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From FDA reports: drug interactions between Xyrem, Actos, Glucotrol, Fluoxetine, Estradiol, Aygestin, Neurontin for a Female patient aged 43

This is a personalized study for a 43 year old female patient. The study is created by eHealthMe based on reports of 56 people who take the same drugs and have drug interactionsfrom FDA.

On Oct, 30, 2014: 56 people who reported to have interactions when taking Xyrem, Actos, Glucotrol, Fluoxetine, Estradiol, Aygestin, Neurontin are studied

Trend of Xyrem, Actos, Glucotrol, Fluoxetine, Estradiol, Aygestin, Neurontin's drug interactions, side effects, and effectiveness reports (668518)

Information of the patient in this study:

Age: 43

Gender: female

Conditions: Sleep Disorder

Drugs taking:
- Xyrem: used for < 1 month
- Actos
- Glucotrol
- Fluoxetine
- Estradiol
- Aygestin
- Neurontin

Drug interactions have: Anxiety, Fatigue, Heart Rate Increased, Heart Rate Irregular, Palpitations, Somnolence, Ventricular Extrasystoles

eHealthMe real world results:

Comparison with this patient's adverse outcomes among females aged 43 (±5):

InteractionNumber of reports
Anxiety4 (50.00%)
Fatigue (feeling of tiredness)6 (75.00%)
Heart Rate Increased2 (25.00%)
Heart Rate Irregular2 (25.00%)
Palpitations (feelings or sensations that your heart is pounding or racing)2 (25.00%)
Somnolence (a state of near-sleep, a strong desire for sleep)2 (25.00%)
Ventricular Extrasystoles (premature cardiac contraction)2 (25.00%)

Most common interactions experienced by females aged 43 (±5) in the use of Xyrem, Actos, Glucotrol, Fluoxetine, Estradiol, Aygestin, Neurontin:

InteractionNumber of reports
Anaemia (lack of blood)8
Muscle Spasms (muscle contraction)8
Sinusitis (inflammation of sinus)8
Urinary Tract Infection8
Haemorrhage (bleeding)8
Cerebrovascular Accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)8
Diabetic Neuropathy (neuropathic disorders that are associated with diabetes mellitus)8
Depression8
Coronary Artery Disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)8
Coma (state of unconsciousness lasting more than six hours)8

Most common interactions experienced by females aged 43 (±5) in long term use of Xyrem, Actos, Glucotrol, Fluoxetine, Estradiol, Aygestin, Neurontin:

InteractionNumber of reports
Abortion Spontaneous (naturally occurring miscarriage)1
Maternal Drugs Affecting Foetus (chemical affecting the baby before birth taken by mother)1
Pregnancy1

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Anxiety56 (100.00%)
Fatigue (feeling of tiredness)29 (51.79%)
Heart Rate Increased4 (7.14%)
Heart Rate Irregular2 (3.57%)
Palpitations (feelings or sensations that your heart is pounding or racing)14 (25.00%)
Somnolence (a state of near-sleep, a strong desire for sleep)4 (7.14%)
Ventricular Extrasystoles (premature cardiac contraction)16 (28.57%)

Most common interactions experienced by people in the use of Xyrem, Actos, Glucotrol, Fluoxetine, Estradiol, Aygestin, Neurontin:

InteractionNumber of reports
Anxiety56
Depression56
Pain56
Injury54
Intervertebral Disc Degeneration (spinal disc degeneration)54
Arthralgia (joint pain)52
Osteonecrosis Of Jaw (death of bone of jaw)50
Anhedonia (inability to experience pleasure from activities usually found enjoyable)50
Renal Failure (kidney dysfunction)46
Discomfort40

Most common interactions experienced by people in long term use of Xyrem, Actos, Glucotrol, Fluoxetine, Estradiol, Aygestin, Neurontin:

InteractionNumber of reports
Vertigo9
Anxiety9
Ventricular Extrasystoles (premature cardiac contraction)9
Therapeutic Procedure9
Synovial Cyst (cyst of joint filled with synovial fluid)9
Renal Failure (kidney dysfunction)9
Panic Attack9
Osteopenia (a condition where bone mineral density is lower than normal)9
Oedema Peripheral (superficial swelling)9
Proteinuria (presence of protein in the urine)9

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

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