Allopurinol side effects - from FDA reports


Summary

In this review, we analyze Allopurinol side effects by the time on the drug, gender and age of the people who have side effects while taking Allopurinol. The review is based on 84,065 people who have side effects while taking the drug from FDA, and is updated regularly.

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Allopurinol

Allopurinol has active ingredients of allopurinol. It is often used in gout. (latest outcomes from Allopurinol 83,291 users)

On Jul, 22, 2017

84,065 people who take Allopurinol are studied.


Number of reports submitted per year:

Allopurinol side effects.

Most common side effects over time *:

< 1 month:
  • febrile neutropenia
  • pyrexia
  • toxic epidermal necrolysis
  • sepsis
  • thrombocytopenia
  • stevens-johnson syndrome
  • vomiting
  • rash
  • renal failure acute
  • pneumonia
1 - 6 months:
  • rash
  • stevens-johnson syndrome
  • febrile neutropenia
  • toxic epidermal necrolysis
  • white blood cell count decreased
  • sepsis
  • thrombocytopenia
  • vomiting
  • toxic skin eruption
  • pneumonia
6 - 12 months:
  • rash
  • pneumonia
  • thrombocytopenia
  • cervix carcinoma
  • vomiting
  • agranulocytosis
  • interstitial lung disease
  • sepsis
  • anaemia
  • aplastic anaemia
1 - 2 years:
  • diarrhoea
  • renal failure acute
  • international normalised ratio increased
  • anaemia
  • pyrexia
  • haemolytic anaemia
  • hypotension
  • platelet count decreased
  • renal impairment
  • sudden death
2 - 5 years:
  • thrombocytopenia
  • interstitial lung disease
  • bone marrow failure
  • renal impairment
  • upper gastrointestinal haemorrhage
  • platelet count decreased
  • pruritus
  • renal failure
  • renal failure acute
  • rhabdomyolysis
5 - 10 years:
  • renal impairment
  • interstitial lung disease
  • diarrhoea
  • renal failure acute
  • blood creatine phosphokinase increased
  • delirium
  • epistaxis
  • pleural effusion
  • pulmonary oedema
  • renal failure
10+ years:
  • pulmonary embolism
  • hypoxia
  • renal failure
  • weight decreased
  • adverse event
  • photosensitivity reaction
  • syncope
  • cerebral haemorrhage
  • leukopenia
  • pneumococcal sepsis
not specified:
  • vomiting
  • weight decreased
  • thrombocytopenia
  • death
  • white blood cell count decreased
  • renal failure acute
  • pyrexia
  • weight increased
  • pneumonia
  • renal failure

Most common side effects by gender *:

female:
  • vomiting
  • renal failure acute
  • weight decreased
  • white blood cell count decreased
  • thrombocytopenia
  • weight increased
  • pyrexia
  • renal failure
  • pneumonia
  • urinary tract infection
male:
  • weight decreased
  • thrombocytopenia
  • vomiting
  • death
  • pyrexia
  • white blood cell count decreased
  • renal failure acute
  • pneumonia
  • renal failure
  • rash

Most common side effects by age *:

0-1:
  • toxic epidermal necrolysis
  • premature baby
  • pyrexia
  • thrombocytosis
  • white blood cell count decreased
  • acute psychosis
  • dehydration
  • gastric ulcer haemorrhage
  • histiocytosis haematophagic
  • hypertonia
2-9:
  • tumour lysis syndrome
  • venoocclusive liver disease
  • white blood cell count decreased
  • febrile neutropenia
  • histiocytosis haematophagic
  • pyrexia
  • toxic epidermal necrolysis
  • vomiting
  • abdominal pain
  • anaemia
10-19:
  • venoocclusive liver disease
  • venoocclusive disease
  • white blood cell count decreased
  • tumour lysis syndrome
  • vomiting
  • febrile neutropenia
  • muscular weakness
  • pyrexia
  • septic shock
  • tachycardia
20-29:
  • white blood cell count decreased
  • vomiting
  • thrombocytopenia
  • weight decreased
  • pyrexia
  • tumour lysis syndrome
  • hepatosplenic t-cell lymphoma
  • rash
  • nausea
  • toxic epidermal necrolysis
30-39:
  • vomiting
  • pyrexia
  • stevens johnson syndrome
  • white blood cell count decreased
  • renal failure acute
  • anaemia
  • renal impairment
  • white blood cell count increased
  • thrombocytopenia
  • febrile neutropenia
40-49:
  • thrombocytopenia
  • vomiting
  • pyrexia
  • weight increased
  • weight decreased
  • white blood cell count decreased
  • renal failure acute
  • rhabdomyolysis
  • sepsis
  • toxic epidermal necrolysis
50-59:
  • vomiting
  • weight decreased
  • white blood cell count decreased
  • thrombocytopenia
  • weight increased
  • renal failure acute
  • rash
  • pyrexia
  • death
  • rhabdomyolysis
60+:
  • vomiting
  • weight decreased
  • thrombocytopenia
  • renal failure acute
  • pneumonia
  • white blood cell count decreased
  • pyrexia
  • renal failure
  • death
  • weight increased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Allopurinol (allopurinol) is often used to treat gout. Find out below the conditions the drugs are used for and how effective they are.

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