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From FDA reports: side effects of Articaine

This is a real world study of Articaine side effects. The study is created by eHealthMe based on 410 people who take the drug and have side effects.

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On Mar, 7, 2014: 410 people who reported to have side effects when taking Articaine are studied

Trend of Articaine's drug interactions, side effects, and effectiveness reports (2587121)

Information of the patient in this study:

Gender: male

Conditions: Tooth Repair

Drugs taking:
- Articaine: used for < 1 month

Side effects have: Hypoaesthesia, Nerve Injury, Pain, Tinnitus

eHealthMe real world results:

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

Side effectNumber of reports
Hypoaesthesia (reduced sense of touch or sensation)69 (16.83%)
Nerve Injury26 (6.34%)
Pain62 (15.12%)
Tinnitus (a ringing in the ears)2 (0.49%)

Most common side effects experienced by people in the use of Articaine:

Side effectNumber of reports
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)75
Hypoaesthesia (reduced sense of touch or sensation)69
Hypoaesthesia Oral (reduced sense of touch or sensation in mouth)68
Fatigue (feeling of tiredness)45
Chest Pain44
Bone Disorder44
Anaemia (lack of blood)43
Weight Decreased41

Most common side effects experienced by people in long term use of Articaine:


How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Hypoaesthesia, Nerve Injury, Pain, Tinnitus

You can also:

Comments from related studies:

  • From this study (6 days ago):

  • now daily seizures and having difficulty with walking. conditions are getting progressively worse.


  • From this study (7 months ago):

  • Every time I go to the dentist I have severe suicidal ideations.
    I suspect the Articaine Hydrochloride And Epinephrine Bitartrate (anesthesics)to be the cause by means of counter-indication with the rest of my medication.


  • From this study (1 year ago):

  • I would like feedback on any other anesthesia drugs that cause Vertigo and if this condition will improve.


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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Related conditions

- Nerve injury
- Pain
- Tinnitus


Related drug side effects

- Hypoaesthesia
- Nerve Injury
- Pain
- Tinnitus



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