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From FDA reports: drug interactions between Aleve, Synthroid, Centrum Silver

This is a study of Aleve, Synthroid, Centrum Silver drug interactions. The study is created by eHealthMe based on reports of 192 people who take the same drugs and have drug interactionsfrom FDA.

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On Jul, 8, 2014: 192 people who reported to have interactions when taking Aleve, Synthroid, Centrum Silver are studied

Trend of Aleve, Synthroid, Centrum Silver's drug interactions, side effects, and effectiveness reports (2432309)

Information of the patient in this study:

Gender: female

Conditions: Arthralgia

Drugs taking:
- Aleve
- Synthroid
- Centrum Silver

Drug interactions have: Allergy To Chemicals, Pruritus, Urticaria

eHealthMe real world results:

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Allergy To Chemicals2 (1.04%)
Pruritus (severe itching of the skin)21 (10.94%)
Urticaria (rash of round, red welts on the skin that itch intensely)2 (1.04%)

Most common interactions experienced by people in the use of Aleve, Synthroid, Centrum Silver:

InteractionNumber of reports
Dyspnoea (difficult or laboured respiration)45
Fatigue (feeling of tiredness)36
Arthralgia (joint pain)33
Contusion (a type of hematoma of tissue in which capillaries)29
Pneumonia29
Nausea (feeling of having an urge to vomit)26
Asthenia (weakness)25
Pain21
Fall18
Oedema Peripheral (superficial swelling)18

Most common interactions experienced by people in long term use of Aleve, Synthroid, Centrum Silver:

InteractionNumber of reports
Pain2
Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)2
Somnolence (a state of near-sleep, a strong desire for sleep)2
Myalgia (muscle pain)2
Thyroid Function Test Abnormal2
Circadian Rhythm Sleep Disorder (family of sleep disorders affecting, among other things, the timing of sleep)2
Overdose2
Sedation2
Loss Of Consciousness2

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (1 month ago):

  • Fatigue has been getting worse since 2009. CKD stage 3 diagnosed July 2014.

    Reply

  • From this study (1 month ago):

  • I've been diagnosed with sero-negative rheumatoid arthritis. I have only tested minimally positive on the anti-CCP test and had a slightly high SED rate. My most recent tests showed some slight elevation in some RA marker tests, but nothing really significant. My rheumatologist is now doubting whether I have RA or some other pain syndrome going on.

    Reply

    IHateRA on Jul, 22, 2014:

    My first RA Dr. put me on Plaquenil, it seemed to work for six months, then stopped - I thought the dose would be adjusted but it wasn't, so I went to another RA Doc - C-RP wasn't too high, sero neg. Was put on methotrexate - I ended up with a mouth sore the NEXT day, then bumps started appearing on my face, like zits, but NOT zits. I didn't touch them, but they ulcerated, left me full of scars on face, legs, etc - I have been OFF methotrexate for 5 years AND still have the same problem along with a daily fever (100+) and severe sweating - I knew the bumps were a sign of being allergic to Methotrexate, I quit it right away, called Dr. to get in - they told me 3 months (I was an established patient). In terms of fever and sweating, the ONLY thing I have in common with some of these posts and drug lists is METHOTREXATE - I wouldn't allow a pet to take it. I seem to have more in common with a friend who as MS - but my reg. doc doesn't listen to that. I can't take bio. drugs (live in "fungal" region), so I take pain medicine - as little as possible, I guess the Methotrexate is STILL messing with my body. I have a very good acupuncturist - when I told him that my Doc. wasn't "sure" about RA, he poked me (lightly) with his finger in two places and ask which hurt more. He confirmed the RA as it travels on certain meridians in Chinese medicine. Had I picked a different spot for hurting more, then we would have to figure out what I really had. My joints are deteriorating but now I'm afraid of the drugs for RA, so I just put up with and manage the pain (which is extreme) with pain meds, cold therapy (I love my cryo-cuff), and acupuncture. I wish that the side effects of RA drugs weren't as bad as they are! Leaving Cymbalta, Lyrica, Plaquenil and Methotrexate (all at different times) OUT of my body made me realize that they did affect me - I was "foggy" and sluggish mentally but didn't really notice it until I quit them.

    Reply

  • From this study (2 months ago):

  • I presented with Retinal Vein Occlusion for no apparent reason. I am 62, healthy, just had a checkup of body and eyes with no problems. Got off of HCTZ as a precaution. The vein opened back up after the occlusion, which the doctor said was a miracle. I'm in agreement with the "miracle" from God. I had this happen around the first of June, and no other problems with my eyes since. I have Salzman's Disease on my eyes. Have had for 3 years or so. No correlation to this occurance. Please let me know if you see anything that could have caused this. Thanks

    Reply

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