interactions since they can change your life in a glimpse. Be safe & take care!

    Reply

  • From this study (6 months ago):

  • I started my period withing this 24 hours.

    Reply

Post a new comment    OR    Read more comments

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Complete drug side effects:

On eHealthMe, Zoloft (sertraline hydrochloride) is often used to treat depression. Tylenol (acetaminophen) is often used to treat pain. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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