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Review: Zyprexa and Seroquel

This review analyzes the effectiveness and drug interactions between Zyprexa and Seroquel. It is created by eHealthMe based on reports of 7,734 people who take the same drugs from FDA and social media, and is updated regularly.

Stay connected: get help anytime and anywhere for people who take Zyprexa and Seroquel >>>

What are the drugs

Zyprexa (latest outcomes from 43,486 users) has active ingredients of olanzapine. It is often used in bipolar disorder.

Seroquel (latest outcomes from 78,993 users) has active ingredients of quetiapine fumarate. It is often used in bipolar disorder.

On Jul, 14, 2014: 7,734 people who take Zyprexa, Seroquel are studied

Zyprexa, Seroquel outcomes

Drug combinations in study:
- Zyprexa (olanzapine)
- Seroquel (quetiapine fumarate)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Zyprexa is effective12.50%
(1 of 8 people)
33.33%
(1 of 3 people)
66.67%
(2 of 3 people)
25.00%
(1 of 4 people)
25.00%
(1 of 4 people)
100.00%
(1 of 1 people)
100.00%
(1 of 1 people)
100.00%
(2 of 2 people)
Seroquel is effective0.00%
(0 of 2 people)
14.29%
(1 of 7 people)
n/a62.50%
(5 of 8 people)
25.00%
(1 of 4 people)
0.00%
(0 of 2 people)
0.00%
(0 of 2 people)
100.00%
(1 of 1 people)

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Type 2 Diabetes MellitusDiabetes MellitusDiabetes MellitusDiabetes MellitusDiabetes MellitusDiabetes MellitusType 2 Diabetes MellitusDiabetes Mellitus
Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusDiabetes MellitusType 2 Diabetes Mellitus
Blood Cholesterol IncreasedWeight IncreasedBlood Cholesterol IncreasedBlood Cholesterol IncreasedBlood Cholesterol IncreasedBlood Cholesterol IncreasedPancreatitisPancreatitis
HyperglycaemiaBlood Cholesterol IncreasedWeight IncreasedPancreatitisObesityObesityBlood Cholesterol IncreasedWeight Increased
PyrexiaPancreatitisPancreatitisDiabetic KetoacidosisPancreatitisPancreatitisObesityBlood Cholesterol Increased
Psychotic DisorderHyperglycaemiaObesityWeight IncreasedWeight IncreasedBlood Triglycerides IncreasedRenal Failure ChronicHyperglycaemia
Neuroleptic Malignant SyndromeBlood Triglycerides IncreasedHyperglycaemiaObesityBlood Triglycerides IncreasedHyperlipidaemiaConvulsionObesity
Blood Triglycerides IncreasedHyperlipidaemiaDiabetic KetoacidosisBlood Triglycerides IncreasedHyperglycaemiaHyperglycaemiaHyperlipidaemiaDiabetic Ketoacidosis
Weight IncreasedObesityHypertensionHyperglycaemiaHypertensionWeight IncreasedDiabetes Mellitus Inadequate ControlHypertension
HyperlipidaemiaDiabetic KetoacidosisBlood Triglycerides IncreasedHyperlipidaemiaHyperlipidaemiaDiabetic KetoacidosisDiabetic KetoacidosisBlood Triglycerides Increased

Drug effectiveness by gender :

FemaleMale
Zyprexa is effective50.00%
(6 of 12 people)
28.57%
(4 of 14 people)
Seroquel is effective46.15%
(6 of 13 people)
15.38%
(2 of 13 people)

Most common drug interactions by gender * :

FemaleMale
Diabetes MellitusDiabetes Mellitus
Type 2 Diabetes MellitusType 2 Diabetes Mellitus
PancreatitisPancreatitis
Weight IncreasedWeight Increased
Blood Cholesterol IncreasedBlood Cholesterol Increased
ObesityHyperglycaemia
HyperglycaemiaDiabetic Ketoacidosis
Diabetic KetoacidosisObesity
HypertensionHypertension
Blood Triglycerides IncreasedBlood Triglycerides Increased

Drug effectiveness by age :

0-12-910-1920-2930-3940-4950-5960+
Zyprexa is effectiven/a0.00%
(0 of 1 people)
0.00%
(0 of 3 people)
85.71%
(6 of 7 people)
0.00%
(0 of 3 people)
0.00%
(0 of 3 people)
27.27%
(3 of 11 people)
25.00%
(1 of 4 people)
Seroquel is effectiven/a0.00%
(0 of 1 people)
0.00%
(0 of 3 people)
71.43%
(5 of 7 people)
66.67%
(2 of 3 people)
0.00%
(0 of 6 people)
9.09%
(1 of 11 people)
0.00%
(0 of 3 people)

Most common drug interactions by age * :

0-12-910-1920-2930-3940-4950-5960+
Diabetes MellitusWeight IncreasedWeight IncreasedDiabetes MellitusDiabetes MellitusDiabetes MellitusDiabetes MellitusDiabetes Mellitus
PancreatitisAggressionDiabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes MellitusType 2 Diabetes Mellitus
Type 2 Diabetes MellitusConvulsionType 2 Diabetes MellitusWeight IncreasedBlood Cholesterol IncreasedBlood Cholesterol IncreasedPancreatitisWeight Increased
DeathTardive DyskinesiaAgitationBlood Cholesterol IncreasedObesityPancreatitisBlood Cholesterol IncreasedDeath
Diabetic KetoacidosisDizzinessAnxietyDiabetic KetoacidosisWeight IncreasedObesityWeight IncreasedAnxiety
Diabetic ComaDrug IneffectiveSuicidal IdeationSuicidal IdeationPancreatitisWeight IncreasedHyperglycaemiaConfusional State
HyperglycaemiaHyperglycaemiaDiabetic KetoacidosisPancreatitisHyperglycaemiaHyperglycaemiaDiabetic NeuropathyTremor
Blood Cholesterol IncreasedMetabolic DisorderAggressionObesityBlood Triglycerides IncreasedBlood Triglycerides IncreasedNeuropathy PeripheralHyperglycaemia
Pancreatitis AcuteDiabetes MellitusType 1 Diabetes MellitusHyperglycaemiaHypertensionDiabetes Mellitus Inadequate ControlObesityPyrexia
Weight IncreasedDyspnoeaAbnormal BehaviourPsychotic DisorderDiabetic KetoacidosisDiabetic KetoacidosisBlood Triglycerides IncreasedNeuroleptic Malignant Syndrome

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

Get connected! Join a mobile support group:
- group for people who take Zyprexa and Seroquel
- group for people who take Seroquel
- group for people who take Zyprexa

Comments from related studies:

  • From this study (6 months ago):

  • after taking these drugs I developed these disorders

    Reply

  • From this study (6 months ago):

  • after taking olanzapine for 2 months I developed anxiety. after taking olanzapine and Seroquel together for 2 years I developed peripheral neuropathy

    Reply

  • From this study (1 year ago):

  • over the last 5 to 6 yrs I've been on these drugs and other anti-depressants. also was in the hospital for close to 3 months 6 plus yrs ago. In the last 3 yrs my dental issues have gone from minor to severe. To where I now have rapid tooth decay. The V.A. which i am a veteran, doesn't cover dental, but would cover dental if it was a result of other treatment. i.e, Clonazepam, creon, folic acid, about 2 yrs with them prescribing seroquel and trying different anti-depressants, like zoloft and zyprexa for short (1 to 3 months) periods of time. And was wondering if any of these drugs could be the cause of me having to now have my teeth pulled and getting dentures?

    Reply

    Robert on Apr, 12, 2013:

    Zoloft is the most likely culprit, combined with clonazepam, together their similar oral side-effects combine in some cases causing oral and general dental problems. Zoloft's rather common side effect can be dry mouth.

    Clonazepam has properties making it a potent anti-convulsive drug, which are known to cause dental problems in some. It has been the cause of minor gum-soreness and bleeding, and with zoloft theres an interaction, because without saiva present in the mouth as a barrier, dental problems such as receding gum line, bleeding gums and enamel wear, all work to accelerate normal tooth decay, ultimately.

    These two meds have similarities that affect you and your mouth more than the average person. Nothing to worry about , there are dozens upon dozens of different benzos like clonazepam out there, ones with less potent anti seizure properties, and most docs don't even know much about them, yet they still make many of these rarely prescribed meds because of people just like you who could benefit from them.

    Reply

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Complete drug side effects:

On eHealthMe, Zyprexa (olanzapine) is often used to treat bipolar disorder. Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.

What is the drug used for and how effective is it:

Other drugs that are used to treat the same conditions:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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