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What could cause Restlessness, Insomnia, Restless Leg Syndrome for a 33-year old man?

This is a study of Lithium Carbonate, Cymbalta, Abilify, Trihexyphenidyl Hydrochloride, Benadryl, Aspirin, Wellbutrin for a 33 year old male patient who has Bipolar Disorder, Depression, Restlessness, Insomnia, Neck Pain, Addiction. The study is created by eHealthMe based on 3 male patients aged 33 (±5) who take the drugs from FDA and social media.

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Information of the patient in this study:

Age: 28

Gender: male

Conditions: Bipolar Disorder, Depression, Restlessness, Insomnia, Neck Pain, Addiction

Drugs taking:
- Lithium Carbonate (lithium carbonate): used for 2 - 5 years
- Cymbalta (duloxetine hydrochloride): used for 1 - 2 years
- Abilify (aripiprazole): used for 6 - 12 months
- Trihexyphenidyl Hydrochloride (trihexyphenidyl hydrochloride): used for 1 - 6 months
- Benadryl (diphenhydramine hydrochloride): used for 1 - 2 years
- Aspirin (aspirin): used for 1 - 2 years
- Wellbutrin (bupropion hydrochloride): used for < 1 month

Drug interactions have: severe restlessness, moderate insomnia, severe restless leg syndrome

On Jan, 31, 2014: 3 males aged 28 (±5) who reported to have interactions when taking Lithium Carbonate, Cymbalta, Abilify, Trihexyphenidyl Hydrochloride, Benadryl, Aspirin, Wellbutrin are studied

Trend of Lithium Carbonate, Cymbalta, Abilify, Trihexyphenidyl Hydrochloride, Benadryl, Aspirin, Wellbutrin's drug interactions, side effects and effectiveness reports (2842620)

Comparison with this patient's adverse outcomes:

InteractionNumber of reports
among males aged 28 (±5) who take the drugs
Restlessness (not able to rest)2 (66.67%)
Insomnia (sleeplessness)1 (33.33%)
Restless Leg Syndrome (a powerful urge to move your legs)1 (33.33%)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

SymptomNumber of reports
among males aged 28 (±5) who have the condition, regardless of which drug is taken
Restlessness in Bipolar Disorder66 (3.90%)
Restlessness in Depression187 (4.19%)
Restlessness in Restlessness0 (0.00%)
Restlessness in Insomnia27 (2.02%)
Restlessness in Neck Pain2 (3.28%)
Restlessness in Addiction1 (1.27%)
Insomnia in Bipolar Disorder94 (5.56%)
Insomnia in Depression229 (5.14%)
Insomnia in Restlessness9 (4.11%)
Insomnia in Insomnia0 (0.00%)
Insomnia in Neck Pain1 (1.64%)
Insomnia in Addiction2 (2.53%)
Restless Leg Syndrome in Bipolar Disorder5 (0.30%)
Restless Leg Syndrome in Depression10 (0.22%)
Restless Leg Syndrome in Restlessness1 (0.46%)
Restless Leg Syndrome in Insomnia5 (0.37%)
Restless Leg Syndrome in Neck Pain1 (1.64%)
Restless Leg Syndrome in Addiction1 (1.27%)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effectNumber of reports
among males aged 28 (±5) who take the drug
Restlessness in Lithium Carbonate25 (3.27%)
Restlessness in Cymbalta33 (4.08%)
Restlessness in Abilify80 (5.88%)
Restlessness in Trihexyphenidyl Hydrochloride1 (4.76%)
Restlessness in Benadryl10 (1.68%)
Restlessness in Aspirin9 (1.20%)
Restlessness in Wellbutrin36 (2.64%)
Insomnia in Lithium Carbonate34 (4.45%)
Insomnia in Cymbalta55 (6.80%)
Insomnia in Abilify77 (5.66%)
Insomnia in Trihexyphenidyl Hydrochloride1 (4.76%)
Insomnia in Benadryl21 (3.52%)
Insomnia in Aspirin11 (1.47%)
Insomnia in Wellbutrin85 (6.23%)
Restless Leg Syndrome in Lithium Carbonate3 (0.39%)
Restless Leg Syndrome in Cymbalta5 (0.62%)
Restless Leg Syndrome in Abilify3 (0.22%)
Restless Leg Syndrome in Trihexyphenidyl Hydrochloride1 (4.76%)
Restless Leg Syndrome in Benadryl1 (0.17%)
Restless Leg Syndrome in Aspirin1 (0.13%)
Restless Leg Syndrome in Wellbutrin1 (0.07%)

Most common interactions experienced by males aged 28 (±5) in the use of Lithium Carbonate, Cymbalta, Abilify, Trihexyphenidyl Hydrochloride, Benadryl, Aspirin, Wellbutrin:

InteractionNumber of reports
Diabetes Mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)3
Hyperglycaemia (high blood sugar)2
Coma (state of unconsciousness lasting more than six hours)2
Diabetic Ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)2
Sinusitis (inflammation of sinus)2
Renal Failure Acute (rapid kidney dysfunction)2
Diabetic Gastroparesis (paralysis of the muscles of the stomach caused by diabetes)1
Dehydration (dryness resulting from the removal of water)1
Gastritis (inflammation of stomach)1
Gallbladder Disorder1

Most common interactions experienced by males aged 28 (±5) in long term use of Lithium Carbonate, Cymbalta, Abilify, Trihexyphenidyl Hydrochloride, Benadryl, Aspirin, Wellbutrin:

InteractionNumber of reports
Restlessness (not able to rest)1
Insomnia (sleeplessness)1
Restless Leg Syndrome (a powerful urge to move your legs)1

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Related topic: Abilify, Addiction, Aspirin, Benadryl, Bipolar Disorder, Cymbalta, Depression, Insomnia, Lithium Carbonate, Neck Pain, Restless Leg Syndrome, Restlessness, Trihexyphenidyl Hydrochloride, Wellbutrin

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Comments from related studies:

  • From this study (4 weeks ago):

  • Never a clot but newly prescribed medicine Pristiq and I have Factor V, Type 1 Diabetes, high cholesterol and use a fentanyl patch and these were all warnings on Pristiq. I take wellbutrin 300 and Zoloft and Prozac didn't work.

    I see an endocrinologist, neurologist, family practice, pain management. My depression is because of pain. I've only been to one pain doctor and I must have a tolerance to opiates. I've tried oxycodone 15mg x many, dilaudid 8 mg x many, morphine 30 x many, Opana Er x many. Not all at once and always take prescribed amount but it never works. Been prescribed the same garbage for 6 years and have had pain epidurals and radio frequency ablations. Was pretty exited about laser surgery and then I was told they don't take my insurance when I have a BCBS PPO

    I'm afraid doctors like me psychiatrist don't look atoll my medical history before prescribing things like Pristiq.

    Reply

  • From this study (1 month ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness. WBCs run 10.5 to 13.0 consistently. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increased & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

  • From this study (1 month ago):

  • Have been on Gabapentin for years now. For the past 3-4 yrs, I have had a chronically elevated WBC without evidence of illness.WBCs run 10.5 tp 13.0 consistanly. Even when on antibiotics, has not dropped below 10.5. Am now wondering if this could be related to Gabapentin. The elevated WBCs have resulted in delay of care for back pain issues. At one time, I tried to get off of gabapentin - was titrating the dose(c my provider's permission). I noticed that the Restless Leg Syndrome that I had been experiencing had disappeared with the lower dose of Gabapentin. Unfortunately, the Meralgia Paresthetica synotoms increase & had to increase the Gabapentin back up. RLS came back with increased dose.

    Reply

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

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