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From FDA reports: drug interactions between Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone for a Female patient aged 42

This is a personalized study for a 42 year old female patient. The study is created by eHealthMe based on reports of 20 people who take the same drugs and have drug interactionsfrom FDA.

On Feb, 28, 2015: 20 people who reported to have interactions when taking Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone are studied

Trend of Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone's drug interactions, side effects, and effectiveness reports (3087507)

Information of the patient in this study:

Age: 42

Gender: female

Conditions: Alpha Haemolytic Streptococcal Infection, Epstein-barr Virus Infection

Drugs taking:
- Ceftriaxone
- Gentamicin
- Vancomycin Hcl
- Prednisone

Drug interactions have: Splenomegaly, Respiratory Distress, Endocarditis, Alpha Haemolytic Streptococcal Infection, Acute Myocardial Infarction

eHealthMe real world results:

Comparison with this patient's adverse outcomes among females aged 42 (±5):

InteractionNumber of reports
Splenomegaly (enlargement of spleen)2 (40.00%)
Respiratory Distress (difficulty in breathing)2 (40.00%)
Endocarditis (inflammation in heart muscle)2 (40.00%)
Alpha Haemolytic Streptococcal Infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)2 (40.00%)
Acute Myocardial Infarction (acute heart attack)2 (40.00%)

Most common interactions experienced by females aged 42 (±5) in the use of Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone:

InteractionNumber of reports
Drug Rash With Eosinophilia And Systemic Symptoms (adverse drug reactions with rash)5
Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)5
Cytolytic Hepatitis (dissolution or destruction of a liver cell)5
Human Herpesvirus 6 Infection5
Myalgia (muscle pain)5
Human Herpes Virus 6 Serology Positive5
Renal Failure Acute (rapid kidney dysfunction)5
Arthralgia (joint pain)5
Endocarditis (inflammation in heart muscle)2
Respiratory Distress (difficulty in breathing)2

Most common interactions experienced by females aged 42 (±5) in long term use of Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone:

None.

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
Splenomegaly (enlargement of spleen)2 (10.00%)
Respiratory Distress (difficulty in breathing)2 (10.00%)
Endocarditis (inflammation in heart muscle)2 (10.00%)
Alpha Haemolytic Streptococcal Infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)2 (10.00%)
Acute Myocardial Infarction (acute heart attack)2 (10.00%)

Most common interactions experienced by people in the use of Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone:

InteractionNumber of reports
Drug Rash With Eosinophilia And Systemic Symptoms (adverse drug reactions with rash)20
Basedow's Disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)20
Thrombocytopenia (decrease of platelets in blood)16
Human Herpes Virus 6 Serology Positive16
Rash (redness)16
Arthralgia (joint pain)14
Hepatocellular Injury (liver injury)10
Acute Respiratory Distress Syndrome (sudden failure of the respiratory (breathing) system)10
Cardiac Failure10
Respiratory Failure (inadequate gas exchange by the respiratory system)10

Most common interactions experienced by people in long term use of Ceftriaxone, Gentamicin, Vancomycin Hcl, Prednisone:

InteractionNumber of reports
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)3
Respiratory Failure (inadequate gas exchange by the respiratory system)3
Acute Respiratory Distress Syndrome (sudden failure of the respiratory (breathing) system)3
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)3
Cardiac Failure3
Thrombocytopenia (decrease of platelets in blood)3
Hepatocellular Injury (liver injury)3
Abdominal Pain2
Diarrhoea2
Blood Disorder2

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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Comments from related studies:

  • From this study (2 months ago):

  • I have had C-diff since 9/3 2014. I am on my 5th reoccurrence of it, and I took flagyl twice and vancomyacin with the secondary medication. no relief. Ended in the hospital with dehydration, lack of potassium and felt horrible.
    My moods, have been up and down, since I just came down with a bladder infection two weeks before my fecal transplant and it took them a week to give me the antibiotics. They gave me bacteria, and all of the sudden on the 4th day my knees hurt, my upper thighs. I do wonder what is wrong. I have always been a very compliant do not complain patient but gosh, I feel like I am going to die.
    I do not know how I can continue to work?

    Reply

  • From this study (1 year ago):

  • Developed symptoms of hyperventation syndrome (need to take frequent deep satisfying deep breaths- not rapid breathing) after hospital stay for flu and possible meningitis. My chest x ray and CBC is normal. One doc tried to tell me this was PTSD/anxiety from post hospitalization. It is not. I am not anxious except for fact that I cannot breath right. I do not have pneumonia. I have never had this before, but I'm even short of breath while talking to people and distracted - still needing to take deep breaths mid conversation. I have never had some of the above drugs before and wondered if they could have anything to do with it. Thank you.

    Reply

    srandall on Mar, 13, 2014:

    I am a Caucasian female age 42. On vanco 3rd time for 3weeks this time. First week this time can't breathe normally, stays n cat scan clear, ringing, popping in ears n loss of hearing, frequent urination and way more urine volume. Dr Denys any of these symptoms from vanco as he gives lectures on vanco. I also had kidney function decreases n he says he would prescribe even if kidneys in half failure because vanco is the best! Sending him documents from Mayo saying after 10 days on vanco patients need to be monitored for hearing, kidney and shallow breathing. Maybe he can add to his lectures.

    Reply

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Can you answer these questions (Ask a question):

More questions for: Acute Myocardial Infarction, Alpha Haemolytic Streptococcal Infection, Ceftriaxone, Endocarditis, Epstein-barr Virus Infection, Gentamicin, Prednisone, Respiratory Distress, Splenomegaly, Vancomycin Hcl

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In-depth study of side effects (who have it, when it happens and how):

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