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From FDA reports: side effects of Depakine Chrono Tablets 500 Mg

This is a study of Depakine Chrono Tablets 500 Mg side effects. The study is created by eHealthMe based on reports of 20,435 people who take the same drug and have side effectsfrom FDA.

On Jan, 24, 2015: 20,435 people who reported to have side effects when taking Depakine Chrono Tablets 500 Mg are studied

Trend of Depakine Chrono Tablets 500 Mg's drug interactions, side effects, and effectiveness reports (2736779)

Information of the patient in this study:

Gender: male

Conditions: Drug Exposure During Pregnancy

Drugs taking:
- Depakine Chrono Tablets 500 Mg

Side effects have: Drug Exposure During Pregnancy, Dysmorphism, Gastrooesophageal Reflux Disease, Hypermobility Syndrome

eHealthMe real world results:

For people in general (regardless of gender or age):

Comparison with this patient's adverse outcomes:

Side effectNumber of reports
Drug Exposure During Pregnancy768 (3.76%)
Dysmorphism (difference of body structure that is suggestive of a congenital disorder)10 (0.05%)
Gastrooesophageal Reflux Disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)96 (0.47%)
Hypermobility Syndrome (abnormalities cause abnormal stress on a joint or many joint)4 (0.02%)

Most common side effects experienced by people in the use of Depakine Chrono Tablets 500 Mg:

Side effectNumber of reports
Pyrexia (fever)3,229
Nausea (feeling of having an urge to vomit)2,300
Vomiting Nos1,876
Asthenia (weakness)1,687
Fatigue (feeling of tiredness)1,562
Liver Function Tests Nos Abnormal1,426
Condition Aggravated (worse condition)1,406
Malaise (a feeling of general discomfort or uneasiness)1,318
Dizziness (exc Vertigo)1,182
Dermatitis Nos1,091

Most common side effects experienced by people in long term use of Depakine Chrono Tablets 500 Mg:

Side effectNumber of reports
Economic Problem158
Tardive Dyskinesia (a disorder that involves involuntary movements)156
Extrapyramidal Disorder (involuntary muscle spasms in the face and neck)148
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)114
Nervous System Disorder (a general class of medical conditions affecting the nervous system)114
Activities Of Daily Living Impaired108
Deformity (disfigurement)86
Nausea (feeling of having an urge to vomit)74
Movement Disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)72

Comments for this study:

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NOTE: The study is based on active ingredients. Other drugs that have the same active ingredients are also considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.


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