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A study for a 47-year old woman who takes Cymbalta, Suboxone

Summary: 35 female patients aged 47 (±5) who take the same drugs are studied.

This is a personalized study for a 47 year old female patient who has Depression, Opiate withdrawal. The study is created by eHealthMe based on reports from FDA and social media.

 

 

 

 

What are the drugs

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from 49,362 Cymbalta users)

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. (latest outcomes from 8,295 Suboxone users)

What are the conditions

Depression can be treated by Zoloft, Cymbalta, Prozac, Lexapro, Celexa, Wellbutrin Xl. (latest reports from 277,322 Depression patients)

Opiate withdrawal can be treated by Suboxone, Methadone Hydrochloride, Subutex, Clonidine Hydrochloride, Buprenorphine Hydrochloride, Methadose. (latest reports from 788 Opiate Withdrawal patients)

What is the symptom

Muscle Twitching has been reported by people with depression, pain, multiple sclerosis, stress and anxiety, high blood pressure. (latest reports from 11,065 Muscle Twitching patients)

On Feb, 15, 2015: 35 females aged 41 (±5) who take Cymbalta, Suboxone are studied

Cymbalta, Suboxone outcomes

Information of the patient in this study:

Age: 41

Gender: female

Conditions: Depression, Opiate withdrawal

Drugs taking:
- Cymbalta - 60MG (duloxetine hydrochloride): used for 1 - 2 years
- Suboxone - 8MG;2MG (buprenorphine hydrochloride; naloxone hydrochloride): used for < 1 month

Drug interactions have: moderate muscle twitching

eHealthMe real world results:

Comparison with this patient's adverse outcomes:

InteractionNumber of reports on eHealthMe
Muscle Twitching2 (5.71% of females aged 41 (±5) who take the drugs)

(as an adverse outcome could be a symptom of a condition, additional studies are listed to help identify the cause: for example, regardless of which drug is taken, how many female HBP patients aged 50 (±5) have nausea)

Symptom (click a symptom for in-depth analysis)Number of reports on eHealthMe
Muscle Twitching in Depression107 (0.53% of females aged 41 (±5) who have Depression)
Muscle Twitching in Opiate Withdrawal1 (1.33% of females aged 41 (±5) who have Opiate withdrawal)

(as an adverse outcome could be a side effect of a drug, additional studies are listed to help identify the cause: for example, how many female Aspirin users aged 50 (±5) have nausea)

Side effect (click a side effect for in-depth analysis)Number of reports on eHealthMe
Muscle Twitching in Cymbalta59 (0.90% of females aged 41 (±5) who take Cymbalta)
Muscle Twitching in Suboxone13 (1.55% of females aged 41 (±5) who take Suboxone)

Drug effectiveness over time :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Cymbalta is effective0.00%
(0 of 1 people)
n/an/a0.00%
(0 of 3 people)
0.00%
(0 of 2 people)
n/an/an/a
Suboxone is effective100.00%
(1 of 1 people)
0.00%
(0 of 1 people)
0.00%
(0 of 1 people)
100.00%
(1 of 1 people)
100.00%
(2 of 2 people)
n/an/an/a

Most common drug interactions over time * :

< 1 month1 - 6 months6 - 12 months1 - 2 years2 - 5 years5 - 10 years10+ yearsnot specified
Hallucination, Visual (seeing things that aren't there)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Suicide AttemptFoot, Leg, And Ankle SwellingBlister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)Exhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)n/aJoint Swelling
Joint SwellingHallucination, Visual (seeing things that aren't there)DepressionSwellingDrug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Tremor (trembling or shaking movements in one or more parts of your body)Joint SwellingSweating Fever (fever with sweating)Muscle TwitchingElectric ShockDepression
Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)Tremor (trembling or shaking movements in one or more parts of your body)Clamminess (moist, sticky, and cold to the touch)Sweating Fever (fever with sweating)Exhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)Pain
ConstipationConstipationClamminess (moist, sticky, and cold to the touch)Children And Weight ProblemsConvulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Muscle TwitchingSwellingAlanine Aminotransferase Increased
Urinary Incontinence (inability to control the flow of urine and involuntary urination)Suicide AttemptGait Disturbance
Foot, Leg, And Ankle SwellingExhaustion, Fatigue, Lethargy, Tiredness, Weariness (feeling of tiredness)Dysstasia (difficulty in standing)
DepressionMuscle Spasms (muscle contraction)
Oedema Peripheral (superficial swelling)

* Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

You can also:

You are not alone! Join a related mobile support group:
- support group for people who take Cymbalta and have Muscle Twitching
- support group for people who take Suboxone and have Muscle Twitching
- support group for people who have Muscle Twitching and Depression
- support group for people who have Muscle Twitching and Opiate withdrawal
- support group for people who have Depression
- support group for people who have Opiate Withdrawal
- support group for people who have Muscle Twitching
- support group for people who take Cymbalta
- support group for people who take Suboxone

Recent conversations of related support groups:

  • Support group for people who have Depression
    I'm taking 100 mg of Zoloft a day. It helps with depression but I am having acid reflux and all over muscle pain. Has anyone else experienced this?
  • Support group for people who take Cymbalta
    Now found out I have incompetent vein in leg which may be part of the problem had cystocopy and found cysts in kidney, then developed hypertension but no one will diagnose the pain. Now decided it is the same as diabetic neuropathy but as gp and consultant point out I am a long way from being diabetic with perfect blood glucose so thinks it's just guessing and hope
  • Support group for people who take Suboxone
    I've been trying to come off suboxone and I'm tapering myself off. Is there a thread in here for people like me.

Can you answer these questions (Ask a question):

  • Anyone else get endometrial hyperplasia frrom citalipram? i read this med could cause this cancer.
    I just find it odd that 2012, I didn't need a neck surgery, and now they want to do spine fusion. http://www.spine-health.com/treatment/spinal-fusion/interbody-cages-spine-fusion
  • Does anyone else suffer sleep hyperhidrosis during rem sleep? (3 answers)
    I have terrible night sweats only during REM sleep. Never any other time, just during REM sleep. This is keeping me from getting any decent sleep at all.
  • What do i do when i have hit a road block? (1 answer)
    I had a severe reaction to Cymbalta and ended up in the ER with the worse migraine of my life. Since then I have had double/blurry vision along with other side effects. We questioned the continuation of Cymbalta, however were repeatedly told to continue with it by the ER, doctor on call, and my primary dr. We have done tons of testing with doctors, eye specialists, neurologists, etc. since the ER and they don't seem to have any answers. In the meantime I am unable to drive, work, etc and am waiting for some type of diagnosis. The only thing I am able to do is get more and more tests done. This is really adding up and now I am traveling quite a distance to get to "more knowledgeable specialists". Until I have a diagnosis I am not able to get long term disability, so what is a person to do? I have used up all my savings and am beyond frustrated. The last Drs office I scheduled with asked if I was involved in a lawsuit after describing my symptoms to the appointment specialist. If I was she said that they wouldn't see me. Then the Dr asked the same question at the beginning of my appointment. He said if there wasn't a lawsuit involved that he would treat me, but if there was he would refer me somewhere else. So what do I do now that I have hit a road block? Are they trying to indirectly tell me to sue? Who to sue - Cymbalta or previous doctors - or all the above? Suggestions anyone?
  • Can indigestion be associated with mittelschmerz?
    Every other month I have pain on the right side of my pelvic area about 2 weeks after my period. I also feel very bloated, gassy, and have indigestion. Could this be mittelschmerz?
  • Why nothing i do stop my breath from smelling bad. (1 answer)
    I have been doing everything to find out what's causing is but I just can't find anyone in my area to help me. I've had and upper and lower GI, Sinus surgery. go to the perio every 3 month.. I don't know what else to do.. I also take shot for allery. I'm allergic to wheat, yeast, corn, dairy and soy

More questions for: Depression, Muscle Twitching, Opiate withdrawal

You may be interested at these reviews (Write a review):

  • Are you mental on methadone
    My doctor changed my pain medication back in May of 2014 . I was pleased with how well it handle my back pain and was pleased with how inexpensive it was. My husband had been using the same drug with great results. It wasn't until about a month later I started to notice just feelings of sadness. I didn't think too much of it but then I would get such strong feelings of despair really bad that I would just cry. I also started getting a lot of panic attacks I had so much anxiety at times it prevented me from doing things. At one point I really thought I was having some sort of break down, but the feelings would have highs and lows and sometimes I would have a day with out them. Eventually after being on them for 7 months I went to my doctor and asked if it were possible I was experiencing these feelings from the Methadone. He wasn't sure but with it all happening right after I started taking them he decided to put me on something else. It's been about three weeks and even though the feelings are still there they are not as strong and seem to be passing. I hope as time goes I will feel like myself again and hope never to have to experience something like that again.
  • Ears thundering after suboxone or any opiate
    Anyone notice the thundering in your ears after taking suboxone. Larger doses mostly and it actually happens with any opiate. It's a rumbling in the ears, I did read that hearing loss and opiates were connnected. hmmm
  • Terrible excessive sweating from hydrochlorothiazide
    I guess I fit the profile of who gets excessive sweating from HCTZ. I am a 65 year old female and suffered from excessive sweating for two years. With just very little exertion, I would pour sweat from the top of my head. It would run into my face and all over my hair. My hair would be ringing wet. I had heavy perspiration in the groin area and down my back also. I had to change clothing 2-3 times a day and wash up or shower that many times also. The doctor tried changing my Cymbalta and put me on Wellbutrin instead. It did absolutely no good. I went off the wellbutrin and back onto the Cymbalta. I did some research and saw that HCTZ could cause excessive sweating. Both my doctor and my pharmacist said that they had never heard of that. I went off the HCTZ, and my sweating stopped almost immediately. My doctor and my pharmacist were very surprised. I'm one of those people who frequently have different reactions to drugs than are typical. If you're having excessive perspiration and are on HCTZ, try going off of it. It just may be the culprit!
  • Ulcerative colitis from suboxone?
    Anyone else out there experiencing ulcerative colitis after multiple yearprescribed Suboxone? Suboxone stole a large portion of my life, and now I am considering going on a full-agonist analgesic until the buprenorphine bond has broken, and no more presence of it in my plasma. Insane!
  • Cymbalta side effects
    Starting Cymbalta, side effects were dizzy,felt drugged. Helped with Arthritis pain. About six weeks after i started i developed rectal bleeding.Doctor had me stop Cymbalta and use Tramadol as needed for withdrawal.

More reviews for: Depression, Muscle Twitching, Opiate withdrawal

Comments from related studies:

  • From this study (5 months ago):

  • For the last 20-30 years I go through cycles where I am just too lethargic to function. I suffer from severe brain fog, lack of direction, sleep way too much, and am in an almost vegetative state and this could last anywhere from a few weeks to a few years. I do not believe it to be depression as I do not feel depressed. I feel unwell and quite often experience low grade fevers. I also have hemochromatosis and thyroid nodules, as well as Ehlers-Danlos Syndrome and Bipolar Disorder and AV Nodal Re-entrant Tachycardia

    Reply

  • From this study (2 years ago):

  • I am having terrible symtoms anytime I exert myself physically

    Reply

  • From this study (2 years ago):

  • I was on Sertraline, switched to Cymbalta and added the Gabapentin. So instead of one change in meds, we dropped one and added 2. So I'm not sure if it's the Cybalta or the Gabapentin causing the edema.

    Reply

Post a new comment    OR    Read more comments

Related drug interaction studies:

Drug effectiveness in real world:

In-depth study of side effects (who have it, when it happens and how):

In-depth study of symptoms:

Complete drug side effects:

Alternative drugs:

Drugs associated with:

Conditions associated with:

NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

   

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