Review: Zyprexa and Seroquel drug interactions
This review analyzes the interactions between Zyprexa and Seroquel. It is created by eHealthMe based on 7,711 people who have drug interactions while taking the drugs. The review uses reports from FDA and social media, and is updated regularly.
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What are the drugs
Zyprexa (latest outcomes from 43,463 users) has active ingredients of olanzapine. It is often used in bipolar disorder.
Seroquel (latest outcomes from 78,875 users) has active ingredients of quetiapine fumarate. It is often used in insomnia.
On Mar, 9, 2014: 7,711 people who reported to have interactions when taking Zyprexa, Seroquel are studied
Drug combinations in study:
- Zyprexa (olanzapine)
- Seroquel (quetiapine fumarate)
Most common interactions experienced by people in the use of Zyprexa, Seroquel:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)||6,377|
|Type 2 Diabetes Mellitus||4,364|
|Blood Cholesterol Increased||2,653|
|Blood Triglycerides Increased||2,317|
|Hyperglycaemia (high blood sugar)||1,383|
|Hypertension (high blood pressure)||1,344|
|Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)||1,134|
|Pancreatitis (inflammation of pancreas)||1,072|
|Obesity (a medical condition in which excess body fat)||724|
Most common interactions experienced by people in long term use of Zyprexa, Seroquel:(click on each outcome to view in-depth analysis, incl. how people recovered)
|Interaction||Number of reports|
|Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)||2,697|
|Type 2 Diabetes Mellitus||2,670|
|Blood Cholesterol Increased||1,698|
|Blood Triglycerides Increased||1,487|
|Hyperglycaemia (high blood sugar)||758|
|Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)||578|
|Pancreatitis (inflammation of pancreas)||524|
|Obesity (a medical condition in which excess body fat)||523|
|Hyperlipidaemia (presence of excess lipids in the blood)||286|
How effective are the drugs:
|not at all||somewhat||moderate||high||very high|
Top conditions involved for these people * :
- Bipolar disorder
- Sleep disorder
Top co-used drugs for these people * :
* Approximation only. Some reports may have incomplete information.
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Complete drug side effects:
On eHealthMe, Zyprexa (olanzapine) is often used to treat bipolar disorder. Seroquel (quetiapine fumarate) is often used to treat bipolar disorder. Find out below the conditions the drugs are used for, how effective they are, and any alternative drugs that you can use to treat those same conditions.
What is the drug used for and how effective is it:
- Zyprexa is used in:
- Seroquel is used in:
Other drugs that are used to treat the same conditions:
- Zyprexa alternatives:
- Seroquel alternatives:
Comments from related studies:
From this study (4 weeks ago):
From this study (4 weeks ago):
From this study (12 months ago):
after taking these drugs I developed these disorders
after taking olanzapine for 2 months I developed anxiety. after taking olanzapine and Seroquel together for 2 years I developed peripheral neuropathy
over the last 5 to 6 yrs I've been on these drugs and other anti-depressants. also was in the hospital for close to 3 months 6 plus yrs ago. In the last 3 yrs my dental issues have gone from minor to severe. To where I now have rapid tooth decay. The V.A. which i am a veteran, doesn't cover dental, but would cover dental if it was a result of other treatment. i.e, Clonazepam, creon, folic acid, about 2 yrs with them prescribing seroquel and trying different anti-depressants, like zoloft and zyprexa for short (1 to 3 months) periods of time. And was wondering if any of these drugs could be the cause of me having to now have my teeth pulled and getting dentures?
Robert on Apr, 12, 2013:
Zoloft is the most likely culprit, combined with clonazepam, together their similar oral side-effects combine in some cases causing oral and general dental problems. Zoloft's rather common side effect can be dry mouth.
Clonazepam has properties making it a potent anti-convulsive drug, which are known to cause dental problems in some. It has been the cause of minor gum-soreness and bleeding, and with zoloft theres an interaction, because without saiva present in the mouth as a barrier, dental problems such as receding gum line, bleeding gums and enamel wear, all work to accelerate normal tooth decay, ultimately.
These two meds have similarities that affect you and your mouth more than the average person. Nothing to worry about , there are dozens upon dozens of different benzos like clonazepam out there, ones with less potent anti seizure properties, and most docs don't even know much about them, yet they still make many of these rarely prescribed meds because of people just like you who could benefit from them.
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Trying to mitigate chorea movements in HD. Taking olanzapine 5mg/day, imipramite 25mg/day, pramipexol 0.50mg/day ,and biperid clorhydrate 2mg/day. Are these drugs compatible with each other. Paramipexol is more indicated for Parekinson Would it not be counterindicated for HD movements?
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I have Parkinson Disease diagnosed 4 years ago. It seems to be a slow developing PD since my symptoms have increased very little or nothing in all these years. I have a serious condition of insomnia, I get asleep very soon but awake many times during the night (6 or 7 times), I have been Rx sever ...
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Has been taking Zyprexa 2.5-5mg daily for 10 yrs.Developed metabolic syndrome and subsequently diabetes after 3 years on zyprexa.Has since tried multiple times but unsuccessfully to discontinue zyprexa.Apparent withdrawal sxs include severely depressed moods ,inability to get out of bed,severe weakn ...
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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