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What could cause Restlessness, Insomnia, Restless Leg Syndrome for a 33-year old man who takes Lithium Carbonate, Cymbalta, Abilify, Trihexyphenidyl Hydrochloride, Benadryl, Aspirin, Wellbutrin?





Summary: 3 male patients aged 33 (±5) who take the same drugs are studied.

This is a personalized study for a 33 year old male patient who has Bipolar Disorder, Depression, Restlessness, Insomnia, Neck Pain, Addiction. The study is created by eHealthMe based on reports from FDA and social media.

What are the drugs

Lithium carbonate has active ingredients of lithium carbonate. It is often used in bipolar disorder. (latest outcomes from Lithium carbonate 16,053 users)

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 49,275 users)

Abilify has active ingredients of aripiprazole. It is often used in depression. (latest outcomes from Abilify 30,166 users)

Trihexyphenidyl Hydrochloride has active ingredients of trihexyphenidyl hydrochloride. It is often used in parkinson's disease. (latest outcomes from Trihexyphenidyl Hydrochloride 371 users)

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from Benadryl 29,367 users)

Aspirin has active ingredients of aspirin. It is often used in blood clots. (latest outcomes from Aspirin 164,508 users)

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 54,972 users)

What are the conditions

Bipolar disorder (mood disorder) can be treated by Lamictal, Lithium Carbonate, Seroquel, Abilify, Lamotrigine, Depakote. (latest reports from Bipolar Disorder 43,640 patients)

Depression can be treated by Zoloft, Cymbalta, Prozac, Wellbutrin Xl, Celexa, Lexapro. (latest reports from Depression 254,062 patients)

Restlessness (not able to rest) can be treated by Mirapex, Requip, Ativan, Seroquel, Ropinirole Hydrochloride, Clonazepam. (latest reports from Restlessness 54,495 patients)

Insomnia (sleeplessness) can be treated by Ambien, Trazodone Hydrochloride, Lunesta, Zolpidem Tartrate, Ambien Cr, Zopiclone. (latest reports from Insomnia 135,811 patients)

Neck pain can be treated by Ibuprofen, Flexeril, Cyclobenzaprine Hydrochloride, Gabapentin, Percocet, Meloxicam. (latest reports from Neck Pain 23,791 patients)

Addiction can be treated by Suboxone, Methadone Hydrochloride, Subutex, Methadose, Methamphetamine Hydrochloride, Nicotine. (latest reports from Addiction 441 patients)

What are the symptoms

Restlessness (not able to rest) has been reported by people with depression, quit smoking, pain, stress and anxiety, high blood pressure.(latest reports from Restlessness 54,495 patients)

Insomnia has been reported by people with depression, quit smoking, high blood pressure, pain, stress and anxiety.(latest reports from Insomnia 135,811 patients)

Restless leg syndrome (a powerful urge to move your legs) has been reported by people with osteoporosis, depression, high blood pressure, pain, stress and anxiety.(latest reports from Restless leg syndrome 16,008 patients)

On Dec, 18, 2014: 3 males aged 28 (±5) who take Lithium Carbonate, Cymbalta, Abilify, Trihexyphenidyl Hydrochloride, Benadryl, Aspirin, Wellbutrin are studied

Lithium Carbonate, Cymbalta, Abilify, Trihexyphenidyl Hydrochloride, Benadryl, Aspirin, Wellbutrin outcomes

Information of the patient in this study:

Age: 28

Gender: male

Conditions: Bipolar Disorder, Depression, Restlessness, Insomnia, Neck Pain, Addiction

Drugs taking:
- Lithium Carbonate (lithium carbonate): used for 2 - 5 years
- Cymbalta (duloxetine hydrochloride): used for 1 - 2 years
- Abilify (aripiprazole): used for 6 - 12 months
- Trihexyphenidyl Hydrochloride (trihexyphenidyl hydrochloride): used for 1 - 6 months
- Benadryl (diphenhydramine hydrochloride): used for 1 - 2 years
- Aspirin (aspirin): used for 1 - 2 years
- Wellbutrin (bupropion hydrochloride): used for < 1 month

Drug interactions have: severe restlessness, moderate insomnia, severe restless leg syndrome

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Restlessness (not able to rest)2 (66.67% of males aged 28 (±5) who take the drugs)
Insomnia (sleeplessness)2 (66.67% of males aged 28 (±5) who take the drugs)
Restless Leg Syndrome (a powerful urge to move your legs)2 (66.67% of males aged 28 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Restlessness in Bipolar Disorder70 (3.82% of males aged 28 (±5) who have Bipolar disorder)
Restlessness in Depression193 (4.14% of males aged 28 (±5) who have Depression)
Restlessness in Restlessness0 (0.00% of males aged 28 (±5) who have Restlessness)
Restlessness in Insomnia27 (1.90% of males aged 28 (±5) who have Insomnia)
Restlessness in Neck Pain2 (3.17% of males aged 28 (±5) who have Neck pain)
Restlessness in Addiction1 (1.18% of males aged 28 (±5) who have Addiction)
Insomnia in Bipolar Disorder127 (6.93% of males aged 28 (±5) who have Bipolar disorder)
Insomnia in Depression237 (5.08% of males aged 28 (±5) who have Depression)
Insomnia in Restlessness9 (3.77% of males aged 28 (±5) who have Restlessness)
Insomnia in Insomnia0 (0.00% of males aged 28 (±5) who have Insomnia)
Insomnia in Neck Pain1 (1.59% of males aged 28 (±5) who have Neck pain)
Insomnia in Addiction2 (2.35% of males aged 28 (±5) who have Addiction)
Restless Leg Syndrome in Bipolar Disorder7 (0.38% of males aged 28 (±5) who have Bipolar disorder)
Restless Leg Syndrome in Depression11 (0.24% of males aged 28 (±5) who have Depression)
Restless Leg Syndrome in Restlessness1 (0.42% of males aged 28 (±5) who have Restlessness)
Restless Leg Syndrome in Insomnia7 (0.49% of males aged 28 (±5) who have Insomnia)
Restless Leg Syndrome in Neck Pain1 (1.59% of males aged 28 (±5) who have Neck pain)
Restless Leg Syndrome in Addiction1 (1.18% of males aged 28 (±5) who have Addiction)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Restlessness in Lithium Carbonate27 (3.31% of males aged 28 (±5) who take Lithium carbonate)
Restlessness in Cymbalta33 (3.94% of males aged 28 (±5) who take Cymbalta)
Restlessness in Abilify80 (5.66% of males aged 28 (±5) who take Abilify)
Restlessness in Trihexyphenidyl Hydrochloride1 (4.76% of males aged 28 (±5) who take Trihexyphenidyl hydrochloride)
Restlessness in Benadryl10 (1.60% of males aged 28 (±5) who take Benadryl)
Restlessness in Aspirin9 (1.13% of males aged 28 (±5) who take Aspirin)
Restlessness in Wellbutrin36 (2.61% of males aged 28 (±5) who take Wellbutrin)
Insomnia in Lithium Carbonate44 (5.39% of males aged 28 (±5) who take Lithium carbonate)
Insomnia in Cymbalta58 (6.92% of males aged 28 (±5) who take Cymbalta)
Insomnia in Abilify77 (5.45% of males aged 28 (±5) who take Abilify)
Insomnia in Trihexyphenidyl Hydrochloride1 (4.76% of males aged 28 (±5) who take Trihexyphenidyl hydrochloride)
Insomnia in Benadryl24 (3.85% of males aged 28 (±5) who take Benadryl)
Insomnia in Aspirin17 (2.13% of males aged 28 (±5) who take Aspirin)
Insomnia in Wellbutrin85 (6.15% of males aged 28 (±5) who take Wellbutrin)
Restless Leg Syndrome in Lithium Carbonate3 (0.37% of males aged 28 (±5) who take Lithium carbonate)
Restless Leg Syndrome in Cymbalta5 (0.60% of males aged 28 (±5) who take Cymbalta)
Restless Leg Syndrome in Abilify3 (0.21% of males aged 28 (±5) who take Abilify)
Restless Leg Syndrome in Trihexyphenidyl Hydrochloride1 (4.76% of males aged 28 (±5) who take Trihexyphenidyl hydrochloride)
Restless Leg Syndrome in Benadryl1 (0.16% of males aged 28 (±5) who take Benadryl)
Restless Leg Syndrome in Aspirin1 (0.13% of males aged 28 (±5) who take Aspirin)
Restless Leg Syndrome in Wellbutrin1 (0.07% of males aged 28 (±5) who take Wellbutrin)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Lithium Carbonate is effectiven/an/an/an/a100.00%
(1 of 1 people)
n/an/an/a
Cymbalta is effectiven/an/an/a100.00%
(1 of 1 people)
n/an/an/an/a
Abilify is effectiven/an/a100.00%
(1 of 1 people)
n/an/an/an/an/a
Trihexyphenidyl Hydrochloride is effectiven/a0.00%
(0 of 1 people)
n/an/an/an/an/an/a
Benadryl is effectiven/an/an/a0.00%
(0 of 1 people)
n/an/an/an/a
Aspirin is effectiven/an/an/a0.00%
(0 of 1 people)
n/an/an/an/a
Wellbutrin is effectiven/an/an/an/an/an/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Insomnia (sleeplessness)Insomnia (sleeplessness)Restless Leg Syndrome (a powerful urge to move your legs)Restless Leg Syndrome (a powerful urge to move your legs)Restless Leg Syndrome (a powerful urge to move your legs)n/an/aDiabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Restless Leg Syndrome (a powerful urge to move your legs)Restless Leg Syndrome (a powerful urge to move your legs)Insomnia (sleeplessness)Insomnia (sleeplessness)Insomnia (sleeplessness)Renal Failure Acute (rapid kidney dysfunction)
Restlessness (not able to rest)Restlessness (not able to rest)Restlessness (not able to rest)Restlessness (not able to rest)Restlessness (not able to rest)Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Sinusitis (inflammation of sinus)
Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
Renal Failure Chronic (long lasting kidney dysfunction)
Pneumonia
Oesophagitis (inflammation of oesophagus)
Pancreatitis (inflammation of pancreas)
Therapeutic Agent Toxicity (poisoning by ability to cure substance)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who have Addiction
- support group for people who have Bipolar Disorder
- support group for people who have Depression
- support group for people who have Insomnia
- support group for people who have Neck Pain
- support group for people who have Restlessness
- support group for people who have Insomnia
- support group for people who have Restless Leg Syndrome
- support group for people who have Restlessness
- support group for people who take Abilify
- support group for people who take Aspirin
- support group for people who take Benadryl
- support group for people who take Cymbalta
- support group for people who take Lithium Carbonate
- support group for people who take Trihexyphenidyl Hydrochloride
- support group for people who take Wellbutrin

Recent conversations of related support groups:

  • Support group for people who have Depression
    There was some discussion last month, but it's died down a bit. Is there anything you could help with or are looking for help with?
  • Support group for people who have Insomnia
    My insomnia was provoked by a 'medicine cocktail', prescribed medications that were contraindicated. I just had a rough experience with Serotonin Syndrome, grateful to be alive.
  • Support group for people who take Abilify
    Welcome Megabob29 and Megabob2946! Same person? :)
  • Support group for people who take Cymbalta
    Now found out I have incompetent vein in leg which may be part of the problem had cystocopy and found cysts in kidney, then developed hypertension but no one will diagnose the pain. Now decided it is the same as diabetic neuropathy but as gp and consultant point out I am a long way from being diabetic with perfect blood glucose so thinks it's just guessing and hope

Can you answer these questions (Ask a question):

More questions for: Abilify, Addiction, Aspirin, Benadryl, Bipolar Disorder, Cymbalta, Depression, Insomnia, Lithium Carbonate, Neck Pain, Restless Leg Syndrome, Restlessness, Trihexyphenidyl Hydrochloride, Wellbutrin

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Comments from related studies:

  • From this study (4 days ago):

  • Mirapex helped to alleviate the severe restlessness (legs, feet, arms, shoulders - partial torso) but caused severe sleep attacks during the day - at work. I fell asleep any time that I got still - in my office, in meetings, while talking with people). I was prescribed Nuvigil to offset the sleep attacks, but taking Mirapex and Nuvigil together made me very sick - I couldn't function at work. Then I developed insomnia and was prescribed sleeping pills. The sleeping pills along with all the other medication was not good. But then I began to be able to stay awake all night, take a shower, go to work, go home - and stay awake another night. So if felt like my body was on a roller
    coaster. I could no longer work. I had to take FMLA leave and use all my sick leave to quit work until I reached retirement age. Since leaving work (8 mths ago), I have been trying to regain my physical and mental equilibrium. I have been taking Mirapex ER for approx. 2 months and the restlessness is MUCH less. I still have sleep attacks whenever I get still (day or night). My quality of life has declined very much because of the sleep attacks.

    Reply

  • From this study (2 weeks ago):

  • For three weeks have had SEVERE hyperglycemia. Am on a pump-basal rates have been increased greatly. Still having issues.

    Reply

  • From this study (2 months ago):

  • doc moc on Apr, 25, 2013:

    BREAK down FOOL!

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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