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What could cause Weakness, Pain, Transient Ischaemic Attack, Fatigue, Sudden Hearing Loss, Fungus Culture Positive, Muscle Cramps, Blurred vision, Tendonitis, Muscle pain for a 75-year old man who takes Amlodipine Besylate, Lisinopril, Crestor - 5MG?





Summary: 44 male patients aged 75 (±5) who take the same drugs are studied.

This is a personalized study for a 75 year old male patient who has Hypertension, High blood cholesterol and triglycerides. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Amlodipine besylate has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from Amlodipine besylate 19,065 users)

Lisinopril has active ingredients of lisinopril. It is often used in high blood pressure. (latest outcomes from Lisinopril 99,129 users)

What are the conditions

Hypertension (high blood pressure) can be treated by Lisinopril, Atenolol, Amlodipine Besylate, Diovan, Hydrochlorothiazide, Metoprolol Tartrate. (latest reports from Hypertension 351,152 patients)

High blood cholesterol and triglycerides can be treated by Lipitor, Simvastatin, Crestor, Pravastatin Sodium, Zocor, Atorvastatin Calcium. (latest reports from High Blood Cholesterol And Triglycerides 171,384 patients)

What are the symptoms

Weakness has been reported by people with multiple sclerosis, high blood pressure, high blood cholesterol, osteoporosis, pain.(latest reports from Weakness 180,407 patients)

Pain has been reported by people with osteoporosis, multiple sclerosis, birth control, rheumatoid arthritis, high blood cholesterol.(latest reports from Pain 291,941 patients)

Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)) has been reported by people with high blood pressure, diabetes, osteoporosis, arthritis, pain.(latest reports from Transient ischaemic attack 23,208 patients)

Fatigue (feeling of tiredness) has been reported by people with multiple sclerosis, high blood pressure, depression, rheumatoid arthritis, osteoporosis.(latest reports from Fatigue 200,583 patients)

Sudden hearing loss has been reported by people with high blood pressure, rheumatoid arthritis, osteoporosis, depression, high blood cholesterol.(latest reports from Sudden hearing loss 1,039 patients)

Fungus culture positive has been reported by people with pneumonia, rheumatoid arthritis, high blood pressure, ulcerative colitis, high blood cholesterol.(latest reports from Fungus culture positive 88 patients)

Mood Changes (latest reports from Mood Changes 115 patients)

Muscle cramps (painful sensations caused by muscle contraction) has been reported by people with osteoporosis, high blood cholesterol, high blood pressure, pain, depression.(latest reports from Muscle cramps 10,807 patients)

Vision Blurred has been reported by people with multiple sclerosis, high blood pressure, depression, pain, high blood cholesterol.(latest reports from Vision Blurred 48,523 patients)

Tendonitis (a condition that causes pain and swelling of tendons) has been reported by people with osteoporosis, sinusitis, high blood cholesterol, osteopenia, urinary tract infection.(latest reports from Tendonitis 9,548 patients)

Muscle pain (muscle pain) has been reported by people with high blood cholesterol, osteoporosis, high blood pressure, depression, multiple sclerosis.(latest reports from Muscle pain 73,416 patients)

On Dec, 22, 2014: 44 males aged 70 (±5) who take Amlodipine Besylate, Lisinopril, Crestor - 5MG are studied

Amlodipine Besylate, Lisinopril, Crestor - 5MG outcomes

Information of the patient in this study:

Age: 70

Gender: male

Conditions: High Bl, Hypertension, High blood cholesterol and triglycerides

Drugs taking:
- Amlodipine Besylate - EQ 10MG BASE (amlodipine besylate): used for 6 - 12 months
- Lisinopril - 5MG (lisinopril): used for 1 - 2 years
- Crestor - 5MG (rosuvastatin calcium): used for 1 - 6 months

Drug interactions have: moderate weakness, severe magnesium depleation, moderate pain, moderate transient ischaemic attack, moderate fatigue, moderate sudden hearing loss, moderate fungus culture positive, moderate lowered sex drive, moderate mood changes, severe muscle cramps, moderate vision blurred, moderate tendonitis, moderate muscle pain

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Weakness8 (18.18% of males aged 70 (±5) who take the drugs)
Magnesium Depleation2 (4.55% of males aged 70 (±5) who take the drugs)
Pain10 (22.73% of males aged 70 (±5) who take the drugs)
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))2 (4.55% of males aged 70 (±5) who take the drugs)
Fatigue (feeling of tiredness)9 (20.45% of males aged 70 (±5) who take the drugs)
Sudden Hearing Loss2 (4.55% of males aged 70 (±5) who take the drugs)
Fungus Culture Positive2 (4.55% of males aged 70 (±5) who take the drugs)
Lowered Sex Drive2 (4.55% of males aged 70 (±5) who take the drugs)
Mood Changes2 (4.55% of males aged 70 (±5) who take the drugs)
Muscle Cramps (painful sensations caused by muscle contraction)2 (4.55% of males aged 70 (±5) who take the drugs)
Vision Blurred2 (4.55% of males aged 70 (±5) who take the drugs)
Tendonitis (a condition that causes pain and swelling of tendons)2 (4.55% of males aged 70 (±5) who take the drugs)
Muscle Pain (muscle pain)3 (6.82% of males aged 70 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Weakness in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Weakness in Hypertension904 (3.87% of males aged 70 (±5) who have Hypertension)
Weakness in High Blood Cholesterol And Triglycerides924 (6.97% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Magnesium Depleation in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Magnesium Depleation in Hypertension1 (0.00% of males aged 70 (±5) who have Hypertension)
Magnesium Depleation in High Blood Cholesterol And Triglycerides1 (0.01% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Pain in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Pain in Hypertension368 (1.57% of males aged 70 (±5) who have Hypertension)
Pain in High Blood Cholesterol And Triglycerides395 (2.98% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Transient Ischaemic Attack in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Transient Ischaemic Attack in Hypertension134 (0.57% of males aged 70 (±5) who have Hypertension)
Transient Ischaemic Attack in High Blood Cholesterol And Triglycerides56 (0.42% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Fatigue in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Fatigue in Hypertension793 (3.39% of males aged 70 (±5) who have Hypertension)
Fatigue in High Blood Cholesterol And Triglycerides576 (4.35% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Sudden Hearing Loss in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Sudden Hearing Loss in Hypertension9 (0.04% of males aged 70 (±5) who have Hypertension)
Sudden Hearing Loss in High Blood Cholesterol And Triglycerides6 (0.05% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Fungus Culture Positive in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Fungus Culture Positive in Hypertension1 (0.00% of males aged 70 (±5) who have Hypertension)
Fungus Culture Positive in High Blood Cholesterol And Triglycerides1 (0.01% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Lowered Sex Drive in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Lowered Sex Drive in Hypertension1 (0.00% of males aged 70 (±5) who have Hypertension)
Lowered Sex Drive in High Blood Cholesterol And Triglycerides1 (0.01% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Mood Changes in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Mood Changes in Hypertension1 (0.00% of males aged 70 (±5) who have Hypertension)
Mood Changes in High Blood Cholesterol And Triglycerides1 (0.01% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Muscle Cramps in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Muscle Cramps in Hypertension30 (0.13% of males aged 70 (±5) who have Hypertension)
Muscle Cramps in High Blood Cholesterol And Triglycerides51 (0.38% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Vision Blurred in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Vision Blurred in Hypertension191 (0.82% of males aged 70 (±5) who have Hypertension)
Vision Blurred in High Blood Cholesterol And Triglycerides128 (0.97% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Tendonitis in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Tendonitis in Hypertension12 (0.05% of males aged 70 (±5) who have Hypertension)
Tendonitis in High Blood Cholesterol And Triglycerides29 (0.22% of males aged 70 (±5) who have High blood cholesterol and triglycerides)
Muscle Pain in High Bl1 (100.00% of males aged 70 (±5) who have High bl)
Muscle Pain in Hypertension341 (1.46% of males aged 70 (±5) who have Hypertension)
Muscle Pain in High Blood Cholesterol And Triglycerides923 (6.96% of males aged 70 (±5) who have High blood cholesterol and triglycerides)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Weakness in Amlodipine Besylate119 (4.79% of males aged 70 (±5) who take Amlodipine besylate)
Weakness in Lisinopril679 (5.81% of males aged 70 (±5) who take Lisinopril)
Magnesium Depleation in Amlodipine Besylate1 (0.04% of males aged 70 (±5) who take Amlodipine besylate)
Magnesium Depleation in Lisinopril1 (0.01% of males aged 70 (±5) who take Lisinopril)
Pain in Amlodipine Besylate55 (2.21% of males aged 70 (±5) who take Amlodipine besylate)
Pain in Lisinopril544 (4.66% of males aged 70 (±5) who take Lisinopril)
Transient Ischaemic Attack in Amlodipine Besylate17 (0.68% of males aged 70 (±5) who take Amlodipine besylate)
Transient Ischaemic Attack in Lisinopril79 (0.68% of males aged 70 (±5) who take Lisinopril)
Fatigue in Amlodipine Besylate102 (4.11% of males aged 70 (±5) who take Amlodipine besylate)
Fatigue in Lisinopril593 (5.08% of males aged 70 (±5) who take Lisinopril)
Sudden Hearing Loss in Amlodipine Besylate2 (0.08% of males aged 70 (±5) who take Amlodipine besylate)
Sudden Hearing Loss in Lisinopril1 (0.01% of males aged 70 (±5) who take Lisinopril)
Fungus Culture Positive in Amlodipine Besylate2 (0.08% of males aged 70 (±5) who take Amlodipine besylate)
Fungus Culture Positive in Lisinopril1 (0.01% of males aged 70 (±5) who take Lisinopril)
Lowered Sex Drive in Amlodipine Besylate1 (0.04% of males aged 70 (±5) who take Amlodipine besylate)
Lowered Sex Drive in Lisinopril1 (0.01% of males aged 70 (±5) who take Lisinopril)
Mood Changes in Amlodipine Besylate1 (0.04% of males aged 70 (±5) who take Amlodipine besylate)
Mood Changes in Lisinopril1 (0.01% of males aged 70 (±5) who take Lisinopril)
Muscle Cramps in Amlodipine Besylate8 (0.32% of males aged 70 (±5) who take Amlodipine besylate)
Muscle Cramps in Lisinopril20 (0.17% of males aged 70 (±5) who take Lisinopril)
Vision Blurred in Amlodipine Besylate22 (0.89% of males aged 70 (±5) who take Amlodipine besylate)
Vision Blurred in Lisinopril167 (1.43% of males aged 70 (±5) who take Lisinopril)
Tendonitis in Amlodipine Besylate3 (0.12% of males aged 70 (±5) who take Amlodipine besylate)
Tendonitis in Lisinopril12 (0.10% of males aged 70 (±5) who take Lisinopril)
Muscle Pain in Amlodipine Besylate49 (1.97% of males aged 70 (±5) who take Amlodipine besylate)
Muscle Pain in Lisinopril229 (1.96% of males aged 70 (±5) who take Lisinopril)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Amlodipine Besylate is effective0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
100.00%
(1 of 1 people)
n/an/a0.00%
(0 of 1 people)
n/an/a
Lisinopril is effectiven/an/an/a0.00%
(0 of 1 people)
n/a0.00%
(0 of 3 people)
n/an/a
Crestor - 5MG is effectiven/a100.00%
(1 of 1 people)
n/an/a100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
n/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Exhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)Fatigue (feeling of tiredness)Mood ChangesFungus Culture PositiveFaeces PaleErectile DysfunctionMusculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves)Atrial Fibrillation (fibrillation of the muscles of the atria of the heart)
Sudden Hearing LossFatigue (feeling of tiredness)Mood ChangesFatigue (feeling of tiredness)Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)Angioedema (rapid swelling of the dermis)Blood Pressure Increased
Fungus Culture PositiveTransient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))Sudden Hearing LossCoughImpaired MemoryLower Extremity Mass (mass in lower legs)Dizziness
Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))PainFatigue (feeling of tiredness)Sweating - Excessive (abnormally increased sweating)Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)Hyperlipidaemia (presence of excess lipids in the blood)
PainMuscle Cramps (painful sensations caused by muscle contraction)PainExhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)Sweating - Excessive (abnormally increased sweating)Sick Sinus Syndrome (a collection of heart rhythm disorders)
Muscle Pain (muscle pain)Vision BlurredTransient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))Fatigue (feeling of tiredness)Impaired MemoryWeight Decreased
WeaknessFungus Culture PositiveMuscle Cramps (painful sensations caused by muscle contraction)Lower Extremity Mass (mass in lower legs)Erectile DysfunctionSleep Apnoea Syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Vision BlurredWeaknessVision BlurredAngioedema (rapid swelling of the dermis)Contusion (a type of hematoma of tissue in which capillaries)
Faeces PaleMuscle Pain (muscle pain)Erectile DysfunctionCoughDelayed Sleep Phase
CoughTendonitis (a condition that causes pain and swelling of tendons)Impaired MemoryFaeces PaleBundle Branch Block Right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)

* Some reports may have incomplete information.

Comments for this study:

suhad Ghandour (2 years ago):

Female aged 67yrs, after starting Norvasc 5mg ,I started to suffer from muscle pain, knowing that I am taking Atacand plus and crestor 20 too. Is the pain caused by Norvasc alone,or due to this combination? I already did the CPK test and it was normal. please advise me what to do. Thank you in advance.
Reply the comment

Terry Ellis (3 years ago):

Correction to my earlier posting. The Norvasc did not cause erectile proglems.
Reply the comment

Terry Ellis (3 years ago):

Amlodipine Besylate definitely causes erectile problems!!!!! Is is not the same drug as Norvasc even though it claims to be the same. I took Norvasc for years with erectile problems, not to mention the headaches.
Reply the comment

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who have High Blood Cholesterol And Triglycerides
- support group for people who have Hypertension
- support group for people who have Fatigue
- support group for people who have Fungus Culture Positive
- support group for people who have Muscle Cramps
- support group for people who have Muscle Pain
- support group for people who have Pain
- support group for people who have Sudden Hearing Loss
- support group for people who have Tendonitis
- support group for people who have Transient Ischaemic Attack
- support group for people who have Vision Blurred
- support group for people who have Weakness
- support group for people who take Amlodipine Besylate
- support group for people who take Lisinopril

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