A study of drug interactions between Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone for a Female patient aged 42
This is a personalized study of Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone drug interactions for a 42 year old female patient. The study is created by eHealthMe based on 17 reports from FDA.
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What are the drugs
Ceftriaxone has active ingredients of ceftriaxone sodium. It is used in pneumonia, infection, urinary tract infection, cellulitis, sepsis, fever.
Gentamicin has active ingredients of gentamicin sulfate. It is used in infection, preventive health care, endocarditis, sepsis, antibiotic, urinary tract infection.
Vancomycin hcl has active ingredients of vancomycin hydrochloride. It is used in infection.
Prednisone has active ingredients of prednisone. It is used in rheumatoid arthritis, asthma, inflammation, polymyalgia rheumatica, arthritis, systemic lupus erythematosus.
On Apr, 27, 2013: 17 people who reported to have interactions when taking Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone are studied

Information of the patient in this study:
Age: 42
Gender: female
Conditions: Alpha Haemolytic Streptococcal Infection, Epstein-barr Virus Infection
Drugs taking:
- Ceftriaxone
- Gentamicin
- Vancomycin Hcl
- Prednisone
Drug interactions have: Splenomegaly, Respiratory Distress, Endocarditis, Alpha Haemolytic Streptococcal Infection, Acute Myocardial Infarction
eHealthMe real world results:
For females aged 42 (±5):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Splenomegaly | 1 (20.00%) |
| Respiratory Distress | 1 (20.00%) |
| Endocarditis | 1 (20.00%) |
| Alpha Haemolytic Streptococcal Infection | 1 (20.00%) |
| Acute Myocardial Infarction | 1 (20.00%) |
Most common interactions experienced by females aged 42 (±5) in the use of Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Myalgia | 4 |
| 2 | Arthralgia | 4 |
| 3 | Drug Rash With Eosinophilia And Systemic Symptoms | 4 |
| 4 | Basedow's Disease | 4 |
| 5 | Human Herpes Virus 6 Serology Positive | 2 |
| 6 | Cytolytic Hepatitis | 2 |
| 7 | Human Herpesvirus 6 Infection | 2 |
| 8 | Renal Failure Acute | 2 |
| 9 | Endocarditis | 1 |
| 10 | Respiratory Distress | 1 |
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Most common interactions experienced by females aged 42 (±5) in long term use of Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone:
(click on each outcome to view in-depth analysis, incl. how people recovered)| None. |
For people in general (regardless of gender or age):
Comparison with this patient's adverse outcomes:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports |
| Splenomegaly | 1 (5.88%) |
| Respiratory Distress | 1 (5.88%) |
| Endocarditis | 1 (5.88%) |
| Alpha Haemolytic Streptococcal Infection | 1 (5.88%) |
| Acute Myocardial Infarction | 1 (5.88%) |
Most common interactions experienced by people in the use of Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Respiratory Failure | 10 |
| 2 | Acute Respiratory Distress Syndrome | 10 |
| 3 | Vomiting | 8 |
| 4 | Thrombocytopenia | 7 |
| 5 | Drug Rash With Eosinophilia And Systemic Symptoms | 6 |
| 6 | Basedow's Disease | 6 |
| 7 | Cardiac Failure | 5 |
| 8 | Peritonitis | 5 |
| 9 | Pneumothorax | 5 |
| 10 | Hepatocellular Injury | 5 |
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Most common interactions experienced by people in long term use of Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone:
(click on each outcome to view in-depth analysis, incl. how people recovered)| Interaction | Number of reports | |
| 1 | Acute Respiratory Distress Syndrome | 3 |
| 2 | Respiratory Failure | 3 |
| 3 | Pneumothorax | 3 |
| 4 | Peritonitis | 3 |
| 5 | Cardiac Failure | 3 |
| 6 | Thrombocytopenia | 3 |
| 7 | Hepatocellular Injury | 3 |
| 8 | Diarrhoea | 2 |
| 9 | Abdominal Pain | 1 |
| 10 | Blood Disorder | 1 |
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In-depth study of side effects (who have it, when it happens and how):
- Splenomegaly in Ceftriaxone (20 reports)
- Splenomegaly in Gentamicin (25 reports)
- Splenomegaly in Vancomycin Hcl (5 reports)
- Splenomegaly in Prednisone (537 reports)
- Respiratory Distress in Ceftriaxone (96 reports)
- Respiratory Distress in Gentamicin (108 reports)
- Respiratory Distress in Vancomycin Hcl (34 reports)
- Respiratory Distress in Prednisone (990 reports)
- Endocarditis in Ceftriaxone (21 reports)
- Endocarditis in Gentamicin (78 reports)
- Endocarditis in Vancomycin Hcl (11 reports)
- Endocarditis in Prednisone (171 reports)
- Alpha Haemolytic Streptococcal Infection in Ceftriaxone (3 reports)
- Alpha Haemolytic Streptococcal Infection in Gentamicin (4 reports)
- Alpha Haemolytic Streptococcal Infection in Vancomycin Hcl (3 reports)
- Alpha Haemolytic Streptococcal Infection in Prednisone (84 reports)
- Acute Myocardial Infarction in Ceftriaxone (21 reports)
- Acute Myocardial Infarction in Gentamicin (22 reports)
- Acute Myocardial Infarction in Vancomycin Hcl (5 reports)
- Acute Myocardial Infarction in Prednisone (408 reports)
Could it be a symptom from a condition:
- Splenomegaly in Alpha Haemolytic Streptococcal Infection
- Splenomegaly in Epstein-barr Virus Infection
- Respiratory Distress in Alpha Haemolytic Streptococcal Infection
- Respiratory Distress in Epstein-barr Virus Infection
- Endocarditis in Alpha Haemolytic Streptococcal Infection
- Endocarditis in Epstein-barr Virus Infection
- Alpha Haemolytic Streptococcal Infection in Alpha Haemolytic Streptococcal Infection
- Alpha Haemolytic Streptococcal Infection in Epstein-barr Virus Infection
- Acute Myocardial Infarction in Alpha Haemolytic Streptococcal Infection
- Acute Myocardial Infarction in Epstein-barr Virus Infection
Related drug interactions:
- Prednisone and Vancomycin Hcl drug interactions (1,524 reports)
- Prednisone and Gentamicin drug interactions (383 reports)
- Prednisone and Ceftriaxone drug interactions (920 reports)
Comments from related studies:
From this study (3 months ago):
From this study (3 months ago):
The patient is complaining of skin bluish dicoloration with blue staining over her bed sheets after 7days of administration
Have been on all of the above drugs for some time, however just began the itching within the last couple of days.
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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.
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